JP2006175191A - Manual or automatic syringe and its equivalent medical appliance - Google Patents

Manual or automatic syringe and its equivalent medical appliance Download PDF

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JP2006175191A
JP2006175191A JP2004382778A JP2004382778A JP2006175191A JP 2006175191 A JP2006175191 A JP 2006175191A JP 2004382778 A JP2004382778 A JP 2004382778A JP 2004382778 A JP2004382778 A JP 2004382778A JP 2006175191 A JP2006175191 A JP 2006175191A
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syringe
blood
injection
pressure sensor
vein
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Yoshiyuki Ozawa
義行 小澤
Hiroyuki Ozawa
弘行 小澤
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a manual or automatic syringe or its equivalent medical appliance capable of easily and accurately finding a vein, equipped with a diffusion-type semiconductor pressure sensor which can perform an injection, a blood transfusion, a blood collection, an intravenous drip injection, a contrast injection, or the like without giving piercing or other pains to a patient. <P>SOLUTION: When a needle tip of this syringe for transmitting the blood flow of a vein has pierced the vein, the diffusion-type semiconductor pressure sensor 6 for responding to the vascular pressure therein is attached to an appropriate position on the syringe. The pressure strain in a diagram on sensing elements depending on the blood flow transmitted from a pressure port P of the above-mentioned sensor is converted into resistance variations in the strain gauge, and then these variations are taken out in a form of electric signals. These feeble signals are received by a wireless 9 or wired receiver to be amplified, and converted into visible or audible signals, so that the sensor can recognize the penetration of the needle into the vein. Then, it starts performing such medical treatments as the injection, the blood transfusion, the blood collection, and the intravenous drip injection by manipulating the piston of the sylinge. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

発明の詳細な説明Detailed Description of the Invention

本発明は、手動或は自動注射器又はその均等医療器具、詳しくは血流に感応する拡散型半導体圧力センサ−を備え、これに伝達される血液に依る圧力歪みを、その出力端子で電気信号に変換し、この信号を無線又は有線受信器で捕捉し、可視又は可聴信号に変換して自覚し、この信号に従って血液の逆流を派生さす事なく爾後の医療処理を実行する様に構成した手動又は自動注射器等の医療器具に関するものである。    The present invention comprises a manual or automatic injector or its equivalent medical device, more specifically a diffusion type semiconductor pressure sensor sensitive to blood flow, and pressure distortion due to blood transmitted to this is converted into an electrical signal at its output terminal. Manually, configured to perform subsequent medical processing without deriving blood backflow according to this signal, captured by a wireless or wired receiver, converted into a visible or audible signal The present invention relates to a medical instrument such as an automatic syringe.

従来、医薬品注射、採血、輸血等に於ては、一般に上腕部をゴムバンド等で締め付けて静脈を浮き立たせ、これに注射針を刺し込んで注射又は採血しているが、人に依ってはなかなか静脈が浮き出ず、又常時注射を繰り返している患者等では、皮膚又は血管が硬化して注射針が通り難く、経験の浅い医療従事者ではその処置に苦労し、又患者にとっては針の刺し込みを繰り返され、場合に依っては恐怖を感じ、苦痛を伴う治療ともなる場合さえあった。      Conventionally, in pharmaceutical injection, blood collection, blood transfusion, etc., the upper arm is generally tightened with a rubber band to lift the vein, and an injection needle is inserted into this for injection or blood collection, but depending on the person In patients who do not easily see veins and are constantly injecting, the skin or blood vessels harden and the needles are difficult to pass, and inexperienced medical workers have difficulty in treatment, and for patients, needle sticks are difficult. It was repeated and sometimes felt frightened and even a painful treatment.

この様な困難又は苦痛を排除する為に、従来提案されているのは皮下注射器のみであり、例えば糖尿病患者えの注射等においては、以下のごとき特殊な注射器が提案されている。
特願2000−60969
In order to eliminate such difficulties or pains, only a hypodermic syringe has been proposed in the past. For example, in the injection of diabetic patients, the following special syringes have been proposed.
Japanese Patent Application 2000-60969

しかしながら、上記特願2000−60969号の技術は、糖尿病患者の携帯用自動注射器及び注射ユニットに関するもので、注射針(3−11)の先端に装着された酵素体(302)、例えばグルコ−ズオキシタ−ゼは、注射針と一緒に患者の皮膚下に刺し通された時、その皮質の血糖値に応じて電荷を形成し、葡萄糖センサ−(307)の導体(305)(306)を経て微弱電流として取り出され、増幅器(311)で増幅された後、マイコン及びモ−タ−を駆動して注射器を必要速度で駆動する様に構成されている。(図27、28及び29参照)      However, the technology of the above Japanese Patent Application No. 2000-60969 relates to a portable automatic injector and an injection unit for diabetic patients, and an enzyme body (302) attached to the tip of an injection needle (3-11), for example, glucosoxyta. When Z is pierced under the patient's skin together with the injection needle, it forms a charge according to the blood glucose level of the cortex and passes through the conductors (305) (306) of the sucrose sensor (307). After being taken out as an electric current and amplified by an amplifier (311), the microcomputer and the motor are driven to drive the syringe at a necessary speed. (See FIGS. 27, 28 and 29)

従って最も利用の多い薬液の静脈注射、輸血、採血、点滴、造影注射等の医療行為には利用出来ず、上記した新任医療従事者の最も苦労するこの種静脈注射等には役立たない技術である。
本発明は、この種静脈注射等の不利、不便を克服し、医療上の使用効率を挙げる事を課題とするものである。
Therefore, it cannot be used for medical activities such as intravenous injection, blood transfusion, blood collection, drip, contrast injection, etc., which is the most frequently used drug solution. .
An object of the present invention is to overcome the disadvantages and inconveniences of this kind of intravenous injection and increase the medical use efficiency.

課題を解決する為の手段Means to solve the problem

斯の如き課題を解決する為に本発明においては、単なる葡萄糖皮下注射に変わるべき血流に感応する拡散型半導体圧力センサ−を、血流の伝達される当該注射器シリンダ−内外の適当位置に取り付け、血流が伝達された時、その圧力に依るセンシングエレメントのダイアフラムの歪み抵抗の変化に対応するその上の電極の歪み変化を、電気信号として捕らえ、この変化を注射器の外部の有線又は無線受信機で受信し、可視又は可聴信号に変換して、正確に注射針の静脈血流との接触状態を確認し、爾後の注射、採血等の医療器の使用をスム−ズ且つ正確に行なう様に構成した事を特徴とするものである。        In order to solve such a problem, in the present invention, a diffusion type semiconductor pressure sensor sensitive to a blood flow to be changed to a simple sucrose injection is attached to an appropriate position inside and outside the syringe cylinder to which the blood flow is transmitted. When the blood flow is transmitted, the change in strain of the electrode on the sensing element corresponding to the change in the strain resistance of the diaphragm of the sensing element depending on the pressure is captured as an electrical signal, and this change is received by wired or wireless reception outside the syringe. It is received by a machine, converted into a visible or audible signal, and the contact state of the injection needle with the venous blood flow is confirmed accurately, and the use of a medical device such as injection and blood collection after sputum is performed smoothly and accurately. It is characterized by having been configured.

発明の効果The invention's effect

従ってほぼ一定している人体の特定部例えば上腕部の一血管静脈部に、注射針を刺通して注射器上の可視又は可聴信号の作動を確認さえすれば、爾後の医療行為を行なうだけであるから、技術の優劣等は無関係となり、又患者の体形、体質又は病歴に依る差別例えば血管の確認及び注射針刺通難易度、或は反復針刺通の為の上皮硬質化に依る技術上の差別化等は無視する事が出来、血管の太さ及び細さ、浮き出る度合い等の差別に依る患者の治療上の苦痛、治療者の苦難を共に取り除く事が出来る。        Therefore, if the operation of a visible or audible signal on a syringe is confirmed by inserting a needle into a specific blood vessel part of the human body, for example, one vascular vein of the upper arm, only medical treatment is performed after sputum. , Technical superiority and inferiority are irrelevant, and discrimination based on the patient's body shape, constitution or medical history, for example, discrimination of blood vessels and difficulty of needle insertion, or technical discrimination due to epithelial hardening for repeated needle insertion It can be ignored, and both the pain and pain of the patient's treatment due to discrimination such as the thickness and thinness of the blood vessels and the degree of relief can be removed.

更に、初心者等えの教育、実習、講習等の手間が省け、夫々の職務に専念する事が出来ると同時に、ゴムバンド、余分な注射針、消毒液、ガ−ゼ等が節約されるので、医療人件費、経費等が削減される。        In addition, it eliminates the need for beginners' education, practical training, training, etc., and allows them to concentrate on their duties, while at the same time saving rubber bands, extra injection needles, disinfectants, gauze, etc. Medical personnel costs and expenses will be reduced.

又、近時の此の種センサ−の生産技術は著しく向上し、種々な寸法、種々な形状のものが提供されると共に、この種センサ−を利用した手動、自動何れの注射器も比較的安価に提供されるので、医療器具産業界での本発明の経済効果は極めて大きいものがあると確信される。        In addition, the production technology of this kind of sensor in recent years has been remarkably improved, and various sizes and shapes are provided, and both manual and automatic syringes using this kind of sensor are relatively inexpensive. Therefore, it is believed that the economic effect of the present invention in the medical device industry is extremely large.

発明を実施する為の最良の形態BEST MODE FOR CARRYING OUT THE INVENTION

斯くの如く本発明の注射器、採血器等は、血液等の微弱な流れにも感応し得る極く小型の拡散型半導体圧力センサ−を、注射器、採血器等の血液流体が伝達される個所に取り付け、この血流の圧力に依るダイアフラムの歪み変化を、その電極の抵抗値の変化として捕らえ、此の微量変化を外部え電気信号として取り出し、増幅後光可視信号又は可聴信号に変換して使用者が確認出来る様に構成したものであるから、信号発生そのものが針先の血管えの刺通したその時であるから、身体の定位置にある静脈えの針先の刺通は、技術の有無に関わりなく容易に行い得るものであるから、血液の逆流も起こる事なく正確に治療行為を実施する事が出来る。
此の様な医療効果及び利益は、此の種圧力センサ−の注射器等えの利用に依ってのみ得られるものである。
以下に図面を参照して本発明の手動或は自動注射器の好個の数実施例を説明する。
As described above, the syringe, blood collection device, etc. of the present invention is an extremely small diffusion type semiconductor pressure sensor that can be sensitive to a weak flow of blood, etc., at a location where blood fluid such as a syringe, blood collection device, etc. is transmitted. Attached, the distortion change of the diaphragm due to the pressure of the blood flow is captured as a change in the resistance value of the electrode, and this minute change is taken out as an external electric signal and converted into a light visible signal or an audible signal after amplification. Since the signal generation itself is at the time when the blood vessel tip of the needle tip is pierced, the needle tip of the vein tip at a fixed position of the body is the presence or absence of technology Because it can be easily performed regardless of blood flow, it is possible to accurately perform the treatment without blood regurgitation.
Such medical effects and benefits can be obtained only by using a syringe or the like of this kind of pressure sensor.
Several preferred embodiments of the manual or automatic injector of the present invention will be described below with reference to the drawings.

本発明の拡散型半導体圧力センサ−付き手動或は自動注射器又は均等医療器具(1)は、通常の如く、主として注射器シリンダ−(2)と、ピストン(3)と、注射針(4)と、此等注射器主部と一体的又は個別的な信号部(12)とより成る。      The manual or automatic syringe or equivalent medical device (1) with a diffusion type semiconductor pressure sensor of the present invention is mainly composed of a syringe cylinder (2), a piston (3), a syringe needle (4), as usual. These syringe main parts and integral or individual signal part (12) are comprised.

此のシリンダ−(2)内には、血流が伝達される最も近い先端内側に、細孔(8’)の設けられ、適当な材料で作られた活栓(8)が嵌合され、その上面に半導体圧力センサ−(6)が装着されている。      In this cylinder (2), a stopcock (8) made of an appropriate material is fitted with a pore (8 ') on the inner side of the nearest tip where blood flow is transmitted. A semiconductor pressure sensor (6) is mounted on the upper surface.

此の半導体圧力センサ−(6)は、図2及び図3に示す如く、その外側容器(14)の上面に一個の導圧口(圧力ポ−ト)(P)を備え、血流の圧力は、矢印方向からセンシングエレメント(S)に伝達され、そのダイアフラム(15)が変形し、此の変形が表面に設けられたストレンゲ−ジに伝達され、最終的に此のストレンゲ−ジの歪みが、電気信号として導体(7)から取り出される様に構成されている。      As shown in FIGS. 2 and 3, this semiconductor pressure sensor (6) is provided with a single pressure inlet (pressure port) (P) on the upper surface of the outer container (14), and the pressure of blood flow. Is transmitted to the sensing element (S) from the direction of the arrow, and the diaphragm (15) is deformed, and this deformation is transmitted to the strain gauge provided on the surface, and finally the strain of the strain gauge is deformed. The electric signal is extracted from the conductor (7).

斯くて導体(7)(7)からの電気信号は、当該注射器(1)とは別個に設けられた無線受信機(12)の受信部(9)で受信され、増幅器(10)で増幅され、可視信号器(11)から光信号として取り出され、此の信号に従って注射器ピストン(3)を(F)方向に引き上げて採血する。      Thus, the electrical signals from the conductors (7) and (7) are received by the receiving section (9) of the wireless receiver (12) provided separately from the syringe (1) and amplified by the amplifier (10). Then, it is taken out as a light signal from the visible signal device (11), and according to this signal, the syringe piston (3) is pulled up in the (F) direction to collect blood.

此の様にして血液は、静脈(8)に刺し通された注射針(4)及びその挿入口(5)を通って圧力ポ−ト(10)に到達し、前記の如く信号を発信した後吸引され、活栓(8)を通ってシリンダ−(2)内に吸引採血される。      In this way, the blood reaches the pressure port (10) through the injection needle (4) pierced through the vein (8) and its insertion port (5), and transmits a signal as described above. After that, the blood is sucked and drawn through the stopcock (8) into the cylinder (2).

図4には、図3の無線式圧力センサ−電気信号受信方式に代る有線受信方式の採血器(41)が示されている。
此の採血器(41)に於ては、ピストン(43)の外側先端上に、上記と同様な拡散型半導体圧力センサ−(46)が装着され、注射針(44)及びその挿入口(45)を通って矢印方向から血液が流入して電気信号を発生し、コ−ド線(47)及びその端子(48)、受信器(49)、増幅器(50)を経て光信号(51)として発信され、此の信号の確認後、ピストン(43)は、矢印(F)方向に引き上げられ採血される。
FIG. 4 shows a blood collection device (41) of a wired reception system that replaces the wireless pressure sensor-electrical signal reception system of FIG.
In this blood collection device (41), a diffusion type semiconductor pressure sensor (46) similar to the above is mounted on the outer tip of the piston (43), and the injection needle (44) and its insertion port (45). ) Through which blood flows from the direction of the arrow to generate an electrical signal, which passes through the cord wire (47) and its terminal (48), receiver (49), and amplifier (50) as an optical signal (51). After confirming this signal, the piston (43) is pulled up in the direction of arrow (F) and blood is collected.

図5には、超小型の拡散型半導体圧力センサ−(66)を、薬液又は血液注入シリンダ−の外側又は内側先端に装着した微量液注入ポンプ付き携帯注射器(61)が示されている。
此のシリンジポンプ注射器(61)は、通常の如く、その内部にコンピュ−タ−制御の小型電動機を内包し、此の電動機の駆動に依って注射器シリンダ−(62)内でネジ駆動されるピストンの微小運動に従い、正確に薬液若しくは血液を注射する様に構成されているが、此の注射運動の始動は、上記実施例(1)(2)と同様な半導体圧力センサ−(66)が、血流を伝達される適当個所、例えば図6に示す如く、注射器シリンダ−(62)と注射針連結チュ−ブ(65)とのコネクタ−連結部(63)の外側先端又は前記注射器シリンダ−(62)の内側先端(図示せず)に装着されている。
FIG. 5 shows a portable syringe (61) with a microfluid injection pump in which an ultra-small diffusion type semiconductor pressure sensor (66) is mounted on the outer or inner tip of a drug solution or blood injection cylinder.
This syringe pump syringe (61), as usual, contains a computer-controlled small electric motor therein, and a piston that is screw-driven in the syringe cylinder (62) by driving the electric motor. According to the minute movement, the liquid medicine or blood is accurately injected. The injection movement is started by the semiconductor pressure sensor (66) similar to the above embodiments (1) and (2). As shown in FIG. 6, for example, as shown in FIG. 6, a connector-connecting portion (63) between the syringe cylinder (62) and the syringe needle connecting tube (65) or the syringe cylinder ( 62) is attached to the inner tip (not shown).

その使用に際しては、適当な注射液の充満された注射器シリンダ−(62)に連結されている蝶型注射針(68)が、先ず患者の静脈上又はその近辺から刺し込まれ、血管を探り当ててそれを刺し通し、血流がチュ−ブ(67)を通って前記コネクタ−(65)内の圧力センサ−(66)に伝達されると、上記した様に此のセンサ−から出力された電気信号は、無線又は有線受信器(図示せず)を介して受信され、可視信号器(69)の光信号に変換されて警報する。        In its use, a butterfly needle (68) connected to a syringe cylinder (62) filled with an appropriate injection solution is first inserted into or near the patient's vein to locate the blood vessel. When it is pierced and blood flow is transmitted to the pressure sensor (66) in the connector (65) through the tube (67), the electric power output from the sensor is output as described above. The signal is received via a wireless or wired receiver (not shown) and is converted into an optical signal from a visible signal device (69) to alert.

此の信号を受信した操作者は、計器部(64)の注射器電動機(図示せず)の駆動ボタン(71)を押して注射を開始し、前記シリンダ−(62)と聯動するピストンをギヤ−並びにネジで注射速度を調節しながら、極微量の定量薬液又は血液を自動的に注射し、ボタン(72)を押してその医療行為を完了する様に構成されている。        The operator who has received this signal presses the drive button (71) of the syringe motor (not shown) of the meter section (64) to start the injection, and the cylinder (62) and the piston which swings are connected to the gear and the piston. While adjusting the injection speed with a screw, it is configured to automatically inject a minute amount of liquid medicine or blood and press the button (72) to complete the medical action.

斯くの如く、本発明の無線、有線又は手動或は自動拡散型半導体圧力センサ−付き注射器(ロボット注射器)(1)、(41)及び(61)は、患者の体質、体形、病歴及び治療経験等には関係なく、簡単且つ正確に静脈を探り当てる事が出来ると同時に、血液の流れを逆流する事もなく、薬液注射、輸血、採血、点滴、造影注射等の医療器具にも応用出来、その経済的効果は国内だけでも多大にも及ぶと推測され、加えて治療者例えば医療従事者えの技術教育、教習、等の手間が省け、夫々の職務に専念する事が出来、患者自身も注射針の誤刺通等の苦痛、恐怖を避ける事が出来るので、その利用価値は測りえない程多大であると見做す事が出来る。        Thus, the syringes (1), (41) and (61) of the present invention with wireless, wired or manual or automatic diffusion type semiconductor pressure sensor (1), (41) and (61) are the patient's constitution, figure, medical history and treatment experience. It is possible to find veins easily and accurately regardless of, etc., and at the same time, without backflow of blood, it can also be applied to medical instruments such as drug injection, blood transfusion, blood collection, infusion, contrast injection, etc. The economic effect is estimated to be very large in Japan alone, and in addition, it is possible to concentrate on the respective duties by eliminating the time and effort of therapists, such as medical staff, technical training, training, etc. Since it can avoid the pain and fear of needle piercing, it can be considered that its utility value is so great that it cannot be measured.

本発明の拡散型半導体圧力センサ−付き手動注射器の一部切断斜視図である。It is a partial cutaway perspective view of the manual injection device with a diffusion type semiconductor pressure sensor of the present invention. 上記注射器に使用する拡散型半導体圧力センサ−の切断斜視図である。It is a cutaway perspective view of the diffusion type semiconductor pressure sensor used for the syringe. 図1の線A−Aに沿って切断した切断平面図である。It is the cutting | disconnection top view cut | disconnected along line AA of FIG. 本発明の手動注射器の他の態様を示す切断正面図である。It is a cutting | disconnection front view which shows the other aspect of the manual injection device of this invention. 本発明の更に他の態様の自動注射器の一部切断斜視図である。FIG. 6 is a partially cut perspective view of an automatic injector according to still another embodiment of the present invention. 図5の自動注射器の一部切断正面図である。FIG. 6 is a partially cut front view of the automatic injector of FIG. 5.

符号の説明Explanation of symbols

1 拡散型半導体圧力センサ−付き手動注射器
2 シリンダ−
3 ピストン
4 注射針
6 拡散型半導体圧力センサ−
7 電気信号取出しリ−ド線
8 活栓
P 圧力ポ−ト
9 無線受信器
10 増幅器
11 可視信号
1 Manual syringe with diffusion type semiconductor pressure sensor 2 Cylinder
3 Piston 4 Injection needle 6 Diffusion type semiconductor pressure sensor
7 Electrical signal lead wire 8 Stopcock P Pressure port 9 Wireless receiver 10 Amplifier 11 Visible signal

Claims (3)

手動或は自動注射器又は均等医療器具において、針先に掛かる血流に感応する半導体圧力センサ−を、前記注射器等の血流を伝達する個所に装着し、この血流に依って前記センサ−の出力部に誘起される電気信号を、可視又は可廰信号に変換し、この信号の確認後、血液の逆流を派生する事なく、採血、点滴等の医療処置を開始する様に構成した事を特徴とする医療器具。          In a manual or automatic syringe or an equivalent medical device, a semiconductor pressure sensor that is sensitive to blood flow applied to the needle tip is attached to a place where blood flow is transmitted, such as the syringe, and the sensor is controlled by the blood flow. An electrical signal induced in the output unit is converted into a visible or a sensible signal, and after confirming this signal, medical procedures such as blood collection and infusion are started without deriving blood backflow. Features medical equipment. 前記圧力センサ−を、前記注射器又は均等医療器具のシリンダ−内外の最先端部又はピストンの外側先端部に装着した事を特徴とする請求項1記載の医療器具。          2. The medical device according to claim 1, wherein the pressure sensor is attached to a distal end portion inside or outside the cylinder of the syringe or the equivalent medical device or an outer front end portion of a piston. 前記圧力センサ−の出力側に誘起される電気信号を、無線又は有線受信手段で受信して可視又は可聴信号に変換する事を特徴とする請求項1又は2記載の医療器具。          3. The medical device according to claim 1, wherein an electrical signal induced on the output side of the pressure sensor is received by a wireless or wired receiving means and converted into a visible or audible signal.
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US7775215B2 (en) 2005-02-24 2010-08-17 Ethicon Endo-Surgery, Inc. System and method for determining implanted device positioning and obtaining pressure data
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US7927270B2 (en) 2005-02-24 2011-04-19 Ethicon Endo-Surgery, Inc. External mechanical pressure sensor for gastric band pressure measurements
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US7699770B2 (en) 2005-02-24 2010-04-20 Ethicon Endo-Surgery, Inc. Device for non-invasive measurement of fluid pressure in an adjustable restriction device
US7775215B2 (en) 2005-02-24 2010-08-17 Ethicon Endo-Surgery, Inc. System and method for determining implanted device positioning and obtaining pressure data
US7775966B2 (en) 2005-02-24 2010-08-17 Ethicon Endo-Surgery, Inc. Non-invasive pressure measurement in a fluid adjustable restrictive device
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US8870742B2 (en) 2006-04-06 2014-10-28 Ethicon Endo-Surgery, Inc. GUI for an implantable restriction device and a data logger
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JP2008302194A (en) * 2007-06-06 2008-12-18 Mallinckrodt Inc Medical fluid injector having wireless pressure monitoring feature
US10702174B2 (en) 2007-06-27 2020-07-07 Integra Lifesciences Corporation Medical monitor user interface
WO2009088371A1 (en) * 2008-01-08 2009-07-16 Choon Meng Ting Method and apparatus for intra-articular injection or aspiration
CN101909531A (en) * 2008-01-08 2010-12-08 陈崇铭 Method and apparatus for intra-articular injection or aspiration
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US9636070B2 (en) 2013-03-14 2017-05-02 DePuy Synthes Products, Inc. Methods, systems, and devices for monitoring and displaying medical parameters for a patient
CN112741706B (en) * 2019-10-29 2024-05-14 北京大学第三医院(北京大学第三临床医学院) Method and device for preparing diffusion source and method for measuring physiological parameters of extracellular space of solid tissue
CN112741706A (en) * 2019-10-29 2021-05-04 北京大学第三医院(北京大学第三临床医学院) Method and device for preparing diffusion source and method for measuring physiological parameter of extracellular space of solid tissue
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