JP2006520598A5 - - Google Patents
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- Publication number
- JP2006520598A5 JP2006520598A5 JP2006507065A JP2006507065A JP2006520598A5 JP 2006520598 A5 JP2006520598 A5 JP 2006520598A5 JP 2006507065 A JP2006507065 A JP 2006507065A JP 2006507065 A JP2006507065 A JP 2006507065A JP 2006520598 A5 JP2006520598 A5 JP 2006520598A5
- Authority
- JP
- Japan
- Prior art keywords
- collagen
- biocoat
- caco
- culture
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102000008186 Collagen Human genes 0.000 description 5
- 108010035532 Collagen Proteins 0.000 description 5
- 229920001436 collagen Polymers 0.000 description 5
- 238000004113 cell culture Methods 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 102100033350 ATP-dependent translocase ABCB1 Human genes 0.000 description 2
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 230000004069 differentiation Effects 0.000 description 2
- 102000013373 fibrillar collagen Human genes 0.000 description 2
- 108060002894 fibrillar collagen Proteins 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 238000013537 high throughput screening Methods 0.000 description 2
- 108010047230 Member 1 Subfamily B ATP Binding Cassette Transporter Proteins 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 239000013553 cell monolayer Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 210000001842 enterocyte Anatomy 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 239000004017 serum-free culture medium Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45523603P | 2003-03-17 | 2003-03-17 | |
| PCT/US2004/007390 WO2004083384A2 (en) | 2003-03-17 | 2004-03-11 | Accelerated culture system for intestinal epithelial cell monolayers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006520598A JP2006520598A (ja) | 2006-09-14 |
| JP2006520598A5 true JP2006520598A5 (enExample) | 2007-01-25 |
Family
ID=33029974
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006507065A Pending JP2006520598A (ja) | 2003-03-17 | 2004-03-11 | 腸上皮細胞単層のための促進された培養システム |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7300794B2 (enExample) |
| EP (1) | EP1606395A4 (enExample) |
| JP (1) | JP2006520598A (enExample) |
| CA (1) | CA2518496A1 (enExample) |
| WO (1) | WO2004083384A2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010022151A1 (en) * | 2008-08-19 | 2010-02-25 | Absorption Systems Group Llc | Methods of transporting epithelial cell monolayers |
| JP5180978B2 (ja) * | 2010-02-01 | 2013-04-10 | 花王株式会社 | 抗肥満物質のスクリーニング方法 |
| CN102676369B (zh) * | 2011-12-19 | 2013-12-25 | 河南科技大学 | 一种膳食锌生物有效性的评价模型及其建立方法 |
| CN109971699A (zh) * | 2017-12-28 | 2019-07-05 | 首都医科大学附属北京天坛医院 | 一种原代小鼠小肠上皮细胞培养液及其制备方法和应用 |
| CN111500543B (zh) * | 2020-04-16 | 2023-05-30 | 武汉普诺赛生命科技有限公司 | 一种Caco-2细胞单层膜形成培养方法 |
| CN112111445A (zh) * | 2020-09-16 | 2020-12-22 | 浙江工商大学 | 一种利用Transwell构建小鼠肠道上皮体外单层培养及表征方法 |
| CN118064371A (zh) * | 2024-04-19 | 2024-05-24 | 深圳奥礼生物科技有限公司 | 一种快速制备单层caco-2细胞渗透模型的方法 |
| CN118853540B (zh) * | 2024-09-27 | 2024-12-10 | 济南磐升生物技术有限公司 | 一种人阴道上皮模型的体外构建方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94611A (en) * | 1989-06-05 | 1994-12-29 | Organogenesis Inc | Medium for cell cultures containing insulin or growth factor similar to insulin, transferrin or iron ion, triiodothyronine or thyroxine and method of use |
-
2004
- 2004-03-11 JP JP2006507065A patent/JP2006520598A/ja active Pending
- 2004-03-11 US US10/797,952 patent/US7300794B2/en not_active Expired - Fee Related
- 2004-03-11 EP EP04719713A patent/EP1606395A4/en not_active Withdrawn
- 2004-03-11 CA CA002518496A patent/CA2518496A1/en not_active Abandoned
- 2004-03-11 WO PCT/US2004/007390 patent/WO2004083384A2/en not_active Ceased
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