JP2006514627A - 治療薬の標的化送達のための多重特異的非共有結合複合体の使用 - Google Patents
治療薬の標的化送達のための多重特異的非共有結合複合体の使用 Download PDFInfo
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| PCT/GB2003/004994 WO2004045642A1 (en) | 2002-11-15 | 2003-11-17 | Use of multi-specific, non-covalent complexes for targeted delivery of therapeutics |
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| JP2006514627A true JP2006514627A (ja) | 2006-05-11 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JP2017520557A (ja) * | 2014-06-26 | 2017-07-27 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ヒト化抗Ｔａｕ（ｐＳ４２２）抗体脳シャトル及びその使用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7591994B2 (en) | 2002-12-13 | 2009-09-22 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| KR20060041205A (ko) * | 2003-07-01 | 2006-05-11 | 이뮤노메딕스, 인코오포레이티드 | 양특이성 항체들의 다가 담체들 |
| JP2007524412A (ja) * | 2004-01-22 | 2007-08-30 | イムノメディクス， インコーポレイテッド | 葉酸コンジュゲートおよびコンプレックス |
| US20060057062A1 (en) * | 2004-09-10 | 2006-03-16 | Trotter Dinko G | Compositions and methods useful in pretargeted imaging |
| EP3332808B1 (en) | 2005-03-03 | 2020-09-09 | Immunomedics Inc. | Humanized l243 antibodies |
| HRP20230487T1 (hr) | 2009-02-13 | 2023-07-21 | Immunomedics, Inc. | Imunokonjugati s unutarstaničnom vezom koja se može rascijepiti |
| WO2011003780A1 (en) | 2009-07-06 | 2011-01-13 | F. Hoffmann-La Roche Ag | Bi-specific digoxigenin binding antibodies |
| SG10201501803YA (en) | 2010-03-12 | 2015-05-28 | Immunogen Inc | Cd37-binding molecules and immunoconjugates thereof |
| EP2694105A4 (en) | 2011-04-01 | 2015-04-29 | Immunogen Inc | CD37 BINDING MOLECULES AND IMMUNOCONJUGATES THEREOF |
| KR102090849B1 (ko) | 2012-07-04 | 2020-03-19 | 에프. 호프만-라 로슈 아게 | 공유 결합된 항원-항체 접합체 |
| EP2869837B1 (en) | 2012-07-04 | 2016-09-14 | F. Hoffmann-La Roche AG | Anti-theophylline antibodies and methods of use |
| EP3339328A1 (en) | 2012-07-04 | 2018-06-27 | F. Hoffmann-La Roche AG | Anti-biotin antibodies and methods of use |
| CA2932958A1 (en) | 2013-12-20 | 2015-06-25 | F. Hoffmann-La Roche Ag | Humanized anti-tau(ps422) antibodies and methods of use |
| PL3089996T3 (pl) | 2014-01-03 | 2021-12-13 | F. Hoffmann-La Roche Ag | Dwuswoiste przeciwciała przeciw haptenowi/przeciw receptorowi występującemu w barierze krew-mózg, ich kompleksy i ich zastosowanie jako przenośniki wahadłowe występujące w barierze krew-mózg |
| JP6602304B2 (ja) | 2014-01-03 | 2019-11-06 | エフ．ホフマン−ラ ロシュ アーゲー | 共有結合で連結されたヘリカー−抗ヘリカー抗体コンジュゲートおよびその用途 |
| EP3089759B1 (en) | 2014-01-03 | 2018-12-05 | F. Hoffmann-La Roche AG | Covalently linked polypeptide toxin-antibody conjugates |
| WO2015148126A1 (en) * | 2014-03-12 | 2015-10-01 | Invictus Oncology Pvt. Ltd. | Targeted drug delivery through affinity based linkers |
| JP6979877B2 (ja) | 2015-06-08 | 2021-12-15 | デビオファーム インターナショナル， エス． アー． | 抗ｃｄ３７イムノコンジュゲートおよび抗ｃｄ２０抗体の組み合わせ |
| ES2809728T3 (es) | 2015-06-24 | 2021-03-05 | Hoffmann La Roche | Anticuerpos anti-tau(pS422) humanizados y procedimientos de uso |
| CA2995243A1 (en) | 2015-08-28 | 2017-03-09 | Debiopharm International, S.A. | Antibodies and assays for detection of cd37 |
| JP2020510608A (ja) | 2016-11-02 | 2020-04-09 | デビオファーム インターナショナル， エス． アー． | 抗ｃｄ３７イムノコンジュゲート療法を改善するための方法 |
| JP2021525735A (ja) | 2018-05-30 | 2021-09-27 | デビオファーム インターナショナル， エス． アー． | 抗ｃｄ３７免疫コンジュゲート投薬レジメン |
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| JP2002518460A (ja) * | 1998-06-22 | 2002-06-25 | イムノメディクス， インコーポレイテッド | プレターゲッティング診断およびプレターゲッティング治療のための二重特異性抗体の使用 |
| JP2002526457A (ja) * | 1998-09-18 | 2002-08-20 | イムノメディクス， インコーポレイテッド | 化学療法剤の標的特異的な毒性を増加させるための方法および組成物 |
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|---|---|---|---|---|
| FR2604092B1 (fr) * | 1986-09-19 | 1990-04-13 | Immunotech Sa | Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo |
| US6962702B2 (en) * | 1998-06-22 | 2005-11-08 | Immunomedics Inc. | Production and use of novel peptide-based agents for use with bi-specific antibodies |
-
2003
- 2003-11-17 US US10/714,391 patent/US20040166115A1/en not_active Abandoned
- 2003-11-17 JP JP2004552884A patent/JP2006514627A/ja active Pending
- 2003-11-17 WO PCT/GB2003/004994 patent/WO2004045642A1/en not_active Ceased
- 2003-11-17 EP EP03775576A patent/EP1560596A1/en not_active Ceased
- 2003-11-17 CA CA002505717A patent/CA2505717A1/en not_active Abandoned
- 2003-11-17 AU AU2003283599A patent/AU2003283599C1/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002518460A (ja) * | 1998-06-22 | 2002-06-25 | イムノメディクス， インコーポレイテッド | プレターゲッティング診断およびプレターゲッティング治療のための二重特異性抗体の使用 |
| JP2002526457A (ja) * | 1998-09-18 | 2002-08-20 | イムノメディクス， インコーポレイテッド | 化学療法剤の標的特異的な毒性を増加させるための方法および組成物 |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017520557A (ja) * | 2014-06-26 | 2017-07-27 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ヒト化抗Ｔａｕ（ｐＳ４２２）抗体脳シャトル及びその使用 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2505717A1 (en) | 2004-06-03 |
| US20040166115A1 (en) | 2004-08-26 |
| WO2004045642A1 (en) | 2004-06-03 |
| AU2003283599B2 (en) | 2008-11-20 |
| EP1560596A1 (en) | 2005-08-10 |
| AU2003283599C1 (en) | 2009-06-25 |
| AU2003283599A1 (en) | 2004-06-15 |
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