ZA200503620B - Combination products with carboxylic acid derivatives that inhibit the binding of integrins to theri receptors and other therapeutic compounds - Google Patents
Combination products with carboxylic acid derivatives that inhibit the binding of integrins to theri receptors and other therapeutic compounds Download PDFInfo
- Publication number
- ZA200503620B ZA200503620B ZA200503620A ZA200503620A ZA200503620B ZA 200503620 B ZA200503620 B ZA 200503620B ZA 200503620 A ZA200503620 A ZA 200503620A ZA 200503620 A ZA200503620 A ZA 200503620A ZA 200503620 B ZA200503620 B ZA 200503620B
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- ZA
- South Africa
- Prior art keywords
- alkyl
- group
- amino
- aryl
- composition
- Prior art date
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- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| US42492802P | 2002-11-08 | 2002-11-08 |
Publications (1)
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| ZA200503620B true ZA200503620B (en) | 2006-08-30 |
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Family Applications (1)
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| ZA200503620A ZA200503620B (en) | 2002-11-08 | 2005-05-05 | Combination products with carboxylic acid derivatives that inhibit the binding of integrins to theri receptors and other therapeutic compounds |
Country Status (14)
| Country | Link |
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| US (1) | US20070060608A1 (https=) |
| EP (1) | EP1567505A4 (https=) |
| JP (1) | JP2006521280A (https=) |
| CN (1) | CN1735601A (https=) |
| AU (1) | AU2003291362B2 (https=) |
| BR (1) | BR0316104A (https=) |
| CA (1) | CA2513493A1 (https=) |
| CL (1) | CL2003002292A1 (https=) |
| MX (1) | MXPA05004884A (https=) |
| NO (1) | NO20052753L (https=) |
| NZ (1) | NZ539790A (https=) |
| TW (1) | TW200505861A (https=) |
| WO (1) | WO2004044046A2 (https=) |
| ZA (1) | ZA200503620B (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1917244A2 (de) | 2005-08-24 | 2008-05-07 | Abbott GmbH & Co. KG | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
| WO2010008719A2 (en) * | 2008-06-16 | 2010-01-21 | Schering Corporation | Oral pharmaceutical formulations of vla-4 antagonists |
| EP2956138B1 (en) | 2013-02-15 | 2022-06-22 | Kala Pharmaceuticals, Inc. | Therapeutic compounds and uses thereof |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| MX368903B (es) | 2013-02-20 | 2019-10-21 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos en el tratamiento de enfermedades proliferativas. |
| US9458169B2 (en) | 2013-11-01 | 2016-10-04 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| EP3509423A4 (en) | 2016-09-08 | 2020-05-13 | Kala Pharmaceuticals, Inc. | CRYSTALLINE FORMS OF THERAPEUTIC COMPOUNDS AND USES THEREOF |
| US10336767B2 (en) | 2016-09-08 | 2019-07-02 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| AU2017324713B2 (en) | 2016-09-08 | 2020-08-13 | KALA BIO, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| US12378229B2 (en) | 2021-02-02 | 2025-08-05 | Liminal Biosciences Limited | GPR84 antagonists and uses thereof |
| WO2024235299A1 (zh) * | 2023-05-17 | 2024-11-21 | 西藏海思科制药有限公司 | 一种羧基衍生物及其在医药上的应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2524709B2 (ja) * | 1985-09-26 | 1996-08-14 | 塩野義製薬株式会社 | 鎮痛消炎作用増強剤 |
| US6972296B2 (en) * | 1999-05-07 | 2005-12-06 | Encysive Pharmaceuticals Inc. | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors |
| ATE383153T1 (de) * | 1999-05-07 | 2008-01-15 | Encysive Pharmaceuticals Inc | Carbonsäurederivate die die bindung von integrinen an ihre rezeptoren hemmen |
| AU2002254205B2 (en) * | 2001-03-15 | 2007-05-10 | Enteron Pharmaceuticals, Inc. | Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids |
| SI21096B (sl) * | 2001-10-09 | 2012-05-31 | Encysive Pharmaceuticals Inc | Derivati karboksilne kisline ki inhibirajo vezavo integrinov na njihove receptorje |
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2003
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- 2003-11-07 EP EP03768755A patent/EP1567505A4/en not_active Withdrawn
- 2003-11-07 CL CL200302292A patent/CL2003002292A1/es unknown
- 2003-11-07 TW TW092131250A patent/TW200505861A/zh unknown
- 2003-11-07 WO PCT/US2003/035526 patent/WO2004044046A2/en not_active Ceased
- 2003-11-07 BR BR0316104-8A patent/BR0316104A/pt not_active IP Right Cessation
- 2003-11-07 MX MXPA05004884A patent/MXPA05004884A/es not_active Application Discontinuation
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2005
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Also Published As
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| BR0316104A (pt) | 2005-09-27 |
| MXPA05004884A (es) | 2006-01-27 |
| NO20052753L (no) | 2005-08-08 |
| AU2003291362A1 (en) | 2004-06-03 |
| WO2004044046A3 (en) | 2004-09-30 |
| EP1567505A2 (en) | 2005-08-31 |
| WO2004044046A2 (en) | 2004-05-27 |
| NO20052753D0 (no) | 2005-06-07 |
| NZ539790A (en) | 2007-09-28 |
| CL2003002292A1 (es) | 2005-01-21 |
| US20070060608A1 (en) | 2007-03-15 |
| EP1567505A4 (en) | 2009-07-01 |
| JP2006521280A (ja) | 2006-09-21 |
| TW200505861A (en) | 2005-02-16 |
| CN1735601A (zh) | 2006-02-15 |
| AU2003291362B2 (en) | 2009-01-15 |
| CA2513493A1 (en) | 2004-05-27 |
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