CN113730729A - Manual and electric integrated insulin injection pen and injection method thereof - Google Patents
Manual and electric integrated insulin injection pen and injection method thereof Download PDFInfo
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- CN113730729A CN113730729A CN202111070240.5A CN202111070240A CN113730729A CN 113730729 A CN113730729 A CN 113730729A CN 202111070240 A CN202111070240 A CN 202111070240A CN 113730729 A CN113730729 A CN 113730729A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/50—General characteristics of the apparatus with microprocessors or computers
- A61M2205/52—General characteristics of the apparatus with microprocessors or computers with memories providing a history of measured variating parameters of apparatus or patient
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E60/00—Enabling technologies; Technologies with a potential or indirect contribution to GHG emissions mitigation
- Y02E60/10—Energy storage using batteries
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Abstract
The utility model provides a manual and electric integrative insulin injection pen, including the cap for brush, the refill, the syringe needle, the refill cover, the main casing, power component, a controller, miniature continuation of journey battery and measurement ring, the cap for brush, the refill, the syringe needle, refill cover and main casing concentric and all along controlling the direction level setting, refill cover fixed cover is in the outside of refill, cap plug-in cover is in the outside of refill cover, syringe needle fixed mounting is at the left end center of refill cover, the right-hand member of syringe needle and the inside intercommunication of refill, the right-hand member of refill passes through the left end of coupling assembling and main casing and is connected, refill inside seal slides and is provided with the injection piston, power component drive injection piston removes left, miniature continuation of journey battery is connected with power component and controller electricity respectively, controller and power component signal connection. The invention has scientific design and reasonable structure, can carry out insulin liquid injection in an electric control mode and can also carry out insulin liquid injection in a manual control mode, is more suitable for carrying about and is convenient to use.
Description
Technical Field
The invention relates to the field of insulin injection devices, in particular to a manual and electric integrated insulin injection pen and an injection method thereof.
Background
Treatment of diabetes is a process of integrated management requiring the simultaneous advancement of diet, exercise, medication, blood glucose monitoring and health education. For diabetic patients, treatment of the disease is a comprehensive management process, and diet, exercise, medicine, blood sugar monitoring and health education of five-horse-ride are required and driven together. The diabetes treatment protocol was developed essentially following the route of "lifestyle intervention → oral hypoglycemic therapy → insulin therapy". If the treatment is not carried out in time, the blood sugar fluctuation can cause damage to body organs and accelerate the occurrence of complications. Diabetes is a lifelong disease, and the current medical level can not eradicate the cure, so that lifelong treatment is needed, and the occurrence of complications is delayed by using hypoglycemic drugs to control blood sugar.
An insulin injection device is used for infusing insulin to unhealthy human body by simulating the secretion method of insulin in normal human body. The blood sugar of a normal human body is regulated by two parts of insulin secretion, namely the insulin secretion in a continuous basic state, and the insulin secretion has the functions of inhibiting the output of hepatic glucose and keeping the balance between the hepatic glucose and the basic blood sugar so as to maintain the fluctuation of the blood sugar within a certain narrow range. Insulin secretion during meal, carbohydrate is absorbed into blood through gastrointestinal tract after meal, insulin secretion is increased, utilization and storage of glucose are promoted, and hepatic glucose output is inhibited so as to deal with increase of postprandial blood sugar. Therefore, patients requiring insulin therapy need to be supplemented not only for postprandial insulin deficiency but also for basal conditions. Thus, a diabetic can infuse an extremely small basal metabolically required amount every 3-5 minute interval period; for post-prandial, larger doses of insulin are required. Therefore, the insulin injection device is not only used for bathing and other special conditions, but also needs to be carried along during exercise and sleep so as to effectively regulate the blood sugar.
The insulin injection pen is used as an insulin injection device, the tedious process of extracting insulin in an insulin medicine bottle by using an injector can be avoided, a large pile of articles such as the injector, the insulin medicine bottle, sterilized absorbent cotton and the like are not needed when the insulin injection pen is out of the home, and only one insulin injection pen is needed. In addition, the injection process is simpler and more concealed, and the embarrassment of injecting insulin in public places can be avoided. The insulin injection device also brings convenience for patients with poor eyesight or even blindness to inject insulin. Further, the insulin dosage is more accurate, the insulin dosage can be adjusted in 1 unit, the injection process is basically painless, the needle head of the injection is thinner than that of a special insulin syringe, and the injection is basically painless after use.
Most insulin injection pens adopt a manual injection mode, namely, insulin is input into the body of an operator in a manual mode, and the operator needs to be careful to prevent too much or too little injection dosage, which is complicated; another way is automatic injection, which is accomplished by means of a related device and an acousto-optic alarm, and cannot be used normally when no electricity is available in the field.
Disclosure of Invention
The invention aims to provide a manual and electric integrated insulin injection pen and an injection method thereof.
In order to achieve the purpose, the invention adopts the following technical scheme:
a manual-electric integrated insulin injection pen comprises a pen cap, a pen core, a needle head, a pen core sleeve, a main shell, a power assembly, a controller, a micro endurance battery and a metering ring, wherein the pen cap, the pen core, the needle head, the pen core sleeve and the main shell are concentric and are horizontally arranged along the left and right directions, the right end of the pen cap, the right end of the pen core sleeve and the left end of the main shell are open, the pen core sleeve is fixedly sleeved outside the pen core, the pen cap is sleeved outside the pen core sleeve in a plugging and pulling manner, the needle head is fixedly arranged at the center of the left end of the pen core sleeve, the right end of the needle head penetrates through the left ends of the pen core sleeve and the pen core and is communicated with the inside of the pen core, the left end of the needle head is positioned on the left side of the pen core sleeve, the left end of the pen core sleeve is connected with a needle cap connecting assembly sleeved outside the needle head in a plugging and pulling manner, the right end of the pen core is connected with the left end of the main shell through the needle cap, an injection piston is arranged inside of the pen core in a sealing and sliding manner, the pen core, the power assembly, the controller and the micro endurance battery are all arranged in the main shell, the metering ring is sleeved outside the connecting assembly in a sliding mode, the power assembly drives the injection piston to move leftwards, the micro endurance battery is electrically connected with the power assembly and the controller respectively, and the controller is in signal connection with the power assembly.
The power component comprises an electric motor, a gear box, a screw rod and a hollow push rod, the electric motor is fixedly arranged at the right side part in the main shell, the gear box is fixedly arranged at the middle part in the main shell, the outer circumference of the gear box is clamped and fixed with the inner wall of the main shell, the screw rod is concentrically and rotatably arranged at the left side part in the main shell, a pipe column is integrally formed at the middle part of the left end surface of the gear box, the right end of the screw rod concentrically extends into the pipe column and is coaxially connected with the left end of a power output shaft at the center of the gear box into a whole, the left end of the screw rod concentrically penetrates through the connecting component and is positioned at the right side of the right end of the pen core, the hollow push rod is concentrically sleeved outside the screw rod, the right end part of the inner circle of the hollow push rod is provided with an internal thread which is matched and connected with the external thread of the screw rod, the left end of the hollow push rod extends into the pen core and is fixedly connected with the right end surface of the injection piston, and the power shaft of the electric motor is horizontally arranged along the left and right directions, the left end of a power shaft of the electric motor is in transmission connection with a power input shaft of the gear box, the miniature endurance battery is electrically connected with the electric motor, the controller is in signal connection with the electric motor, and the middle part of the right side surface of the main shell is provided with a switch key used for controlling the electric motor to work.
The connecting assembly comprises a first connecting sleeve and a second connecting sleeve, the first connecting sleeve is fixedly sleeved outside the second connecting sleeve concentrically, the left end of the first connecting sleeve is in abutting contact with the right end of the pen core, the right end of the pen core sleeve is sleeved with the left end of the first connecting sleeve and is in threaded connection with the left end of the first connecting sleeve, the second connecting sleeve is sleeved outside the hollow push rod concentrically, the right end of the second connecting sleeve extends into the left side part of the main shell concentrically, a limiting ring plate is integrally formed on the excircle of the right end part of the second connecting sleeve, a limiting cylinder which is concentrically arranged and is sleeved on the right side part of the second connecting sleeve is integrally formed on the inner circle edge of the left end of the main shell, the limiting cylinder is rotatably connected with the second connecting sleeve, the right end of the limiting cylinder extends into the main shell and is in abutting contact with the annular surface of the left side of the limiting ring plate, the left end of the limiting cylinder is positioned on the left side of the main shell, and a plurality of clamping grooves which are circumferentially arrayed are formed on the left end edge of the limiting cylinder, an annular boss is integrally formed on the outer circumference of the right end of the push rod, the diameter of an inner cavity of the second connecting sleeve is larger than the outer diameter of the annular boss, and the inner diameter of a left port of the second connecting sleeve is larger than the outer diameter of the push rod and smaller than the outer diameter of the annular boss
The measuring ring is of a cylinder structure with through left and right, the measuring ring is concentrically and slidably sleeved outside the first connecting sleeve, the inner diameter of the measuring ring is larger than the outer diameter of the limiting cylinder, the right end part of the measuring ring is a horn mouth with a small left part and a large right part, a plurality of clamping blocks arranged in a circumferential array are integrally formed on the inner circumference of the right side part of the measuring ring, a limiting sector plate is uniformly formed on the inner circumference of the measuring ring between every two adjacent clamping blocks, a plurality of sliding through holes arranged in a circumferential array and positioned between the first connecting sleeve and the limiting cylinder are formed on the outer circumference of the right side part of the second connecting sleeve, each limiting sector plate is respectively in one-to-one correspondence with each sliding through hole, the diameter of the inner circle of each limiting sector plate is smaller than the outer diameter of the first connecting sleeve, the inner circle of each limiting sector plate is respectively in corresponding sliding arrangement in each sliding through hole, and each clamping block is respectively in one-to-one corresponding clamping fit with each clamping groove, the inside integrated into one piece in the right side limit of each sliding through-hole has the elasticity cardboard, and the left side limit outside of elasticity cardboard is equipped with the triangle bead, and the interior disc of each spacing sector plate is the circular arc arch, and the left side limit of elasticity cardboard is inserted and is measured in the ring and be located the left side of corresponding spacing sector plate, and the triangle bead corresponds the card and establishes the left side at corresponding spacing sector plate.
The left end face of the gear box is fixedly connected with a reverse stopping device through a plurality of plastic columns, the right end of the second connecting sleeve is sleeved on the left end of the pipe column and is connected together in a rotating mode, the right end of the second connecting sleeve is fixedly connected with a ratchet wheel sleeved outside the pipe column in a rotating mode, the reverse stopping device is sleeved outside the ratchet wheel and is connected in a rotating mode, and a ratchet groove meshed with an excircle ratchet of the ratchet wheel in a matching mode is formed in the reverse stopping inner circle.
Be provided with the interface and the display screen that charge that are connected with miniature continuation of the journey battery electricity on the main casing, the controller embeds has bluetooth module, controller and display screen signal connection.
An injection method of a manual and electric integrated insulin injection pen comprises a manual control mode and an electric control mode:
under the condition that the micro endurance battery is electrified, an electric control mode is selected, when the electric shock-proof pen is used, a pen cap and a needle cap are pulled down, a needle head is inserted into a human body, a switch button is pressed, an electric motor starts to work, the micro endurance battery supplies power to the electric motor, a power shaft of the electric motor rotates and drives a power input shaft of a gear box, a power output shaft of the gear box rotates and drives a screw rod to rotate, the screw rod is in threaded transmission connection with a hollow push rod, the hollow push rod is driven by the screw rod to move leftwards, the hollow push rod pushes an injection piston to move leftwards in a pen core, the injection piston injects insulin liquid to be injected into the human body from the pen core, if the electric quantity of the micro endurance battery is insufficient, the micro endurance battery can be charged firstly through a charging interface, then the insulin liquid is injected through the electric control mode, the injection quantity can be checked through observing a display screen, when the target injection amount is reached, the switch key is pressed again, the electric motor is closed, and the injection is stopped;
if the mini-type endurance battery is insufficient in a field area and cannot be charged, a manual control mode is selected, when the mini-type endurance battery is used, the pen cap and the needle cap are pulled out, the metering ring is pushed leftwards to separate the metering ring from the left end of the main shell, each clamping block is separated from each clamping groove, the outer triangular convex edge of the left side edge of each elastic clamping plate is positioned on the right side of the corresponding limiting sector plate, the inner circular edge of each limiting sector plate is clamped on the right end edge of the first connecting sleeve, the main shell can rotate relative to the second connecting sleeve and the pen core, a user pricks the needle into a human body, one hand grips the pen core sleeve and the metering ring, the other hand grips the main shell, the main shell is rotated to drive the gear box inside to rotate, the power output shaft of the gear box is locked at the moment, the power output shaft of the gear box drives the screw rod to rotate, and the screw rod drives the hollow push rod to move leftwards, the hollow push rod pushes the injection piston to move leftwards in the refill, the injection piston injects insulin liquid to be injected into a human body, the reverse rotation stop rotates relative to the ratchet wheel, the ratchet groove on the reverse rotation stop inner circle and the ratchet on the ratchet wheel excircle are matched to collide, so that a sound is produced, 0.5u of insulin liquid is injected by each sound, and due to the effects of the reverse rotation stop and the ratchet wheel, the main shell is fixed relative to the rotation direction of the refill, only the medicine injection direction can be achieved, a user is prevented from rotating the main shell reversely, the injection amount can be known according to the sound reminding, after the target injection amount is achieved, the main shell stops rotating, the metering ring is reset, all the clamping blocks are correspondingly clamped in all the clamping grooves respectively, and the main shell and the refill can be kept fixed.
The controller records and stores insulin liquid injection amount, the controller can upload the insulin liquid injection amount of the same day and the latest week to an insulin injection pen matched APP on a mobile terminal (a smart phone or a tablet personal computer) through a Bluetooth module, online monitoring of the historical insulin liquid injection amount is realized, the mobile terminal can download data monitored by other intelligent wearable devices into the controller, the controller can provide a reference injection amount after analyzing the data, the reference injection amount is uploaded to the insulin injection pen matched APP on the mobile terminal (the smart phone or the tablet personal computer), a user can directly view the reference injection amount through a display screen, and other people can conveniently view the reference injection amount through the insulin injection pen matched APP;
the specific process of obtaining the reference injection dosage is as follows:
(1) the controller 6 uploads the liquid injection amount of insulin on the same day and the latest week to an insulin injection pen matched APP on a mobile terminal (a smart phone or a tablet personal computer) through a Bluetooth module every morning (0: 00-2: 00);
(2) the mobile terminal (a smart phone or a tablet personal computer) regularly reminds a user of timely filling the blood glucose monitoring result after insulin injection into the APP matched with the insulin injection pen every day;
(3) the mobile terminal (a smart phone or a tablet personal computer) collects motion data of the smart motion device (a smart bracelet or a smart watch) through the NFC module;
(4) the APP matched with the insulin injection pen in the mobile terminal (a smart phone or a tablet personal computer) screens the exercise data, personal basic data of { time, insulin injection amount, exercise amount and blood sugar value } are obtained, missing data are deleted, and data of all other complete items are downloaded to the controller 6 through the Bluetooth module;
(5) the controller 6 establishes a regression equation of the blood sugar value and the time, the insulin injection amount and the exercise amount by a least square method of mathematical statistics on a most recently collected { time, insulin injection amount, exercise amount and blood sugar value } data series (recommended value is more than 160 groups), and marks the regression equation as the regression equation
In the above-mentioned formula,x 1 、x 2 、x 3 respectively "time", "insulin liquid injection amount", "amount of exercise", a11、a22、a33、a12、a13、a23The coefficients are respectively determined by a least square method of mathematical statistics according to the acquired { time, insulin injection amount, exercise amount and blood sugar value } data series;
(6) the minimum blood sugar value is taken as an optimization target, the exercise amount is constrained (for example, the exercise step number is less than 10000 steps), and the insulin injection amount under the requirement of the optimization target is obtained in time, whereinf（x 1 ，x 2 ，x 3 ) The minimum optimization algorithm is a rapid cuckoo-arrangement algorithm, and the flow of the rapid cuckoo-arrangement algorithm is as follows:
a) for a 3-dimensional search space
The fast cuckoo algorithm initializes the population:
wherein the content of the first and second substances,
is a scaling factor, NP is the size of the population, and considering the calculated amount, the preferred NP is 20;
b) the iterative calculation is performed 100 times, or the difference of the target optimization value is less than 0.1 insulin injection unit:
wherein the content of the first and second substances,
and
the ith (1, 2, …, NP) current individual, new individual and current population optimal individual of the G generation are respectively represented;
is a step size scale factor; μ and ν follow a normal distribution, β =1.5, and:
c) in the Baided random walk of the fast cuckoo algorithm, each dimension of an individual updates the step length according to a certain probability, as follows:
wherein the content of the first and second substances,
and
indicates the m-th and n-th individuals in the G-th generation population (m ≠ n ≠ i); r is a scaling factor and is the sum of the scaling factors,
representing the probability of foreign egg discovery, typically 0.25, rand obeys 0,1]Uniformly distributed random numbers of (a); d) in the case of a preferred one,
initially 0.5, decreases with increasing evolution generations G, satisfying the following equation:
(7) the insulin optimal injection amount that quick cuckoo algorithm obtained, rethread bluetooth module upload to remove end (smart mobile phone or panel computer), user's accessible display screen directly looks over and refers to the injection quantity, and the reference injection quantity is conveniently looked over to the supporting APP of other personnel's accessible insulin injection pens.
The invention has scientific design and reasonable structure, can carry out insulin liquid injection in an electric control mode and can also carry out insulin liquid injection in a manual control mode, is more suitable for carrying about and is convenient to use.
Drawings
Fig. 1 is a structural sectional view of the present invention.
Fig. 2 is a schematic diagram of the initial state of the injection process under the manual control mode of the invention.
Fig. 3 is a schematic diagram of an intermediate state of the injection process under manual control of the present invention.
Fig. 4 is a schematic view of the final state of the injection process under the manual control mode of the invention.
FIG. 5 is a schematic view of the connection between the reverse rotation prevention inside the main housing and the ratchet wheel of the present invention.
Fig. 6 is a partially enlarged view of a portion a in fig. 1.
Fig. 7 is a partially enlarged view of fig. 1 at B.
Fig. 8 is an isometric view of a second connection sleeve of the invention.
FIG. 9 is an isometric view of the metering ring of the present invention.
FIG. 10 is an isometric view of the overall construction of the invention with the main housing and metering ring removed.
Detailed Description
The embodiments of the present invention are further described below with reference to the drawings.
As shown in figures 1-10, a manual-electric integrated insulin injection pen comprises a pen cap 1, a pen core 2, a needle head 3, a pen core sleeve 4, a main shell 5, a power assembly, a controller 6, a micro endurance battery 7 and a metering ring 8, wherein the pen cap 1, the pen core 2, the needle head 3, the pen core sleeve 4 and the main shell 5 are concentric and are horizontally arranged along the left and right directions, the right end of the pen cap 1, the right end of the pen core 2, the right end of the pen core sleeve 4 and the left end of the main shell 5 are all open, the pen core sleeve 4 is fixedly sleeved outside the pen core 2, the pen cap 1 is sleeved outside the pen core sleeve 4 in a plugging and pulling manner, the needle head 3 is fixedly arranged at the center of the left end of the pen core sleeve 4, the right end of the needle head 3 penetrates through the left ends of the pen core sleeve 4 and the pen core 2 and is communicated with the inside of the pen core 2, the left end of the needle head 3 is positioned at the left side of the pen core sleeve 4, the left end of the pen core sleeve 4 is connected with a needle cap 9 sleeved outside the pen core 3 in a plugging and pulling manner, the right end of the pen core 2 is connected with the left end of the main shell 5 through a connecting assembly, the inside of the refill 2 is provided with an injection piston 10 in a sealing and sliding manner, a power assembly, a controller 6 and a micro endurance battery 7 are all installed in the main shell 5, a metering ring 8 is sleeved outside the connecting assembly in a sliding manner, the power assembly drives the injection piston 10 to move leftwards, the micro endurance battery 7 is respectively electrically connected with the power assembly and the controller 6, and the controller 6 is in signal connection with the power assembly.
The power assembly comprises an electric motor 11, a gear box 12, a screw 13 and a hollow push rod 14, the electric motor 11 is fixedly arranged at the right side part in the main shell 5, the gear box 12 is fixedly arranged at the middle part in the main shell 5, the outer circumference of the gear box 12 is clamped and fixed with the inner wall of the main shell 5, the screw 13 is concentrically and rotatably arranged at the left side part in the main shell 5, a pipe column 15 is integrally formed at the middle part of the left end surface of the gear box 12, the right end of the screw 13 concentrically extends into the pipe column 15 and is coaxially connected with the left end of a power output shaft at the center of the gear box 12 into a whole, the left end of the screw 13 concentrically penetrates through the connecting assembly and is positioned at the right side of the right end of the pen core 2, the hollow push rod 14 is concentrically sleeved outside the screw 13, the right end part of the inner circle of the hollow push rod 14 is provided with an internal thread matched and connected with the external thread of the screw 13, the left end of the hollow push rod 14 extends into the pen core 2 and is fixedly connected with the right end surface of the injection piston 10, the power shaft of the electric motor 11 is horizontally arranged along the left-right direction, the left end of the power shaft of the electric motor 11 is in transmission connection with the power input shaft of the gear box 12, the micro endurance battery 7 is electrically connected with the electric motor 11, the controller 6 is in signal connection with the electric motor 11, and the middle part of the right side surface of the main shell 5 is provided with a switch key 16 for controlling the electric motor 11 to work.
The connecting assembly comprises a first connecting sleeve 17 and a second connecting sleeve 18, the first connecting sleeve 17 is concentrically and fixedly sleeved outside the second connecting sleeve 18, the left end of the first connecting sleeve 17 is in abutting contact with the right end of the pen core 2, the right end of the pen core sleeve 4 is sleeved with the left end of the first connecting sleeve 17 and is in threaded connection, the second connecting sleeve 18 is concentrically sleeved outside the hollow push rod 14, the right end of the second connecting sleeve 18 concentrically extends into the left side part of the main shell 5, a limiting ring plate 19 is integrally formed on the excircle of the right end of the second connecting sleeve 18, a limiting cylinder 20 which is concentrically arranged and is sleeved on the right side part of the second connecting sleeve 18 is integrally formed on the inner circle edge of the left end of the main shell 5, the limiting cylinder 20 is rotatably connected with the second connecting sleeve 18, the right end of the limiting cylinder 20 extends into the main shell 5 and is in abutting contact with the ring surface of the left side of the limiting ring plate 19, the left end of the limiting cylinder 20 is positioned on the left side of the main shell 5, the left end edge of the limiting cylinder 20 is provided with a plurality of clamping grooves 21 arranged in a circumferential array manner, the outer circumference of the right end of the push rod is integrally formed with an annular boss 22, the diameter of the inner cavity of the second connecting sleeve 18 is larger than the outer diameter of the annular boss 22, and the inner diameter of the left port of the second connecting sleeve 18 is larger than the outer diameter of the push rod and smaller than the outer diameter of the annular boss 22
The measuring ring 8 is a cylinder structure with through left and right, the measuring ring 8 is concentrically and slidably sleeved outside the first connecting sleeve 17, the inner diameter of the measuring ring 8 is larger than the outer diameter of the limiting cylinder 20, the right end part of the measuring ring 8 is a horn mouth with a small left and a large right, a plurality of clamping blocks 23 arranged in a circumferential array are integrally formed on the inner circumference of the right side part of the measuring ring 8, limiting sector plates 24 are uniformly formed on the inner circumference of the measuring ring 8 between every two adjacent clamping blocks 23, a plurality of sliding through holes 25 arranged in a circumferential array and positioned between the first connecting sleeve 17 and the limiting cylinder 20 are arranged on the outer circumference of the right side part of the second connecting sleeve 18, each limiting sector plate 24 is respectively corresponding to each sliding through hole 25, the inner circle diameter of each limiting sector plate 24 is smaller than the outer diameter of the first connecting sleeve 17, the inner circle edge of each limiting sector plate 24 is respectively correspondingly and slidably arranged in each sliding through hole 25, each fixture block 23 is in one-to-one corresponding clamping fit with each clamping groove 21, an elastic clamping plate 26 is integrally formed in the middle of the right side edge of each sliding through hole 25, a triangular rib 27 is arranged outside the left side edge of the elastic clamping plate 26, the inner circular edge of each limiting sector plate 24 is a circular arc bulge, the left side edge of the elastic clamping plate 26 is inserted into the metering ring 8 and is located on the left side of the corresponding limiting sector plate 24, and the triangular rib 27 is correspondingly clamped on the left side of the corresponding limiting sector plate 24.
The left end face of the gear box 12 is fixedly connected with a reverse rotation preventing device 28 through a plurality of plastic columns 31, the right end of the second connecting sleeve 18 is sleeved on the left end of the pipe column 15 and is connected together in a rotating mode, the right end of the second connecting sleeve 18 is fixedly connected with a ratchet wheel 29 sleeved on the outer portion of the pipe column 15, the reverse rotation preventing device 28 is sleeved on the outer portion of the ratchet wheel 29 and is connected in a rotating mode, and a ratchet groove 30 meshed with an excircle ratchet of the ratchet wheel 29 in a matching mode is formed in an inner circle of the reverse rotation preventing device 28.
The main shell 5 is provided with a charging interface (not shown) and a display screen 32 which are electrically connected with the micro endurance battery 7, the controller 6 is internally provided with a Bluetooth module, and the controller 6 is in signal connection with the display screen 32.
The metering ring 8, the controller 6, the micro endurance battery 7, the electric motor 11, the gear box 12, the reverse rotation stop 28, the ratchet wheel 29, the charging interface and the Bluetooth module are all conventional technologies in the prior art, specific construction and working principles are not described in detail, and a control part and a data analysis part in the invention are also conventional computer programs and do not relate to new computer programs.
An injection method of a manual and electric integrated insulin injection pen comprises a manual control mode and an electric control mode:
when the micro-endurance battery 7 is electrified, an electric control mode is selected, when the electric-powered pen cap 1 and the needle cap 9 are pulled down, the needle 3 is inserted into a human body, the switch button 16 is pressed, the electric motor 11 starts to work, the micro-endurance battery 7 supplies power to the electric motor 11, a power shaft of the electric motor 11 rotates and drives a power input shaft of the gear box 12, a power output shaft of the gear box 12 rotates and drives the screw 13 to rotate, the screw 13 is in threaded transmission connection with the hollow push rod 14, the screw 13 drives the hollow push rod 14 to move leftwards, the hollow push rod 14 pushes the injection piston 10 to move leftwards in the pen core 2, the injection piston 10 injects insulin liquid to be injected in the pen core 2 into the human body, if the micro-endurance battery 7 is lack of electricity, the micro-powered electric-driven electric-powered electric-, the injection amount can be checked by observing the display screen 32, and when the target injection amount is reached, the switch key 16 is pressed, the electric motor 11 is turned off, and the injection is stopped;
if the mini-type endurance battery 7 is insufficient in a field area and the mini-type endurance battery 7 cannot be charged, a manual control mode is selected, when the mini-type endurance battery 7 is used, the pen cap 1 and the needle cap 9 are pulled out, the metering ring 8 is pushed leftwards, the metering ring 8 is separated from the left end of the main shell 5, each clamping block 23 is separated from each clamping groove 21, the outer triangular convex edge 27 on the left side of each elastic clamping plate 26 is positioned on the right side of the corresponding limiting sector plate 24, the inner circular edge of each limiting sector plate 24 is clamped on the right end edge of the first connecting sleeve 17 of the first connecting sleeve, then the main shell 5 can rotate relative to the second connecting sleeve 18 and the pen core 2, a user inserts the needle 3 into a human body, holds the pen core sleeve 4 and the metering ring 8 with one hand, holds the main shell 5 with the other hand, the main shell 5 is rotated, the main shell 5 drives the gear box 12 inside to rotate, and the power output shaft of the gear box 12 is locked, the power output shaft of the gear box 12 drives the screw 13 to rotate, the screw 13 drives the hollow push rod 14 to move leftwards, the hollow push rod 14 pushes the injection piston 10 to move leftwards in the pen core 2, the injection piston 10 injects the insulin liquid to be injected in the pen core 2 into a human body, wherein the reverse rotation is opposite to the rotation of the ratchet 29, the ratchet groove 30 on the reverse rotation inner circle is matched with the ratchet on the outer circle of the ratchet 29 to collide, so as to generate sound, each sound represents that 0.5u of insulin liquid is injected, and due to the reverse rotation and the action of the ratchet 29, the rotation direction of the main shell 5 relative to the pen core 2 is fixed, only the direction of injection can be realized, a user is prevented from rotating the main shell 5 reversely, the injection volume can be known according to the reminding of the sound, when the target injection volume is reached, the main shell 5 stops rotating, the metering ring 8 is reset, and all the clamping blocks 23 are correspondingly clamped in each clamping groove 21 respectively, the main shell 5 and the pen core 2 can be kept fixed; so all can carry out insulin liquid injection through above-mentioned two kinds of modes, be more suitable for hand-carry, have the universality, convenient to use.
The controller 6 records and stores insulin liquid injection amount, the controller 6 can upload the insulin liquid injection amount of the same day and the latest week to the matched APP of the insulin injection pen on the mobile terminal (a smart phone or a tablet personal computer) through the Bluetooth module, online monitoring of the historical insulin liquid injection amount is realized, the mobile terminal can download data monitored by other intelligent wearable devices into the controller 6, the controller 6 can provide a reference injection amount after analyzing the data, the reference injection amount is uploaded to the matched APP of the insulin injection pen on the mobile terminal (the smart phone or the tablet personal computer), a user can directly view the injection amount through the display screen 32, and other people can conveniently view the reference injection amount through the matched APP of the insulin injection pen;
the specific process of obtaining the reference injection dosage is as follows:
(1) the controller 6 uploads the liquid injection amount of insulin on the same day and the latest week to an insulin injection pen matched APP on a mobile terminal (a smart phone or a tablet personal computer) through a Bluetooth module every morning (0: 00-2: 00);
(2) the mobile terminal (a smart phone or a tablet personal computer) regularly reminds a user of timely filling the blood glucose monitoring result after insulin injection into the APP matched with the insulin injection pen every day;
(3) the mobile terminal (a smart phone or a tablet personal computer) collects motion data of the smart motion device (a smart bracelet or a smart watch) through the NFC module;
(4) the APP matched with the insulin injection pen in the mobile terminal (a smart phone or a tablet personal computer) screens the exercise data, personal basic data of { time, insulin injection amount, exercise amount and blood sugar value } are obtained, missing data are deleted, and data of all other complete items are downloaded to the controller 6 through the Bluetooth module;
(5) the controller 6 establishes a regression equation of the blood sugar value and the time, the insulin injection amount and the exercise amount by a least square method of mathematical statistics on a most recently collected { time, insulin injection amount, exercise amount and blood sugar value } data series (recommended value is more than 160 groups), and marks the regression equation as the regression equation
In the above-mentioned formula,x 1 、x 2 、x 3 respectively "time", "insulin liquid injection amount", "amount of exercise", a11、a22、a33、a12、a13、a23The coefficients are respectively determined by a least square method of mathematical statistics according to the acquired { time, insulin injection amount, exercise amount and blood sugar value } data series;
(6) the minimum blood sugar value is taken as an optimization target, the exercise amount is constrained (for example, the exercise step number is less than 10000 steps), and the insulin injection amount under the requirement of the optimization target is obtained in time, whereinf（x 1 ，x 2 ，x 3 ) The minimum optimization algorithm is a rapid cuckoo-arrangement algorithm, and the flow of the rapid cuckoo-arrangement algorithm is as follows:
a) to pairIn a 3-dimensional search space
The fast cuckoo algorithm initializes the population:
wherein the content of the first and second substances,
is a scaling factor, NP is the size of the population, and considering the calculated amount, the preferred NP is 20;
b) the iterative calculation is performed 100 times, or the difference of the target optimization value is less than 0.1 insulin injection unit:
wherein the content of the first and second substances,
and
i (1, 2, …, NP) th current individual and new individual respectively representing G-th generation
Individuals and current population optimal individuals;
is a step size scale factor; μ and ν follow a normal distribution, β =1.5, and:
c) in the Baided random walk of the fast cuckoo algorithm, each dimension of an individual updates the step length according to a certain probability, as follows:
wherein the content of the first and second substances,
and
indicates the m-th and n-th individuals in the G-th generation population (m ≠ n ≠ i); r is a scaling factor and is the sum of the scaling factors,
representing the probability of foreign egg discovery, typically 0.25, rand obeys 0,1]Uniformly distributed random numbers of (a); d) in the case of a preferred one,
initially 0.5, decreases with increasing evolution generations G, satisfying the following equation:
(7) the insulin optimum injection volume that quick cuckoo algorithm obtained, rethread bluetooth module upload to remove end (smart mobile phone or panel computer), user's accessible display screen 32 directly looks over and refers to the injection quantity, and the reference injection quantity is conveniently looked over to the supporting APP of other personnel's accessible insulin injection pens.
The above embodiments are merely to illustrate rather than to limit the technical solutions of the present invention, and although the present invention has been described in detail with reference to the above embodiments, those of ordinary skill in the art should understand that; modifications and equivalents may be made thereto without departing from the spirit and scope of the invention and it is intended to cover in the claims the invention as defined in the appended claims.
Claims (8)
1. The utility model provides a manual and electric integrative insulin injection pen which characterized in that: the pen comprises a pen cap, a pen core, a needle head, a pen core sleeve, a main shell, a power assembly, a controller, a micro endurance battery and a metering ring, wherein the pen cap, the pen core, the needle head, the pen core sleeve and the main shell are concentric and are horizontally arranged along the left and right directions, the right end of the pen cap, the right end of the pen core sleeve and the left end of the main shell are all open, the pen core sleeve is fixedly sleeved outside the pen core, the pen cap is sleeved outside the pen core sleeve in an inserting and pulling manner, the needle head is fixedly arranged at the center of the left end of the pen core sleeve, the right end of the needle head penetrates through the left ends of the pen core sleeve and the pen core and is communicated with the inside of the pen core, the left end of the needle head is positioned on the left side of the pen core sleeve, the left end of the pen core sleeve is connected with the needle cap sleeved outside the needle head in an inserting and pulling manner, the right end of the pen core is connected with the left end of the main shell through a connecting assembly, an injection piston is arranged inside the pen core in a sealing and sliding manner, the power assembly, the controller and the micro endurance battery are all arranged in the main shell, the metering ring is sleeved outside the connecting assembly in a sliding mode, the power assembly drives the injection piston to move leftwards, the micro endurance battery is electrically connected with the power assembly and the controller respectively, and the controller is in signal connection with the power assembly.
2. The manual-electric integrated insulin injection pen according to claim 1, characterized in that: the power component comprises an electric motor, a gear box, a screw rod and a hollow push rod, the electric motor is fixedly arranged at the right side part in the main shell, the gear box is fixedly arranged at the middle part in the main shell, the outer circumference of the gear box is clamped and fixed with the inner wall of the main shell, the screw rod is concentrically and rotatably arranged at the left side part in the main shell, a pipe column is integrally formed at the middle part of the left end surface of the gear box, the right end of the screw rod concentrically extends into the pipe column and is coaxially connected with the left end of a power output shaft at the center of the gear box into a whole, the left end of the screw rod concentrically penetrates through the connecting component and is positioned at the right side of the right end of the pen core, the hollow push rod is concentrically sleeved outside the screw rod, the right end part of the inner circle of the hollow push rod is provided with an internal thread which is matched and connected with the external thread of the screw rod, the left end of the hollow push rod extends into the pen core and is fixedly connected with the right end surface of the injection piston, and the power shaft of the electric motor is horizontally arranged along the left and right directions, the left end of a power shaft of the electric motor is in transmission connection with a power input shaft of the gear box, the miniature endurance battery is electrically connected with the electric motor, the controller is in signal connection with the electric motor, and the middle part of the right side surface of the main shell is provided with a switch key used for controlling the electric motor to work.
3. The manual-electric integrated insulin injection pen according to claim 2, characterized in that: the connecting assembly comprises a first connecting sleeve and a second connecting sleeve, the first connecting sleeve is fixedly sleeved outside the second connecting sleeve concentrically, the left end of the first connecting sleeve is in abutting contact with the right end of the pen core, the right end of the pen core sleeve is sleeved with the left end of the first connecting sleeve and is in threaded connection with the left end of the first connecting sleeve, the second connecting sleeve is sleeved outside the hollow push rod concentrically, the right end of the second connecting sleeve extends into the left side part of the main shell concentrically, a limiting ring plate is integrally formed on the excircle of the right end part of the second connecting sleeve, a limiting cylinder which is concentrically arranged and is sleeved on the right side part of the second connecting sleeve is integrally formed on the inner circle edge of the left end of the main shell, the limiting cylinder is rotatably connected with the second connecting sleeve, the right end of the limiting cylinder extends into the main shell and is in abutting contact with the annular surface of the left side of the limiting ring plate, the left end of the limiting cylinder is positioned on the left side of the main shell, and a plurality of clamping grooves which are circumferentially arrayed are formed on the left end edge of the limiting cylinder, an annular boss is integrally formed on the outer circumference of the right end of the push rod, the diameter of an inner cavity of the second connecting sleeve is larger than the outer diameter of the annular boss, and the inner diameter of a left port of the second connecting sleeve is larger than the outer diameter of the push rod and smaller than the outer diameter of the annular boss.
4. The manual-electric integrated insulin injection pen according to claim 3, characterized in that: the measuring ring is of a cylinder structure with through left and right, the measuring ring is concentrically and slidably sleeved outside the first connecting sleeve, the inner diameter of the measuring ring is larger than the outer diameter of the limiting cylinder, the right end part of the measuring ring is a horn mouth with a small left part and a large right part, a plurality of clamping blocks arranged in a circumferential array are integrally formed on the inner circumference of the right side part of the measuring ring, a limiting sector plate is uniformly formed on the inner circumference of the measuring ring between every two adjacent clamping blocks, a plurality of sliding through holes arranged in a circumferential array and positioned between the first connecting sleeve and the limiting cylinder are formed on the outer circumference of the right side part of the second connecting sleeve, each limiting sector plate is respectively in one-to-one correspondence with each sliding through hole, the diameter of the inner circle of each limiting sector plate is smaller than the outer diameter of the first connecting sleeve, the inner circle of each limiting sector plate is respectively in corresponding sliding arrangement in each sliding through hole, and each clamping block is respectively in one-to-one corresponding clamping fit with each clamping groove, the inside integrated into one piece in the right side limit of each sliding through-hole has the elasticity cardboard, and the left side limit outside of elasticity cardboard is equipped with the triangle bead, and the interior disc of each spacing sector plate is the circular arc arch, and the left side limit of elasticity cardboard is inserted and is measured in the ring and be located the left side of corresponding spacing sector plate, and the triangle bead corresponds the card and establishes the left side at corresponding spacing sector plate.
5. The manual-electric integrated insulin injection pen according to claim 4, characterized in that: the left end face of the gear box is fixedly connected with a reverse stopping device through a plurality of plastic columns, the right end of the second connecting sleeve is sleeved on the left end of the pipe column and is connected together in a rotating mode, the right end of the second connecting sleeve is fixedly connected with a ratchet wheel sleeved outside the pipe column in a rotating mode, the reverse stopping device is sleeved outside the ratchet wheel and is connected in a rotating mode, and a ratchet groove meshed with an excircle ratchet of the ratchet wheel in a matching mode is formed in the reverse stopping inner circle.
6. The manual-electric integrated insulin injection pen according to claim 5, characterized in that: be provided with the interface and the display screen that charge that are connected with miniature continuation of the journey battery electricity on the main casing, the controller embeds has bluetooth module, controller and display screen signal connection.
7. The injection method of the manual-electric integrated insulin injection pen according to claim 6, characterized in that: the method comprises a manual control mode and an electric control mode:
under the condition that the micro endurance battery is electrified, an electric control mode is selected, when the electric shock-proof pen is used, a pen cap and a needle cap are pulled down, a needle head is inserted into a human body, a switch button is pressed, an electric motor starts to work, the micro endurance battery supplies power to the electric motor, a power shaft of the electric motor rotates and drives a power input shaft of a gear box, a power output shaft of the gear box rotates and drives a screw rod to rotate, the screw rod is in threaded transmission connection with a hollow push rod, the hollow push rod is driven by the screw rod to move leftwards, the hollow push rod pushes an injection piston to move leftwards in a pen core, the injection piston injects insulin liquid to be injected into the human body from the pen core, if the electric quantity of the micro endurance battery is insufficient, the micro endurance battery can be charged firstly through a charging interface, then the insulin liquid is injected through the electric control mode, the injection quantity can be checked through observing a display screen, when the target injection amount is reached, the switch key is pressed again, the electric motor is closed, and the injection is stopped;
if the mini-type endurance battery is insufficient in a field area and cannot be charged, a manual control mode is selected, when the mini-type endurance battery is used, the pen cap and the needle cap are pulled out, the metering ring is pushed leftwards to separate the metering ring from the left end of the main shell, each clamping block is separated from each clamping groove, the outer triangular convex edge of the left side edge of each elastic clamping plate is positioned on the right side of the corresponding limiting sector plate, the inner circular edge of each limiting sector plate is clamped on the right end edge of the first connecting sleeve, the main shell can rotate relative to the second connecting sleeve and the pen core, a user pricks the needle into a human body, one hand grips the pen core sleeve and the metering ring, the other hand grips the main shell, the main shell is rotated to drive the gear box inside to rotate, the power output shaft of the gear box is locked at the moment, the power output shaft of the gear box drives the screw rod to rotate, and the screw rod drives the hollow push rod to move leftwards, the hollow push rod pushes the injection piston to move leftwards in the refill, the injection piston injects insulin liquid to be injected into a human body, the reverse rotation stop rotates relative to the ratchet wheel, the ratchet groove on the reverse rotation stop inner circle and the ratchet on the ratchet wheel excircle are matched to collide, so that a sound is produced, 0.5u of insulin liquid is injected by each sound, and due to the effects of the reverse rotation stop and the ratchet wheel, the main shell is fixed relative to the rotation direction of the refill, only the medicine injection direction can be achieved, a user is prevented from rotating the main shell reversely, the injection amount can be known according to the sound reminding, after the target injection amount is achieved, the main shell stops rotating, the metering ring is reset, all the clamping blocks are correspondingly clamped in all the clamping grooves respectively, and the main shell and the refill can be kept fixed.
8. The injection method of the manual and electric integrated insulin injection pen according to claim 7, characterized in that: the controller records and stores insulin liquid injection amount, the controller can upload the insulin liquid injection amount of the same day and the latest week to an insulin injection pen matched APP on a mobile terminal (a smart phone or a tablet personal computer) through a Bluetooth module, online monitoring of the historical insulin liquid injection amount is realized, the mobile terminal can download data monitored by other intelligent wearable devices into the controller, the controller can provide a reference injection amount after analyzing the data, the reference injection amount is uploaded to the insulin injection pen matched APP on the mobile terminal (the smart phone or the tablet personal computer), a user can directly view the reference injection amount through a display screen, and other people can conveniently view the reference injection amount through the insulin injection pen matched APP;
the specific process of obtaining the reference injection dosage is as follows:
(1) the controller 6 uploads the liquid injection amount of insulin on the same day and the latest week to an insulin injection pen matched APP on a mobile terminal (a smart phone or a tablet personal computer) through a Bluetooth module every morning (0: 00-2: 00);
(2) the mobile terminal (a smart phone or a tablet personal computer) regularly reminds a user of timely filling the blood glucose monitoring result after insulin injection into the APP matched with the insulin injection pen every day;
(3) the mobile terminal (a smart phone or a tablet personal computer) collects motion data of the smart motion device (a smart bracelet or a smart watch) through the NFC module;
(4) the APP matched with the insulin injection pen in the mobile terminal (a smart phone or a tablet personal computer) screens the exercise data, personal basic data of { time, insulin injection amount, exercise amount and blood sugar value } are obtained, missing data are deleted, and data of all other complete items are downloaded to the controller 6 through the Bluetooth module;
(5) the controller 6 establishes a regression equation of the blood sugar value and the time, the insulin injection amount and the exercise amount by a least square method of mathematical statistics on a most recently collected { time, insulin injection amount, exercise amount and blood sugar value } data series (recommended value is more than 160 groups), and marks the regression equation as the regression equation
In the above-mentioned formula,x 1 、x 2 、x 3 respectively "time", "insulin liquid injection amount", "amount of exercise", a11、a22、a33、a12、a13、a23The coefficients are respectively determined by a least square method of mathematical statistics according to the acquired { time, insulin injection amount, exercise amount and blood sugar value } data series;
(6) the minimum blood sugar value is taken as an optimization target, the exercise amount is constrained (for example, the exercise step number is less than 10000 steps), and the insulin injection amount under the requirement of the optimization target is obtained in time, whereinf（x 1 ，x 2 ，x 3 ) The minimum optimization algorithm is a rapid cuckoo-arrangement algorithm, and the flow of the rapid cuckoo-arrangement algorithm is as follows:
a) for a 3-dimensional search space
The fast cuckoo algorithm initializes the population:
wherein the content of the first and second substances,
is a scaling factor, NP is the size of the population, and considering the calculated amount, the preferred NP is 20;
b) the iterative calculation is performed 100 times, or the difference of the target optimization value is less than 0.1 insulin injection unit:
wherein the content of the first and second substances,
and
the ith (1, 2, …, NP) current individual, new individual and current population optimal individual of the G generation are respectively represented;
is a step size scale factor; μ and ν follow a normal distribution, β =1.5, and:
c) in the Baided random walk of the fast cuckoo algorithm, each dimension of an individual updates the step length according to a certain probability, as follows:
wherein the content of the first and second substances,
and
indicates the m-th and n-th individuals in the G-th generation population (m ≠ n ≠ i); r is a scaling factor and is the sum of the scaling factors,
representing the probability of foreign egg discovery, typically 0.25, rand obeys 0,1]Uniformly distributed random numbers of (a); d) in the case of a preferred one,
initially 0.5, decreases with increasing evolution generations G, satisfying the following equation:
(7) the insulin optimal injection amount that quick cuckoo algorithm obtained, rethread bluetooth module upload to remove end (smart mobile phone or panel computer), user's accessible display screen directly looks over and refers to the injection quantity, and the reference injection quantity is conveniently looked over to the supporting APP of other personnel's accessible insulin injection pens.
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