|
US7569342B2
(en)
|
1997-12-10 |
2009-08-04 |
Sierra Molecular Corp. |
Removal of molecular assay interferences
|
|
EP1181054A1
(en)
|
1999-06-01 |
2002-02-27 |
Biogen, Inc. |
A blocking monoclonal antibody to vla-1 and its use for the treatment of inflammatory disorders
|
|
DE60236735D1
(de)
|
2001-04-13 |
2010-07-29 |
Biogen Idec Inc |
Antikörper gegen vla-1
|
|
US8877901B2
(en)
|
2002-12-13 |
2014-11-04 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US7591994B2
(en)
|
2002-12-13 |
2009-09-22 |
Immunomedics, Inc. |
Camptothecin-binding moiety conjugates
|
|
US20160279239A1
(en)
|
2011-05-02 |
2016-09-29 |
Immunomedics, Inc. |
Subcutaneous administration of anti-cd74 antibody for systemic lupus erythematosus and autoimmune disease
|
|
US8658773B2
(en)
|
2011-05-02 |
2014-02-25 |
Immunomedics, Inc. |
Ultrafiltration concentration of allotype selected antibodies for small-volume administration
|
|
JP5138867B2
(ja)
*
|
2002-08-01 |
2013-02-06 |
イミューノメディクス、インコーポレイテッド |
α−フェトタンパク質Immu31抗体および融合タンパク質ならびにその使用方法
|
|
US8193318B2
(en)
*
|
2002-08-14 |
2012-06-05 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8044180B2
(en)
*
|
2002-08-14 |
2011-10-25 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US20100003253A1
(en)
*
|
2002-11-08 |
2010-01-07 |
Ablynx N.V. |
Single domain antibodies directed against epidermal growth factor receptor and uses therefor
|
|
US20060034845A1
(en)
*
|
2002-11-08 |
2006-02-16 |
Karen Silence |
Single domain antibodies directed against tumor necrosis factor alpha and uses therefor
|
|
EP1558645B1
(en)
*
|
2002-11-08 |
2011-07-27 |
Ablynx N.V. |
Stabilized single domain antibodies in pharmaceutical composition adapted for inhalation
|
|
WO2004041863A2
(en)
*
|
2002-11-08 |
2004-05-21 |
Ablynx N.V. |
Single domain antibodies directed against interferon- gamma and uses therefor
|
|
US9320792B2
(en)
|
2002-11-08 |
2016-04-26 |
Ablynx N.V. |
Pulmonary administration of immunoglobulin single variable domains and constructs thereof
|
|
US20110123529A1
(en)
*
|
2002-11-08 |
2011-05-26 |
Ablynx N.V. |
Single domain antibodies directed against epidermal growth factor receptor and uses therefor
|
|
EP1900753B1
(en)
*
|
2002-11-08 |
2017-08-09 |
Ablynx N.V. |
Method of administering therapeutic polypeptides, and polypeptides therefor
|
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
CA2512729C
(en)
|
2003-01-09 |
2014-09-16 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant fc regions and methods of using same
|
|
CA2524305C
(en)
*
|
2003-05-01 |
2015-12-08 |
Imclone Systems Incorporated |
Fully human antibodies directed against the human insulin-like growth factor-1 receptor
|
|
US7172751B2
(en)
*
|
2003-06-13 |
2007-02-06 |
Immunomedics, Inc. |
D-amino acid peptides
|
|
ATE485307T1
(de)
*
|
2003-11-07 |
2010-11-15 |
Ablynx Nv |
Camelidae schwere ketten antikörper vhhs gegen epidermalen wachstumfaktor rezeptor (egfr) und ihre verwendung
|
|
US7544487B2
(en)
*
|
2004-02-13 |
2009-06-09 |
Immunomedics, Inc. |
Fusion proteins containing recombinant cytotoxic RNAses
|
|
EP1740615B1
(en)
*
|
2004-03-31 |
2014-11-05 |
Genentech, Inc. |
Humanized anti-tgf-beta antibodies
|
|
US20050227289A1
(en)
*
|
2004-04-09 |
2005-10-13 |
Reilly Edward B |
Antibodies to erythropoietin receptor and uses thereof
|
|
CA2565874C
(en)
|
2004-05-10 |
2017-10-03 |
Macrogenics, Inc. |
Humanized fc.gamma.riib-specific antibodies and methods of use thereof
|
|
AU2005335714B2
(en)
*
|
2004-11-10 |
2012-07-26 |
Macrogenics, Inc. |
Engineering Fc antibody regions to confer effector function
|
|
US20160355591A1
(en)
|
2011-05-02 |
2016-12-08 |
Immunomedics, Inc. |
Subcutaneous anti-hla-dr monoclonal antibody for treatment of hematologic malignancies
|
|
JP2006248978A
(ja)
|
2005-03-10 |
2006-09-21 |
Mebiopharm Co Ltd |
新規なリポソーム製剤
|
|
CA2612449A1
(en)
*
|
2005-06-17 |
2006-12-28 |
Imclone Systems Incorporated |
Receptor antagonists for treatment of metastatic bone cancer
|
|
PL2573114T3
(pl)
*
|
2005-08-10 |
2016-10-31 |
|
Identyfikacja i inżynieria przeciwciał z wariantami regionów FC oraz sposoby ich stosowania
|
|
AP2008004569A0
(en)
*
|
2006-02-03 |
2008-08-31 |
Imclone Systems Inc |
IGR-IR antagonists as adjuvants for treatment of prostrate cancer
|
|
EP1999470A4
(en)
*
|
2006-03-10 |
2009-08-19 |
Macrogenics Inc |
IDENTIFICATION AND GENETIC MODIFICATION OF ANTIBODIES WITH HEAVY CHAINS OF VARIANTS AND METHODS OF USE THEREOF
|
|
PL2034830T3
(pl)
*
|
2006-05-25 |
2015-04-30 |
Biogen Ma Inc |
Przeciwciało anty-VLA-1 do leczenia udaru
|
|
WO2008105886A2
(en)
|
2006-05-26 |
2008-09-04 |
Macrogenics, Inc. |
HUMANIZED FCγRIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
ES2599319T3
(es)
|
2006-06-26 |
2017-02-01 |
Macrogenics, Inc. |
Anticuerpos específicos de Fc RIIB y métodos de uso de éstos
|
|
WO2008002933A2
(en)
*
|
2006-06-26 |
2008-01-03 |
Macrogenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
|
US20080112961A1
(en)
*
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
US8652466B2
(en)
*
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
|
BRPI0813645A2
(pt)
|
2007-06-25 |
2014-12-30 |
Esbatech Alcon Biomed Res Unit |
Métodos para modificar anticorpos, e anticorpos modificados com propriedades funcionais aperfeiçoadas
|
|
WO2009123894A2
(en)
*
|
2008-04-02 |
2009-10-08 |
Macrogenics, Inc. |
Her2/neu-specific antibodies and methods of using same
|
|
ES2589912T3
(es)
*
|
2008-04-02 |
2016-11-17 |
Macrogenics, Inc. |
Anticuerpos específicos para el complejo BCR y procedimientos de uso de los mismos
|
|
JP2012504969A
(ja)
*
|
2008-10-10 |
2012-03-01 |
アナフォア インコーポレイテッド |
Trail−r1及びtrail−r2に結合するポリペプチド
|
|
CA2738243C
(en)
|
2008-10-29 |
2020-09-29 |
Wyeth Llc |
Formulations of single domain antigen binding molecules
|
|
BRPI0919879A2
(pt)
*
|
2008-10-29 |
2016-02-16 |
Wyeth Llc |
métodos para purificação de moléculas de ligação a antígeno de domínio único
|
|
ES3000111T3
(en)
|
2009-02-13 |
2025-02-27 |
Immunomedics Inc |
Intermediates for preparing conjugates with an intracellularly-cleavable linkage
|
|
US20160095939A1
(en)
|
2014-10-07 |
2016-04-07 |
Immunomedics, Inc. |
Neoadjuvant use of antibody-drug conjugates
|
|
KR101528013B1
(ko)
*
|
2009-08-31 |
2015-06-16 |
로슈 글리카트 아게 |
친화성-성숙된 인간화된 항-cea 단일클론 항체
|
|
EP2478110B1
(en)
|
2009-09-16 |
2016-01-06 |
Immunomedics, Inc. |
Class i anti-cea antibodies and uses thereof
|
|
JP5898082B2
(ja)
|
2009-10-07 |
2016-04-06 |
マクロジェニクス,インコーポレーテッド |
フコシル化程度の変更により改良されたエフェクター機能を示すFc領域含有ポリペプチドおよびその使用法
|
|
US20110086806A1
(en)
*
|
2009-10-09 |
2011-04-14 |
Anaphore, Inc. |
Polypeptides that Bind IL-23R
|
|
ES2978177T3
(es)
|
2009-12-02 |
2024-09-06 |
Immunomedics Inc |
Combinación de radio inmunoterapia y conjugados anticuerpo-fármaco para mejorar la terapia contra el cáncer
|
|
EP2542256B1
(en)
|
2010-03-04 |
2019-05-22 |
MacroGenics, Inc. |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
FR2960974B1
(fr)
|
2010-06-03 |
2016-12-30 |
Biosynex |
Procede de detection de rupture de membranes
|
|
EA201390472A1
(ru)
*
|
2010-10-29 |
2014-02-28 |
Иммьюноджен, Инк. |
Новые молекулы, связывающиеся с egfr, и их иммуноконъюгаты
|
|
RU2664698C2
(ru)
|
2011-12-13 |
2018-08-21 |
Энджинеик Молекьюлар Деливери Пти Лтд |
Полученные из бактерий интактные мини-клетки для доставки лекарственных средств к опухолям мозга
|
|
CN103215255B
(zh)
*
|
2012-01-19 |
2015-06-17 |
深圳华大基因科技有限公司 |
用于扩增免疫球蛋白轻链cdr3序列的引物集及其用途
|
|
JP6345123B2
(ja)
|
2012-02-16 |
2018-06-20 |
サンタラス, インコーポレイテッド |
抗vla1(cd49a)抗体医薬組成物
|
|
CN104379169A
(zh)
|
2012-08-14 |
2015-02-25 |
Ibc药品公司 |
用于治疗疾病的t-细胞重定向双特异性抗体
|
|
WO2017004144A1
(en)
|
2015-07-01 |
2017-01-05 |
Immunomedics, Inc. |
Antibody-sn-38 immunoconjugates with a cl2a linker
|
|
CN107753954A
(zh)
|
2012-12-13 |
2018-03-06 |
免疫医疗公司 |
功效改进且毒性降低的抗体与sn‑38的免疫缀合物的剂量
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
EP2774930A1
(en)
|
2013-03-07 |
2014-09-10 |
Aptenia S.R.L. |
Metallocene compounds and labeled molecules comprising the same for in vivo imaging.
|
|
HK1220759A1
(zh)
|
2013-03-15 |
2017-05-12 |
Hycor Biomedical Llc |
用於进行过敏症和自身免疫性疾病的诊断测定的自动化免疫分析系统
|
|
JP6447933B2
(ja)
|
2014-02-21 |
2019-01-09 |
アイビーシー ファーマスーティカルズ,インコーポレイテッド |
Trop−2発現細胞に対する免疫応答を誘発することによる疾患治療
|
|
CA2935748A1
(en)
|
2014-02-25 |
2015-09-03 |
Immunomedics, Inc. |
Humanized rfb4 anti-cd22 antibody
|
|
PL3560954T3
(pl)
|
2014-04-03 |
2021-12-13 |
Igm Biosciences, Inc. |
Zmodyfikowany łańcuch J
|
|
EP3160504B1
(en)
|
2014-06-24 |
2020-09-16 |
Immunomedics, Inc. |
Anti-histone therapy for vascular necrosis in severe glomerulonephritis
|
|
WO2016037985A1
(en)
|
2014-09-08 |
2016-03-17 |
Ruprecht-Karls-Universität Heidelberg |
Construct for the delivery of a molecule into the cytoplasm of a cell
|
|
WO2016161390A1
(en)
|
2015-04-03 |
2016-10-06 |
Eureka Therapeutics, Inc. |
Constructs targeting afp peptide/mhc complexes and uses thereof
|
|
AU2016252771B2
(en)
|
2015-04-22 |
2021-12-16 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating Trop-2-positive cancer cells
|
|
JP6980980B2
(ja)
|
2015-06-25 |
2021-12-15 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
抗hla‐drまたは抗trop‐2抗体と微小管阻害剤、parp阻害剤、ブルトンキナーゼ阻害剤またはホスホイノシチド3‐キナーゼ阻害剤との併用は癌の治療効果を有意に改善する
|
|
EP3355913B1
(en)
|
2015-09-30 |
2024-10-30 |
IGM Biosciences, Inc. |
Binding molecules with modified j-chain
|
|
EP3356401B1
(en)
|
2015-09-30 |
2020-06-24 |
IGM Biosciences, Inc. |
Binding molecules with modified j-chain
|
|
CN106810609A
(zh)
*
|
2015-11-27 |
2017-06-09 |
苏州君盟生物医药科技有限公司 |
抗pcsk9抗体及其应用
|
|
GEP20227398B
(en)
|
2016-04-15 |
2022-07-25 |
Macrogenics Inc |
Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof
|
|
US10799597B2
(en)
|
2017-04-03 |
2020-10-13 |
Immunomedics, Inc. |
Subcutaneous administration of antibody-drug conjugates for cancer therapy
|
|
MX2020000903A
(es)
|
2017-08-11 |
2020-07-22 |
Genentech Inc |
Anticuerpos anti-cd8 y usos de los mismos.
|
|
WO2020064847A1
(en)
|
2018-09-26 |
2020-04-02 |
Ascendis Pharma A/S |
Degradable hyaluronic acid hydrogels
|
|
CN110865416A
(zh)
*
|
2019-11-15 |
2020-03-06 |
南华大学 |
一种放射性胁迫下的植物生化指征测量方法
|
|
WO2022010797A2
(en)
|
2020-07-07 |
2022-01-13 |
Bionecure Therapeutics, Inc. |
Novel maytansinoids as adc payloads and their use for the treatment of cancer
|
|
US20230181471A1
(en)
|
2020-07-09 |
2023-06-15 |
Hoffmann-La Roche Inc. |
Concentrated compositions of proteins, their preparation and use thereof
|
|
WO2022239720A1
(ja)
|
2021-05-10 |
2022-11-17 |
公益財団法人川崎市産業振興財団 |
抗原への結合親和性を低減させた抗体
|
|
CN113416729B
(zh)
*
|
2021-05-18 |
2022-11-22 |
遵义医科大学附属医院 |
一种肝脏靶向调控甲胎蛋白基因的shRNA和cDNA及其应用
|
|
CN117460744A
(zh)
*
|
2021-05-31 |
2024-01-26 |
南京传奇生物科技有限公司 |
靶向afp肽/mhc复合物的抗体及其用途
|
|
WO2023016488A1
(zh)
|
2021-08-13 |
2023-02-16 |
昆山新蕴达生物科技有限公司 |
一种基于微管抑制剂的抗体偶联药物
|
|
CN116120455B
(zh)
*
|
2021-08-23 |
2023-11-07 |
东莞市朋志生物科技有限公司 |
一种抗ca15-3蛋白的重组抗体
|
|
CN117881431A
(zh)
|
2021-08-24 |
2024-04-12 |
昆山新蕴达生物科技有限公司 |
一种由可断裂连接子偶联的抗体偶联药物
|
|
WO2023056240A2
(en)
|
2021-09-28 |
2023-04-06 |
Frontaim Biomedicines, Inc. |
Multiple formats of molecular complexes
|
|
CN118401258A
(zh)
|
2021-12-09 |
2024-07-26 |
昆山新蕴达生物科技有限公司 |
一种亲和力改善的抗体-药物偶联物、其制备方法及应用
|
|
CR20250080A
(es)
|
2022-08-10 |
2025-04-10 |
Kowa Co |
Nuevo complejo de fármacos
|
|
EP4724490A2
(en)
|
2023-06-12 |
2026-04-15 |
Amgen Inc. |
Lymphotoxin beta receptor agonist binding proteins
|
|
EP4731758A2
(en)
*
|
2023-06-20 |
2026-04-29 |
The Methodist Hospital |
Antigen-specific t cell receptors and chimeric antigen receptors, and methods of use in immune signaling modulation for cancer immunotherapy
|
|
WO2025149667A1
(en)
|
2024-01-12 |
2025-07-17 |
Pheon Therapeutics Ltd |
Antibody drug conjugates and uses thereof
|