JP2006523720A - 胸腺再生前の移植片に対する寛容 - Google Patents
胸腺再生前の移植片に対する寛容 Download PDFInfo
- Publication number
- JP2006523720A JP2006523720A JP2006513099A JP2006513099A JP2006523720A JP 2006523720 A JP2006523720 A JP 2006523720A JP 2006513099 A JP2006513099 A JP 2006513099A JP 2006513099 A JP2006513099 A JP 2006513099A JP 2006523720 A JP2006523720 A JP 2006523720A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- patient
- cell
- donor
- thymus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1808—Epidermal growth factor [EGF] urogastrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2013—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2046—IL-7
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/419,039 US20040037816A1 (en) | 1999-04-15 | 2003-04-18 | Graft acceptance through manipulation of thymic regeneration |
US52700103P | 2003-12-05 | 2003-12-05 | |
US10/749,119 US20040258672A1 (en) | 1999-04-15 | 2003-12-30 | Graft acceptance through manipulation of thymic regeneration |
PCT/US2004/011919 WO2004094988A2 (en) | 2003-04-18 | 2004-04-19 | Tolerance to graft prior to thymic regeneration |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2006523720A true JP2006523720A (ja) | 2006-10-19 |
Family
ID=33314188
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2006513099A Withdrawn JP2006523720A (ja) | 2003-04-18 | 2004-04-19 | 胸腺再生前の移植片に対する寛容 |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040258672A1 (ko) |
EP (2) | EP1620125A4 (ko) |
JP (1) | JP2006523720A (ko) |
KR (1) | KR20060025134A (ko) |
AU (1) | AU2004233019A1 (ko) |
CA (1) | CA2528503A1 (ko) |
WO (2) | WO2004094988A2 (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070274946A1 (en) * | 1999-04-15 | 2007-11-29 | Norwood Immunoloty, Ltd. | Tolerance to Graft Prior to Thymic Reactivation |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
WO2004094599A2 (en) * | 2003-04-18 | 2004-11-04 | Norwood Immunology, Ltd. | Disease prevention and vaccination following thymic reactivation |
US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
CA2619503A1 (en) * | 2005-06-28 | 2007-01-04 | Robert F. Casper | Aromatase inhibitors for emergency contraception |
CN103292469A (zh) * | 2011-06-28 | 2013-09-11 | 李君� | 一种温水锅炉、蒸汽换热锅炉的节能减排装置 |
WO2022011284A1 (en) * | 2020-07-10 | 2022-01-13 | Ohio State Innovation Foundation | Epidermal growth factor-like 7 peptide and uses thereof |
Family Cites Families (72)
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US43245A (en) * | 1864-06-21 | Maurice vebgnes | ||
US434571A (en) * | 1890-08-19 | Filter | ||
FR2238700B1 (ko) * | 1973-07-24 | 1977-10-14 | Takeda Chemical Industries Ltd | |
JPS5726506B2 (ko) * | 1974-03-08 | 1982-06-04 | ||
CS180644B2 (en) * | 1973-09-29 | 1978-01-31 | Takeda Chemical Industries Ltd | Process for preparing nonapeptides |
US4005063A (en) * | 1973-10-11 | 1977-01-25 | Abbott Laboratories | [Des-gly]10 -GnRH nonapeptide anide analogs in position 6 having ovulation-inducing activity |
US3992365A (en) * | 1973-11-01 | 1976-11-16 | Burroughs Wellcome Co. | Agonist analogues of luteinizing hormone releasing hormone |
JPS50142563A (ko) * | 1974-04-26 | 1975-11-17 | ||
NL7505590A (nl) * | 1974-05-18 | 1975-11-20 | Hoechst Ag | Werkwijze voor het bereiden van peptiden met lh-rh/fsh-rh-werking. |
AU497512B2 (en) * | 1975-04-15 | 1978-12-14 | Ici Australia Limited | Nona and deca-peptides |
US4018726A (en) * | 1975-06-12 | 1977-04-19 | Andrew Victor Schally | [D-Phe6 ]-LH-RH and intermediates therefor |
US4024121A (en) * | 1976-01-27 | 1977-05-17 | Schally Andrew Victor | (Pyro)-Glu-His-Trp-D-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHR and intermediates |
US4049805A (en) * | 1975-09-30 | 1977-09-20 | Akzona Incorporated | Steroidal erythropoietic agents and therapeutic compositions and methods |
DE2617646C2 (de) * | 1976-04-22 | 1986-07-31 | Hoechst Ag, 6230 Frankfurt | Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
GB1524747A (en) * | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
US4089946A (en) * | 1976-06-07 | 1978-05-16 | American Home Products Corporation | Claudogenic-interceptive nonapeptides |
US4218439A (en) * | 1977-07-14 | 1980-08-19 | The Salk Institute For Biological Studies | Peptide which inhibits gonadal function |
DE2905502C2 (de) * | 1979-02-14 | 1982-07-15 | Hoechst Ag, 6000 Frankfurt | Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin |
US4608251A (en) * | 1984-11-09 | 1986-08-26 | Pitman-Moore, Inc. | LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues |
US5003011A (en) * | 1985-04-09 | 1991-03-26 | The Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
US4866160A (en) * | 1985-04-09 | 1989-09-12 | The Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
US5073624A (en) * | 1985-04-09 | 1991-12-17 | Administrators Of The Tulane Educational Fund | Therapeutic decapeptides |
US4642332A (en) * | 1985-04-26 | 1987-02-10 | The Board Of Regents, The University Of Texas System | Effective hormonal peptides: D-3-Pal6 -LHRH |
US4656247A (en) * | 1985-04-26 | 1987-04-07 | Board Of Regents, The University Of Texas System | Effective hormonal peptides: D-3-QA1 6-LHRH |
US4775361A (en) * | 1986-04-10 | 1988-10-04 | The General Hospital Corporation | Controlled removal of human stratum corneum by pulsed laser to enhance percutaneous transport |
US4992421A (en) * | 1988-04-19 | 1991-02-12 | Abbott Laboratories | Luteinizing hormone releasing hormone antagonist |
US5258492A (en) * | 1988-10-21 | 1993-11-02 | The Administrators Of The Tulane Educational Fund | LHRH analogues with cytotoxic moieties at the sixth position |
US5399493A (en) * | 1989-06-15 | 1995-03-21 | The Regents Of The University Of Michigan | Methods and compositions for the optimization of human hematopoietic progenitor cell cultures |
US5144019A (en) * | 1989-06-21 | 1992-09-01 | City Of Hope | Ribozyme cleavage of HIV-I RNA |
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US5199942A (en) * | 1991-06-07 | 1993-04-06 | Immunex Corporation | Method for improving autologous transplantation |
US5624823A (en) * | 1991-11-22 | 1997-04-29 | The General Hospital Corporation | DNA encoding procine interleukin-10 |
CA2121370C (en) * | 1991-11-22 | 2003-03-18 | David H. Sachs | Specific tolerance in transplantation |
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US5658564A (en) * | 1992-02-19 | 1997-08-19 | The General Hospital Corporation | Xenograft thymus |
US5876708A (en) * | 1992-02-19 | 1999-03-02 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
US5643252A (en) * | 1992-10-28 | 1997-07-01 | Venisect, Inc. | Laser perforator |
US5614502A (en) * | 1993-01-15 | 1997-03-25 | The General Hospital Corporation | High-pressure impulse transient drug delivery for the treatment of proliferative diseases |
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US20010009663A1 (en) * | 1993-09-13 | 2001-07-26 | Suzanne T. Ildstad | Non-lethal methods for conditioning a recipient for bone marrow transplantation |
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US5506207A (en) * | 1994-03-18 | 1996-04-09 | The Salk Institute For Biological Studies | GNRH antagonists XIII |
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EP0957980A4 (en) * | 1996-11-27 | 2000-03-29 | Gen Hospital Corp | DELIVERY OF COMPOUNDS BY MEANS OF IMPULSE TRANSIENT PHENOMENES |
US5985892A (en) * | 1998-04-02 | 1999-11-16 | Merck & Co., Ltd. | Antagonists of gonadotropin releasing hormone |
US6248329B1 (en) * | 1998-06-01 | 2001-06-19 | Ramaswamy Chandrashekar | Parasitic helminth cuticlin nucleic acid molecules and uses thereof |
AU2980900A (en) * | 1999-02-04 | 2000-08-25 | General Hospital Corporation, The | Methods for human allografting |
AUPP977899A0 (en) * | 1999-04-15 | 1999-05-13 | Monash University | Improvement of t cell mediated immunity |
AUPR074500A0 (en) * | 2000-10-13 | 2000-11-09 | Monash University | Treatment of t cell disorders |
US20020136704A1 (en) * | 1999-04-15 | 2002-09-26 | Richard Boyd | Diagnostic indicator of thymic function |
WO2002031195A1 (en) * | 2000-10-11 | 2002-04-18 | Duke University | Assay for detecting and quantitating mouse t cell receptor excision circles |
EP1345574A4 (en) * | 2000-10-13 | 2006-05-31 | Univ Monash | IMPROVING ACCEPTANCE OF TRANSPLANTS BY CONTROLLING THYME REGENERATION |
AP2003002800A0 (en) * | 2000-10-13 | 2003-06-30 | Richard Boyd | Hematopoietic stem cell gene therapy |
US6759551B1 (en) * | 2000-11-03 | 2004-07-06 | Bayer Cropscience S.A. | Chiral (s- or r-methylphenylglycine) amino acid crystal and method for preparing same |
US20050043245A1 (en) * | 2003-08-11 | 2005-02-24 | Siler -Khodr Theresa M. | Non-mammalian GnRH analogs and uses thereof in the immune system |
-
2003
- 2003-12-30 US US10/749,119 patent/US20040258672A1/en not_active Abandoned
-
2004
- 2004-04-19 WO PCT/US2004/011919 patent/WO2004094988A2/en active Application Filing
- 2004-04-19 EP EP04759973A patent/EP1620125A4/en not_active Withdrawn
- 2004-04-19 KR KR1020057019859A patent/KR20060025134A/ko not_active Application Discontinuation
- 2004-04-19 WO PCT/US2004/011920 patent/WO2004094649A2/en active Application Filing
- 2004-04-19 EP EP04750271A patent/EP1619952A4/en not_active Withdrawn
- 2004-04-19 JP JP2006513099A patent/JP2006523720A/ja not_active Withdrawn
- 2004-04-19 CA CA002528503A patent/CA2528503A1/en not_active Abandoned
- 2004-04-19 AU AU2004233019A patent/AU2004233019A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2004094988A2 (en) | 2004-11-04 |
WO2004094649A2 (en) | 2004-11-04 |
EP1619952A2 (en) | 2006-02-01 |
KR20060025134A (ko) | 2006-03-20 |
EP1620125A2 (en) | 2006-02-01 |
CA2528503A1 (en) | 2004-11-04 |
AU2004233019A1 (en) | 2004-11-04 |
US20040258672A1 (en) | 2004-12-23 |
EP1619952A4 (en) | 2009-07-22 |
WO2004094988A3 (en) | 2005-12-01 |
EP1620125A4 (en) | 2009-11-04 |
WO2004094649A3 (en) | 2005-12-01 |
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Legal Events
Date | Code | Title | Description |
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