JP2006510654A - 糖尿病を処置する方法 - Google Patents
糖尿病を処置する方法 Download PDFInfo
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- JP2006510654A JP2006510654A JP2004558236A JP2004558236A JP2006510654A JP 2006510654 A JP2006510654 A JP 2006510654A JP 2004558236 A JP2004558236 A JP 2004558236A JP 2004558236 A JP2004558236 A JP 2004558236A JP 2006510654 A JP2006510654 A JP 2006510654A
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- Prior art keywords
- alkyl
- fluorophenyl
- imidazole
- aryl
- diabetes
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43124102P | 2002-12-06 | 2002-12-06 | |
| PCT/US2003/040140 WO2004053107A2 (en) | 2002-12-06 | 2003-12-05 | Methods for treating diabetes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006510654A true JP2006510654A (ja) | 2006-03-30 |
| JP2006510654A5 JP2006510654A5 (https=) | 2007-02-01 |
Family
ID=32507688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004558236A Pending JP2006510654A (ja) | 2002-12-06 | 2003-12-05 | 糖尿病を処置する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040171659A1 (https=) |
| EP (1) | EP1583535A4 (https=) |
| JP (1) | JP2006510654A (https=) |
| AU (1) | AU2003299652A1 (https=) |
| CA (1) | CA2511763A1 (https=) |
| WO (1) | WO2004053107A2 (https=) |
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|---|---|---|---|---|
| US7765004B2 (en) * | 2005-04-28 | 2010-07-27 | Cardiac Pacemakers, Inc. | Methods and systems for managing fusion and noise in cardiac pacing response classification |
| WO2007075896A2 (en) * | 2005-12-22 | 2007-07-05 | Kemia, Inc. | Heterocyclic cytokine inhibitors |
| CA2857374A1 (en) * | 2011-09-02 | 2013-03-07 | The Trustees Of Columbia University In The City Of New York | Camkii, ip3r, calcineurin, p38 and mk2/3 inhibitors to treat metabolic disturbances of obesity |
| US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
| WO2019071147A1 (en) | 2017-10-05 | 2019-04-11 | Fulcrum Therapeutics, Inc. | INHIBITORS OF KINASE P38 REDUCING EXPRESSION OF DUX4 GENE AND DOWNSTREAM GENES FOR THE TREATMENT OF FSHD |
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| US4107288A (en) * | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| US4619652A (en) * | 1982-12-23 | 1986-10-28 | Alza Corporation | Dosage form for use in a body mounted pump |
| US5145684A (en) * | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| US6096748A (en) * | 1996-03-13 | 2000-08-01 | Smithkline Beecham Corporation | Pyrimidine compounds useful in treating cytokine mediated diseases |
| GB9713726D0 (en) * | 1997-06-30 | 1997-09-03 | Ciba Geigy Ag | Organic compounds |
| ES2221213T3 (es) * | 1997-10-20 | 2004-12-16 | F. Hoffmann-La Roche Ag | Inhibidores de kinasa biciclicos. |
| US6589954B1 (en) * | 1998-05-22 | 2003-07-08 | Scios, Inc. | Compounds and methods to treat cardiac failure and other disorders |
| US6599710B1 (en) * | 1999-03-10 | 2003-07-29 | The General Hospital Corporation | Treatment of autoimmune disease |
| JP2003500403A (ja) * | 1999-05-21 | 2003-01-07 | サイオス，インコーポレーテッド | ｐ３８キナーゼのインヒビターとしてのインドール型誘導体 |
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2003
- 2003-12-05 EP EP03799936A patent/EP1583535A4/en not_active Withdrawn
- 2003-12-05 US US10/728,665 patent/US20040171659A1/en not_active Abandoned
- 2003-12-05 AU AU2003299652A patent/AU2003299652A1/en not_active Abandoned
- 2003-12-05 WO PCT/US2003/040140 patent/WO2004053107A2/en not_active Ceased
- 2003-12-05 JP JP2004558236A patent/JP2006510654A/ja active Pending
- 2003-12-05 CA CA002511763A patent/CA2511763A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003299652A1 (en) | 2004-06-30 |
| CA2511763A1 (en) | 2004-06-24 |
| US20040171659A1 (en) | 2004-09-02 |
| EP1583535A2 (en) | 2005-10-12 |
| EP1583535A4 (en) | 2008-03-19 |
| WO2004053107A3 (en) | 2004-10-07 |
| AU2003299652A8 (en) | 2004-06-30 |
| WO2004053107A2 (en) | 2004-06-24 |
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