JP2006169152A - Antimicrobial composition, and filter using the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a bamboo- or bamboo grass-derived antimicrobial agent reduced in discoloration and/or scent while retaining its antimicrobial ability. <P>SOLUTION: The antimicrobial composition comprises bamboo or bamboo grass or extract component(s) thereof, a clathrate compound and iodine. Specifically, the clathrate compound is a cyclodextrin. This antimicrobial composition is usable in filters, one form thereof being a mask. Further, this composition is variously usable in applications where antimicrobial, antiviral and antifungal properties are required to some extent. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to an antibacterial composition and a filter formed by applying the antibacterial composition.

  Bamboo or bamboo shoots, or bamboo or bamboo extract components are known to have antibacterial properties from the beginning. The antibacterial property of bamboo or moth, unlike antibiotics, can block the activity of a wide range of small organisms such as bacteria, fungi, viruses, bacteria, moths, etc. It has been reviewed because it is difficult to become antibiotic resistant. In the present invention, antibacterial is a generic term for antibacterial, antifungal, antiviral, antibacterial, and antifungal.

In particular, bamboo or bamboo shoots extracted with water or an aqueous solvent such as ethyl alcohol are hydrolyzed to increase acidic components such as formic acid, acetic acid, propionic acid, coumaric acid, and caffeic acid. Shows high antibacterial properties. On the other hand, at the same time as the hydrolysis progresses, it comes with a blackish brown coloration and a scent like a burning odor. Is not something
WO99 / 62444 pamphlet

  An object of the present invention is to provide an antibacterial agent derived from bamboo or bamboo grass with reduced coloring and aroma while maintaining antibacterial properties.

  The present invention relates to an antibacterial composition comprising bamboo or straw or an extract component thereof, an inclusion compound, and iodine.

  Moreover, this invention relates to the said antimicrobial composition whose inclusion compound is a cyclodextrin.

  The present invention also relates to the above antibacterial composition, wherein the bamboo or cocoon extraction component is obtained by heat-extracting bamboo or cocoon with a solvent.

  The present invention further relates to the antibacterial composition containing a resin.

  Moreover, this invention relates to the filter formed by apply | coating the said antibacterial composition.

  Moreover, this invention relates to the said filter which is a mask.

  According to the present invention, it is possible to provide an antibacterial agent derived from bamboo or bamboo grass with reduced coloring and fragrance while maintaining antibacterial properties.

  The bamboo or cocoon of the present invention refers to a plant belonging to the family Gramineae. Among them, there are 10 genera such as Mushroom, Narihirada, Tochiku, Okamezasa, Sasa, Azumaza, Yadatake, Medaka, Kanchiku, Horaichiku, and others. Kinmeichiku, black bamboo, Phyllostachys Aurea, pseudosasa japonica, semiarundinaria fastuosa, Suzukonarihira, sinobambusa tootsik, Shihouchiku, Okamesasa, Oroshimachiku, Pleioblastus chino, Kamurozasa, Tan'nasazasa, Fuirishiiya, Kogumasasa, Honkogumasasa, Akebonosasa, Chigozasa, Yakushimazasa, Gotenbazasa, Katsuragizasa, Suzudake, Miyama kumazasa, Nemagaridake, Sasa , Hosobazasa, Kumaizasa, Kumazasa, Chugokusa and the like. These may be one kind or two or more kinds. Moreover, plants other than bamboo or bamboo shoots may be included.

  The form of bamboo or cocoon used in the present invention may include stems, roots, etc., as well as leaves of bamboo or cocoon, and may be those cut and pulverized. Moreover, what extracted these using water or an organic solvent may be used.

As an organic solvent,
Hydrocarbons such as hexane, octane, cyclohexane,
Alcohols such as methanol and ethanol,
Ketones such as acetone and methyl ethyl ketone,
Esters such as ethyl acetate, butyl acetate, ethyl propionate,
Aromatics such as benzene, toluene, xylene,
Halogenated solvents such as dichloroethane and trichloroethane,
Ethers such as diethyl ether and tetrahydrofuran;
Carbon dioxide in a critical state can be appropriately selected.

Extraction is obtained by immersing bamboo or straw in water or an organic solvent, followed by filtration or pressing. You may heat and pressurize in immersion, filtration, and pressing.
The extraction operation may be performed twice or more. The conditions for performing two or more times may be the same or different. Moreover, even if it is continuous, the other process may be pinched | interposed.

  The extracted product may be the extract itself, or may have been subjected to a selection process such as filtration, column purification, solvent washing and the like. Further, it may be in the form of a powder obtained by adding a shaping agent such as spray drying, freeze drying or dextrin.

The antibacterial composition of the present invention further contains an inclusion compound and iodine. Examples of the inclusion compound include cyclodextrins, dextrans, crown ether, calixarene, amylose, cyclofructan, cellulose, thiourea and the like. These clathrate compounds can be used alone or in combination as required.
Cyclodextrins are also called cyclic oligosaccharides, and generally a large number of glucoses linked in a cyclic manner by α-1,4-glucoside bonds. Those having 6 glucose units are referred to as α-cyclodextrin, 7 as β-cyclodextrin, and 8 as γ-cyclodextrin. A unit having 9 to 12 units can be used.

  The cyclodextrin used in the present invention may be modified by adding a substituent or polymerizing with another substance as necessary. For example, the whole hydroxyl group or hydrogen atom of one or more hydroxyl groups of the cyclodextrin ring is substituted with an acyl group, amino group, nitro group, halogen substituent or any suitable substituent, cyclodextrin ring and an appropriate polyfunctional group A polymer formed by bonding together with an active substance.

In the present invention, it is not necessary that bamboo or cocoon or an extract component thereof is incorporated in the inclusion compound, and iodine, a burnt odor component, or the like may be incorporated. By using the clathrate compound, antibacterial durability, burning odor and coloring can be reduced.
Iodine is used to supplement antibacterial properties.

The bamboo or straw or the extract of bamboo or straw of the present invention can be used in powder form or dissolved or dispersed in various solvents, water or resin. The resin can be expected to have an effect of blocking the supply of water, oxygen and nutrients from the outside, which promotes the growth of bacteria, and an effect of suppressing the outflow of bamboo or straw or its extract components from the base material. In addition, the resin can be expected to have an effect as a viscosity modifier and a moisturizing material. When the resin is used, for example, it is used in an amount of 5 to 80% by weight with respect to bamboo or bamboo shoot or its extract component.
Examples of the resin that can be used in the present invention include acrylic acids, glycols such as polyethylene glycol, aqueous urethane resins, polyvinyl alcohol resins, polyvinyl pyrrolidone, polyethylene oxide, polyester resins having polyethylene glycol chains, and polyurethane resins having polyethylene glycol chains. And water-absorbing acrylic resins.

  Furthermore, if necessary, other antibacterial materials, various additives such as moisturizers, colorants, viscosity modifiers, emulsifiers, dispersants, ultraviolet absorbers, antioxidants, fragrances, adsorbents, etc. It may be added.

  Other antibacterial materials include silver / copper inorganic / organic antibacterial agents.

  The moisture retaining material is not particularly limited as long as it is generally hygroscopic. Representative examples include those having a hydroxyl group or a carboxylic acid group.

  Although it does not specifically limit as a coloring agent, The pigment | dye recognized as food additives, such as food pigment | dye and chlorophyll, is desirable.

Emulsifiers, dispersants, ultraviolet absorbers, antioxidants, fragrances and the like are not particularly limited.

  The filter of the present invention is applied to the surface of a base material having air permeability such as nonwoven fabric, cloth, paper, porous plastic, and the antibacterial composition of the present invention and, if necessary, an additive.・ Impregnated.

  Nonwoven fabrics used here include polyester, rayon, vinylon, polypropylene, nylon, acrylic, aramid, and other cloth-like, paper-like, and cotton-like forms, and are suitable for the spunbond method. It is what

  The antibacterial composition of the present invention can be applied to a substrate by various application methods such as brush, dipping, roller, spray, pouring, and coating machine. Examples of the coating method include dip coating, comma coating, gravure coating, curtain coating, die coating, lip coating, micro gravure coating, slot die coating, reverse coating, and kiss coating. It is also possible to use a method such as powder spraying.

The coating amount is a solid content of the antibacterial composition, and 0.1 to 150 g is preferably applied per 1 m ² of the base material. 5 to 100 g is particularly desirable. If the coating amount is too small, the sterilizing effect is reduced.

  One form of the filter of the present invention is a mask. The mask has a problem that bacteria and the like tend to propagate when used for a long time. When the antibacterial composition of the present invention is used for a mask, a normal mask use form can be applied as it is, for example, a filter made of a nonwoven fabric or cloth coated with the antibacterial composition of the present invention, paper, porous plastic, etc. A method of sandwiching it between the mask and mouth, a method of putting this filter in the pocket with a mask with a pocket, and a method of attaching an adhesive to one side of the filter and attaching it to the mask (inner bonding / outer bonding) Etc.), and the mask may be laminated with other nonwoven fabrics, cloths, nets, sheets, gauze and the like.

1 kg of kumisasa leaves was put in 1 kg of distilled water, and these were put in a pressure vessel and sealed.
The sealed container containing Kumisasa and distilled water was heated and heated until the inside reached 180 ° C. After reaching 180 ° C., the temperature was maintained as it was for 2 hours, and then the heating was stopped. After the temperature reached room temperature, the sealed container was opened and the content liquid was filtered to obtain a kumisasa extract. Since the concentration of the extract at this time was 27%, the extract was concentrated by heating to obtain a cumaisasa extract concentrate having a concentration of 50%.
This kumisasa extract concentrate and β-cyclodextrin, iodine, polyvinyl alcohol resin, ethyl alcohol, and distilled water are heated and mixed at 30 ° C. at 40: 20: 5: 15: 10: 10 (weight ratio) to obtain a kumisasa coating solution. Got.
The polyester-based non-woven fabric (80 g / cm ² ) was coated at a drying temperature of 40 ° C. for 2 minutes using a dip coater so that the kumisasa coating solution was 50 g / m ² (dry).
The odor of the obtained coated nonwoven fabric was sensory evaluated.

Comparative Example Using the Kumisasa extract concentrate used in the Examples, Kumisasa extract concentrate and β-cyclodextrin, iodine, polyvinyl alcohol resin, ethyl alcohol, and distilled water were used at 40: 20: 0: 15: 10: 10 (weight ratio). The mixture was heated and mixed at 30 ° C. to obtain a kumisasa coating solution that did not contain iodine. After that, it was applied to the nonwoven fabric in the same manner as in the Example to obtain a coated nonwoven fabric (no iodine), and the odor was similarly sensory evaluated.

Table 1
Sensory evaluation (smell)
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Example Slight Odor Comparative Example Odor
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The antibacterial composition of the present invention can be used not only for filters but also for applications that require a certain degree of antibacterial, antiviral, antifungal and the like.
For example, additives to food and drink such as drinking water and food,
Tablets, pills, mouthwashes, glazes, creams, sleeping agents, sprays, suppositories, preservatives, brushing agents, soaps, shampoos, lotions, ointments, skin adhesive films, disinfectants, bath preparations, Cosmetics or medical aids such as cosmetics,
Medical supplies such as earplugs, gloves, hats, lab coats, eyebands,
Filters such as air cleaners, coolers, vacuum cleaners, ventilation fans,
Indoor building materials such as carpets, floorboards, wallboards, wallpaper
Protective sheet for equipment, furniture and sundries, protective cover, protective plate, masterbatch, paint, ink,
Daily cloth products such as clothes, skin contact, bedding, bandages, gauze, handkerchiefs, pennants, cloths,
Examples include daily paper products such as wrapping paper, notebooks, memos, and wet tissues.

Claims (6)

An antibacterial composition comprising bamboo or straw or an extract thereof, an inclusion compound, and iodine. The antibacterial composition according to claim 1, wherein the inclusion compound is cyclodextrin. The antibacterial composition according to claim 1 or 2, wherein the extraction component of bamboo or bamboo is heat extracted from bamboo or bamboo with a solvent. Furthermore, the antibacterial composition in any one of Claims 1-3 containing resin. The filter formed by apply | coating the antimicrobial composition in any one of Claims 1-4. The filter according to claim 5, wherein the filter is a mask.