JP2006511473A5 - - Google Patents
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- JP2006511473A5 JP2006511473A5 JP2004537651A JP2004537651A JP2006511473A5 JP 2006511473 A5 JP2006511473 A5 JP 2006511473A5 JP 2004537651 A JP2004537651 A JP 2004537651A JP 2004537651 A JP2004537651 A JP 2004537651A JP 2006511473 A5 JP2006511473 A5 JP 2006511473A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- contrast agents
- activatable
- discloses
- prior
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/252,311 US7303741B2 (en) | 2002-09-23 | 2002-09-23 | Systems and methods for high-resolution in vivo imaging of biochemical activity in a living organism |
| PCT/US2003/025184 WO2004026344A1 (en) | 2002-09-23 | 2003-08-11 | Bifunctional contrast agent comprising a fluorescent dye and an mri contrast agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006511473A JP2006511473A (ja) | 2006-04-06 |
| JP2006511473A5 true JP2006511473A5 (https=) | 2006-09-28 |
Family
ID=31992929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004537651A Pending JP2006511473A (ja) | 2002-09-23 | 2003-08-11 | 蛍光染料及びmri造影剤を含む二元機能造影剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7303741B2 (https=) |
| EP (1) | EP1545629A1 (https=) |
| JP (1) | JP2006511473A (https=) |
| CN (1) | CN1684710A (https=) |
| AU (1) | AU2003259769A1 (https=) |
| WO (1) | WO2004026344A1 (https=) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE536993T1 (de) | 2002-01-02 | 2011-12-15 | Visen Medical Inc | Aminfunktionalisierte superparamagnetisierte nanoteilchen für die synthese von biokonjugaten |
| WO2005017539A2 (en) * | 2003-08-14 | 2005-02-24 | The General Hospital Corporation | Imaging pathology |
| US20050152842A1 (en) * | 2003-12-24 | 2005-07-14 | Chun Li | Poly (L-glutamic acid) paramagnetic material complex and use as a biodegradable MRI contrast agent |
| EP1846042A2 (en) * | 2005-01-05 | 2007-10-24 | Board of Regents, The University of Texas System | Conjugates for dual imaging and radiochemotherapy: composition, manufacturing, and applications |
| JP2008527119A (ja) | 2005-01-13 | 2008-07-24 | シンベンション アーゲー | 炭素ナノ粒子を含有する複合材料 |
| FI20055653A7 (fi) * | 2005-12-08 | 2007-06-09 | Wallac Oy | Leimausreagenssi |
| WO2007136413A2 (en) | 2005-12-22 | 2007-11-29 | Visen Medical, Inc. | Biocompatible fluorescent metal oxide nanoparticles |
| US20070148094A1 (en) * | 2005-12-22 | 2007-06-28 | Uzgiris Egidijus E | Polymeric imaging agents and medical imaging methods |
| AU2007244705A1 (en) * | 2006-04-27 | 2007-11-08 | Barnes-Jewish Hospital | Detection and imaging of target tissue |
| DE102006021317B3 (de) * | 2006-05-06 | 2007-10-11 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren und Fluoreszenzlichtmikroskop zum räumlich hochauflösenden Abbilden einer Struktur einer Probe |
| CA2692923A1 (en) * | 2006-07-03 | 2008-06-26 | Beth Israel Deaconess Medical Center, Inc. | Intraoperative imaging methods |
| US7906106B2 (en) * | 2007-06-27 | 2011-03-15 | General Electric Company | In vivo cell trafficking |
| US8021647B2 (en) | 2007-06-29 | 2011-09-20 | General Electric Company | In vivo optical imaging |
| CN102159253A (zh) | 2008-03-24 | 2011-08-17 | 得克萨斯大学体系董事会 | 心肌病的显像引导的治疗:组合物、制备和用途 |
| WO2009121055A1 (en) * | 2008-03-28 | 2009-10-01 | Georgia Tech Research Corporation | Reduced dye probes for the detection of radical oxygen species |
| US8758727B2 (en) * | 2008-03-31 | 2014-06-24 | University Of Louisville Research Foundation, Inc. | Site specific fluorescence and contrast marker for same |
| US8440167B2 (en) * | 2008-10-27 | 2013-05-14 | University Of Virginia Patent Foundation | Multimodal imaging of atherosclerotic plaque targeted to LOX-1 |
| CN102497803B (zh) * | 2009-05-05 | 2015-03-25 | 卢米托股份有限公司 | 用于散射介质中改进的扩散发光成像或者断层照相的系统、方法和发光标记物 |
| CN101554481B (zh) * | 2009-05-19 | 2011-04-13 | 泸州医学院附属医院 | 用于spect和mri的双功能显像剂及其制备方法 |
| WO2011109216A2 (en) * | 2010-03-01 | 2011-09-09 | University Of Florida Research Foundation, Inc. | Nir materials and nanomaterials for theranostic applications |
| US8834846B2 (en) | 2010-05-06 | 2014-09-16 | Bruker Biospin Corporation | Fluorescent NIRF activatable probes for disease detection |
| WO2012047841A2 (en) * | 2010-10-04 | 2012-04-12 | Nuovoprobe Ltd. | System and method for electromagnetic imaging and therapeutics using specialized nanoparticles |
| KR101352342B1 (ko) * | 2010-11-24 | 2014-02-17 | 서울대학교산학협력단 | 코어 물질과 쉘 물질 사이에 나노갭이 형성된 단일 나노입자 및 이의 제조방법 |
| CN102167813B (zh) * | 2011-01-19 | 2012-08-08 | 兰州大学 | 一种荧光示踪纳米磁共振成像造影剂 |
| EP2494936A3 (en) * | 2011-03-03 | 2012-09-19 | Imris Inc. | MR compatible optical viewing device for use in the bore of an MR magnet |
| JPWO2012128162A1 (ja) * | 2011-03-18 | 2014-07-24 | コニカミノルタ株式会社 | 画像診断用シリカナノ粒子、その製造方法、及び生体物質標識剤 |
| CN102166365B (zh) * | 2011-04-25 | 2012-10-24 | 东南大学 | 一种多模态碘油纳米乳造影剂的制备方法 |
| CN102397562B (zh) * | 2011-11-23 | 2012-11-28 | 南昌大学 | 一种由普鲁士蓝负载Gd3+的造影剂的制备方法 |
| US9492571B2 (en) * | 2012-06-01 | 2016-11-15 | University Of Massachusetts | Molecular probes for multimodality imaging and tracking of stem cells |
| US9903821B2 (en) | 2013-05-01 | 2018-02-27 | Indian Institute Of Technology Madras | Coated mesoflowers for molecular detection and smart barcode materials |
| KR101567157B1 (ko) * | 2013-12-13 | 2015-11-09 | 경북대학교 산학협력단 | Mri/fi 조영제 및 이의 제조방법 |
| US10570173B2 (en) | 2015-01-22 | 2020-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protease-activated contrast agents for in vivo imaging |
| KR102669535B1 (ko) | 2017-03-30 | 2024-05-24 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 생체 내 이미징을 위한 프로테아제 활성화 조영제 |
| CN107384385B (zh) * | 2017-07-31 | 2020-10-30 | 中山大学 | MR/FL双模态成像探针及其制备方法以及掺杂Ho碳量子点的用途 |
| WO2020127154A1 (en) * | 2018-12-18 | 2020-06-25 | Bracco Imaging Spa | Pharmaceutical compositions comprising gd-complexes and polyarylene additives |
| CN110665015A (zh) * | 2019-10-23 | 2020-01-10 | 中山大学 | 一种肿瘤微环境响应型荧光/磁共振双模态成像探针 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4899755A (en) * | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
| US5900228A (en) * | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
| US5832931A (en) * | 1996-10-30 | 1998-11-10 | Photogen, Inc. | Method for improved selectivity in photo-activation and detection of molecular diagnostic agents |
| US6083486A (en) * | 1998-05-14 | 2000-07-04 | The General Hospital Corporation | Intramolecularly-quenched near infrared fluorescent probes |
| US6592847B1 (en) | 1998-05-14 | 2003-07-15 | The General Hospital Corporation | Intramolecularly-quenched near infrared flourescent probes |
| US6217848B1 (en) | 1999-05-20 | 2001-04-17 | Mallinckrodt Inc. | Cyanine and indocyanine dye bioconjugates for biomedical applications |
| IT1318485B1 (it) * | 2000-04-21 | 2003-08-25 | Bracco Spa | Uso di derivati di acidi biliari coniugati con complessi di ionimetallici nella visualizzazione diagnostica di sistemi microvascolari |
-
2002
- 2002-09-23 US US10/252,311 patent/US7303741B2/en not_active Expired - Fee Related
-
2003
- 2003-08-11 AU AU2003259769A patent/AU2003259769A1/en not_active Abandoned
- 2003-08-11 EP EP03797836A patent/EP1545629A1/en not_active Ceased
- 2003-08-11 CN CN03822648.0A patent/CN1684710A/zh active Pending
- 2003-08-11 WO PCT/US2003/025184 patent/WO2004026344A1/en not_active Ceased
- 2003-08-11 JP JP2004537651A patent/JP2006511473A/ja active Pending
-
2007
- 2007-10-19 US US11/875,245 patent/US20080118439A1/en not_active Abandoned
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