JP2006206499A - Cosmetic material - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a cosmetic material having no stimulation for the skin and the hair, having antioxidation action and capable of keeping the skin and the hair in a healthy state, i.e., the highly safe cosmetic material expressing excellent effects for preventing the rough skin, improving keratin, preventing aging and bringing the skin to be beautiful and improving state and feeling of the hair owing to the antioxidation action. <P>SOLUTION: The cosmetic material is mixed with ionized mineral water. The mineral water preferably contains ≥1 mg/ml at least one ion selected from sodium ion, potassium ion, magnesium ion and calcium ion and has pH 4-8. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention has a non-irritating effect on the skin and hair, has an antioxidative action, and is an excellent makeup for remarkably improving the state of skin wrinkles, skin texture, skin gloss, color, etc. and hair texture. Regarding fees.

  Conventionally, hot spring water or deep sea water is said to be useful for the skin, but its action and usefulness have not been studied much. However, cosmetics formulated with hot spring water and the like are rarely formulated with useful amounts due to microbial problems, distribution and manufacturing costs. In addition, because the salt concentration is low, preservatives must be used due to microbial problems, causing skin irritation and skin texture, color, gloss, etc. related to cosmetics with excellent antioxidant action Or there was a problem that it was insufficient to obtain the effect of remarkably improving the condition of the hair.

  On the other hand, the development of cosmetics that prevent or suppress these effects on oxidation is desired due to the problems of aging and the damage of ultraviolet rays. Skin wrinkles and sagging due to aging, or pigmentation and damage to hair are said to be strongly affected by active oxygen, and as a countermeasure against these, it has antioxidant effects such as ascorbic acid, tocophenol and polyphenol. However, there are many cosmetics containing ingredients having an action of removing active oxygen (see, for example, Patent Documents 1 and 2). These raw materials are expensive and have a problem of poor stability.

  Antioxidants are attracting attention because they have arteriosclerosis prevention and thrombus prevention, liver detoxification action promotion effect, allergy improvement action and the like. These have many oral effects. However, even if it has an antioxidant effect, when it is blended in cosmetics, its mechanism of action is not sufficiently elucidated, and sufficient cosmetics are not provided in terms of cost and stability.

  In addition, although this inventor has discovered that the skin cosmetics which mix | blended the component obtained from a great salt lake have no irritation | stimulation with respect to skin, and are excellent in the rough skin improvement effect and the beautiful skin action (patent document 3). (Refer to this report), and the antioxidant effect was not known at all.

International Publication No. 97/14705 pamphlet JP 2004-175856 A JP 2000-72614 A

  Therefore, as a result of diligent research to solve these problems, the present inventor has found an antioxidant effect in water rich in various ionized minerals, and is highly useful for skin and hair containing these. The present invention was completed after confirming that it was possible to develop inexpensive cosmetics.

  That is, an object of the present invention is to provide a cosmetic that is not irritating to skin and hair, has an antioxidant action, and can keep skin and hair healthy. More specifically, by providing an anti-oxidation effect, it provides a highly stable cosmetic that further improves the condition and feel of the hair while exhibiting further excellent rough skin prevention effects, keratin improvement effects, anti-aging effects, and beautiful skin effects. There is to do.

  In order to achieve the above object, the cosmetic of the present invention contains ionized mineral water. The ionized mineral water preferably contains at least one of sodium ion, potassium ion, magnesium ion and calcium ion at 1 mg / ml or more and has a pH of 4 to 8.

  As described above, according to the present invention, it is possible to provide a cosmetic that is not irritating to skin and hair, has an antioxidant action, and can keep skin and hair healthy. More specifically, by providing an anti-oxidation effect, it provides a highly stable cosmetic that further improves the condition and feel of the hair while exhibiting further excellent rough skin prevention effects, keratin improvement effects, anti-aging effects, and beautiful skin effects. it can. And this cosmetic is stable even if it is stored for a long period of time, and has no side effects or skin irritation that are undesirable for the human body.

  Details of the configuration of the present invention will be described below.

  The ionized mineral water preferably used in the present invention contains at least one of sodium ion, potassium ion, magnesium ion and calcium ion at 1 mg / ml or more. If the content is 1 mg / ml or more, the antioxidant effect is sufficiently obtained, which is preferable. Further, from the viewpoint of skin irritation of the cosmetic of the present invention, it is preferable that the ionized mineral water has a pH of 4 to 8 because it does not become a worrisome range.

  The ionized mineral water is said to have been fresh water after the earth was born, and then the rain that fell from the mountains to the land became rivers that melted the salt on the continental crust and poured it into the sea. It is said that it became salt water. Many are known to have been sun-dried by clogging the water contained in these formations and the water that has flowed in from these rivers due to subsequent crustal movements. Typical examples of what exists in the natural world are the ancient persimmon water (Okinawa Sesoko Island: Japan), Salt Lake (USA), Lake Deborah (Australia), Dead Sea (Israel), and Lake Karne (Egypt) Jellyfish Lake ( Palau).

  For example, persimmon seepage water is pumped from 300m underground in the mainland of Okinawa, Sesoko Island, and is a precious water that has been matured for many years due to the effects of high pressure, blocking light and air. Salt Lake (USA) is concentrated in salt water or natural fire in a secluded, undeveloped area in the northwestern part of Salt Lake City, Utah, USA. The raw water is converted into salt lake IW, Salt Lake OM, Salt Lake by salt concentration. Divided into GM. Furthermore, mineral water (Deborah NM) in Lake Deborah, Western Australia, Australia is mineral water obtained by drying the raw water using the wind of the Indian Ocean. The composition of these mineral waters is shown in Table 1.

The ionized mineral water used in the present invention can be obtained from the mineral water existing in nature shown in Table 1. These contain at least one of sodium ion, potassium ion, magnesium ion and calcium ion in an amount of 1 mg / ml or more, and are suitable for use in the ionized mineral water of the present invention. These mineral waters can be filtered if necessary, and the filtrate can be powdered as it is or freeze-dried and hot-air dried using an excipient such as lactose. It is desirable from the viewpoint.

  The cosmetic composition of the present invention containing the ionized mineral water obtained in this way has ionized minerals such as sodium, magnesium, potassium and calcium acting on the skin and acting synergistically to enhance the function of the skin. To do.

  The extracted mineral water of the present invention can be distributed using a hydrophilic solvent such as hot water, ethanol, glycerin, propylene glycol and the like. In some cases, a heat-treated product, a product sterilized by ultraviolet rays, or a very small amount of a preservative can be added.

  The amount of ionized mineral water in the present invention is preferably 0.005 wt% (abbreviation of weight%) or more and 95 wt% or less based on the total amount of the cosmetic composition in view of the effect and cost. In particular, 0.005 wt% to 50 wt% or less is preferable.

  In addition to ionized mineral water, other cosmetic ingredients can be blended in the cosmetic of the present invention. As the other cosmetic ingredients, any of those that can be usually used can be used, but can be appropriately selected from the following substances depending on the efficacy and effect. For example, excipients and fragrances commonly used in cosmetics, fats and oils, surfactants, moisturizers, whitening agents, pH adjusters, binders, polyhydric alcohols, essential oils and fragrances, Various cosmetic ingredients such as thickeners, preservatives, antioxidants, UV absorbers, pigments, plant pulverized products and herbal medicines, inorganic salts and inorganic acids, cleaning agents, emulsifiers and the like can be mentioned.

  The fats and oils are generally used in cosmetics, for example, soybean oil, almond oil, paraffin, cetanol, avocado oil, olive oil, jojoba oil, coconut oil, palm oil, nuka oil, jojoba oil, egg yolk oil, castor oil. Vegetable oils such as squalane, avocado oil, lanolin, liquid paraffin, white petrolatum; animal fats such as beef tallow, pork fat, horse fat, turtle oil, mink oil, perserine oil, squalane; methylpolysiloxane, behenyl alcohol, tricaprin Examples thereof include synthetic fats and oils such as glyceryl acid, glyceryl trioctanoate, and liquid paraffin.

  Examples of the surfactant include anionic surfactants such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and diethanolamide lauric acid; cationic properties such as stearyltrimethylammonium chloride, cetyltrimethylammonium chloride, and benzalkonium chloride. Surfactant: Nonionic surfactants such as glyceryl monostearate, sorbitan monostearate, polyoxyethylene (20) sorbitan monostearate, polyoxyethylene hydrogenated castor oil, sucrose ester, fatty acid amide, etc. .

  Examples of the humectant include synthetic humectants such as glycerin, propylene glycol, 1,3-butylene glycol, polyoxyglycerin (26E.O), pyrrolidone carboxylate soda, pantethein-S sulfonate; hyaluronic acid, elastin, Examples include natural humectants such as keratin, dermatan sulfate, collagen, placenta extract, royal jelly, microbial fermentation solution such as chitin, chitosan, pectin, and other plant and animal extracts.

  Examples of the whitening agent include placenta extract and extracts derived from other plants and animals in addition to ascorbic acid, arbutin and derivatives thereof.

  Examples of the pH adjuster include organic acids such as citric acid, lactic acid, salicylic acid, tartaric acid, malic acid, benzoic acid, sodium citrate, fumaric acid, sodium monohydrogen phosphate, potassium dihydrogen phosphate, inorganic acids, and the like. Examples thereof include salts thereof.

  The binders are generally used in cosmetics, for example, sodium carboxymethylcellulose, methylcellulose, sodium salt, casein, pectin, starch, sodium alginate, polyvinyl alcohol, polyvinylpyrrolidone, locust bean gum, carrageenan, agar And carbopol.

  Examples of the polyhydric alcohols include glycerin, propylene glycol, sorbitol, polyethylene glycol, and 1,3-butylene glycol.

  The essential oils and perfumes include lavender oil, jasmine oil, rose oil, lemon oil, orange oil, peppermint oil, thyme oil, ginger oil, fennel oil, cedar oil, hiba oil, cypress oil, rose oil, eucalyptus oil, Examples include natural and synthetic fragrances such as camphor, peppermint oil, spearmint oil, geraniol, mandarin oil, spruce, citronellol.

  Examples of the thickener include carboxymethylcellulose, carboxymethylcellulose Na, hydroxymethylcellulose, hydroxyethylcellulose, carboxyvinyl polymer, polyvinyl alcohol, sodium alginate, carrageenan, xanthan gum, bentonite and the like.

  Examples of the preservative include paraoxybenzoic acid esters such as methyl paraben, ethyl paraben, propyl paraben, and butyl paraben, phenoxyethanol, ethanol, and dehydroacetic acid.

  Examples of the antioxidant include alcorbic acid, EDTA4Na, EDTA2Na, butyloxytoluene and the like.

  The ultraviolet absorber is not particularly limited as long as it has a property of selectively absorbing ultraviolet rays. For example, oxybenzone, oxybenzonesulfonic acid, tetrahydroxybenzophenone, sodium dihydroxydimethoxybenzophenonesulfonate, Examples include dihydroxydimethoxybenzophenone, dihydroxybenzophenone, sinoxate, methyl diisopropylcinnamate, octyl methoxycinnamate, glyceryl paraaminobenzoate, octyl paraaminobenzoate, and the like.

  Examples of the pigment include bengara, yellow iron oxide, black iron oxide, titanium oxide, nylon powder, zinc oxide, sericite, mica, and talc. .

  Examples of plant pulverized products and herbal medicines include lemon peel, seaweed, cypress, hiba, fukkas, rice bran, shrimp, ginger, licorice, chimpi, spruce, yuzu, tokyo, carrot, mint, keihi, buckwheat, mugwort, Examples thereof include pulverized products such as dokudami, momonoha, chamomile, aloe, jasmine, rosehip, lavender, guava, ougon, wolfberry, litchi, elderberry, ashitaba, okogi, burdock, black sesame and black rice, and extracts thereof.

Examples of inorganic salts and acids include sodium chloride, sodium bicarbonate, sodium carbonate, boric acid, borax, sodium sulfate, sodium sulfide, potassium sulfide, sodium nitrate, calcium nitrate, ammonium sulfate, sodium thiosulfate, calcium hydrogen phosphate, chloride Examples include potassium, ammonium chloride, sodium phosphate, sodium hyposulfite, calcium thiosulfate, sulfur, sodium sesquicarbonate, magnesium sulfate, anhydrous silicic acid, metasilicic acid, and boric acid.

  Examples of the cleaning agent include sodium lauryl sulfate.

  As the emulsifier, a substance known as a cosmetic raw material can be used. Particularly preferred are sucrose fatty acid esters such as sucrose laurate, sucrose myristic ester, sucrose palmitate, sucrose stearate, sucrose oleate and sucrose erucate; tetraglycerin mono Stearic acid ester, tetraglycerin monooleic acid ester, tetraglycerin tristearic acid ester, hexaglycerin monolauric acid ester, hexaglycerin monomyristic acid ester, hexaglycerin monostearic acid ester, hexaglycerin tristearic acid ester, decaglycerin monolauric acid ester , Decaglycerin monomyristic acid ester, decaglycerin monostearic acid ester, decaglycerin distearic acid ester, decaglycerin Tristearic acid ester, decaglycerin pentastearic acid ester, decaglycerin monoisostearic acid ester, decaglycerin diisostearic acid ester, decaglycerin pentaisostearic acid ester, decaglycerin monooleic acid ester, decaglycerin trioleic acid ester, decaglycerin pentaolein Polyglycerin fatty acid esters such as acid esters; sorbitan branched fatty acid esters such as sorbitan monoisostearate, sorbitan sesquiisostearate, sorbitan triisostearate; soy lecithin, egg yolk lecithin, hydrogenated soy lecithin, hydrogenated egg yolk lecithin, and these Lysolecithin and / or hydrogenated lysolecithin, hydroxyl, which was made into a monoacyl form by enzymatic treatment Lecithins such as the hydroxy lecithin; monoisostearate, glyceryl sesquiisostearate, glyceryl glycerol branched fatty acid esters such diisostearate, glyceryl: and the like can be illustrated, may be used in combination of one or more.

  In addition to the above, the cosmetic of the present invention contains, as necessary, other components such as lactose, milk, condensed milk, titanium, talc and other inorganic pigments, isopropylmethylphenol, chlorohexidine hydrochloride, glucone. Disinfectants such as chlorohexidine acid, vitamins such as vitamin A, vitamin B1, vitamin B2, vitamin B6, vitamin P, CoQ10, CoQ9, CoQ8, fluidizing agents such as silicic anhydride and synthetic aluminum silicate, and pharmaceuticals, pharmaceutical department External products and cosmetic tar pigments can be appropriately blended.

  EXAMPLES Hereinafter, although this invention is explained in full detail based on an Example and a comparative example, this invention is not limited to these. In addition, the antioxidant evaluation measurement method, blood volume measurement method, skin lightness measurement method, stratum corneum turnover speed measurement method (anti-aging effect), rough skin improvement effect measurement method, and sensory test method described in the Examples are as follows. Street. The unit of the blending amount of each component in the examples and comparative examples is wt%.

(1) Antioxidation evaluation method Method: β-carotene fading method (a method utilizing the disappearance of the color of β-carotene by the linoleic acid peroxide generated with the auto-oxidation of linoleic acid) was used.
Experimental procedure: Place the test tube stand in a thermostat at 50 ° C., extract 100 μl of the test substance into the test tube, add 4.9 ml of linoleic acid-β-carotene mixture, and first measure the absorbance at 470 nm of the control. After quickly returning the reaction solution to the test tube, immediately place it in the test tube stand in the thermostatic chamber. Next, the absorbance of the control is measured in the same manner, and the time when the control moves to the bathtub is set to 0 minute, and thereafter the decrease in absorbance at 30 minutes and 60 minutes is measured. And the oxidation rate with time was calculated | required with the following formula | equation.

Oxidation rate (%) = (Absorbance at 0 minutes−Absorbance over time) / (Absorbance at 0 minute) × 100

Table 2 shows the ionized minerals evaluated by the above method and the antioxidant action of ascorbic acid used as a control. The numerical values in the table are expressed as “average value ± standard error”.

  From these results, it was clear that the antioxidant power was stronger than that of the control ascorbic acid as compared with the control, and the action tended to become stronger as the concentration of magnesium increased.

(2) Blood volume measurement method Measurement was performed using a laser Doppler blood flow meter (Omega Flow). A contact-type variable depth probe was used for the measurement, and the measurement was performed on the lower part of the inner eye corner (depth 0.6 mm). Each measurement was performed for about 20 seconds, and the average value of about 10 seconds where the value was stable was taken as the measurement value. The blood volume before sample continuous use and after 10 days continuous use was measured, and the value obtained by subtracting the value before continuous use from the value after continuous use was defined as the blood volume difference.

(3) Skin brightness difference measurement method L * value was measured using a color difference meter (CR-321: manufactured by Minolta). The measurement was performed 5 times for the lower part of the inner eye corner, and the average value of three points excluding the maximum and minimum values was defined as the skin brightness. The skin lightness before and after 10 days of sample use was measured, and the value obtained by subtracting the value after continuous use from the value after continuous use was defined as the skin lightness difference.

(4) Turnover speed measurement method of stratum corneum Make an ointment containing dansyl chloride, a fluorescent dye, in white petrolatum and apply it to the skin of the subject's forearm for 24 hours, and apply dansyl chloride to the stratum corneum. Osmotic bond. Thereafter, a test sample was applied to the same site twice a day (morning and evening), the fluorescence of dansyl chloride was examined every day, and the number of days until the fluorescence disappeared was defined as the turnover speed of the skin keratin. The turnover speed of the normal skin stratum corneum is 14 to 16 days. However, in the case of aging skin, the turnover speed is extended to around 18 days. On the other hand, when the antiaging effect appears, the turnover speed is shortened to around 12 days.

(5) Measurement test method for rough skin improvement effect The effect of continuous application was examined for 20 middle-aged and older subjects having rough skin on the lower leg for 4 weeks. About 1 g of a sample was applied to the subject's left lower leg test site twice a day, and the skin condition before and after the test was determined according to the following criteria. The lower right leg was used as a control with no sample applied. The judgment results of the test site before and after the test and the control site are compared. When the skin dryness is improved by two or more levels (for example, + → −, ++ → ±) is “effective”, and when the level is improved by one level, “Slightly effective” and “invalid” when there was no change. The test result was shown by the number of subjects who became “effective” and “slightly effective”.

(6) Sensory test method The characteristics of the sample after 20 subjects used the sample continuously for 10 days were evaluated. The evaluation was based on questionnaire items on skin brightness, gloss, smoothness, and elasticity. “Skin became brighter”, “Skin gloss increased”, “Skin became smooth”, “Skin It was shown by the number of respondents who responded.

Example 1, Example 2, Comparative Example 1
For each lotion composition of Example 1, Example 2 and Comparative Example 1 having the composition shown in Table 3, after dissolving component b and component c uniformly, both were mixed and dissolved, and component a was further stirred. In addition, a skin lotion was created. The results of various tests performed on the obtained skin lotion are also shown in Table 3.

  As apparent from Table 3, the skin lotion containing the salt lake OM and the persimmon koji permeated water showed good results in various tests. On the other hand, the skin lotion of Comparative Example 1 showed no significant effect in various tests. In addition, the skin lotions of Examples 1 and 2 did not cause any skin irritation in various tests using human skin.

Example 3 (cream)
In accordance with the following formulation, component b and component c are heated and dissolved at 80 ° C., component c is added to component b with stirring, and each component is sufficiently emulsified and dispersed by vigorous stirring (2500 rpm) for 2.5 minutes with a homogenizer. The mixture was gradually cooled with stirring, component a was added at 45 ° C., and stirring was stopped at 35 ° C. while cooling to prepare a cream.

Example 4 (Sunscreen Cream) A sunscreen cream was prepared in the same manner as in Example 3 according to the following formulation.

-Example 5 (lotion)
Each component of the following formulation was mixed and dissolved by a conventional method to prepare a lotion.

-Example 6 (gel)
Components b, c and d of the following formulation were mixed, dispersed and dissolved, components a to c were added to component d, and uniformly dissolved to prepare a gel.

-Example 7 (gel)
Components b, c and d of the following formulation were mixed, dispersed and dissolved, components a to c were added to component d, and uniformly dissolved to form a gel.

-Example 8 (antiperspirant lotion)
Ingredients b and c of the following formulation were mixed, dispersed and dissolved, and ingredients a to c were added and dissolved uniformly to create an antiperspirant lotion.

Example 9 (milky lotion)
The components b and c of the following formulation are dissolved by heating at 80 ° C., the component c is added to the component b with stirring and emulsified, the mixture is cooled while stirring, the component a is added at 45 ° C., and the mixture is further cooled. Stirring was stopped and cooled to prepare an emulsion.

-Example 10 (pack)
Components b and c of the following prescription were mixed, dissolved and dissolved, components a to c were added and uniformly dissolved to prepare a pack.

Example 11 (sheet pack for whole body)
Components b and c of the following prescription are mixed, dispersed and dissolved, and components c are added and dissolved uniformly. Next, 80 g of this is applied per 1 m ² of component d, and 10
A pack was prepared by cutting into cm ² .

Example 12 (liquid bath agent)
Components b and c of the following formulation were mixed, dispersed and dissolved, components a to c were added, and dissolved uniformly to prepare a liquid bath.

Example 13 (powder bath)
The component a and the component b of the following formulation were stirred and mixed, respectively, and dispersed uniformly to obtain a powder bath.

Example 14 (powder pack cosmetic)
Component c of the following formulation was mixed and dispersed, component a to component d were added, and stirred and mixed uniformly to prepare a powder pack cosmetic.

-Example 15 (stick cosmetics)
The component c of the following formulation was dissolved by heating at 75 ° C., the component a and the component b were added, and the mixture was stirred and mixed uniformly, and poured into a mold to prepare a stick cosmetic.

Example 16 (face wash)
Ingredients b and d of the following formulation are dissolved by heating at 80 ° C., component b is added to component d while stirring, emulsified, cooled while stirring, and added at 45 ° C. and further cooled. Stirring was stopped at 35 ° C. to prepare a face wash.

Example 17 (Soap)
Component b of the following formulation is mixed and dispersed, added to component a and component c, kneaded uniformly, and stamped.

Example 18, Example 19, Comparative Example 2, Comparative Example 3
For 20 in-house panelists, shampoos and rinses having the following composition were used for one week each, and the groups using Examples 18 and 19 containing Salt Lake OM were Example Groups, and Comparative Examples 2 and 3 not containing As a comparative example group, a test was started by dividing a group that was used first by 10 people, and an evaluation was performed using a sample from the opposite group one week later. The touch at the time of use, the unity after use, the gloss of the next day, the feeling of use after continuous use, etc. were evaluated on a 5-point scale, and the average score was calculated. The results are shown in Table 21. The score of evaluation is very good, but it is 5 points. Slightly good is 4 points, normal is 3 points, somewhat bad 2 points, bad, but 1 point is higher, the higher the score is. Moreover, although there was no irritation | stimulation at all, it was 5 points, and although there were some, it was set to 3 points, but it was set to 1 point.

-Example 18, comparative example 2 (shampoo)
Ingredients b and d of the following formulation are dissolved by heating at 80 ° C., uniformly mixed and dissolved, cooled to 45 ° C. with stirring, added with components a and c, further stirred, cooled to 40 ° C., and shampoo It was created.

-Example 19, comparative example 3 (rinse)
Ingredients b and d of the following formulation are dissolved by heating at 80 ° C., component b is added to component d while stirring, emulsified, cooled while stirring, and added at 45 ° C. and further cooled. Stirring was stopped at 35 ° C. to prepare a rinse.

  From the above results, the examples were evaluated excellent in all respects as compared with the comparative examples.

Example 20 (Heartnic)
Component b and component c of the following formulation were mixed and dissolved, respectively, component a to component c were added, uniformly dissolved and filtered to create a hair artic.

-Example 21 (hair restoration)
Component b and component c of the following formulation were mixed and dissolved, respectively, component a to component c were added, uniformly dissolved and filtered to prepare a hair nourishing agent.

Example 22 (hair spray)
Component b and component c of the following formulation were mixed, dispersed and dissolved, added component a to component c, uniformly dissolved and filtered to prepare a hair spray.

  The cosmetics of the present invention of Examples 3 to 22 showed clearly good results in various tests and did not cause skin irritation.

  The cosmetics of the present invention are not particularly limited, but for example, basic cosmetics such as creams, emulsions, lotions, essences, face wash, cleansing materials, packs, makeup cosmetics such as lipsticks, foundations, eye colors, It can be used as toiletries such as body soaps, soaps, shampoos, rinses and conditioners, and hair cosmetics such as hair setting agents.

Claims (2)

Cosmetics containing ionized mineral water. The cosmetic according to claim 1, wherein the ionized mineral water contains 1 mg / ml or more of at least one of sodium ion, potassium ion, magnesium ion and calcium ion and has a pH of 4 to 8.