JP2006523224A5 - - Google Patents

Download PDF

Info

Publication number
JP2006523224A5
JP2006523224A5 JP2006508920A JP2006508920A JP2006523224A5 JP 2006523224 A5 JP2006523224 A5 JP 2006523224A5 JP 2006508920 A JP2006508920 A JP 2006508920A JP 2006508920 A JP2006508920 A JP 2006508920A JP 2006523224 A5 JP2006523224 A5 JP 2006523224A5
Authority
JP
Japan
Prior art keywords
antigen
composition
vsv
dna plasmid
cytokine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2006508920A
Other languages
English (en)
Japanese (ja)
Other versions
JP2006523224A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/006089 external-priority patent/WO2004093906A1/en
Publication of JP2006523224A publication Critical patent/JP2006523224A/ja
Publication of JP2006523224A5 publication Critical patent/JP2006523224A5/ja
Withdrawn legal-status Critical Current

Links

JP2006508920A 2003-03-26 2004-03-23 免疫原性組成物および方法 Withdrawn JP2006523224A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US45787603P 2003-03-26 2003-03-26
US54673304P 2004-02-23 2004-02-23
PCT/US2004/006089 WO2004093906A1 (en) 2003-03-26 2004-03-23 Immunogenic composition and methods

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2011154426A Division JP5635950B2 (ja) 2003-03-26 2011-07-13 免疫原性組成物および方法

Publications (2)

Publication Number Publication Date
JP2006523224A JP2006523224A (ja) 2006-10-12
JP2006523224A5 true JP2006523224A5 (https=) 2007-05-24

Family

ID=42828775

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006508920A Withdrawn JP2006523224A (ja) 2003-03-26 2004-03-23 免疫原性組成物および方法

Country Status (13)

Country Link
US (2) US20070134200A1 (https=)
EP (1) EP1605971B1 (https=)
JP (1) JP2006523224A (https=)
CN (1) CN1764474B (https=)
AT (1) ATE468859T1 (https=)
AU (1) AU2004231464B2 (https=)
BR (1) BRPI0408779A (https=)
CA (1) CA2517010C (https=)
DK (1) DK1605971T3 (https=)
MX (1) MXPA05008526A (https=)
NZ (1) NZ542652A (https=)
PL (1) PL1605971T3 (https=)
WO (1) WO2004093906A1 (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6861422B2 (en) 2003-02-26 2005-03-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
PT1605971E (pt) * 2003-03-26 2010-07-29 Wyeth Llc COMPOSIÆO IMUNOGéNICA E MéTODOS
TW200613554A (en) 2004-06-17 2006-05-01 Wyeth Corp Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
DE102004029784A1 (de) 2004-06-21 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue 2-Benzylaminodihydropteridinone, Verfahren zur deren Herstellung und deren Verwendung als Arzneimittel
DE102004033670A1 (de) 2004-07-09 2006-02-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel
US20060058311A1 (en) 2004-08-14 2006-03-16 Boehringer Ingelheim International Gmbh Combinations for the treatment of diseases involving cell proliferation
US7728134B2 (en) 2004-08-14 2010-06-01 Boehringer Ingelheim International Gmbh Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
US20060035903A1 (en) 2004-08-14 2006-02-16 Boehringer Ingelheim International Gmbh Storage stable perfusion solution for dihydropteridinones
US7759485B2 (en) 2004-08-14 2010-07-20 Boehringer Ingelheim International Gmbh Process for the manufacture of dihydropteridinones
US20060074088A1 (en) 2004-08-14 2006-04-06 Boehringer Ingelheim International Gmbh Dihydropteridinones for the treatment of cancer diseases
EP1630163A1 (de) 2004-08-25 2006-03-01 Boehringer Ingelheim Pharma GmbH & Co.KG Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004058337A1 (de) 2004-12-02 2006-06-14 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung von annelierten Piperazin-2-on Derivaten
WO2006110344A1 (en) * 2005-04-07 2006-10-19 Wyeth Novel methods for inducing an immune response against human immunodefiency virus
US7439358B2 (en) 2006-02-08 2008-10-21 Boehringer Ingelheim International Gmbh Specific salt, anhydrous and crystalline form of a dihydropteridione derivative
EP2185559A1 (en) 2007-08-03 2010-05-19 Boehringer Ingelheim International GmbH Crystalline form of a dihydropteridione derivative
BRPI1009616B8 (pt) * 2009-06-08 2021-05-25 Univ Western Ontario plataforma de imunização para uso em uma estratégia de imunização prime-boost e kit
WO2011041433A1 (en) * 2009-09-29 2011-04-07 The Trustees Of The University Of Pennsylvania Methods for diagnosing and treating encephalitis or epilepsy
US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
UY33821A (es) * 2010-12-22 2012-07-31 Bayer Animal Health Gmbh Respuesta inmune potenciada en la especie bovina
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
US20150031699A1 (en) 2013-07-26 2015-01-29 Boehringer Ingelheim International Gmbh Treatment of myelodysplastic syndrome
EP3110940A1 (en) 2014-02-28 2017-01-04 Bayer Animal Health GmbH Immunostimulatory plasmids
ES2749381T3 (es) * 2014-03-01 2020-03-20 Univ Texas Vectores víricos Isfahan recombinantes
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome
AU2016302436B2 (en) 2015-07-31 2022-03-03 Elanco Animal Health Gmbh Enhanced immune response in porcine species
CN105567646B (zh) * 2016-02-22 2019-01-01 浙江大学 分泌抗甘蔗花叶病毒单抗杂交瘤细胞株及其单抗应用
CN113968907B (zh) * 2020-07-22 2023-05-26 中国人民解放军军事科学院军事医学研究院 具有中和活性的抗尼帕病毒单克隆抗体及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59007A (en) * 1978-12-22 1983-11-30 Biogen Nv Recombinant dna molecules coding for polypeptides displaying hepatitis b virus antigenicity,method of their production and compositions containing the same
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5593972A (en) * 1993-01-26 1997-01-14 The Wistar Institute Genetic immunization
US7153510B1 (en) * 1995-05-04 2006-12-26 Yale University Recombinant vesiculoviruses and their uses
EP1280551B1 (en) * 2000-04-27 2007-01-10 Sanofi Pasteur Limited Vaccines against hiv infection
US20030021805A1 (en) * 2001-05-29 2003-01-30 Barber Glen N. Generation of HCV-like particles and chimeric HCV virus
US20030044386A1 (en) * 2001-07-11 2003-03-06 Barber Glen N. Recombinant VSV for the treatment of tumor cells

Similar Documents

Publication Publication Date Title
JP2006523224A5 (https=)
Kalams et al. Safety and immunogenicity of an HIV-1 gag DNA vaccine with or without IL-12 and/or IL-15 plasmid cytokine adjuvant in healthy, HIV-1 uninfected adults
Kent et al. Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus
Fuchs et al. First-in-human evaluation of the safety and immunogenicity of a recombinant vesicular stomatitis virus human immunodeficiency virus-1 gag vaccine (HVTN 090)
Earl et al. Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140
Goepfert et al. Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles
Lorin et al. A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV
Barouch et al. A human T-cell leukemia virus type 1 regulatory element enhances the immunogenicity of human immunodeficiency virus type 1 DNA vaccines in mice and nonhuman primates
Bansal et al. Multifunctional T-cell characteristics induced by a polyvalent DNA prime/protein boost human immunodeficiency virus type 1 vaccine regimen given to healthy adults are dependent on the route and dose of administration
Wu et al. Enhanced breadth of CD4 T-cell immunity by DNA prime and adenovirus boost immunization to human immunodeficiency virus Env and Gag immunogens
Mehendale et al. Safety and immunogenicity of DNA and MVA HIV-1 subtype C vaccine prime-boost regimens: a phase I randomised Trial in HIV-uninfected Indian volunteers
Nilsson et al. HIV-DNA given with or without intradermal electroporation is safe and highly immunogenic in healthy Swedish HIV-1 DNA/MVA vaccinees: a phase I randomized trial
JP2003534016A (ja) 天然ウイルス感染を模倣し、病原体に対する持続的な免疫を誘発する遺伝子ワクチン
Li et al. DNA priming increases frequency of T-cell responses to a vesicular stomatitis virus HIV vaccine with specific enhancement of CD8+ T-cell responses by interleukin-12 plasmid DNA
Voss et al. Prevention of disease induced by a partially heterologous AIDS virus in rhesus monkeys by using an adjuvanted multicomponent protein vaccine
Hartnell et al. A novel vaccine strategy employing serologically different chimpanzee adenoviral vectors for the prevention of HIV-1 and HCV coinfection
JP2006523224A (ja) 免疫原性組成物および方法
Spearman HIV vaccine development: lessons from the past and promise for the future
Ake et al. Safety and immunogenicity of PENNVAX-G DNA prime administered by Biojector 2000 or CELLECTRA electroporation device with modified vaccinia Ankara-CMDR boost
CA2419822A1 (en) Modifications of hiv env, gag, and pol enhance immunogenicity for genetic immunization
Iyer et al. DNA/MVA Vaccines for HIV/AIDS
JP2013507107A5 (https=)
Berkley et al. Scientific and policy challenges to development of an AIDS vaccine
Zhao et al. Improved protection of rhesus macaques against intrarectal simian immunodeficiency virus SIVmac251 challenge by a replication-competent Ad5hr-SIV env/rev and Ad5hr-SIV gag recombinant priming/gp120 boosting regimen
Boopathy et al. Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys