JP2012005355A - Apparatus for chemical volatilization - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an apparatus for chemical volatilization capable of preventing invasion of flying insects into a space which is the barrier space of a volatile chemical made by volatilizing a large amount of the volatile chemical around the same in a short time of ≤12 hours.SOLUTION: There is provided the apparatus for chemical volatilization which volatilizes the volatile chemical by rotating a carrier of the chemical on which the volatile chemical is carried, wherein 10-50 mg volatile chemical is brought to be carried on the chemical carrier, while ≥50% of the carried amount is volatilized within 12 hours from the initiation of use to form the barrier space of the volatile chemical around the same and the invasion of flying insects into the space is prevented by the apparatus for chemical volatilization. The chemical carrier is preferably brought to carry the volatile chemical by a lattice shaped or a net-like fiber structural body of a non-textured polyester-based fiber.

Description

The present invention relates to an improvement of a chemical volatilization apparatus that rotates a chemical carrier on which a volatile chemical is supported to volatilize the volatile chemical.

Mosquito coil that uses thermal energy as a chemical volatilization method that volatilizes and releases chemicals in closed spaces (such as indoors, cars, and outdoor sports tents) to control pests such as mosquitoes and flyfish. In general, an electric mosquito mat and a liquid electric mosquito trap (liquid) are generally used, but a method of volatilizing and releasing the drug using wind power such as a fan at room temperature has been put into practical use. The latter method does not necessarily require an AC power source and is portable, and thus is useful for portable use. The present inventors also disclosed in JP-A-2001-247406 (Patent Document 1) that a bead-shaped drug impregnation A drug volatilization method is disclosed in which a cartridge containing a body is rotated by a motor and the drug is volatilized and released efficiently by centrifugal force.

In JP 2006-25655 A (Patent Document 2), instead of the bead-shaped drug-impregnated body, a capillary tube is formed on the lower surface or both upper and lower surfaces of the ventilation layer forming a mesh shape in a three-dimensional direction. A drug volatilization apparatus using a sheet-like drug carrier provided with a drug holding layer having a gap enough to hold a drug solution depending on the phenomenon has been proposed. And in any type of patent document 1 and patent document 2, it was excellent in the practical volatilization performance and insecticidal effect of a chemical | medical agent.

By the way, it is necessary for such a chemical volatilization apparatus to support a high dose in response to a long-term use of 30 days or more. As a chemical carrier used for this, the volatility of the chemical is maintained. On the other hand, a material having a suitable drug retention was required. For example, Japanese Patent Laid-Open No. 2001-200209 (Patent Document 3) is made of a carrier made of twisted yarns, and a net having a mesh size in the range of 6 to 100 mesh, stretched over a frame, and the two nets. It is said that an effective amount of drug volatilization can be secured for a practical number of days by proposing a drug holder formed by juxtaposing the above and using it.

However, in the drug carrier of the conventional drug volatilization apparatus, including JP 2001-200209A (Patent Document 3), as a result of placing importance on the retention of the drug, the volatilization amount of the drug per unit time is not small. It was thought that it was technically limited to desire a significant increase in effectiveness at the initial stage of use. Thus, in a chemical volatilization device using wind power such as a fan, there is still no product based on the technical idea of vaporizing a high drug amount in a short time.

JP 2001-247406 A JP 2006-25655 A Japanese Patent Laid-Open No. 2001-200299

The present invention is a chemical volatilization device intended for short-time use within 12 hours, volatilizing a high-dose volatile chemical in a short time to form a barrier space for the volatile chemical around it, and An object of the present invention is to provide a chemical volatilization device that can prevent entry into this space.

The present invention has been found that the following constitution has an excellent effect for achieving the above-mentioned object.
(1) In a drug volatilization apparatus for rotating a drug carrier carrying a volatile drug and volatilizing the volatile drug, 10 to 50 mg of the volatile drug is carried on the drug carrier and 12 hours from the start of use. The chemical volatilization apparatus is configured to volatilize 50% or more of the supported amount within the inner space to form a barrier space for the volatile chemical around it to prevent the flying pests from entering the space.
(2) The drug volatilization apparatus according to (1), wherein the drug carrier is a polyester fiber lattice-like or net-like fiber structure that is not textured and carries the volatile drug.
(3) The chemical volatilization apparatus according to (2), wherein the polyester fiber has a wire diameter of 30 to 300 μm and a mesh number of 50 to 300 mesh.
(4) The volatile drug is a pyrethroid insecticide component, and the vapor pressure at 30 ° C. is 2 × 10 ⁻⁴ to 1 × 10 ⁻² mmHg, according to any one of (1) to (3) Chemical volatilization device.
(5) The drug volatilization apparatus according to any one of (1) to (4), wherein the drug carrier is housed in a frame, and the drug carrier is installed in a drug cartridge and rotated.

The chemical volatilization device of the present invention is a chemical volatilization device intended for short-term use within 12 hours, and volatilizes a high-dose volatile chemical in a short time to form a barrier space for the volatile chemical around it. Because it can prevent the flying pests from entering this space, its practicality is extremely high.

Examples of the volatile chemicals used in the present invention include insecticidal components, repellent components, antibacterial components, insect repellents and the like that are excellent in volatile properties. Insecticidal ingredients include empentrin and general formula (I)
(Wherein X represents a hydrogen atom or a methyl group. When X is a hydrogen atom, Y represents a vinyl group, 1-propenyl group, 2-methyl-1-propenyl group, 2,2-dichlorovinyl group, 2, Represents a 2-difluorovinyl group or 2-chloro-2-trifluoromethylvinyl group, and when X is a methyl group, Y represents a methyl group, and Z represents a hydrogen atom, a fluorine atom, a methyl group, or a methoxymethyl group. Or a room temperature volatile pyrethroid insecticidal component selected from fluorine-substituted benzyl alcohol ester compounds represented by the formula (or a propargyl group). These compounds have a vapor pressure of 2 × 10 ⁻⁴ to 1 × 10 ⁻² mmHg at 30 ° C., which is higher than that of conventional allethrin and praretrin, such as mosquitoes, flies, flyfish, chironomids, etc. It has excellent insecticidal activity against pests. In addition, when the optical component and geometrical isomer based on an asymmetric carbon exist in the acid component of a compound, it is needless to say that each and arbitrary mixtures thereof are also included in the present invention.

Specific examples of the compound represented by the general formula (I) include 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-dichlorovinyl) cyclopropanecarboxylate (hereinafter, 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as profluthrin), 4 -Methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as metfurthrin), 2,3,5,6-tetra Fluorobenzyl-chrysanthemate (hereinafter referred to as Compound A), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1- (Lopenyl) cyclopropanecarboxylate (hereinafter referred to as Compound B), 4-methyl-2,3,5,6-tetrafluorobenzyl-chrysantemate (hereinafter referred to as Compound C), 4-methyl-2,3 , 5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-difluorovinyl) cyclopropanecarboxylate (hereinafter referred to as Compound D), 4-methoxymethyl-2,3,5,6 -Tetrafluorobenzyl-chrysanthemate (hereinafter referred to as compound E), 2,3,4,5,6-pentafluorobenzyl-2,2-dimethyl-3- (2-chloro-2-trifluoromethylvinyl) ) Cyclopropanecarboxylate (hereinafter referred to as Compound F), 4-propargyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3 (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as Compound G), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3-vinylcyclopropanecarboxylate (hereinafter referred to as Compound G) Compound H), 2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as Compound I), or 4-methoxymethyl-2,3 , 5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (hereinafter referred to as Compound J).
Among the above compounds, empentrin, transfluthrin, profluthrin and metfurthrin are preferable in terms of performance.

Other volatile agents include, for example, repellent components such as diet, dimethyl phthalate, 2-ethyl-1,3-hexanediol, antibacterial components such as hinokitiol, tetrahydrolinalol, eugenol, allyl isothiocyanate, citronella oil, orange oil , Lemon oil, lime oil, yuzu oil, lavender oil, peppermint oil, eucalyptus oil, jasmine oil, coconut oil, green tea essential oil, limonene, α-pinene, citronellal, terpineol, linalool, geraniol, phenylethyl alcohol, amylcinnamic aldehyde And insect repellents such as cuminaldehyde and benzyl acetate.
In addition to the above components, a deodorant component, an aromatic component, for example, a green leaf alcohol called “green fragrance” or a flavor component containing green leaf aldehyde may be appropriately blended.

The present invention maintains a necessary amount of drug supported as a carrier for a drug carrier applied to a drug volatilization apparatus, despite the fact that a plastic fiber structure with poor drug adsorption is used. It has the feature that the volatilization amount has been remarkably increased.
Examples of the plastic fiber include polyester (polyethylene terephthalate, polybutylene terephthalate, etc.), polyamide, acrylic fiber, and the like. If these are the main components, a blended product with polyethylene, polypropylene, rayon, etc. may be used.
Especially, the polyester-type fiber structure which is not textured is suitable. Here, the textured yarn refers to a yarn that has been processed into curls, crimps, loops, and the like by performing steps such as twisting, sagging, and heat treatment.
In the present invention, it is preferable that polyester fibers not subjected to such textured processing are formed in a lattice shape or a net shape. From the performance test results, the wire diameter is 30 to 300 μm and the number of meshes is 50. It has been found that ~ 300 mesh is preferred.

Since the use of the present invention is mainly for outdoor use within 12 hours, it is preferable to reduce the size of the carrier of the drug carrier. For this reason, it is good to design so that the volatilization area of 1 sheet shall be about 15-50 cm < ² >, and this fiber structure may be overlapped and used as long as there is no problem in air permeability.

In the present invention, 10 to 50 mg of the volatile agent is supported on the entire carrier. If necessary, a solvent, a stabilizer, a volatilization modifier, a surfactant, a colorant, and the like may be appropriately blended together with the volatile agent. it can. Examples of the solvent include hydrocarbon solvents such as n-paraffin and isoparaffin, glycol solvents such as propylene glycol, 1,3-butylene glycol and dipropylene glycol, alcohol solvents, ketone solvents and ester solvents. Examples of the stabilizer include, but are not limited to, BHT and BHA. Butyl stearate and isopropyl myristate may show the action as volatilization regulators in the present invention, and the addition of color not only enhances the commercial value but also makes it possible to clearly see the volatilization end point of the volatilizing agent. Can also be used.
In preparing the drug carrier, the loading method is not limited at all, and a known conventional technique such as a dispensing method, an impregnation method, a spray method, or the like may be appropriately employed.

The drug volatilization apparatus of the present invention employs a method of rotating the drug carrier in order to increase the diffusibility of the volatile drug. As a specific form, for example, the drug carrier is housed in a frame, A type that can be installed in a medicine cartridge and rotated. In this case, the annular drug cartridge has a bearing portion at the center thereof, which can be fitted to the rotation shaft of the rotation drive device (motor).
As a specification of the motor, a motor that gives a rotational speed of 500 to 3000 rpm with DC 1.5V to 6.0V drive is appropriate. Increasing the rotational speed can increase the volatilization amount of the volatile drug, but the volatile chemical may be scattered, so the optimum rotational speed needs to be determined after various studies.

The method of installing the drug carrier on the drug cartridge is also arbitrary. For example, a fixed part of the drug carrier may be provided on the outer periphery of the annular drug cartridge so as to correspond to part or all of the circumference thereof, and the drug carrier may be fitted together with the frame, or A configuration may be adopted in which two or more such fixed portions are installed facing each other in the vicinity of the bearing portion.
In addition, a plurality of blades can be installed inside the fixed part of the drug carrier, and the volatilization performance of the volatile drug can be further improved by applying an air volume by a fan in addition to centrifugal force.

The chemical volatilization apparatus of the present invention is provided with an intake port and an exhaust port, and a pilot lamp or the like that indicates switch-on may be separately loaded. However, since it is used for a short time, a simple structure is practical, and it is convenient that the drug carrier can be replaced every time it is used.

The thus obtained chemical volatilization apparatus of the present invention volatilizes a high-dose volatile chemical within a short period of time within 12 hours to form a volatile chemical barrier space around it, and the flying pests enter this space. The purpose is to prevent intrusion. Further, since 50% or more of the supported amount is volatilized within 12 hours from the start of use, the remaining amount after use is very small, and the utility value is high from the viewpoint of resource saving.
Pests targeted by the chemical volatilization device of the present invention are mainly mosquitoes, moths, flies, fly flies, chironomids, etc., but of course, they may be used indoors. It also has excellent effects against clothing pests such as cutworms and various pests such as cockroaches, ants, red elephants, and beetles.

Next, the chemical volatilization device of the present invention will be described in more detail based on specific examples and test examples, but the present invention is not limited to these.

A polyester fiber having a wire diameter of 50 μm and not textured was lace-knitted into a lattice (mesh number: 80 mesh). This 4 × 10 cm was folded in half to produce a 4 × 5 cm double-laminated fiber structure, and 10 mg of metfurthrin was supported thereon to prepare a drug carrier used in the present invention, which was then stored in a frame.
The drug carrier was fitted into the fixed part (two locations facing each other) of the drug carrier installed in the vicinity of the bearing part of the drug cartridge, and the drug volatilization apparatus having a metfurthrin loading of 20 mg was obtained.

When this chemical volatilization apparatus was rotated at 1600 rpm and used outdoors, the average volatilization amount per hour of metofluthrin was 1.2 mg, and the remaining amount after 12 hours was about 30%. During this time, it was confirmed that the chemical volatilization device formed a barrier space for methfluthrin around it and prevented the flying pests from entering this space without being bothered by mosquitoes, moths and chironomid pests. It was.

According to Example 1, various chemical volatilization apparatuses shown in Table 1 were prepared and performance tests were performed. The results are shown in Table 2. Incidentally, insecticidal efficacy testing examines the KT ₅₀ value and lethality against Culex adults in a practical room between 6 mats to 4 hours after use, the comparative example, the wind from the axial fan cellulose beads containing Transfluthrin The type that hits was used. Moreover, the rotation speed of the fan was all 1500 rpm.

As a result of the test, the chemical volatilization device of the present invention volatilizes a high-dose volatile chemical in a short time within 12 hours, and showed a remarkably high insecticidal effect as compared with conventional preparations intended for long-term use. . Therefore, it was recognized that a barrier space for the volatile drug could be formed around the space to prevent flying insects from entering the space. From the comparison between Example 1 and Example 4, as the carrier of the drug carrier used in the present invention, the fiber structure that is not textured is superior in volatilization performance than the textured product, and after use. The remaining amount was small and it was preferable from the viewpoint of resource saving.
On the other hand, as in Comparative Example 1, the type in which the wind was applied to the cellulosic bead drug impregnated body with an axial fan had low insecticidal efficacy, and a considerable amount of insecticidal components remained after use. Further, as in Comparative Example 2, in the case of a conventional preparation for a long period of time, as a fiber sheet type carrier, a textured product such as a twisted yarn must be employed in consideration of drug retention, and the initial use It was not possible to increase the volatilization amount.

The chemical volatilization apparatus of the present invention can be put into practical use not only in the pest control field but also in a field where chemicals are volatilized, such as the aroma and deodorization fields.

Claims (5)

In a drug volatilization apparatus for rotating a drug carrier carrying a volatile drug and volatilizing the volatile drug, the drug carrier carries 10 to 50 mg of the volatile drug and is supported within 12 hours from the start of use. A chemical volatilization device characterized in that 50% or more of the amount is volatilized to form a barrier space for the volatile chemical around it to prevent flying insects from entering the space. 2. The drug volatilization apparatus according to claim 1, wherein the drug carrier is a polyester-based fiber lattice or net-like fiber structure that is not textured and carries the volatile drug. The drug volatilization device according to claim 2, wherein the polyester fiber has a wire diameter of 30 to 300 µm and a mesh number of 50 to 300 mesh. The said volatile chemical | medical agent is a pyrethroid type insecticide component, The vapor pressure in 30 degreeC is ² * 10 ^{< -4} > ^-1 * 10 ^<-2 > mmHg, The any one of Claim 1 thru | or 3 characterized by the above-mentioned. Chemical volatilization device. The drug volatilization apparatus according to any one of claims 1 to 4, wherein the drug carrier is housed in a frame, and is configured to be rotated by being installed in a drug cartridge.