JP2006505307A - 設計された表面を有する移植可能な材料、および該材料を作製する方法 - Google Patents
設計された表面を有する移植可能な材料、および該材料を作製する方法 Download PDFInfo
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- JP2006505307A JP2006505307A JP2004539962A JP2004539962A JP2006505307A JP 2006505307 A JP2006505307 A JP 2006505307A JP 2004539962 A JP2004539962 A JP 2004539962A JP 2004539962 A JP2004539962 A JP 2004539962A JP 2006505307 A JP2006505307 A JP 2006505307A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/028—Other inorganic materials not covered by A61L31/022 - A61L31/026
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/024—Carbon; Graphite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0077—Special surfaces of prostheses, e.g. for improving ingrowth
- A61F2002/0086—Special surfaces of prostheses, e.g. for improving ingrowth for preferentially controlling or promoting the growth of specific types of cells or tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00598—Coating or prosthesis-covering structure made of compounds based on metal oxides or hydroxides
- A61F2310/00616—Coating made of titanium oxide or hydroxides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/24—Structurally defined web or sheet [e.g., overall dimension, etc.]
- Y10T428/24355—Continuous and nonuniform or irregular surface on layer or component [e.g., roofing, etc.]
Abstract
Description
Claims (19)
- 移植可能な生体適合性の材料であって、該材料は少なくとも1つの表面を含み、該少なくとも1つの表面上に特徴部のパターン化された配列を有し、該特徴部は、特徴部以外の該少なくとも1つの表面の領域とは異なる化学的、生理化学的および電気化学的活性の少なくとも1つを有することを特徴とする移植可能な生体適合性の材料。
- 該異なる化学的、生理化学的または電気化学的特性が、疎水性、親水性および表面エネルギーの少なくとも1つをさらに含むことを特徴とする、請求項1に記載の移植可能な生体適合性の材料。
- 該特徴部のそれぞれが、該材料の該少なくとも1つの表面上に、0μmおよび3μmの間の厚さを有する表面要素をさらに含むことを特徴とする、請求項1に記載の移植可能な生体適合性の材料。
- 該表面要素のそれぞれが、該生体適合性の材料の光化学的に変性される領域をさらに含むことを特徴とする、請求項3に記載の移植可能な生体適合性の材料。
- 該光化学的に変性される領域のそれぞれが、酸化チタンをさらに含むことを特徴とする、請求項4に記載の移植可能な生体適合性の材料。
- 該表面要素のそれぞれが、該材料の該少なくとも1つの表面上に隆起された要素をさらに含むことを特徴とする、請求項3に記載の移植可能な生体適合性の材料。
- 該隆起された要素のそれぞれが、約0.1μmおよび約3μmの間の厚さを有することを特徴とする、請求項6に記載の移植可能な生体適合性の材料。
- 該隆起された要素のそれぞれが、炭素およびニッケル−チタン合金からなる群から選択されることを特徴とする、請求項6に記載の移植可能な生体適合性の材料。
- 該特徴部のそれぞれが、内皮細胞の親和性結合のための焦点接着点を含むことを特徴とする、請求項1に記載の移植可能な生体適合性の材料。
- 該特徴部のそれぞれが、約10μmから約75μmの間の幅を有することを特徴とする、請求項1に記載の移植可能な生体適合性の材料。
- 生体適合性の材料を含む医療装置に適する移植可能な材料であって、該材料の少なくとも1つの表面は、該少なくとも1つの表面上の所定のパターンに配列される複数の親和性結合ドメインをさらに含み、該複数の親和性結合ドメインは、親和性結合ドメイン以外の該少なくとも1つの表面の区域とは異なる化学的、生理化学的または電気化学的活性を有し、該複数の親和性結合ドメインのそれぞれは、内皮細胞表面のインテグリンクラスターを結合する特異性を有し、および該少なくとも1つの表面に沿って内皮細胞の移動および増殖を促進するのに適合する結合ドメイン間の間隔を有する、移植可能な材料。
- 該異なる化学的、生理化学的または電気化学的な特性が、疎水性、親水性および表面エネルギーの少なくとも1つをさらに含むことを特徴とする、請求項11に記載の移植可能な材料。
- 親和性結合ドメインのそれぞれが、該材料の該少なくとも1つの表面上に、0μmおよび3μmの間の厚さを有する表面要素をさらに含むことを特徴とする、請求項11に記載の移植可能な材料。
- 該表面要素のそれぞれが、該生体適合性の材料の光化学的に変性される領域をさらに含むことを特徴とする、請求項13に記載の移植可能な材料。
- 該光化学的に変性される領域のそれぞれが、酸化チタンをさらに含むことを特徴とする、請求項14に記載の移植可能な材料。
- 該表面要素のそれぞれが、該材料の該少なくとも1つの表面上に隆起された要素をさらに含むことを特徴とする、請求項13に記載の移植可能な材料。
- 該隆起された要素のそれぞれが、約0.1μmおよび約3μmの間の厚さを有することを特徴とする、請求項16に記載の移植可能な材料。
- 該隆起された要素のそれぞれが、炭素およびニッケル−チタン合金からなる群から選択されることを特徴とする、請求項16に記載の移植可能な材料。
- 医療装置における使用に適する移植可能な材料を製造する方法であって:
a.生体内で組織または体液と接触することを意図される少なくとも1つの表面を有する生体適合性の材料を提供する工程と;
b.サイズおよび間隔が、該少なくとも1つの表面上に対して与えられる結合ドメインの所定の分布に相当する、開口部の画定されたパターンを有するマスクを提供する工程と;
c.該生体適合性の材料の該少なくとも1つの表面を、該マスクを通して処理する工程であって
i.該少なくとも1つの表面を光化学的に変性させるための光照射、または
ii.該少なくとも1つの表面上に対して、該少なくとも1つの表面の領域を化学的、生理化学的または電気化学的に変性させるために十分な厚さで材料を真空堆積させること
の少なくとも1つによって処理する工程と;
d.該移植可能な材料の該少なくとも1つの表面上に画定される複数の結合ドメインをもたらすために該マスクを除去する工程と
を含むことを特徴とする方法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US41403102P | 2002-09-26 | 2002-09-26 | |
PCT/US2003/030383 WO2004028347A2 (en) | 2002-09-26 | 2003-09-26 | Implantable materials having engineered surfaces and method of making same |
Publications (1)
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JP2006505307A true JP2006505307A (ja) | 2006-02-16 |
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ID=32043330
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Application Number | Title | Priority Date | Filing Date |
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JP2004539962A Pending JP2006505307A (ja) | 2002-09-26 | 2003-09-26 | 設計された表面を有する移植可能な材料、および該材料を作製する方法 |
Country Status (6)
Country | Link |
---|---|
US (6) | US8147859B2 (ja) |
EP (1) | EP1551569B1 (ja) |
JP (1) | JP2006505307A (ja) |
AU (1) | AU2003272710B2 (ja) |
CA (1) | CA2499976C (ja) |
WO (1) | WO2004028347A2 (ja) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2009542359A (ja) * | 2006-06-29 | 2009-12-03 | ボストン サイエンティフィック リミテッド | 選択的被覆部を備えた医療装置 |
JP2012509750A (ja) * | 2008-11-25 | 2012-04-26 | ザ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア | 機能性チタンインプラントおよびそれに類する再生可能材料 |
JP2014514127A (ja) * | 2011-05-13 | 2014-06-19 | パルマズ サイエンティフィック,インコーポレイテッド | システム表面およびその製造方法を有する移植用材料 |
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Citations (7)
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WO2004028347A3 (en) | 2005-02-17 |
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AU2003272710A1 (en) | 2004-04-19 |
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US10034967B2 (en) | 2018-07-31 |
US20180344904A1 (en) | 2018-12-06 |
US9399087B2 (en) | 2016-07-26 |
US20190307926A1 (en) | 2019-10-10 |
EP1551569A2 (en) | 2005-07-13 |
CA2499976A1 (en) | 2004-04-08 |
CA2499976C (en) | 2013-06-11 |
US20120135192A1 (en) | 2012-05-31 |
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