JP2006501848A5 - - Google Patents
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- Publication number
- JP2006501848A5 JP2006501848A5 JP2004543152A JP2004543152A JP2006501848A5 JP 2006501848 A5 JP2006501848 A5 JP 2006501848A5 JP 2004543152 A JP2004543152 A JP 2004543152A JP 2004543152 A JP2004543152 A JP 2004543152A JP 2006501848 A5 JP2006501848 A5 JP 2006501848A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- retinal pigment
- composition
- retinal
- pigment epithelial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims 36
- 210000004027 cell Anatomy 0.000 claims 34
- 210000001691 amnion Anatomy 0.000 claims 27
- 210000000844 retinal pigment epithelial cell Anatomy 0.000 claims 19
- 208000017442 Retinal disease Diseases 0.000 claims 14
- 210000003583 retinal pigment epithelium Anatomy 0.000 claims 12
- 239000000790 retinal pigment Substances 0.000 claims 10
- 239000003102 growth factor Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 238000011282 treatment Methods 0.000 claims 7
- 210000004379 membrane Anatomy 0.000 claims 6
- 239000012528 membrane Substances 0.000 claims 6
- 210000004748 cultured cell Anatomy 0.000 claims 5
- 102000004190 Enzymes Human genes 0.000 claims 4
- 108090000790 Enzymes Proteins 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 238000004519 manufacturing process Methods 0.000 claims 4
- 229940124597 therapeutic agent Drugs 0.000 claims 4
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 3
- 206010010356 Congenital anomaly Diseases 0.000 claims 3
- 206010038848 Retinal detachment Diseases 0.000 claims 3
- 239000013543 active substance Substances 0.000 claims 3
- 206010064930 age-related macular degeneration Diseases 0.000 claims 3
- 229910001424 calcium ion Inorganic materials 0.000 claims 3
- 238000012258 culturing Methods 0.000 claims 3
- 230000003834 intracellular effect Effects 0.000 claims 3
- 208000002780 macular degeneration Diseases 0.000 claims 3
- 210000001525 retina Anatomy 0.000 claims 3
- 230000004264 retinal detachment Effects 0.000 claims 3
- 210000000130 stem cell Anatomy 0.000 claims 3
- 208000024806 Brain atrophy Diseases 0.000 claims 2
- 102000003814 Interleukin-10 Human genes 0.000 claims 2
- 108090000174 Interleukin-10 Proteins 0.000 claims 2
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 2
- 210000004504 adult stem cell Anatomy 0.000 claims 2
- 210000002469 basement membrane Anatomy 0.000 claims 2
- 239000003795 chemical substances by application Substances 0.000 claims 2
- 210000003161 choroid Anatomy 0.000 claims 2
- 230000007812 deficiency Effects 0.000 claims 2
- 229940076144 interleukin-10 Drugs 0.000 claims 2
- 238000000608 laser ablation Methods 0.000 claims 2
- 230000001537 neural effect Effects 0.000 claims 2
- 230000002207 retinal effect Effects 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 206010003694 Atrophy Diseases 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 206010070834 Sensitisation Diseases 0.000 claims 1
- 238000001467 acupuncture Methods 0.000 claims 1
- 230000000961 alloantigen Effects 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 230000037444 atrophy Effects 0.000 claims 1
- 210000002798 bone marrow cell Anatomy 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 210000004240 ciliary body Anatomy 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 210000001671 embryonic stem cell Anatomy 0.000 claims 1
- 210000002919 epithelial cell Anatomy 0.000 claims 1
- 210000000981 epithelium Anatomy 0.000 claims 1
- 210000002950 fibroblast Anatomy 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 210000002735 iris pigment epithelial cell Anatomy 0.000 claims 1
- 238000013532 laser treatment Methods 0.000 claims 1
- 239000002609 medium Substances 0.000 claims 1
- 210000004976 peripheral blood cell Anatomy 0.000 claims 1
- 239000000049 pigment Substances 0.000 claims 1
- 210000002826 placenta Anatomy 0.000 claims 1
- 230000008313 sensitization Effects 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 210000003954 umbilical cord Anatomy 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41598602P | 2002-10-04 | 2002-10-04 | |
| PCT/US2003/031464 WO2004033635A2 (en) | 2002-10-04 | 2003-10-06 | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006501848A JP2006501848A (ja) | 2006-01-19 |
| JP2006501848A5 true JP2006501848A5 (enExample) | 2006-11-24 |
Family
ID=32093791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004543152A Pending JP2006501848A (ja) | 2002-10-04 | 2003-10-06 | 網膜色素上皮細胞の羊膜での培養及び移植 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7824671B2 (enExample) |
| EP (1) | EP1556063A2 (enExample) |
| JP (1) | JP2006501848A (enExample) |
| CN (1) | CN1720055A (enExample) |
| AU (1) | AU2003279132A1 (enExample) |
| CA (1) | CA2501226A1 (enExample) |
| WO (1) | WO2004033635A2 (enExample) |
Families Citing this family (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP2929782A1 (en) * | 2004-01-23 | 2015-10-14 | Ocata Therapeutics, Inc. | Improved modalities for the treatment of degenerative diseases of the retina |
| JP4863655B2 (ja) * | 2005-06-17 | 2012-01-25 | 国立大学法人 東京医科歯科大学 | 細胞含有シート |
| WO2007032224A1 (ja) * | 2005-09-13 | 2007-03-22 | Arblast Co., Ltd. | 培養細胞シート及びその作製方法 |
| JP5505760B2 (ja) | 2005-09-27 | 2014-05-28 | ティッシュテク・インコーポレーテッド | 羊膜調製物及び精製組成物及びその使用方法 |
| FR2892311B1 (fr) * | 2005-10-24 | 2012-09-28 | Ets Francais Du Sang | Pansement pour la cicatrisation des plaies, ulceres ou brulures des epitheliums, endotheliums ou muqueuses. |
| WO2007089277A1 (en) * | 2006-01-31 | 2007-08-09 | Regents Of The University Of Minnesota | Surgical support structure |
| US8372437B2 (en) | 2006-08-17 | 2013-02-12 | Mimedx Group, Inc. | Placental tissue grafts |
| DK2209888T3 (da) | 2007-10-12 | 2020-01-20 | Astellas Inst For Regenerative Medicine | Forbedrede fremgangsmåder til fremstilling af rpe-celler og sammensætninger af rpe-celler |
| US20100297234A1 (en) * | 2007-10-19 | 2010-11-25 | Ilene Sugino | Method of using an extracellular matrix to enhance cell transplant survival and differentiation |
| US20120219737A1 (en) | 2007-10-19 | 2012-08-30 | University Of Medicine And Dentistry Of New Jersey | Production of extracellular matrix, conditioned media and uses thereof |
| US9358320B2 (en) | 2008-04-25 | 2016-06-07 | Allosource | Multi-layer tissue patches |
| US9480549B2 (en) | 2008-04-25 | 2016-11-01 | Allosource | Multi-layer tissue patches |
| SG10201510586PA (en) | 2008-06-30 | 2016-01-28 | Mesoblast Inc | Treatment of Eye Diseases And Excessive Neovascularization Using A Combined Therapy |
| US7883496B2 (en) | 2008-07-03 | 2011-02-08 | Michael Campion | Eye coloring systems |
| EP2403438B1 (en) * | 2009-03-04 | 2021-04-21 | Peytant Solutions, Inc. | Stents modified with material comprising amnion tissue and corresponding processes |
| WO2011063005A2 (en) | 2009-11-17 | 2011-05-26 | Advanced Cell Technology, Inc. | Methods of producing human rpe cells and pharmaceutical preparations of human rpe cells |
| US9539082B2 (en) | 2009-11-24 | 2017-01-10 | Emory University | Tissue support structure |
| US20130108590A1 (en) * | 2010-05-10 | 2013-05-02 | Riken | Method for producing cell sheet |
| US9352003B1 (en) | 2010-05-14 | 2016-05-31 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US8883210B1 (en) | 2010-05-14 | 2014-11-11 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| US10130736B1 (en) | 2010-05-14 | 2018-11-20 | Musculoskeletal Transplant Foundation | Tissue-derived tissuegenic implants, and methods of fabricating and using same |
| EP3549617B1 (en) | 2010-07-12 | 2023-09-13 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| US9677042B2 (en) | 2010-10-08 | 2017-06-13 | Terumo Bct, Inc. | Customizable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
| CN102166374B (zh) * | 2010-11-03 | 2013-12-04 | 山东省眼科研究所 | 羊膜复合角膜缘干细胞膜片的制备方法 |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| WO2012149468A2 (en) | 2011-04-29 | 2012-11-01 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| RU2471458C1 (ru) * | 2011-07-26 | 2013-01-10 | Федеральное государственное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова Федерального агентства по высокотехнологичной медицинской помощи" | Способ лечения "сухой" формы возрастной макулярной дегенерации |
| CN103007355B (zh) * | 2011-09-20 | 2014-08-13 | 同济大学 | 一种水凝胶-纳米纤维膜及其制备方法和用途 |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| US9162011B2 (en) | 2011-12-19 | 2015-10-20 | Allosource | Flowable matrix compositions and methods |
| CA2882802C (en) * | 2012-08-24 | 2021-07-06 | Riken | Method for producing retinal pigment epithelial cell sheet |
| US10905800B1 (en) | 2013-01-29 | 2021-02-02 | BioDlogics, LLC | Ocular covering and method of use |
| EP2968646B1 (en) | 2013-03-13 | 2019-05-29 | AlloSource | Fascia fibrous compositions and methods for their use and manufacture |
| US20160038680A1 (en) * | 2013-03-15 | 2016-02-11 | Edwin Ryan | Subconjunctival injector and method |
| EP2970882B1 (en) | 2013-03-15 | 2018-11-28 | AlloSource | Cell repopulated collagen matrix for soft tissue repair and regeneration |
| CN103290051B (zh) * | 2013-06-05 | 2014-12-10 | 中国科学院生物物理研究所 | 一种将人类成纤维细胞转分化为视网膜色素上皮细胞的方法 |
| EP3068867B1 (en) | 2013-11-16 | 2018-04-18 | Terumo BCT, Inc. | Expanding cells in a bioreactor |
| AU2014360195B2 (en) | 2013-12-06 | 2018-02-08 | Allosource | Method of drying sheets of tissue |
| EP3081637B1 (en) * | 2013-12-11 | 2019-05-08 | Sumitomo Chemical Company, Limited | Method for manufacturing ciliary marginal zone-like structure |
| CN105814194A (zh) | 2013-12-11 | 2016-07-27 | 辉瑞有限公司 | 产生视网膜色素上皮细胞的方法 |
| CN106232800B (zh) | 2014-03-25 | 2020-07-03 | 泰尔茂比司特公司 | 介质的被动替代 |
| WO2015195508A1 (en) * | 2014-06-15 | 2015-12-23 | Amnio Technology Llc | Frozen therapeutic dose and package |
| EP3198006B1 (en) | 2014-09-26 | 2021-03-24 | Terumo BCT, Inc. | Scheduled feed |
| US10603174B2 (en) | 2015-03-24 | 2020-03-31 | Osiris Therapeutics, Inc. | Compositions comprising meniscal tissues and uses thereof |
| US10342831B2 (en) | 2015-05-20 | 2019-07-09 | Tissuetech, Inc. | Composition and methods for preventing the proliferation and epithelial-mesenchymal transition of epithelial cells |
| US10531957B2 (en) | 2015-05-21 | 2020-01-14 | Musculoskeletal Transplant Foundation | Modified demineralized cortical bone fibers |
| US10296301B2 (en) * | 2015-06-08 | 2019-05-21 | Cisco Technology, Inc. | Thing discovery and configuration for an internet of things integrated developer environment |
| WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
| CN109415696A (zh) | 2016-05-25 | 2019-03-01 | 泰尔茂比司特公司 | 细胞扩增 |
| US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
| US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
| FI3551216T3 (fi) | 2016-12-07 | 2024-10-14 | Mayo Found Medical Education & Res | Menetelmät ja materiaalit fibriinitukien käyttämiseksi verkkokalvon pigmenttiepiteelin siirroissa |
| US10772986B2 (en) | 2017-01-26 | 2020-09-15 | Allosource | Fascia fibrous compositions and methods for their use and manufacture |
| WO2018184028A2 (en) | 2017-03-31 | 2018-10-04 | Terumo Bct, Inc. | Cell expansion |
| US12234441B2 (en) | 2017-03-31 | 2025-02-25 | Terumo Bct, Inc. | Cell expansion |
| US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
| WO2018226648A1 (en) * | 2017-06-05 | 2018-12-13 | Mayo Foundation For Medical Education And Research | Methods and materials for culturing, proliferating, and differentiating stem cells |
| JP7553924B2 (ja) * | 2019-04-26 | 2024-09-19 | 国立研究開発法人理化学研究所 | 神経網膜と網膜色素上皮細胞とハイドロゲルとを含む複合体及びその製造方法 |
| JP7705950B2 (ja) | 2021-03-23 | 2025-07-10 | テルモ ビーシーティー、インコーポレーテッド | 細胞を増殖する方法 |
| US12209689B2 (en) | 2022-02-28 | 2025-01-28 | Terumo Kabushiki Kaisha | Multiple-tube pinch valve assembly |
| USD1099116S1 (en) | 2022-09-01 | 2025-10-21 | Terumo Bct, Inc. | Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device |
| WO2024167694A2 (en) * | 2023-02-06 | 2024-08-15 | Celularity Inc. | Placental extracellular matrices for ocular delivery of ophthalmic therapeutic agents |
| CN117625536B (zh) * | 2024-01-26 | 2024-04-30 | 中国人民解放军总医院第三医学中心 | 一种人视网膜色素上皮细胞的纯化、培养方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2110531B (en) * | 1981-11-05 | 1985-05-01 | East Grinstead Research Trust | Wound healing composition prepared from amnion |
| US6045791A (en) * | 1992-03-06 | 2000-04-04 | Photogenesis, Inc. | Retinal pigment epithelium transplantation |
| US6152142A (en) * | 1997-02-28 | 2000-11-28 | Tseng; Scheffer C. G. | Grafts made from amniotic membrane; methods of separating, preserving, and using such grafts in surgeries |
| US20020039788A1 (en) * | 2000-02-29 | 2002-04-04 | Isseroff Roslyn R. | Corneal epithelial graft composites |
| US7347876B2 (en) * | 2001-04-25 | 2008-03-25 | Ray Jui-Fang Tsai | Method for expansion of epithelial stem cells |
| WO2003018040A1 (en) * | 2001-08-24 | 2003-03-06 | The Schepens Eye Research Institute, Inc. | Composite graft for treatment of retinal diseases |
| WO2003084431A2 (en) * | 2002-03-29 | 2003-10-16 | Singapore Eye Research Institute | Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering |
| US20050026279A1 (en) * | 2003-04-28 | 2005-02-03 | Tseng Scheffer C.G. | Surgical grafts and methods of preparation |
-
2003
- 2003-10-06 WO PCT/US2003/031464 patent/WO2004033635A2/en not_active Ceased
- 2003-10-06 CN CNA2003801051956A patent/CN1720055A/zh active Pending
- 2003-10-06 EP EP03770640A patent/EP1556063A2/en not_active Withdrawn
- 2003-10-06 US US10/530,164 patent/US7824671B2/en not_active Expired - Fee Related
- 2003-10-06 CA CA002501226A patent/CA2501226A1/en not_active Abandoned
- 2003-10-06 JP JP2004543152A patent/JP2006501848A/ja active Pending
- 2003-10-06 AU AU2003279132A patent/AU2003279132A1/en not_active Abandoned
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