JP2006182711A - Skin care lotion having bactericidal/disinfectant property and moisture retention and method for producing the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a skin care lotion having bactericidal/disinfectant properties and moisture retention, capable of imparting moisture retention by coating on the skins of the face, head, neck, and hand fingers, and, thereby, preventing and recovering/treating generation of skin troubles such as dry skin and dryness due to various bacteria, skin diseases such as pimples and rashes, and others especially atopic dermatitis, and to provide a method for producing the lotion. <P>SOLUTION: The skin care lotion is produced by adding about 3-15 wt.% glycerol and about 0.3-1.5 wt.% hydroxypropyl cellulose to strong electrolytic acidic water of about pH2.5-5 obtained by electrolysis of pure water by using a three chamber type electrolytic bath and mixing therewith. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

The present invention is applied to the skin of the face, head, neck, and fingers to provide moisture retention, skin problems such as dry skin and roughness caused by germs, skin diseases such as acne, pimples, etc. In particular, the present invention relates to skin water having sterilization / disinfection and moisture retention capable of preventing, recovering and healing atopic dermatitis, and a method for producing the same.

The stratum corneum, which is located on the outermost layer of the skin, is in contact with the epidermis cells filled with moisture at the bottom, and the top is in contact with a dry external environment. Few. Dry skin is bulky and unmoistened when touched, and may crack. These skin symptoms are caused by a decrease in the amount of water contained in the stratum corneum on the skin surface.

If the amount of water contained in the stratum corneum on the skin surface decreases, skin troubles such as thickening occur, and it becomes easy to suffer from skin diseases such as acne and pimples due to various bacteria.

Conventionally, various cosmetics and drugs have been used in order to prevent skin troubles and skin diseases as described above, and to recover and heal, but this is disclosed in the following Patent Document 1 relating to the inventors' invention. One of them is “a lotion or cosmetic using reduced water”.

JP 2002-348208 A

The lotion described in Patent Document 1 or reduced water as a raw material for cosmetics has a strong alkaline pH. This strong alkaline reducing water has excellent flexibility and reducing properties, but it is not suitable for skin diseases such as atopic dermatitis, acne, and pimples. There was a problem that there were restrictions on the product.

The problem to be solved by the present invention is to add glycerin and hydroxypropylcellulose to strong electrolytic acidic water and apply it to the skin as skin-beautifying water, due to sterilization / disinfection and penetrability possessed by strong electrolytic acidic water, Deeply penetrates the skin with strong electrolyzed acidic water to sterilize and disinfect bacteria, and the moisture retaining property of glycerin gives the skin a moisturizing effect. Furthermore, the coating function of hydroxypropyl cellulose allows it to be applied to the skin. In addition, it prevents transpiration of the strong electrolytic acid water and glycerin and maintains the sterilizing / disinfecting and moisturizing functions for a long period of time, skin problems such as roughness, skin diseases such as acne and pimples, etc. Has the ability to sterilize, disinfect and moisturize, while preventing the development of dermatitis Skin softening water and is intended to provide a manufacturing method thereof.

In the present invention, glycerin as a humectant and hydroxypropyl cellulose as a coating agent are mixed in strongly electrolyzed acidic water having a pH of about 2.5 to 5 obtained by electrolyzing pure water using a three-chamber electrolytic cell. The above-mentioned problem has been solved by adopting the means to do.

Skin water produced by adding and mixing glycerin and hydroxypropyl cellulose to strongly electrolyzed acidic water having a pH of about 2.5 to 5 obtained by electrolyzing pure water using a three-chamber electrolytic cell, the face and head When applied to the skin such as the neck and fingers, the strong electrolytic acidic water possesses sterilization / disinfection and penetrability, so that the strong electrolytic acidic water penetrates deeply into the skin to disinfect and disinfect bacteria, and glycerin Moisturizing effect is given to the skin, and the coating function possessed by hydroxypropyl cellulose prevents the transpiration of the strongly electrolyzed acidic water and glycerin applied to the skin, thereby sterilizing / disinfecting function and moisturizing. Maintaining the function for a long time, skin problems such as roughness caused by dry skin, skin diseases such as acne and pimples caused by various bacteria, and other particularly Thereby preventing the occurrence of peak dermatitis, it is possible to its recovery and healing.

A first embodiment of the present invention will be described in detail with reference to the drawings. Strongly electrolyzed acidic water having a pH of about 2.5 to 5 used in the present invention uses electrolyzed water produced by electrolyzing pure water. Conventionally, in a two-chamber electrolytic cell that has been widely used, electrolysis hardly occurs even in tap water level water, so that salt is put in raw water to facilitate the passage of electricity for electrolysis. However, since salt remains in the electrolyzed water obtained in the two-chamber electrolytic cell, it cannot be employed in the present invention.

Strongly electrolyzed acidic water used in the present invention is strongly electrolyzed acidic water produced using the three-chamber electrolytic cell A shown in FIG. That is, the electrolytic cell shown in FIG. 1 is provided with an intermediate chamber 5 between the cathode chamber 1 and the anode chamber 2 by disposing the diaphragms 3 and 4 with a space therebetween, and the cathode chamber 1 and the anode chamber. 2 are formed by disposing a cathode electrode 6 and an anode electrode 7 respectively. Then, when pure water is put into the cathode chamber 1 and the anode chamber 2 and salt water is put into the intermediate chamber 5 and electrolysis is performed, alkaline reduced water having a low redox potential (ORP) is generated in the cathode chamber 1. On the other hand, acidic oxidized water having a high ORP is generated in the anode chamber 2.

In the three-chamber electrolytic cell A, when the intermediate chamber 5 is filled with saline and electrolyzed, sodium ions corresponding to the amount of electricity that flowed into the cathode chamber 1 and chlorine ions into the anode chamber 2 are separated from the diaphragm 3. 4 so that only pure water passes through the cathode chamber 1 and the anode chamber 2 as normal raw water, so that ions that have flowed into the pure water and water in which only the oxidizing chemical species are dissolved are generated. Is done. That is, in the three-chamber electrolytic cell A, an electrolyte such as salt is not added to the raw water, the sterilizing / disinfecting acidic oxidized water (pH 2-6) is present in the anode chamber 2, and the cathode chamber 1 is also present in the cathode chamber 1. Alkaline reduced water (pH 8 to 12) having a low detergency redox potential (ORP) is generated.

In the present invention, strong electrolytic acidic water generated in the anode chamber 2 of the three-chamber electrolytic cell A is used as raw water, but the pH of strong electrolytic acidic water used in the present invention is 2.5 to 2.5. It is preferable that the ORP is +1000 mV (vs. Ag / AgCl) or more, and these are easily obtained by putting a high concentration saline in the intermediate chamber 5 in the electrolysis using the three-chamber electrolytic cell A. Can be generated. In general, it is known that electrolyzed water with high ORP having a strongly acidic pH is excellent in sterilization / disinfection and permeability.

Moisturizing function is provided for strongly electrolyzed acidic water having a pH of about 2.5 to 5, particularly preferably about 3 to 4 and an ORP of +1000 mV or more, particularly preferably about +1100 mV, generated using the three-chamber electrolytic cell. About 3 to 15% by weight of glycerin, particularly preferably about 5 to 10% by weight, and hydroxypropyl cellulose having a coating function of about 0.3 to 1.5% by weight, particularly preferably 0.5 to 1% by weight The skin-beautifying water having the sterilizing / disinfecting and moisturizing properties of the present invention is produced by adding and mixing the degree.

The glycerin is naturally produced in large quantities as a component of fats and oils, obtained as a by-product of soap production, and industrially synthesized from propylene. It has the characteristics that it is colorless and has high viscosity and hygroscopicity and excellent moisture retention.

Further, the hydroxypropyl cellulose is obtained by immersing wood pulp or linter pulp in a high-concentration sodium hydroxide solution to obtain alkali cellulose, which is used as a solution or by squeezing the produced alkali cellulose to produce an excessive amount of sodium hydroxide solution. And propylene oxide is allowed to act to obtain crude hydroxypropylcellulose. Then, this is washed with hot water to remove unreacted substances and by-produced propylene glycol and the like, dried and then pulverized.

Hydroxypropyl cellulose is a cellulose derivative having a hydrophilic group and a lipophilic group in its structure and having both water solubility and organic solvent solubility, and is nonionic. Therefore, it is stable to salts, acids and alkalis, and has moderate surface activity. In addition, since it is excellent in coating properties, it is used as a film coating agent and a protective coating agent. However, in the present invention, the components of strong electrolytic acid water and glycerin applied to the skin are not evaporated from the skin surface. It performs the coating function.

Glycerin and hydroxypropylcellulose having the above characteristics are added and mixed in a predetermined amount of strong electrolytic acidic water to produce skin-beautifying water. When the skin-beautifying water is applied to the skin, in addition to the effect of strong electrolytic acidic water, moisturizing Since glycerin having a function is coated with hydroxypropylcellulose having a coating function, and the transpiration of each component of the strongly electrolyzed acidic water and glycerin is prevented for a long time, the sterilizing / disinfecting effect on the skin and the moisturizing effect Can be maintained.

Then, the present inventor has developed a skin-beautifying water produced by adding 5% by weight of glycerin as a moisturizing agent and 0.5% by weight of hydroxypropylcellulose as a coating agent to strongly electrolyzed acidic water of pH 3, and a moisturizing agent. As the skin water produced by adding 10% by weight of glycerin and 1% by weight of hydroxypropylcellulose as a coating agent to each skin, the change with time of the stratum corneum water amount when applied to the skin was measured, and the results are shown in FIG. Shown in In FIG. 2, “strongly electrolyzed acidic water” is indicated as “strongly oxidized water”.

The measurement was performed using “SKICON-200” manufactured by IBS Co., Ltd. In the measurement method, first, the conductance of the part to be verified of the skin is measured in a state where nothing is done (control). Next, a drop of water is placed on the skin to be examined, and after 10 seconds of moisture absorption, wiped with a dry cloth. Immediately after that, the hygroscopicity is determined by how much the conductance increases, and then 30 seconds. Each time, the measurement is performed for 2 minutes or more, the amount of absorbed water is traced to the outside air, and the keratin moisture retention ability is investigated.

In addition, it measured for the comparison also about the strong electrolysis acidic water of pH3 which does not add purified water, pure water, glycerin, and hydroxypropyl cellulose. In the figure, “strongly oxidized water + α” is obtained by adding 5% by weight of glycerin as a humectant and 0.5% by weight of hydroxypropylcellulose as a coating agent, and “strongly oxidized water + α ′” is a humectant. As a coating agent and 10% by weight of hydroxypropylcellulose as a coating agent.

From the measurement results shown in FIG. 2, the strongly electrolyzed acidic water to which glycerin and hydroxypropyl cellulose are not added has a rapid increase in conductance (μS) (physical property value indicating the ease of current flow) immediately after application to the skin. After that, it suddenly descended and it was found that the water retention ability was inferior. In addition, pure water has a conductance immediately after application of only about half the value of strong electrolyzed acidic water, and gradually decreases with time, and purified water has a conductance immediately after application of only about half of the pure water. However, it gradually decreased over time and became almost the same as pure water, and it was found that pure water and purified water had poor water retention capacity compared to the strong electrolytic acid water.

And, “strongly oxidized water + α ′” obtained by adding 10% by weight of glycerin as a humectant and 1% by weight of hydroxypropylcellulose as a coating agent to strong electrolyzed acidic water, the conductance immediately after coating is the glycerin and hydroxypropylcellulose Although it is slightly inferior to strongly electrolyzed acidic water to which no water is added, it rises to a fairly high conductance, and with the passage of time, maintains almost the same conductance until 60 seconds, and then continues to decline gradually. “Strongly oxidized water + α” to which 5% by weight of glycerin as a humectant and 0.5% by weight of hydroxypropylcellulose as a coating agent are added rises to almost the same position as “strongly oxidized water + α ′” immediately after application. , Then continued to rise until 30 seconds later, then slowly declined, After 0 seconds was found to result in drop down slightly from the "strong acid Kamizu + alpha ''.

As a result of the measurement, it was proved that the moisture retention ability of the skin was good by increasing the amount of the moisturizing agent added to the strongly electrolyzed acidic water.

Furthermore, the present inventor applied skin beautifying water produced by changing the mixing ratio of glycerin as a humectant and hydroxypropyl cellulose as a coating agent to strong electrolyzed acidic water having a pH of 3 and applied it to the skin. That is, FIG. 3 shows a state after 10% by weight of glycerin as a moisturizing agent and 1% by weight of hydroxypropylcellulose as a coating agent are added and mixed to produce skin-beautifying water, applied to the back of the hand, and the applied skin-beautifying water is dried. It is a photograph of. In addition, FIG. 4 shows that skin beautifying water is prepared by adding 5 wt% glycerin and 0.5 wt% hydroxypropyl cellulose to strong electrolyzed acidic water of pH 3 and applying it to the back of the hand, and the applied beautifying skin water is dried. It is a photograph of the later state. Note that FIG. 5 is a photograph showing a state after applying strong electrolyzed acidic water instead of the skin water, and the applied strong electrolyzed acidic water is dried, and FIG. 6 is applying pure water instead of the skin water. In the photographs showing the state after drying, all are shown for comparison with the state after the skin water application. Further, FIG. 7 is a photograph before application of skin beautifying water, etc., for comparison with the state after application of skin beautifying water shown in FIGS.

From the comparison of the photographs of FIGS. 3 to 4, FIGS. 5 to 6 and FIG. 7, the skin water obtained by the production method of the present invention and the skin condition after application of pure water or purified water are used. When applied, the lines are clearly visible and the entire skin is glossy. This is because skin water has better moisture retention ability due to the action of glycerin having moisturizing properties than pure water or purified water, and it is considered to be due to the coating function of hydroxypropylcellulose.

Furthermore, the present inventor considers that the skin water obtained by the production method of the present invention may effectively act on atopic dermatitis, and cooperated with "Kuriyamakai Iida Hospital" in Iida City, Nagano Prefecture. The skin water was applied to several patients with atopic dermatitis and tested. Case photographs taken over time from before application to after application are shown in FIGS. The skin water used in this test was a skin water produced by adding 10% by weight of glycerin and 1% by weight of hydroxypropylcellulose to strongly electrolyzed acidic water of pH 3 at ORP + 1100 mV. In addition, in each said figure, the display of "SCW" and "Mizuskin care" points out the skin water obtained by the manufacturing method of this invention.

Judging from the case photographs shown in FIGS. 8 to 22, it was proved that the skin water obtained by the production method of the present invention has a remarkable effect on atopic dermatitis. The reason for the remarkable effect on atopic dermatitis is due to the synergistic effect of the sterilization / disinfection and permeability of strong electrolyzed acidic water, which is the raw material water, the moisture retention of glycerin and the coating property of hydroxypropylcellulose. Conceivable. That is, the sterilizing / disinfecting component of strong electrolyzed acidic water and the moisturizing component of glycerin penetrate deeply into the epidermal cell part of the skin by the penetrating action of the electrolytic water, sterilize / disinfect, and also moisturize by the hydroxypropylcellulose coating function It is estimated that can be held for a long time.

In Example 1, sterilizing / disinfecting and moisturizing by adding glycerin having a moisturizing function and hydroxypropyl cellulose having a coating function to strongly electrolyzed acidic water produced using a three-chamber electrolytic cell. It describes that skin-beautifying water having the property is produced. However, the sterilization / disinfection, permeability and glycerin moisturizing property of the strongly electrolyzed acidic water, which is the raw water of the present invention, prevent acne, pimples and atopic dermatitis from occurring as well as play a role in their recovery / healing. Therefore, even if hydroxypropyl cellulose having a coating function is not added and mixed, the object can be sufficiently achieved.

That is, the moisture-retaining function is generated in strongly electrolyzed acidic water having a pH of about 2.5-5, particularly preferably about 3-4, and an ORP of +1000 mV or more, particularly preferably about +1100 mV, generated using a three-chamber electrolytic cell. The skin-beautifying water having sterilizing / disinfecting and moisturizing properties according to the present invention can be produced by adding and mixing glycerin having an amount of about 3 to 15% by weight, particularly preferably about 5 to 10% by weight.

It is a schematic explanatory drawing of the three-chamber type electrolytic cell used for the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention. It is a graph which shows the time-dependent change of the amount of stratum corneum when the skin water obtained by the manufacturing method of the skin water which has disinfection / disinfection and moisture retention of this invention, and pure water etc. were applied to the skin for comparison. It is the photograph which apply | coated and tested on the skin the skin water obtained by the manufacturing method of the skin water which has the disinfection / disinfection and moisture retention of this invention. It is the photograph which apply | coated and tested on the skin the skin water obtained by the manufacturing method of the skin water which has the disinfection / disinfection and moisture retention of this invention. It is the photograph of the result of having applied strong electrolysis acidic water to the skin, and having tested. It is a photograph of the result of applying pure water to the skin and testing. It is the photograph of the state before apply | coating beautiful skin water etc. to skin. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time. It is the photograph which apply | coated the skin water obtained by the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention of this invention to the patient of atopic dermatitis, and photographed with time.

Explanation of symbols

A Three-chamber electrolytic cell 1 Cathode chamber 2 Anode chamber 3 and 4 Membrane 5 Intermediate chamber 6 Cathode electrode 7 Anode electrode

Claims (5)

Skin cleansing water having sterilization / disinfection and moisturizing properties, characterized by using strongly electrolytic acidic water having a pH of about 2.5 to 5 obtained by electrolyzing pure water using a three-chamber electrolytic cell. It is characterized by adding glycerin as a humectant and hydroxypropylcellulose as a coating agent to strongly electrolytic acidic water having a pH of about 2.5 to 5 obtained by electrolyzing pure water using a three-chamber electrolytic cell. A method for producing skin beautifying water having sterilization / disinfection and moisture retention. In the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention property using the strong electrolysis acidic water of about pH2.5-5 obtained by electrolyzing pure water using the three-chamber type electrolytic cell of Claim 2 Further, skin beautifying water having sterilizing / disinfecting and moisturizing properties, characterized in that about 3 to 15% by weight of glycerin as a moisturizing agent and about 0.3 to 1.5% by weight of hydroxypropyl cellulose as a coating agent are added and mixed. Production method. Sterilization / disinfection and moisturization characterized by adding glycerin as a moisturizer to strong electrolytic acid water having a pH of about 2.5 to 5 obtained by electrolyzing pure water using a three-chamber electrolytic cell Method for producing beautiful skin water. In the manufacturing method of the skin water which has disinfection, disinfection, and moisture retention property using the strong electrolysis acidic water of about pH2.5-5 obtained by electrolyzing pure water using the three-chamber type electrolytic cell of Claim 4 A method for producing skin beautifying water having sterilization / disinfection and moisturizing properties, characterized in that about 3 to 15% by weight of glycerin is added and mixed as a humectant.

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