JP2006296335A - Apparatus for evaporating chemical - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a simple and readily usable apparatus for evaporating a chemical of the type which exhibits stable performances of evaporating the chemical and has a function to indicate the residual amount of the chemical. <P>SOLUTION: The apparatus for evaporating the chemical is designed to rotate a chemical carrier carrying the chemical on a sublimable material or a gel-forming body with a rotating and driving apparatus and evaporate the chemical from the chemical carrier under conditions in which centrifugal force acts. The chemical carrier is housed in each flexible bag formed of air-permeable paper or nonwoven fabric. The chemical carrier is composed so that at least a part of the chemical carrier is brought into contact with the inner surface of the flexible bag or nonwoven fabric even when the chemical carrier contracts with the passage of use. The end point of the evaporation of the chemical can be recognized by visually observing the state of the disappearing chemical carrier. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

The present invention relates to an improvement of a chemical volatilization device that rotates a chemical carrier and volatilizes the chemical by the action of centrifugal force.

Mosquito coil using thermal energy as a chemical volatilization method for volatilizing and releasing chemicals in the entire enclosed space (indoors, car interiors, outdoor sports tents, etc.) to control pests such as mosquitoes and moths In general, an electric mosquito mat and a liquid electric mosquito trap (liquid) are generally used, but a method of volatilizing and releasing the drug using wind power such as a fan at room temperature has been put into practical use. The latter method does not necessarily require an AC power supply and can be carried, and is therefore useful for carrying. The present inventors also disclosed in JP-A-2001-247406 that a cartridge for storing a drug-impregnated body is a motor. Disclosed is a method for volatilizing and releasing a drug by rotating and releasing the drug more efficiently.

However, conventional fan-type chemical volatilization devices, including those disclosed in Japanese Patent Application Laid-Open No. 2001-247406, cannot be said to be sufficiently satisfactory in the function of informing the expiration date of the cartridge containing the drug-impregnated body. For example, there is a method of using a color change by blending a dye impregnated with the amount of active ingredient into the drug impregnated body, but the end point is unclear, and the expiration date of the cartridge and the life of the dry battery are set to be the same Even with this method, it is difficult to match the dry cell performance because of its wide range.
Recently, a product using a liquid crystal display is commercially available. However, since an electric control mechanism is required, the apparatus is complicated and the cost is inevitably increased.

By the way, some proposals using a sublimable substance or a gel former as an indicator for displaying the amount of remaining medicine are known. For example, in JP-A-7-149601, a tablet in which a room temperature volatile insect repellent and a sublimation substance are combined is housed in a packaging container made of a breathable material. It is described that the remaining state can be recognized. Similarly, JP-A-63-222104 discloses a gel type insect repellent in which a room temperature volatile insect repellent and a gel former are combined.
However, these proposed insect repellents have a problem that when used by standing with a chiffon or the like, the disappearance of the sublimable substance or the gel-forming body is significantly influenced by environmental conditions such as the temperature. For this reason, as for the application to the indicator of a sublimable substance or a gel formation body, it is the present condition that the clear end-point display is not requested | required but the insecticide.
JP 2001-247406 A Japanese Patent Laid-Open No. 7-149601 JP 63-222104 A

An object of this invention is to provide the chemical | medical agent volatilization device of the type which had stable chemical | medical agent volatilization performance, and was equipped with the simple and easy-to-use chemical residual amount display function.

（式中、Ｘは水素原子又はメチル基を表す。Ｘが水素原子の時、Ｙはビニル基、１−プロペニル基、２−メチル−１−プロペニル基、２，２−ジクロロビニル基、２，２−ジフルオロビニル基又は２−クロロ−２−トリフルオロメチルビニル基を表し、Ｘがメチル基の時、Ｙはメチル基を表す。また、Ｚは水素原子、フッ素原子、メチル基、メトキシメチル基又はプロパルギル基を表す）で表されるフッ素置換ベンジルアルコールエステル化合物から選ばれた１種又は２種である（１）ないし（３）のいずれかに記載の薬剤揮散装置。 In order to solve the above problems, the present invention employs the following configuration.
(1) In a drug volatilization apparatus in which a drug carrier formed by supporting a drug on a sublimable substance or a gel-forming body is rotated by a rotation driving device, and the drug is volatilized from the drug carrier under a situation where centrifugal force acts. The drug carrier is housed in a flexible bag formed of breathable paper or non-woven fabric, and at least a part of the drug carrier is reduced even if the drug carrier shrinks over the course of use. The chemical volatilization device is configured to be in contact with the inner surface of the paper or the non-woven fabric, and to recognize the volatilization end point of the chemical by visually observing the disappearance state of the chemical carrier.
(2) The chemical volatilization device according to (1), wherein the sublimable substance is 2,4,6-triisopropyl-1,3,5-trioxane or adamantane.
(3) The chemical volatilization device according to (1), wherein the gel former includes an N-acylamino acid derivative-based gelling agent.
(4) The drug is represented by the general formula (I)

(Wherein X represents a hydrogen atom or a methyl group. When X is a hydrogen atom, Y represents a vinyl group, 1-propenyl group, 2-methyl-1-propenyl group, 2,2-dichlorovinyl group, 2, Represents a 2-difluorovinyl group or 2-chloro-2-trifluoromethylvinyl group, and when X is a methyl group, Y represents a methyl group, and Z represents a hydrogen atom, a fluorine atom, a methyl group, or a methoxymethyl group. Or a propargyl group). The chemical volatilization device according to any one of (1) to (3), which is one or two selected from fluorine-substituted benzyl alcohol ester compounds represented by:

The drug volatilization apparatus of the present invention is a type in which the drug carrier is rotated by a rotation drive device such as a motor, and the volatilization of the drug and the disappearance of the sublimable substance or gel forming body as the carrier proceed in substantially parallel. Since it has an excellent insecticidal effect and is provided with a simple and easy-to-use drug remaining amount display function, its practicality is extremely high.

（式中、Ｘは水素原子又はメチル基を表す。Ｘが水素原子の時、Ｙはビニル基、１−プロペニル基、２−メチル−１−プロペニル基、２，２−ジクロロビニル基、２，２−ジフルオロビニル基又は２−クロロ−２−トリフルオロメチルビニル基を表し、Ｘがメチル基の時、Ｙはメチル基を表す。また、Ｚは水素原子、フッ素原子、メチル基、メトキシメチル基又はプロパルギル基を表す）で表されるフッ素置換ベンジルアルコールエステル化合物から選ばれた常温揮散性殺虫成分が好適である。これらの化合物は、従来のアレスリン、フラメトリン及びプラレトリンに比べて蒸気圧が高く、蚊、ハエ、ブユ、ユスリカなどの害虫に対する殺虫効力も優れている。なお、化合物の酸成分において、不斉炭素に基づく光学異性体や幾何異性体が存在する場合、それらの各々や任意の混合物も本発明に包含されることはもちろんである。 Examples of the drug used in the present invention include an insecticidal component, acaricidal component, repellent component, antibacterial component, deodorant component, aroma component and the like having excellent volatility. Insecticidal components include empentrin and tephrametrin, especially the general formula (I)

(Wherein X represents a hydrogen atom or a methyl group. When X is a hydrogen atom, Y represents a vinyl group, 1-propenyl group, 2-methyl-1-propenyl group, 2,2-dichlorovinyl group, 2, Represents a 2-difluorovinyl group or 2-chloro-2-trifluoromethylvinyl group, and when X is a methyl group, Y represents a methyl group, and Z represents a hydrogen atom, a fluorine atom, a methyl group, or a methoxymethyl group. Or, a room temperature volatile insecticidal component selected from fluorine-substituted benzyl alcohol ester compounds represented by the formula: These compounds have a higher vapor pressure than conventional allethrin, framethrin, and praretrin, and are excellent in insecticidal activity against pests such as mosquitoes, flies, flyfish, chironomids. In addition, when the optical component and geometrical isomer based on an asymmetric carbon exist in the acid component of a compound, it is needless to say that each and arbitrary mixtures thereof are also included in the present invention.

Specific examples of the compound represented by the general formula (I) include 2,3,5,6-tetrafluorobenzyl-chrysanthemate (hereinafter referred to as Compound A), 2,3,5,6-tetrafluoro. Benzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as Compound B), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2 , 2-dichlorovinyl) cyclopropanecarboxylate (hereinafter referred to as Compound C), 4-methyl-2,3,5,6-tetrafluorobenzyl-chrysantemate (hereinafter referred to as Compound D), 4-methyl -2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as Compound E), 4-methyl-2, , 5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-difluorovinyl) cyclopropanecarboxylate (hereinafter referred to as Compound F), 4-methoxymethyl-2,3,5,6 -Tetrafluorobenzyl-chrysanthemate (hereinafter referred to as compound G), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxy Rate (hereinafter referred to as Compound H), 2,3,4,5,6-pentafluorobenzyl-2,2-dimethyl-3- (2-chloro-2-trifluoromethylvinyl) cyclopropanecarboxylate (hereinafter referred to as Compound H) 4-propargyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) Lopropanecarboxylate (hereinafter referred to as Compound J), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3-vinylcyclopropanecarboxylate (hereinafter referred to as Compound K) 2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as Compound L), or 4-methoxymethyl-2,3,5,6- Examples thereof include tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as compound M).

Examples of other drugs include repellent components such as diet, dimethyl phthalate, 2-ethyl-1,3-hexanediol, antibacterial components such as hinokitiol, tetrahydrolinalol, eugenol, citronellal, allyl isothiocyanate, citronella oil, Orange oil, lemon oil, lime oil, yuzu oil, lavender oil, peppermint oil, eucalyptus oil, jasmine oil, camellia oil, green tea essential oil, limonene, α-pinene, linalool, geraniol, phenylethyl alcohol, amylcinnamic aldehyde, cumin Aromatic components such as aldehyde and benzyl acetate, green leaf alcohol called “green fragrance”, and flavoring components containing green leaf aldehyde.

In the present invention, a sublimable substance or a gel former is used as the carrier for the drug. This is because the new knowledge of the present inventors, that is, the disappearance rate of the sublimable substance or the gel-forming body in a stationary state is largely influenced by environmental conditions and is not stable, but sublimation under the situation where centrifugal force acts. The active substance or gel former is based on the test result that disappears at a substantially constant rate with the volatilization of the drug.

Examples of sublimable substances include 2,4,6-triisopropyl-1,3,5-trioxane [trade name: Sunsaburi (manufactured by Ogawa Fragrance Co., Ltd.)], adamantane, tricyclododecane [trade name: Aisawa D (Idemitsu Oil Co., Ltd.). Chemical Co., Ltd.)], 2-hydroxycamphor (common name: borneol), 2,2-dimethyl-1,3-propanediol (common name: neopentyl glycol), among others, 2,4 , 6-Triisopropyl-1,3,5-trioxane and adamantane are easy to use.

The shape of the sublimable substance is arbitrary, but tablets formed into a plate shape, a rod shape, a disk shape, a donut shape, etc. are common. Moreover, 20-150 mg, Preferably 30-80 mg is suitable for the chemical | medical agent carrying amount with respect to a sublimable substance (usually 0.5-8g, preferably 1-4g). When the amount of the drug supported is less than 20 mg, the sustainability of the efficacy (particularly insecticidal efficacy) may be insufficient. On the other hand, the maximum amount of the supported amount is preferably 150 mg or less in consideration of the liquid absorption capacity of the carrier. .
When loading the drug, if necessary, the molded sublimation substance may be impregnated with a solvent, surfactant, dispersant, etc., or the mixture of the drug and the sublimation substance is melted and cooled. Or it can be formed into a tablet using a pressurizer.

On the other hand, examples of the gel former include those formed using a gelling agent such as an N-acylamino acid derivative gelling agent, an aluminum salt of 2-ethylhexanoic acid, 12-hydroxystearic acid, etc. From the viewpoints of properties, shape retention, and volatility of drugs, a type containing an N-acylamino acid derivative-based gelling agent is preferable.
N-acyl amino acid derivative-based gelling agents include N-acyl amino acid esters, N-acyl amino acid amides, and N-acyl amino acid amine salts. For example, N-lauroyl-L-glutamic acid-α, γ-di- n-Butylamide [manufactured by Ajinomoto Co., Inc., trade name: oil gelling agent GP-1] (hereinafter referred to as gelling agent A) is highly safe and easy to use.

As the solvent used together with the gelling agent A, paraffinic or aromatic hydrocarbons, aliphatic or aromatic esters and the like can be used. For example, Deotomisol S, Neothiozol S, Chuo Kasei Co., Ltd., Sorbet H, Nippon Petrochemical Co., Ltd., SH-NP, Nikko Petrochemical Co., Ltd., IP Solvent, Idemitsu Petrochemical Co., Ltd. -2835, a paraffinic solvent having 13 to 16 carbon atoms such as Isopar V manufactured by Exxon Chemical Co., Ltd., and lower alkyl esters such as phthalic acid, fumaric acid, maleic acid, or adipic acid.
The mixing ratio of each component in the drug carrier using the gelling agent A is suitably 0.1 to 10 parts by weight of the gelling agent A and 10 to 50 parts by weight of the solvent per 1 part by weight of the drug. The drug carrier is added with a predetermined amount of gelling agent A to the solvent, heated and dissolved at a temperature equal to or higher than the dissolution temperature (about 70 to 150 ° C.), then added with a predetermined amount of the drug and allowed to cool by standing. Easy to prepare.

In the drug carrier used in the present invention, a stabilizer, a fragrance, a colorant, an antistatic agent and the like may be appropriately blended. The addition of color is particularly preferable because it not only increases the commercial value but also makes it possible to clearly see the volatilization end point of the drug.

The present invention makes it possible to recognize the end point of volatilization of the drug, that is, the end point of use of the drug carrier, and the usage time of the rotation drive device by visually observing the disappearance state of the sublimable substance or the gel former. Since an electrical control mechanism such as a liquid crystal display is not required, it is inexpensive and easy to use, and the usage time of the rotary drive device can be notified almost accurately.

In the present invention, a substance other than the sublimable substance or the gel former can be used as a part of the carrier. Examples thereof include cellulosic carriers such as paper, pulp and viscose, synthetic resin carriers such as ethylene-vinyl acetate resin, polyester and olefin polymer, and inorganic carriers such as calcium silicate. However, these carriers are involved only in the volatilization of the drug, and the display function is of course left to the sublimable substance or the gel former.

In the present invention, the drug carrier is housed in a flexible bag formed of breathable paper or nonwoven fabric, and at least a part of the drug carrier is reduced even if the drug carrier shrinks with the progress of use. It is characterized in that it is configured to be in contact with the inner surface of paper or nonwoven fabric. In other words, the drug that has exuded on the surface of the sublimable substance or gel-forming body, which is the carrier, migrates and diffuses into the breathable paper or non-woven fabric, so that the volatilization of the drug and the disappearance of the drug carrier proceed in parallel. It is a thing.
As the material of paper or nonwoven fabric, natural paper, semi-synthetic fiber such as rayon, such as Japanese paper, pulp paper, polyolefin such as polyethylene (PE), polypropylene (PP), or drug adsorbent such as ethylene-vinyl acetate (EVA) The synthetic fibers are not limited to these.

Paper or nonwoven fabric, the basis weight is preferably about 10 to 60 g / m ^2. If the weight per unit area is too large, it becomes difficult to control the volatilization of the drug, and the flexibility is impaired, and the opacity increases and it is difficult to visually recognize the disappearance of the drug carrier from the outside.
Further, the paper or the nonwoven fabric is not limited to a single material, and for example, a blended material in which polypropylene is mixed with rayon may be used to impart sealing properties.

In the present invention, in order to obtain stable rotation of the drug carrier, the upper and lower sides of the drug carrier housed in the flexible bag are surrounded by the upper and lower parts, respectively, and the outer periphery is surrounded by a plurality of holding frames. A bearing that is enclosed and in a central position may be accommodated in a cartridge that can be fitted to the rotary shaft of the rotary drive device.
The shape and size of the cartridge can also be arbitrarily determined, and examples thereof include a disk-shaped, cage-shaped, or annular hollow structure having a rectangular cross section. In addition, the shape and number of the holding frames are not particularly limited, but in consideration of design convenience, for example, the upper and lower surfaces are plate-shaped and the periphery has a round shape, a triangular shape, or a rectangular shape. It is appropriate to provide a plurality of items.

The drug volatilization apparatus of the present invention can increase the volatilization efficiency of the drug by the centrifugal force acting on the drug carrier. For example, when accommodated in a cartridge, a fan is integrated on the inner peripheral side or the outer peripheral side. A configuration may be adopted in which the wind force is applied by a fan. The shape and size of the fan are not particularly limited, but a sirocco fan is suitable from the viewpoint of volatilization performance.
Furthermore, it is possible to employ a configuration in which a protective bar such as a slit shape or a mesh shape is attached around the cartridge so that fingers do not touch the rotating cartridge. At this time, a part of the chemical volatilization device that houses the cartridge may have the function of the protection bar. Further, before use, in order to prevent the medicine from volatilizing from the medicine carrier contained in the cartridge, a shielding member (for example, a seal tape) may be affixed to the ventilation portion of the cartridge. Usually peeled off just before use.

The specification of the motor used as the rotation driving device in the present invention is suitable for driving at DC 1.5V to 6.0V and giving a rotation speed of 200 to 2000 rpm. Further, as the power source, dry cell driving is preferable because of the simplification of the apparatus, but it can be shared with a 100V AC power source or can be configured using a solar cell. When using a 100V AC power supply, the voltage is dropped and rectified using an AC adapter, and then supplied to the motor power supply circuit. The AC adapter may be built in the chemical volatilization apparatus, but if it is integrated with the outlet plug, there is an advantage that the power cord between the plug and the chemical volatilization apparatus can be reduced in weight.

In the present invention, the disappearance rate of the sublimable substance or the gel-forming body in a situation in which the drug carrier is rotated by a rotation drive device and centrifugal force acts is much higher and more stable than the disappearance rate in the stationary state. It is something that uses that. That is, since the disappearance speed of the sublimable substance or gel former is substantially correlated with the period of use of the rotary drive device, it is possible to notify the end point of use of the chemical volatilization apparatus with the disappearance of the sublimable substance or gel former. Become. Also, change the air permeability of the paper or nonwoven fabric forming the flexible bag, or adjust the disappearance rate of the sublimable substance or gel former by changing the surface area by dividing the drug carrier into several parts, It can be adapted to various uses such as for 80 hours, 120 hours, 240 hours, 360 hours.

The chemical volatilization device of the present invention is simple and easy to operate, but of course, various functions may be added as long as it is allowed in terms of manufacturability and cost.
For example, the cycle of rotation and pause of the drug carrier may be repeated to volatilize the drug intermittently, or a pilot lamp indicating switch-on may be separately loaded.

The drug volatilization apparatus of the present invention obtained in this way rotates the drug carrier by a rotary drive device, and volatilizes the drug efficiently by the action of this centrifugal force, preferably by the double effect of this centrifugal force and wind by the fan, It has excellent insecticidal and insecticidal effects against various pests such as mosquitoes, moths, flies, chironomids, and clothing pests such as moths and cutworms indoors or outdoors. And since the replacement | exchange time of a chemical | medical agent support body and the usage time of a motor can be easily recognized just by visually observing the disappearance state of a chemical | medical agent support body, it is very useful and practical.
Furthermore, since the medicine remaining amount display function is based on the medicine carrier itself, there is an advantage that the medicine carrier can be replaced and used independently regardless of the battery remaining amount of the dry battery.

Next, the chemical volatilization device of the present invention will be described in more detail based on specific examples and test examples.

FIG. 1 is a perspective view of an example of the chemical volatilization device of the present invention in an open state, and FIG. 2 is a cross-sectional view of the state in which the cover is closed.
The drug volatilization apparatus 1 stores a drug carrier 2 in a flexible bag 3, a cartridge 4 loaded with the drug carrier 2, a sirocco fan 5 disposed inside the cartridge 4, and these are rotated and carried on the drug carrier 2. A motor 6 that volatilizes the discharged chemical, and a dry battery 7 as a power source. The cartridge 4 is an annular hollow structure having a rectangular cross section, and has three compartments for storing the drug carrier 2 (transparent plastic plate so that the upper surface can be seen), and the side surface has a width substantially the entire length. 2 mm opening slits are provided every 3 mm. When the motor 6 is rotated, centrifugal force and wind power generated by the sirocco fan 5 are generated, and the air flowing in from the upper surface intake port 8 passes through the inside of the cartridge 4 and flows out from the opening slit through the exhaust port 9. As a result, the drug exuded on the surface of the drug carrier 2 and the drug transferred and diffused from the surface to the flexible bag 3 are diffused into the air.

In this example, for 120 hours, 15 mg of compound E [4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate] The drug carrier 2 was obtained by carrying 1.0 g of sunsaburi (colored in blue) having a thickness of 7 mm and a substantially fan shape. This is stored in a flexible bag 3 made of a breathable polyethylene non-woven fabric (weight: 25 g / m ² ), and then stored in three compartments of an annular cartridge 4 having an outer diameter of 6.5 cm, an inner diameter of 4 cm, and a height of 2 cm. did. The motor 6 used was a motor with a rotational speed of 1400 rpm, and the dry battery 7 was a single 1.5 V AAA battery.

After mounting the cartridge 4 on the drug volatilization apparatus 1, the switch was turned on, and it was lowered to the waist and engaged in garden work for 6 hours. During use, it was not bothered by mosquitoes and flyfish, and a sufficient insect-repellent effect was observed. In addition, the blue sunsabble gradually decreased with the course of use, and all disappeared after about 120 hours of use. The drug volatilization apparatus 1 is very practical because it is easy to operate and has a function of displaying a remaining amount of drug.

To 4.2 g of disc-shaped adamantane (colored green) having a thickness of 8 mm and an outer diameter of 2.8 cm, compound B [2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1- Propenyl) cyclopropanecarboxylate] is a flexible bag 3 comprising a breathable nonwoven fabric (material: rayon / polypropylene = 9/1, basis weight: 40 g / m ² ) on a drug carrier 2 carrying 42 mg and 3 mg of fragrance. Wrapped. The cartridge 4 is a hollow disk having an outer diameter of 3.8 cm and a height of 1.5 cm, and has a bearing that can be fitted to the rotating shaft of the motor 6 at the lower center of the cartridge. In accordance with Example 1, the chemical volatilization apparatus 1 for 100 hours was produced.

When the chemical volatilization apparatus 1 was used at the entrance, it was effective for repelling mosquitoes and various pests for about 100 hours. After about 100 hours of use, the green adamantane disappeared and it was possible to clearly recognize the cartridge replacement time. In addition, in the drug volatilization apparatus 1 in which the drug carrier 2 is wrapped with a flexible bag 3 made of a breathable nonwoven fabric, the volatilization of the drug and the disappearance of adamantane as a carrier are more parallel than when the drug volatilization apparatus 1 is not wrapped with the nonwoven fabric. Progress was observed.

Compound M [4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate] 70 mg, dimethyl phthalate (3 g), gelling agent A (0 4 g) and a blue pigment mixture were dissolved by heating and poured into a disk-shaped container and allowed to cool. The obtained drug carrier 2 is wrapped in a flexible bag 3 made of breathable Japanese paper (material: pulp / polyethylene = 8/2, basis weight: 35 g / m ² ). Accordingly, the chemical volatilization device 1 for 200 hours was produced.

When this chemical volatilization apparatus 1 was used in a pet shed, the dog was not bothered by mosquitoes and various pests for about 200 hours. After about 200 hours of use, the blue gel formed body almost disappeared, and the indication of the cartridge replacement time was clear.

According to Example 1, various types of chemical volatilization for 240 hours provided with a fan-equipped cartridge (annular hollow structure having a rectangular cross section) loaded with a flexible bag 3 containing a drug carrier 2 and a motor driven by a dry cell A device was fabricated and a performance test was performed. In addition, the insecticidal efficacy is the initial overturning effect when the mosquito-repellent mat containing dl, d-cis / trans-allesrin (pinamin forte) is evaporated under the condition of a heating element heat sink temperature of 160 ° C. As a relative effective ratio.

The chemical volatilization apparatus of the present invention retains excellent insecticidal efficacy for a long period of 240 hours, can easily recognize the end point of the use period by the disappearance of the sublimable substance or gel former, It was also excellent.
On the other hand, as shown in Comparative Example 1, the one provided with the liquid crystal display by the electric control mechanism was accurate in displaying the end point, but the apparatus was complicated and the cost was inevitable. On the other hand, as in Comparative Example 2, the type that uses a dye linked to the remaining amount of the drug in the drug carrier and uses the color change for the end point display has a range of color tone after 240 hours and is unclear. Met.
Therefore, the usefulness of the present invention was confirmed.

The perspective view of the lid opening state of an example of the chemical volatilization apparatus of this invention is shown. Sectional drawing of the state which closed the lid | cover is shown.

Explanation of symbols

1: Drug volatilization device 2: Drug carrier 3: Flexible bag 4: Cartridge 5: Sirocco fan 6: Motor 7: Dry battery 8: Intake port 9: Exhaust port

Claims (4)

In the drug volatilization apparatus for rotating the drug carrier formed by supporting the drug on the sublimable substance or the gel forming body by a rotation driving device and volatilizing the drug from the drug carrier under a situation where centrifugal force acts, the drug The carrier is housed in a flexible bag formed of breathable paper or nonwoven fabric, and even if the drug carrier shrinks with the progress of use, at least a part of the carrier is paper or A chemical volatilization apparatus characterized by being configured to be in contact with the inner surface of a non-woven fabric and visually recognizing the disappearance state of the drug carrier to recognize the volatilization end point of the chemical. 2. The chemical volatilization device according to claim 1, wherein the sublimable substance is 2,4,6-triisopropyl-1,3,5-trioxane or adamantane. The drug volatilization apparatus according to claim 1, wherein the gel former contains an N-acylamino acid derivative-based gelling agent. The drug is represented by the general formula (I)

(Wherein X represents a hydrogen atom or a methyl group. When X is a hydrogen atom, Y represents a vinyl group, 1-propenyl group, 2-methyl-1-propenyl group, 2,2-dichlorovinyl group, 2, Represents a 2-difluorovinyl group or 2-chloro-2-trifluoromethylvinyl group, and when X is a methyl group, Y represents a methyl group, and Z represents a hydrogen atom, a fluorine atom, a methyl group, or a methoxymethyl group. The chemical volatilization device according to any one of claims 1 to 3, wherein the chemical volatilization device is one or two selected from fluorine-substituted benzyl alcohol ester compounds represented by the formula (or a propargyl group).

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