JP2004222725A - Device for volatilizing agrochemical - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a device for volatilizing agrochemicals by volatilizing the agrochemicals at room temperature under applying centrifugal force to impregnated bodies impregnated with the agrochemicals and packed in a cartridge. <P>SOLUTION: The cartridge 2 having an air-permeating part on its side face is filled with granular or almost granular bodies 1 impregnated with agrochemicals and has a rotating mechanism for rotating to act the centrifugal force on the impregnated bodies so that the impregnated agrochemicals are volatilized. Thereby, without fear of burn, the device volatilizes almost constant amounts of the agrochemicals stably for a long term and is usable in indoor and outdoor wide range areas. <P>COPYRIGHT: (C)2004,JPO&NCIPI

Description

  The present invention relates to a drug volatilization device that volatilizes a drug at room temperature by applying centrifugal force to a granular or substantially granular drug impregnated body accommodated in a replaceable cartridge and utilizing wind force generated at this time. . More specifically, in the present invention, for example, the cartridge is attached to an air outflow side and / or an air inflow side of a sirocco fan, and a centrifugal force is applied to the drug impregnated body by rotating the cartridge with a motor. The present invention relates to a chemical volatilization device that can continuously volatilize a chemical from an impregnated body at a constant volatilization rate for a long time.

In order to remove pests such as mosquitoes and moths, thermal energy was used as a chemical volatilization device that volatilizes and releases chemicals in the entire enclosed space (for example, indoors of buildings, cars, and outdoor sports tents). Mosquito coils, electric mosquito mats, and liquid electric mosquito traps (liquids) are common, but attempts have been made to volatilize and release chemicals using wind power such as fans at room temperature.
A chemical volatilization device that uses electricity from a fire or a power outlet may be difficult to use in terms of ensuring safety and power. For example, when used in a tent, it is preferable to use a method of volatilizing and releasing the drug at room temperature. In this case, if wind power such as a fan is used for volatilization of the drug, the drug (or drug impregnation) is used as it is. Compared with the case of leaving the body), the volatilization efficiency of the drug can be greatly increased.

Conventionally, many methods have been proposed as a device for volatilizing and releasing a drug at room temperature. For example, Japanese Utility Model Application Laid-Open No. 61-182273 discloses an instrument configured to install an impregnated body that retains a drug and has an appropriate air permeability around a fan, and to apply air from the fan to the impregnated body. Yes. Japanese Patent Application Laid-Open No. 10-191862 discloses that a granular drug impregnated body is placed in an impregnated container, and air is blown from the fan to stir the chemical impregnated body with wind force while volatilizing the drug. An instrument is disclosed.
Furthermore, JP-A-5-68459 discloses a diffusion device for a volatile drug that diffuses the volatile drug in the air by rotating a diffusion material holding the volatile drug.
Japanese Utility Model Sho 61-182273 JP-A-5-68459 JP-A-10-191862

However, in the instrument of Japanese Utility Model Laid-Open No. 61-182273 and the instrument used in the method of Japanese Patent Laid-Open No. 10-191862, the drug impregnated body is stored in a stationary storage container. In the device disclosed in Japanese Patent Application Laid-Open No. 10-191862, attempts have been made to apply the wind from the fan to the granular material which is a drug-impregnated body and stir the granular material by wind force. It is difficult to sufficiently stir the entire granular material. Therefore, in the device disclosed in Japanese Patent Laid-Open No. 10-191862, it is difficult to volatilize the drug at a constant volatilization amount over a long period from the granular material which is the drug impregnated body, and it is inevitable that the volatilization drug amount decreases with time. .
On the other hand, in the instrument disclosed in Japanese Patent Application Laid-Open No. 5-68459, a diffusion material formed by encapsulating a volatile drug in a bag or container having a membrane portion made of a gas permeable film or a bag or container having a microporous hole. Therefore, it is difficult to efficiently volatilize the drug from the entire volatile drug, and it is inevitable that the amount of the volatile drug decreases with time. Therefore, it is difficult to maintain a stable volatilization amount for a long period of 10 days or longer with this device.

  The present invention is for solving the problems of the prior art, and the object of the present invention is that it can be applied in the field and can stably volatilize a substantially constant amount of drug over a long period of time. An object of the present invention is to provide a drug volatilization device that has many advantages such as high insecticidal efficacy, high safety, and good usability.

As a result of intensive studies to solve the problems of the prior art, the present inventors have found that volatilization is stable over a long period of time by applying centrifugal force to the granular or substantially granular drug impregnated body in volatilizing the drug. It has been found that performance can be achieved, and the present invention has been completed.
That is, the drug volatilization device of the present invention accommodates a granular or substantially granular drug impregnated body inside, a cartridge having a vent on the side surface, and volatilizes the drug in the drug impregnated body based on centrifugal force. Therefore, it is a basic requirement that the device is a chemical volatilization device provided with a rotation mechanism for the cartridge [hereinafter referred to as i)].
The devices of the following invention are particularly preferred.
ii) The drug volatilization device according to i), wherein the drug impregnated body is filled in the cartridge with a porosity of 20% to 70%.
iii) A device for volatilizing chemicals according to i), wherein a sirocco fan (many blades for blowing air) is attached to the air outflow side and / or the air inflow side of the cartridge.
iv) The chemical volatilization device according to iii), wherein the cartridge has an annular shape and is mounted on the air outflow side of the sirocco fan.
v) The chemical volatilization device according to iii), wherein the cartridge has a disk shape and is mounted on the air inflow side of the sirocco fan.
vi) The drug is selected from the following groups: 2,3,5,6-tetrafluorobenzyl-chrysantemate (Compound A), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- ( 1-propenyl) cyclopropanecarboxylate (Compound B), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-dichlorovinyl) cyclopropanecarboxylate (Compound C), 4-methyl-2,3,5,6-tetrafluorobenzyl-chrysanthemate (Compound D), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1 -Propenyl) cyclopropanecarboxylate (compound E), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-difluorobi Le) cyclopropanecarboxylate (Compound F), 4-
Methoxymethyl-2,3,5,6-tetrafluorobenzyl-chrysanthemate (Compound G), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1 -Propenyl) cyclopropanecarboxylate (compound H), 2,3,4,5,6-pentafluorobenzyl-2,2-dimethyl-3- (2-chloro-2-trifluoromethylvinyl) cyclopropanecarboxylate (compound I), 4-propargyl-2,3,5,6-tetrafluorobenzyl-3- (1-propenyl) -2,2-dimethylcyclopropanecarboxylate (Compound J), 4-methoxymethyl-2,3 5,6-Tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (Compound K) and 4-propyl Parugiru 2,3,5,6-tetrafluoro-benzyl-2
, 2,3,3-tetramethylcyclopropanecarboxylate (compound L), i) a chemical volatilization device.
vii) The drug volatilization device according to i), wherein the granular or substantially granular drug-impregnated body comprises at least one selected from paper, pulp, cellulosic carrier and synthetic resin carrier.

The chemical volatilization device of the present invention is a system in which a centrifugal force is applied to a granular or substantially granular chemical impregnated body without heating, and the chemical is volatilized and released by the generated wind force. It is possible to stably volatilize an almost constant amount of drug over a period of time, and has an excellent insecticidal effect that has never been seen before, and also has excellent safety, usability, etc., sanitary pests such as mosquitoes and flies, It is extremely useful for controlling unpleasant pests such as blackfish, chironomid, moth, moth, and cutworm, especially mosquitoes.
Moreover, since it can be designed to be used in a compact and lightweight state that operates with dry batteries, it can be applied both indoors and outdoors, for example, indoors in a travel destination or in a tent in a camp. Very useful for controlling sanitary and unpleasant pests.
Furthermore, since different cartridges containing various different drug impregnation bodies can be replaced and used according to the purpose, it is possible to deal with various types of harmful insects with a single drug volatilization device, and the application range is wide. .
Specific effects based on the centrifugal force are as follows.
1) The granular or substantially granular drug-impregnated body is preliminarily filled in a suitable state (for example, a state close to closest packing), but since the individual particles are not fixed, impact is applied to the cartridge. When the cartridge is added or the cartridge is moved, the filling state of the drug-impregnated body changes because individual grains move. However, when a centrifugal force acts on the drug-impregnated body in use, the granular material is pressed in a predetermined direction by the centrifugal force, and an initial suitable filling state or a filling state close thereto is automatically reproduced.
2) When the action of the centrifugal force on the cartridge is released, each granular or substantially granular drug impregnated body in the cartridge can move freely to some extent, and its position is changed by rotation or movement. That is, with the action and release of the centrifugal force on the cartridge, the granular drug-impregnated body moves individually and exhibits the same effect as the case where it is stirred as a whole.
3) When a centrifugal force is applied to a granular or substantially granular drug-impregnated body, if the drug-impregnated body has a certain degree of flexibility, the drug-impregnated body is pressed and contracted to release the centrifugal force. Then, the drug impregnated body returns to its original size even when expanded. Therefore, the drug impregnated body repeatedly contracts and expands by repeatedly rotating (using) the cartridge and stopping (not using) the cartridge. This pump action also pushes the drug inside the drug impregnated body to the surface. As a result, the drug is effectively used.
4) Even when the granular or substantially granular drug-impregnated body is not very flexible, if a centrifugal force is applied to the drug-impregnated body, the drug inside the drug-impregnated body is pushed out to the surface by the centrifugal force, and Since it is conveyed by the wind force generated when the centrifugal force is applied, the drug inside the drug impregnated body can be used effectively.

In the medicine volatilization device of the present invention, a rotation mechanism for the cartridge is provided, and the centrifugal force is applied to the medicine-impregnated body stored in the cartridge based on the rotation. The size is appropriately selected in consideration of various conditions such as the size and shape of the cartridge and the drug-impregnated body, the type of the drug, and the volatilization amount. For example, the magnitude of the centrifugal force is 1/1000 to 100 times the gravity acceleration (9.8 × 10 ² cm / s ² ), specifically 9.8 × 10 ⁻¹ cm / s ^{2 to} 9.8. It may be x10 ⁴ cm / s ² .
The drug impregnated body may be filled in the cartridge at a porosity of 20% to 70%, preferably 25% to 65%, particularly preferably 30% to 60%. When the porosity is less than 20%, the flow of the air flow becomes worse, so a sufficient amount of chemical volatilization cannot be ensured. On the contrary, when the porosity exceeds 70%, the air flow contacts the drug-impregnated body. Since the time to do is shortened, sufficient chemical volatilization amount cannot be secured. Therefore, the porosity is preferably selected within the above range.
By rotating the cartridge containing the drug-impregnated body, centrifugal force acts on the drug-impregnated body, and wind force generated at this time can be used. As a driving source of the rotation mechanism for the cartridge, a motor is usually adopted.
The motor can be driven by either an AC power source or a dry battery. For example, a single battery having a voltage of 1.5 V and capable of rotating at a rotational speed of 100 to 2000 rpm for 300 hours or more is suitable.

When a sirocco fan is mounted on the air outflow side and / or the air inflow side of the cartridge, centrifugal force acts on the drug impregnated body, and wind generated by the sirocco fan on the drug impregnated body (air flow flowing out of the sirocco fan) And / or air flow flowing into the sirocco fan), the volatilization efficiency of the drug can be increased. The cartridge may be mounted only on the air outflow side of the sirocco fan or only on the air inflow side, or may be mounted on both the air outflow side and the air inflow side of the sirocco fan. The number of cartridges attached to the sirocco fan may be one or more. For example, a plurality of cartridges can be appropriately distributed and attached to the air outflow side or the air inflow side of the sirocco fan. In this case, the plurality of cartridges may contain drug impregnated bodies impregnated with the same or different drugs.

（式中、Ｘ及びＹは同一又は相異なって水素原子、メチル基、ハロゲン原子又はトリフルオロメチル基を表し、Ｚは水素原子、フッ素原子、メチル基、メトキシメチル基又はプロパルギル基を表す）で表されるフッ素置換ベンジルアルコールエステル化合物を例示することができる。 In the chemical volatilization device of the present invention, the granular or granular chemical impregnated body is required to be stored in a cartridge having a ventilation portion on the side surface. As the chemical, the volatilization amount per hour is 0.01. It is preferable to select a volatile pyrethroid insecticide that can be adjusted to ˜0.5 mg and that can provide sufficient insecticidal efficacy at this dose. Examples of such a drug include general formula (I):

(Wherein X and Y are the same or different and each represents a hydrogen atom, a methyl group, a halogen atom or a trifluoromethyl group, and Z represents a hydrogen atom, a fluorine atom, a methyl group, a methoxymethyl group or a propargyl group). The fluorine-substituted benzyl alcohol ester compound represented can be illustrated.

Specific examples of the compound represented by the general formula (I) include 2,3,5,6-tetrafluorobenzyl-chrysanthemate (hereinafter referred to as Compound A), 2,3,5,6-tetrafluoro. Benzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as Compound B), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2, 2-dichlorovinyl) cyclopropanecarboxylate (hereinafter referred to as Compound C), 4-methyl-2,3,5,6-tetrafluorobenzyl-chrysantemate (hereinafter referred to as Compound D), 4-methyl- 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (hereinafter referred to as Compound E), 4-methyl-2, , 5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-difluorovinyl) cyclopropanecarboxylate (hereinafter referred to as Compound F), 4-methoxymethyl-2,3,5,6 -Tetrafluorobenzyl-chrysanthemate (hereinafter referred to as compound G), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxy Rate (hereinafter referred to as compound H), 2,3,4,5,6-pentafluorobenzyl-2,2-dimethyl-3- (2-chloro-2-trifluoromethylvinyl) cyclopropanecarboxylate (hereinafter referred to as compound) I)) or 4-propargyl-2,3,5,6-tetrafluorobenzyl-3- (1-propenyl) -2,2-dimethyl Black propane carboxylate (hereinafter referred to as Compound J) can be exemplified. As compounds other than the general formula (I), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (Compound K) and 4- Propargyl-2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (Compound L) can also be exemplified. One type of these compounds (drugs) may be used, or two or more types of compounds (drugs) may be used in combination.
In addition, the compound represented by the general formula (I) includes optical isomers and geometric isomers based on the asymmetric carbon or double bond of the acid part, and each of these or any mixture thereof can be used. Of course, the use is also included in the present invention.

  Allethrin and praretrin used as active ingredients for heat transpiration insecticides have poor volatility under the use conditions of the present invention, while empentrin, which has the highest vapor pressure among pyrethroid insecticides, is 1 from the viewpoint of insecticidal efficacy. This is not preferable because a volatilization amount of 2 mg or more per hour is required. Therefore, in the chemical volatilization device of the present invention, the above-mentioned compound having suitable volatility at room temperature is used.

  Examples of the material of the drug impregnated body used in the drug volatilization device of the present invention include cellulose-based carriers such as paper, pulp and viscose, synthetic resin carriers such as ethylene-vinyl acetate resin and olefin polymer, silica Examples include inorganic carriers such as calcium acid, among which natural paper, pulp, and cellulose-based carriers are preferable. These are granular or substantially granular, and are preferably molded so that the average outer diameter is, for example, 3 mm to 10 mm. By adopting such a shape and size of the drug-impregnated body, the pyrethroid insecticide inside the drug-impregnated body gradually moves to the surface and can maintain a stable volatilization amount for a long period of time. . On the other hand, if the average outer diameter is smaller than 3 mm, for example, the volatilization of the drug is rapid and there may be a problem in the sustainability of the insecticidal effect.

Specific shapes of the granular or substantially granular drug-impregnated body include various shapes such as a spherical shape, an elliptical shape, an egg shape, a cylindrical shape, a prism shape, a rod shape, a disc shape, a square plate shape, an indefinite shape, and the like. The size may be various sizes. Further, various drug impregnated materials may be used in combination.
When the drug-impregnated body is stored in the cartridge, the drug-impregnated body having a specific size, shape and material may be stored in the cartridge, or various kinds of drug-impregnated bodies having different sizes, shapes and materials are suitable. They may be mixed at a proper ratio and stored in the cartridge.

Regarding drug impregnated bodies, in addition to using a combination of various kinds of drug impregnated bodies having different sizes, shapes, materials, and numbers, combining various kinds of drug impregnated bodies having different types of impregnated drugs. May be used. Moreover, it can also be used in combination such as mixing various types of drug impregnation bodies having different sizes, shapes, materials, numbers, and types of impregnated drugs.
Therefore, an extremely wide variety of replaceable cartridges containing such a drug impregnated body can be obtained, and these cartridges may be used in appropriate combination depending on the application.
For example, in order to mount on the air outflow side of the sirocco fan, the cartridge preferably has an annular shape, and in order to mount on the air inflow side of the sirocco fan, the cartridge has a disk shape. Those are preferred.

In the present invention, it is preferable to impregnate the drug impregnated body with 100 mg or more of the aforementioned drug as a whole. If the amount of the impregnated drug is less than 100 mg, the sustainability of the insecticidal efficacy may be insufficient. In the impregnation of the chemical, a solvent, a diluent, a surfactant, a dispersant, a sustained release agent, and the like can be used as necessary, and various conventionally known impregnation means can be employed. Furthermore, a stabilizer, a fragrance, a colorant, an antistatic agent, and the like may be appropriately blended in the drug-impregnated body. In addition, as long as the volatilization performance is not hindered in the drug composition, other volatility is high. Insecticides, repellent components (for example, insecticides such as hinokitiol, carvone, safrole, citronellol, and cinnamic aldehyde), acaricides, bactericides, deodorants and the like can be added to form a multipurpose pharmaceutical composition.
In addition, it is more convenient if an indicator function (for example, a discoloration function) indicating an end point of use is added to the drug-impregnated body.

  For example, the cartridge used in the present invention may be provided with a ventilation portion, for example, a configuration in which a large number of opening slits are arranged in parallel, or a net that is fixed to a holder that is arranged in parallel may be configured, but is not limited thereto. . However, in order to prevent the dissipation of the drug impregnated body while ensuring sufficient air permeability so that the condensation of the drug does not affect the volatilization performance, in the case of an open slit, the opening slit width is 1 mm or more and the drug impregnated body. The average outer diameter is preferably 0.7 times or less. The opening ratio of the total opening slit area to the side surface area of the cartridge is preferably set to 0.1 to 0.5, for example. In the case of a net, the distance between the lines is, for example, 1 mm or more and the average outer diameter of the drug-impregnated body The structure set to 0.7 times or less is preferable.

The shape and size of the cartridge can be arbitrarily determined in consideration of the structure of the drug-impregnated body storage portion. As described above, it is preferable that the cartridge is mounted on the air outflow side and / or the air inflow side of the sirocco fan.
Other than those using sirocco fans, for example, a cylindrical cartridge with an outer diameter of 3 to 6 cm and a height of about 2 to 5 cm is easy to use. For example, the central axis of the cartridge is hollow. If this hollow part is shaped so as to fit into the rotating shaft of the main body, it is easy to load the cartridge into the chemical volatilization device main body. In addition, the cartridge may have a substantially conical shape, or may be a type that is loaded into a device having a rotation shaft provided in the lateral direction.

  A protective cover such as a slit shape or a mesh shape is attached around the cartridge so that a finger or the like does not touch the rotating cartridge. You may give the function of the said protective cover to a part of chemical | medical agent volatilization instrument which accommodates the said cartridge. Before use, it is preferable to attach a shielding member (for example, a seal tape) to the ventilation portion of the cartridge in order to prevent the chemical from evaporating from the drug-impregnated body accommodated in the cartridge. The shielding member may be peeled off immediately before use. Use of an adhesive tape as the sealing tape is convenient because it can be easily peeled off. The slit bar portion of the cartridge and the slit bar portion of the protective cover may have a twist angle suitable for a blade shape in order to improve the draft.

A cartridge in which the granular or substantially granular drug-impregnated body has an average outer diameter of 3 mm to 10 mm and the drug-impregnated body is filled in the cartridge with a porosity of 20% to 70% is easy to use, In addition, it is possible to stably volatilize a substantially constant amount of drug over a long period of time, which is particularly preferable for practical use.
The material of the granular or substantially granular drug-impregnated body is not particularly limited. For example, a material composed of at least one selected from paper, pulp, cellulosic carrier and synthetic resin carrier (a single material or a combination of these materials) ) Is preferable as a material constituting the granular or substantially granular drug-impregnated body.

  The present invention will be described more specifically with reference to the following examples and test examples. However, the examples and test examples are only for the purpose of explanation, and the present invention is not limited thereto.

Examples 1-2:
Hereinafter, an example in which a cartridge containing a granular or substantially granular drug impregnated body is mounted on the air outflow side and / or the air inflow side of a sirocco fan will be described.
A) Sirocco Fan FIG. 4 shows a schematic configuration diagram of an example of a sirocco fan. 4A is a top view, FIG. 4B is a side sectional view of FIG. 4A taken along line AA, and FIG. 4C is a bottom view. The sirocco fan 12 is provided with wing portions 13 (slightly curved) protruding inward at regular intervals along the inner periphery of a plastic cylinder, for example, and an opening slit 4 is provided between the wing portions 13. (Not shown) is provided. A motor mounting portion 15 supported by four arm portions 14 is provided at the center of the sirocco fan 12. When the sirocco fan 12 is rotated by the motor, the air flowing from the upper surface side of the sirocco fan 12 flows out through the opening slit 4 due to the wind force generated by the wing part 13.
B) Preparation of cartridge (Example 1)
An example of the cartridge mounted on the air inflow side of the sirocco fan 12 is shown. 200 g of compound A (2,3,5,6-tetrafluorobenzyl-chrysanthemate) is impregnated into 3 g of granular foamed cellulose beads having an average outer diameter of about 6 mm [trade name: Visco Pearl (manufactured by Rengo Co., Ltd.)]. The drug impregnated body 1 obtained in this manner was stored in the drug impregnated body storage portion 3 of the disc-shaped cartridge 2 having an outer diameter of 3 cm and a height of 1 cm. The internal volume of the disc-shaped cartridge 2 is 40 cm 3, and the porosity (ratio of the internal volume remaining as a void without being filled with the drug impregnated body,%) is 50%. The disk-like cartridge 2 is provided with opening slits 4 (not shown) having a width of approximately 2 mm in the height direction on the side surface every 3 mm (pitch interval).
FIG. 2 is a side cross-sectional view of the disk-shaped cartridge 2 according to the first embodiment mounted on the air inflow side of the sirocco fan 12. Since the centrifugal force does not act or hardly acts at the center of the disc-shaped cartridge 2 and its vicinity when the disc-shaped cartridge 2 is rotated, the drug impregnated body 1 is not stored and left as a gap.
FIG. 3 shows the disc-like cartridge 2 of Example 1 in a state where the drug impregnated body 1 is not accommodated. 3A is a top view of the disk-shaped cartridge 2, and FIG. 3B is a side sectional view of the disk-shaped cartridge 2 when FIG. 3A is cut along the line AA. is there. As shown in FIG. 3A, a large number of opening slits 4 such as wedges or rectangles are provided on the upper surface of the disk-shaped cartridge 2.
As shown in FIG. 2, in order to attach the disc-shaped cartridge 2 of Example 1 to the air inflow side of the sirocco fan 12, a holding portion (for holding the disc-shaped cartridge 2 on the air inflow side of the sirocco fan 12 ( For example, a cover part) is required. FIG. 5 shows an example of the lid. 5A is a top view of the lid portion 16, FIG. 5B is a side view of the lid portion 16, and FIG. 5C is a state where the lid portion 16 is mounted on the disc-shaped cartridge 2 of the first embodiment. It is side part sectional drawing shown. Similarly to the upper surface of the disc-shaped cartridge 2, the lid 16 is also provided with a large number of opening slits 4 such as a wedge shape or a rectangle.
C) Chemical volatilization device 1
FIG. 1 shows an example of a chemical volatilization device provided with a sirocco fan 12 to which the disc-shaped cartridge 2 of Example 1 is attached. 1A is a top view of the drug volatilization device, FIG. 1B is a side sectional view of the drug volatilization device, and FIG. 1C is a bottom view of the drug volatilization device. This chemical volatilization device is entirely small and lightweight and can be easily carried. Moreover, since it operates with the dry battery 8, it can also be used outdoors, for example, in a tent.
D) Preparation of cartridge (Example 2)
An example of the cartridge mounted on the air outflow side of the sirocco fan 12 is shown. 400 mg of compound B [2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate] is impregnated into 3 g of pulp having an average outer diameter of about 3 mm. The obtained drug-impregnated body 1 was stored in the drug-impregnated body storage portion 3 of the annular cartridge 2 having an outer diameter of 6.5 cm, an inner diameter of 4 cm, and a height of 2 cm. The internal volume of the annular cartridge 2 is 40 cm @ 3 and the porosity is 20%. The annular cartridge 2 is provided with opening slits 4 (not shown) having a width of approximately 2 mm in the height direction on the side surface every 3 mm.
FIG. 6 shows a state where the annular cartridge 2 of the second embodiment is mounted on the air outflow side of the sirocco fan 12 and the motor 9 is mounted on the sirocco fan 12.
E) Chemical volatilization device 2
FIG. 7 shows an example of a chemical volatilization device including the sirocco fan 12 to which the annular cartridge 2 of Example 2 is attached. FIG. 7A is a top view of the drug volatilization device, FIG. 7B is a side sectional view of the drug volatilization device, and FIG. 7C is a bottom view of the drug volatilization device. Since the annular cartridge 2 is mounted on the air outflow side (outer peripheral part) of the sirocco fan 12, the centrifugal force and wind force accompanying the rotation of the sirocco fan 12 acts effectively, and the volatilization efficiency of the medicine is very good.

Test Example 1: (Examples 3 to 12)
In addition to the drug-impregnated bodies of Examples 1 and 2, according to Example 2, various drug-impregnated bodies (Examples 3 to 12) shown in Table 1 below were prepared. This is housed in the same cartridge as in Example 2 (cartridge in FIG. 6), and the cartridge is mounted on the chemical volatilization device in FIG. 7 and used for 12 hours a day. On the 30th day, the chemical volatilization amount measurement and the insecticidal efficacy test by the following test method (continuous aeration method) were performed. The results are also shown in Table 1 below.
In addition, the insecticidal efficacy is the initial overturning effect when the mosquito-repellent mat containing dl, d-cis, trans-areslin (pinamin forte) is transpired at a heating element heat sink temperature of 160 ° C. As a relative effective ratio.

Test method (continuous ventilation method)
A plastic cylinder with an inner diameter of 20 cm and a height of 43 cm is stacked in two stages, and a cylinder (place where the test mosquito is placed) with an inner diameter and a height of 20 cm both divided by a 16 mesh wire mesh is placed on it. A cylinder with a height of 20 cm and a height of 20 cm is placed. This four-tiered cylinder is placed on a base, and a chemical volatilization device is placed in the center of the base (in the lowermost cylinder) to volatilize the insecticidal component in the chemical-impregnated body. Then, about 20 test mosquitoes are released into the second-stage cylinder from the top, and the number of the test mosquitoes overturned over time is observed. 20 minutes after exposure, all test mosquitoes are transferred to a clean polyethylene container, given 3% sugar water, and examined for mortality 24 hours after storage.

表１に示すとおり、本発明の薬剤揮散用器具によれば、薬剤の揮散量は３０日間の長期間にわたり安定し、この間高い殺虫効力を保持することが認められた。すなわち、実施例１のタイプのカートリッジを備えた図１の薬剤揮散用器具、特に実施例２のタイプのカートリッジを備えた図７の薬剤揮散用器具を使用すると、揮散量の経時変化がほとんどなく、３０日間にわたって、殺虫効果はほぼ一定であり、優れた経時的安定性を有することが判る。

As shown in Table 1, according to the drug volatilization device of the present invention, the volatilization amount of the drug was stable over a long period of 30 days, and it was confirmed that high insecticidal efficacy was maintained during this period. That is, when the chemical volatilization device of FIG. 1 provided with the type 1 cartridge, particularly the chemical volatilization device of FIG. 7 provided with the type 2 cartridge, there is almost no change in volatilization amount with time. It can be seen that over 30 days, the insecticidal effect is almost constant and has excellent temporal stability.

Example 13:
Hereinafter, Example 13 is demonstrated based on FIG. 8, FIG. 200 g of compound A (2,3,5,6-tetrafluorobenzyl-chrysanthemate) is impregnated into 3 g of granular foamed cellulose beads having an average outer diameter of about 6 mm [trade name: Visco Pearl (manufactured by Rengo Co., Ltd.)]. The drug impregnated body 1 (see FIG. 9) obtained in this manner was stored in the drug impregnated body storage portion 3 (see FIG. 9) of the cylindrical cartridge 2 having an outer diameter of 5 cm and a height of 3 cm shown in FIG. 8B. The cartridge 2 is provided with an opening slit 4 having a width of approximately 3 mm in the height direction on the side surface every 3 mm, and the outer cylinder portion having an inner width of 1 cm from the outer peripheral surface is the drug impregnated body storage portion 3. After this cartridge 2 is fitted into the rotation shaft portion 6 of the rotation mechanism portion 5 of the drug volatilization device shown in FIG. 8C (see FIG. 9), and further, the protective cover 7 shown in FIG. The motor 9 was rotated at 500 rpm using the single dry battery 8. When this chemical volatilization device was placed in the center of a 6 tatami room, the chemical volatilization amount per hour (about 4 mg) remained stable with almost no change, and mosquito control over 30 days It was effective. In addition, during use, the rotating sound is not bothered and there is no fear of touching the rotating cartridge, so that the usability is satisfactory.

Example 14:
Hereinafter, Example 14 is demonstrated based on FIG. 10, FIG. Compound H (4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate) 300 mg and stabilizer dibutylhydroxytoluene (BHT) 20 mg Was impregnated into 4 g of substantially granular beads made of pulp and having an average outer diameter of about 3 mm to obtain a drug-impregnated body 1. As shown in FIG. 10, the drug-impregnated body 1 is stored in a cartridge 2 having a cylindrical shape with an outer diameter of 3 cm and a height of 5 cm, and whose side surfaces are composed of ten parallel holders 10 and a net 11 having a distance of 2 mm between lines. The cartridge 2 was loaded into the rotation mechanism 5 of the chemical volatilization device shown in FIG. As shown in FIG. 11A, the medicine volatilization device main body 5 is provided with an opening for volatilizing the medicine in a portion corresponding to the outside of the cartridge 2, and the rotation mechanism of the medicine volatilization device. The opening of the portion 5 also has a function of a protective cover for the cartridge 2. In addition, the chemical volatilization device in FIG. 11 has a rotating shaft provided in the lateral direction as shown in FIG. 11B, FIG. 11A shows a perspective view, and FIG. Shows a side sectional view. This chemical volatilization device matched the interior of the room and showed a sufficient mosquito control effect for 30 days when used for 12 hours a day.

Test Example 2: (Examples 15 to 21)
In addition to the drug-impregnated bodies of Examples 13 and 14, various drug-impregnated bodies (Examples 15 to 21) shown in Table 2 below were prepared according to Example 13. This was loaded into the same chemical volatilization device as in Example 13 (the chemical volatilization device of FIGS. 8 and 9) and used on the first, fifteenth, and thirty days under the conditions of 12 hours per day. The insecticidal efficacy test was performed by measuring the amount of chemical volatilization and the test method described above (continuous aeration method). The results are also shown in Table 2 below.

  As is apparent from the comparison between the results of Table 1 and Table 2, the stability over time is particularly excellent when the cartridge is mounted on the air outflow side and / or the air inflow side, particularly the air outflow side of the sirocco fan. It turns out that it has.

  The present invention can be used for the purpose of controlling a wide range of pests outdoors and indoors.

It is a figure which shows an example of the chemical | medical agent volatilization instrument provided with the sirocco fan equipped with the cartridge of Example 1. FIG. 3 is a side cross-sectional view showing a state where the cartridge of Example 1 is mounted on the air inflow side of the sirocco fan. It is a figure which shows the cartridge of Example 1 of the state which does not accommodate a chemical | medical agent impregnation body. It is a schematic block diagram of an example of the sirocco fan used with the chemical volatilization instrument of the present invention. It is a figure which shows the state which mounted | wore with the cover part used when attaching the cartridge of Example 1 to a sirocco fan, and the said cover part to the cartridge of Example 1. FIG. It is a figure which shows the state which mounts the cartridge of Example 2 in the air outflow side of a sirocco fan, and also mounts a motor on a sirocco fan. It is a figure which shows an example of the chemical | medical agent volatilization instrument provided with the sirocco fan equipped with the cartridge of Example 2. FIG. 16 is a perspective view showing an example of a chemical volatilization device provided with the cartridge of Example 13. It is side part sectional drawing of the instrument for chemical volatilization of FIG. FIG. 22 is a perspective view showing a cartridge according to Example 14. FIG. 16 is a perspective view showing an example of a chemical volatilization device including the cartridge of Example 14.

Explanation of symbols

1: Drug-impregnated body, 2: Cartridge, 3: Drug-impregnated body storage section, 4: Opening slit, 5: Rotating mechanism section of drug volatilization device, 6: Rotating shaft section, 7: Protective cover, 8: Dry cell, 9 : Motor 10: Holder, 11: Net, 12: Sirocco fan, 13: Wing part, 14: Arm part, 15: Motor mounting part, 16: Cover part

Claims (7)

  A granular or substantially granular drug-impregnated body is housed inside, a cartridge having a vent on the side is provided, and a rotation mechanism for the cartridge is provided to volatilize the drug in the drug-impregnated body based on centrifugal force. Device for chemical volatilization.   The drug volatilization device according to claim 1, wherein the drug impregnated body is filled in the cartridge with a porosity of 20% to 70%.   2. The chemical volatilization device according to claim 1, wherein a sirocco fan is attached to the air outflow side and / or the air inflow side of the cartridge.   The drug volatilization device according to claim 3, wherein the cartridge has an annular shape, and the cartridge is mounted on an air outflow side of the sirocco fan.   4. The chemical volatilization device according to claim 3, wherein the cartridge has a disc shape and is mounted on the air inflow side of the sirocco fan. The drug is selected from the following groups: 2,3,5,6-tetrafluorobenzyl-chrysanthemate (Compound A), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1 -Propenyl) cyclopropanecarboxylate (compound B), 2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-dichlorovinyl) cyclopropanecarboxylate (compound C), 4 -Methyl-2,3,5,6-tetrafluorobenzyl-chrysanthemate (compound D), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (1- Propenyl) cyclopropanecarboxylate (Compound E), 4-methyl-2,3,5,6-tetrafluorobenzyl-2,2-dimethyl-3- (2,2-difluorovinyl Cyclopropanecarboxylate (compound F), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl-chrysanthemate (compound G), 4-methoxymethyl-2,3,5,6-tetrafluorobenzyl -2,2-dimethyl-3- (1-propenyl) cyclopropanecarboxylate (compound H), 2,3,4,5,6-pentafluorobenzyl-2,2-dimethyl-3- (2-chloro-2- Trifluoromethylvinyl) cyclopropanecarboxylate (Compound I), 4-propargyl-2,3,5,6-tetrafluorobenzyl-3- (1-propenyl) -2,2-dimethylcyclopropanecarboxylate (Compound J) ), 4-methoxymethyl-2,3,5,6-
Tetrafluorobenzyl-2,2,3,3-tetramethylcyclopropanecarboxylate (compound K) and 4-propargyl-2,3,5,6-tetrafluorobenzyl-2,2,3,3-tetramethylcyclo The device for volatilization of drug according to claim 1, comprising at least one compound selected from propanecarboxylate (compound L).   The drug volatilization device according to claim 1, wherein the granular or substantially granular drug-impregnated body is made of at least one selected from paper, pulp, cellulosic carrier and synthetic resin carrier.

Images