JP2006524677A5 - - Google Patents
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- Publication number
- JP2006524677A5 JP2006524677A5 JP2006506554A JP2006506554A JP2006524677A5 JP 2006524677 A5 JP2006524677 A5 JP 2006524677A5 JP 2006506554 A JP2006506554 A JP 2006506554A JP 2006506554 A JP2006506554 A JP 2006506554A JP 2006524677 A5 JP2006524677 A5 JP 2006524677A5
- Authority
- JP
- Japan
- Prior art keywords
- diphenylpropylamine
- diphenylpropylamine according
- alkyl
- group
- phenylpropanamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- KISZTEOELCMZPY-UHFFFAOYSA-N 3,3-diphenylpropylamine Chemical compound C=1C=CC=CC=1C(CCN)C1=CC=CC=C1 KISZTEOELCMZPY-UHFFFAOYSA-N 0.000 claims 16
- 229910052736 halogen Inorganic materials 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- -1 2-hydroxy-5-trifluoromethylphenyl Chemical group 0.000 claims 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 208000012931 Urologic disease Diseases 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 150000001721 carbon Chemical group 0.000 claims 2
- 125000005843 halogen group Chemical group 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 229910052757 nitrogen Inorganic materials 0.000 claims 2
- 208000014001 urinary system disease Diseases 0.000 claims 2
- AQFLVLHRZFLDDV-UHFFFAOYSA-N 1-phenylpropan-1-amine Chemical compound CCC(N)C1=CC=CC=C1 AQFLVLHRZFLDDV-UHFFFAOYSA-N 0.000 claims 1
- XJQYYTAEVPGXIQ-UHFFFAOYSA-N 3-[2-methoxy-5-(trifluoromethyl)phenyl]-3-phenyl-n,n-di(propan-2-yl)propan-1-amine Chemical compound COC1=CC=C(C(F)(F)F)C=C1C(CCN(C(C)C)C(C)C)C1=CC=CC=C1 XJQYYTAEVPGXIQ-UHFFFAOYSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 229910052731 fluorine Inorganic materials 0.000 claims 1
- 125000001153 fluoro group Chemical group F* 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46537203P | 2003-04-25 | 2003-04-25 | |
| PCT/IB2004/001333 WO2004096751A1 (en) | 2003-04-25 | 2004-04-15 | Halogen substituted 3,3-diphenylpropylamines (tolterodine) having antimuscarinic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006524677A JP2006524677A (ja) | 2006-11-02 |
| JP2006524677A5 true JP2006524677A5 (https=) | 2007-04-05 |
Family
ID=33418235
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006506554A Withdrawn JP2006524677A (ja) | 2003-04-25 | 2004-04-15 | 抗ムスカリン活性を有するハロゲン置換３，３−ジフェニルプロピルアミン（トルテロジン） |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20050004223A1 (https=) |
| EP (1) | EP1620389A1 (https=) |
| JP (1) | JP2006524677A (https=) |
| BR (1) | BRPI0409653A (https=) |
| CA (1) | CA2523226A1 (https=) |
| MX (1) | MXPA05011509A (https=) |
| WO (1) | WO2004096751A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| DE60230546D1 (de) * | 2001-10-26 | 2009-02-05 | Pharmacia & Upjohn Co Llc | Quaternäre ammoniumverbindungen und deren verwendung als antimuscarinische wirkstoffe |
| DE10315917A1 (de) * | 2003-04-08 | 2004-11-18 | Schwarz Pharma Ag | Hochreine Basen von 3,3-Diphenylpropylaminmonoestern |
| WO2004096751A1 (en) * | 2003-04-25 | 2004-11-11 | Pharmacia & Upjohn Company Llc | Halogen substituted 3,3-diphenylpropylamines (tolterodine) having antimuscarinic activity |
| KR101029643B1 (ko) | 2004-07-24 | 2011-04-15 | 일동제약주식회사 | 엔-메틸-3,3-디페닐프로필아민의 제조방법 |
| KR100647068B1 (ko) | 2005-09-15 | 2006-11-23 | 하나제약 주식회사 | 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법 |
| CN100430370C (zh) * | 2006-11-03 | 2008-11-05 | 华东理工大学 | 一种丙胺衍生物及其在制备托莫西汀中的应用 |
| KR101270122B1 (ko) | 2007-11-01 | 2013-05-31 | 어큐셀라 인코포레이티드 | 안과 질환 및 장애를 치료하기 위한 아민 유도체 화합물 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8800207D0 (sv) | 1988-01-22 | 1988-01-22 | Kabivitrum Ab | Nya aminer, deras anvendning och framstellning |
| SE9203318D0 (sv) | 1992-11-06 | 1992-11-06 | Kabi Pharmacia Ab | Novel 3,3-diphenylpropylamines, their use and preparation |
| EP0957073A1 (en) * | 1998-05-12 | 1999-11-17 | Schwarz Pharma Ag | Novel derivatives of 3,3-diphenylpropylamines |
| DE60230546D1 (de) * | 2001-10-26 | 2009-02-05 | Pharmacia & Upjohn Co Llc | Quaternäre ammoniumverbindungen und deren verwendung als antimuscarinische wirkstoffe |
| WO2004096751A1 (en) * | 2003-04-25 | 2004-11-11 | Pharmacia & Upjohn Company Llc | Halogen substituted 3,3-diphenylpropylamines (tolterodine) having antimuscarinic activity |
-
2004
- 2004-04-15 WO PCT/IB2004/001333 patent/WO2004096751A1/en not_active Ceased
- 2004-04-15 EP EP04727624A patent/EP1620389A1/en not_active Withdrawn
- 2004-04-15 BR BRPI0409653-3A patent/BRPI0409653A/pt not_active IP Right Cessation
- 2004-04-15 MX MXPA05011509A patent/MXPA05011509A/es not_active Application Discontinuation
- 2004-04-15 JP JP2006506554A patent/JP2006524677A/ja not_active Withdrawn
- 2004-04-15 CA CA002523226A patent/CA2523226A1/en not_active Abandoned
- 2004-04-26 US US10/832,555 patent/US20050004223A1/en not_active Abandoned
-
2005
- 2005-08-25 US US11/212,330 patent/US7119121B2/en not_active Expired - Fee Related
-
2006
- 2006-08-24 US US11/466,814 patent/US7291648B2/en not_active Expired - Fee Related
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