JP2006521280A5 - - Google Patents
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- Publication number
- JP2006521280A5 JP2006521280A5 JP2004551861A JP2004551861A JP2006521280A5 JP 2006521280 A5 JP2006521280 A5 JP 2006521280A5 JP 2004551861 A JP2004551861 A JP 2004551861A JP 2004551861 A JP2004551861 A JP 2004551861A JP 2006521280 A5 JP2006521280 A5 JP 2006521280A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- amino
- aryl
- alkenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CCCCCCC(C)(C)**(C)C(C)=C=C*C(*C(*I*)N*)=C Chemical compound CCCCCCC(C)(C)**(C)C(C)=C=C*C(*C(*I*)N*)=C 0.000 description 11
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42492802P | 2002-11-08 | 2002-11-08 | |
| PCT/US2003/035526 WO2004044046A2 (en) | 2002-11-08 | 2003-11-07 | Combination products with carboxylic acid derivatives that inhibit the binding of integrins to their receptors and other therapeutic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006521280A JP2006521280A (ja) | 2006-09-21 |
| JP2006521280A5 true JP2006521280A5 (https=) | 2006-12-14 |
Family
ID=32312894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004551861A Pending JP2006521280A (ja) | 2002-11-08 | 2003-11-07 | インテグリンがそのレセプターに結合するのを阻害するカルボン酸誘導体と他の治療化合物とを含む、組み合わせ生成物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20070060608A1 (https=) |
| EP (1) | EP1567505A4 (https=) |
| JP (1) | JP2006521280A (https=) |
| CN (1) | CN1735601A (https=) |
| AU (1) | AU2003291362B2 (https=) |
| BR (1) | BR0316104A (https=) |
| CA (1) | CA2513493A1 (https=) |
| CL (1) | CL2003002292A1 (https=) |
| MX (1) | MXPA05004884A (https=) |
| NO (1) | NO20052753L (https=) |
| NZ (1) | NZ539790A (https=) |
| TW (1) | TW200505861A (https=) |
| WO (1) | WO2004044046A2 (https=) |
| ZA (1) | ZA200503620B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1917244A2 (de) | 2005-08-24 | 2008-05-07 | Abbott GmbH & Co. KG | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| WO2010008719A2 (en) * | 2008-06-16 | 2010-01-21 | Schering Corporation | Oral pharmaceutical formulations of vla-4 antagonists |
| JP6669499B2 (ja) | 2013-02-15 | 2020-03-18 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物 |
| JP2016510000A (ja) | 2013-02-20 | 2016-04-04 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物およびその使用 |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| NZ719185A (en) | 2013-11-01 | 2017-11-24 | Kala Pharmaceuticals Inc | Crystalline forms of therapeutic compounds and uses thereof |
| AU2017324713B2 (en) | 2016-09-08 | 2020-08-13 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| KR20190051010A (ko) | 2016-09-08 | 2019-05-14 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정형 및 그의 용도 |
| EP3509423A4 (en) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| JP2024506858A (ja) | 2021-02-02 | 2024-02-15 | リミナル・バイオサイエンシーズ・リミテッド | Ｇｐｒ８４アンタゴニストおよびその使用 |
| TW202448457A (zh) * | 2023-05-17 | 2024-12-16 | 大陸商西藏海思科製藥有限公司 | 羧基衍生物及其在醫藥上的應用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2524709B2 (ja) * | 1985-09-26 | 1996-08-14 | 塩野義製薬株式会社 | 鎮痛消炎作用増強剤 |
| DK1176956T3 (da) * | 1999-05-07 | 2008-05-26 | Encysive Pharmaceuticals Inc | Carboxylsyrederivater, som inhiberer bindingen af integriner til deres receptorer |
| US6972296B2 (en) * | 1999-05-07 | 2005-12-06 | Encysive Pharmaceuticals Inc. | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors |
| WO2002074316A1 (en) * | 2001-03-15 | 2002-09-26 | Enteron Pharmaceuticals, Inc. | Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids |
| SI21096B (sl) * | 2001-10-09 | 2012-05-31 | Encysive Pharmaceuticals Inc | Derivati karboksilne kisline ki inhibirajo vezavo integrinov na njihove receptorje |
-
2003
- 2003-11-07 WO PCT/US2003/035526 patent/WO2004044046A2/en not_active Ceased
- 2003-11-07 TW TW092131250A patent/TW200505861A/zh unknown
- 2003-11-07 CN CNA2003801081928A patent/CN1735601A/zh active Pending
- 2003-11-07 US US10/533,693 patent/US20070060608A1/en not_active Abandoned
- 2003-11-07 MX MXPA05004884A patent/MXPA05004884A/es not_active Application Discontinuation
- 2003-11-07 AU AU2003291362A patent/AU2003291362B2/en not_active Ceased
- 2003-11-07 JP JP2004551861A patent/JP2006521280A/ja active Pending
- 2003-11-07 CA CA002513493A patent/CA2513493A1/en not_active Abandoned
- 2003-11-07 BR BR0316104-8A patent/BR0316104A/pt not_active IP Right Cessation
- 2003-11-07 NZ NZ539790A patent/NZ539790A/en unknown
- 2003-11-07 EP EP03768755A patent/EP1567505A4/en not_active Withdrawn
- 2003-11-07 CL CL200302292A patent/CL2003002292A1/es unknown
-
2005
- 2005-05-05 ZA ZA200503620A patent/ZA200503620B/en unknown
- 2005-06-07 NO NO20052753A patent/NO20052753L/no not_active Application Discontinuation
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