JP2006137733A - α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 - Google Patents
α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 Download PDFInfo
- Publication number
- JP2006137733A JP2006137733A JP2004331083A JP2004331083A JP2006137733A JP 2006137733 A JP2006137733 A JP 2006137733A JP 2004331083 A JP2004331083 A JP 2004331083A JP 2004331083 A JP2004331083 A JP 2004331083A JP 2006137733 A JP2006137733 A JP 2006137733A
- Authority
- JP
- Japan
- Prior art keywords
- dioxolan
- carbon dioxide
- formula
- alkylidene
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
【解決手段】 次式
【化1】
(式中のR1およびR2は、同一または別異に、水素原子または炭化水素基を示し、2つのR2は同一または別異であってもよい。)
で表わされるプロパルギルアルコール類を、含窒素環状カルベンもしくはその二酸化炭素付加物の存在下に、加圧下の二酸化炭素と反応させ、次式
【化2】
(式中のR1およびR2は前記のものを示す。)
で表わされるα−アルキリデン−1,3−ジオキソラン−2−オン類を製造する。
【選択図】なし
Description
Y.Sasaki, Tetrahedron Lett.,27,1573(1986). Y.Inoue, J.Ishikawa, M.Taniguchi, H.Hashimoto, Bull.Chem.Soc. Jpn.,60,1204(1987). K.Iritani, N.Yanagihara, K.Uchimoto, J.Org.Chem.,51,5499(1986) Y.Inoue, Y.Itoh, I.F.Yen, S.Imaizumi, J.Mol.Catal.,60,L1(1990). K.Uemura, T.Kawaguchi, H.Takayama, A.Nakamura, Y.Inoue, J.Mol.Catal.A.139,1(1999). H.Laas, A.Nissen, A.Nurrenbach, Synthesis,958(1981). H.S.Kim, J.W.Kim.S.C.Kwon, S.C.Shim, T.J.Kim, J.Organomet.Chem.,545-546,337(1997). S.C.Kwon, C.S.Cho, S.C.Shim, T.J.Kim, Bull.Korean Chem.Soc.,20,103(1999). Y. Gu, F. Shi, Y. Deng, J.Org.Chem.,69,391(2004). J.M.Joumier, J.Fourmer, C.Bruncau, P.H.Dixneuf, J.Chem.Soc.,Perkin Trans.1,3271(1991). M.Costa, et al.,J.Chem.Soc.,Chem.Commun.,1699-1700,(1996).
で表わされるプロパルギルアルコール類を、含窒素環状カルベンもしくはその二酸化炭素付加物の存在下に、加圧下の二酸化炭素と反応させ、次式
で表わされるα−アルキリデン−1,3−ジオキソラン−2−オン類を製造する。
で表わされる1種または2種以上であるものとする。
で表わされる1種または2種以上であるものとする。
オートクレーブ中、2−メチル−4−フェニル−3−ブチン−2−オール(801mg,5.0mmol)と、前記式で表わされる触媒1b(45mg,0.25mmol)を導入し、二酸化炭素を圧入(10.0MPa)したのち、100℃で攪拌する。所定の反応時間(15時間)後、反応容器を冷却し、二酸化炭素を放出する。シリカゲルカラムクロマトグラフィーなどの通常の分離操作により、(Z)−5−ベンジリデン−4,4−ジメチル−1,3−ジオキソラン−2−オンが収率75%(768mg,3.76mmol)で得られる。
<実施例2>
オートクレーブ中、2−メチル−3−ブチン−2−オール(426mg,5.0mmol)を、触媒2b(55mg,0.25mmol)の存在下で二酸化炭素の加圧下(4.5MPa)で100℃の温度において攪拌する。所定の反応時間(15時間)後、反応容器を冷却し、二酸化炭素を放出する。蒸留やシリカゲルカラムクロマトグラフィーなどの通常の分離操作により、4,4−ジメチル−5−メチレン−1,3−ジオキソラン−2−オンが収率88%(562mg,4.39mmol)で得られる。
<実施例3>
オートクレーブ中、3−エチル−5−(2−ヒドロキシエチル)−4−メチルチアゾリウム ブロマイド(63mg,0.25mmol)に1,8−ジアザビシクロ[5,4,0]−7−ウンデセン(38mg,0.25mmol)を作用させ系中で触媒5を発生させる。2−メチル−3−ブチン−2−オール(426mg,5.0mmol)を加え、二酸化炭素の加圧下(10.0MPa)で100℃の温度において攪拌する。所定の反応時間(15時間)後、反応容器を冷却し、二酸化炭素を放出する。蒸留やシリカゲルカラムクロマトグラフィーなどの通常の分離操作により、4,4−ジメチル−5−メチレン−1,3−ジオキソラン−2−オン(55mg,0.43mmol)が得られる。
Claims (4)
- 二酸化炭素を亜臨界もしくは超臨界の状態において反応させることを特徴とする請求項1のα−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004331083A JP4368289B2 (ja) | 2004-11-15 | 2004-11-15 | α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2004331083A JP4368289B2 (ja) | 2004-11-15 | 2004-11-15 | α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2006137733A true JP2006137733A (ja) | 2006-06-01 |
JP4368289B2 JP4368289B2 (ja) | 2009-11-18 |
Family
ID=36618780
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2004331083A Expired - Fee Related JP4368289B2 (ja) | 2004-11-15 | 2004-11-15 | α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JP4368289B2 (ja) |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010501019A (ja) * | 2006-08-18 | 2010-01-14 | エボニック デグサ ゲーエムベーハー | アルデヒドのカルベン触媒極性転換反応を介したα−ヒドロキシケトンの製造 |
WO2010022684A1 (zh) * | 2008-09-01 | 2010-03-04 | 南京工业大学 | 卡宾衍生物催化的环状化合物可调控开环聚合方法 |
WO2010022685A1 (zh) * | 2008-09-01 | 2010-03-04 | 南京工业大学 | 用卡宾衍生物催化制备聚乳酸的方法 |
WO2011157671A1 (de) | 2010-06-15 | 2011-12-22 | Basf Se | Verwendung von cyclischen carbonaten in epoxidharzzusammensetzungen |
JP2012501358A (ja) * | 2008-09-01 | 2012-01-19 | 南京工▲業▼大学 | 二軸スクリュ式押出機によるポリ乳酸及びその製品の製造方法 |
WO2013144299A1 (de) | 2012-03-29 | 2013-10-03 | Basf Se | Polymerisierbare alkyliden-1,3-dioxolan-2-one und deren verwendung |
EP2851403A1 (de) | 2013-09-23 | 2015-03-25 | BASF Coatings GmbH | Beschichtungsmittelzusammensetzungen und daraus hergestellte, bei niedrigen temperaturen härtbare beschichtungen und sowie deren verwendung |
EP2851379A1 (de) | 2013-09-23 | 2015-03-25 | BASF Coatings GmbH | Beschichtungsmittelzusammensetzungen und daraus hergestelllte, bei niedrigen Temperaturen härtbare Beschichtungen und sowie deren Verwendung |
US9062136B2 (en) | 2012-03-29 | 2015-06-23 | Basf Se | Polymerizable alkylidene-1,3-dioxolane-2-one and use thereof |
CN105646437A (zh) * | 2016-01-08 | 2016-06-08 | 南京林业大学 | 一种合成α—烯基缩酮的方法 |
KR20200038938A (ko) * | 2017-08-14 | 2020-04-14 | 바스프 에스이 | 시클릭 카르보네이트를 제조하는 방법 |
-
2004
- 2004-11-15 JP JP2004331083A patent/JP4368289B2/ja not_active Expired - Fee Related
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010501019A (ja) * | 2006-08-18 | 2010-01-14 | エボニック デグサ ゲーエムベーハー | アルデヒドのカルベン触媒極性転換反応を介したα−ヒドロキシケトンの製造 |
WO2010022684A1 (zh) * | 2008-09-01 | 2010-03-04 | 南京工业大学 | 卡宾衍生物催化的环状化合物可调控开环聚合方法 |
WO2010022685A1 (zh) * | 2008-09-01 | 2010-03-04 | 南京工业大学 | 用卡宾衍生物催化制备聚乳酸的方法 |
CN101665567B (zh) * | 2008-09-01 | 2011-11-23 | 南京工业大学 | 卡宾衍生物催化的环状化合物可调控开环聚合方法 |
JP2012501358A (ja) * | 2008-09-01 | 2012-01-19 | 南京工▲業▼大学 | 二軸スクリュ式押出機によるポリ乳酸及びその製品の製造方法 |
JP2012501360A (ja) * | 2008-09-01 | 2012-01-19 | 南京工▲業▼大学 | カルベン誘導体を用いたポリ乳酸の製造方法 |
WO2011157671A1 (de) | 2010-06-15 | 2011-12-22 | Basf Se | Verwendung von cyclischen carbonaten in epoxidharzzusammensetzungen |
US9062136B2 (en) | 2012-03-29 | 2015-06-23 | Basf Se | Polymerizable alkylidene-1,3-dioxolane-2-one and use thereof |
WO2013144299A1 (de) | 2012-03-29 | 2013-10-03 | Basf Se | Polymerisierbare alkyliden-1,3-dioxolan-2-one und deren verwendung |
EP2851403A1 (de) | 2013-09-23 | 2015-03-25 | BASF Coatings GmbH | Beschichtungsmittelzusammensetzungen und daraus hergestellte, bei niedrigen temperaturen härtbare beschichtungen und sowie deren verwendung |
EP2851379A1 (de) | 2013-09-23 | 2015-03-25 | BASF Coatings GmbH | Beschichtungsmittelzusammensetzungen und daraus hergestelllte, bei niedrigen Temperaturen härtbare Beschichtungen und sowie deren Verwendung |
US9920215B2 (en) | 2013-09-23 | 2018-03-20 | Basf Coatings Gmbh | Coating material compositions and low-temperature-curable coatings produced therefrom, and use thereof |
US9951245B2 (en) | 2013-09-23 | 2018-04-24 | Basf Coatings Gmbh | Coating material compositions and low-temperature-curable coatings produced therefrom, and use thereof |
CN105646437A (zh) * | 2016-01-08 | 2016-06-08 | 南京林业大学 | 一种合成α—烯基缩酮的方法 |
KR20200038938A (ko) * | 2017-08-14 | 2020-04-14 | 바스프 에스이 | 시클릭 카르보네이트를 제조하는 방법 |
JP2020535116A (ja) * | 2017-08-14 | 2020-12-03 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | 環状カーボネートの製造方法 |
JP7184873B2 (ja) | 2017-08-14 | 2022-12-06 | ビーエーエスエフ ソシエタス・ヨーロピア | 環状カーボネートの製造方法 |
KR102605180B1 (ko) | 2017-08-14 | 2023-11-24 | 바스프 에스이 | 시클릭 카르보네이트를 제조하는 방법 |
Also Published As
Publication number | Publication date |
---|---|
JP4368289B2 (ja) | 2009-11-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Weidner et al. | Direct Catalytic Asymmetric Aldol Reaction of an α‐Azido Amide | |
Kang et al. | Highly enantioselective and diastereoselective cycloaddition of cyclopropanes with nitrones and its application in the kinetic resolution of 2‐substituted cyclopropane‐1, 1‐dicarboxylates | |
Hamashima et al. | Highly enantioselective fluorination reactions of β-ketoesters and β-ketophosphonates catalyzed by chiral palladium complexes | |
Zhong et al. | New β-amino alcohols with a bicyclo [3.3. 0] octane scaffold in an asymmetric Henry reaction | |
Kamlar et al. | Formal [3+ 2] cycloaddition of vinylcyclopropane azlactones to enals using synergistic catalysis | |
Kano et al. | Synthesis of a biphenyl-based axially chiral amino acid as a highly efficient catalyst for the direct asymmetric aldol reaction | |
Wang et al. | A novel proline‐valinol thioamide small organic molecule for a highly enantioselective direct aldol reaction | |
Gu et al. | A new class of efficient poly (ethylene-glycol)-supported catalyst based on proline for the asymmetric Michael addition of ketones to nitrostyrenes | |
Murai et al. | Rhenium‐Catalyzed Construction of Polycyclic Hydrocarbon Frameworks by a Unique Cyclization of 1, n‐Diynes Initiated by 1, 1‐Difunctionalization with Carbon Nucleophiles | |
Yoshida | Development of palladium-catalyzed transformations using propargylic compounds | |
JP4368289B2 (ja) | α−アルキリデン−1,3−ジオキソラン−2−オン類の製造方法 | |
Luo et al. | Highly efficient asymmetric Michael reaction of aldehydes to nitroalkenes with diphenylperhydroindolinol silyl ethers as organocatalysts | |
Moreau et al. | Catalytic asymmetric synthesis of nitrocyclopropane carboxylates | |
Nie et al. | Chiral bifunctional thiourea-catalyzed enantioselective aldol reaction of trifluoroacetaldehyde hemiacetal with aromatic ketones | |
Miura et al. | Direct asymmetric aldol reactions in water with a β-aminosulfonamide organocatalyst | |
Chen et al. | Enantioselective synthesis of chiral phosphonylated 2, 3-dihydrofurans by copper catalyzed asymmetric formal [3+ 2] cycloaddition of propargylic esters with β-keto phosphonates | |
Ohshima et al. | Catalytic asymmetric epoxidation of α, β-unsaturated carboxylic acid imidazolides and amides by lanthanide–BINOL complexes | |
Liu et al. | Cooperative N-heterocyclic carbene/nickel-catalyzed hydroacylation of 1, 3-dienes with aldehydes in water | |
Wettergren et al. | Ruthenium‐Catalyzed Enantioselective Reduction of Electron‐Rich Aryl Alkyl Ketones | |
Deng et al. | Iodoarene-catalyzed oxyamination of unactivated alkenes to synthesize 5-imino-2-tetrahydrofuranyl methanamine derivatives | |
Miura et al. | Direct asymmetric aldol reactions in brine using novel sulfonamide catalyst | |
Kumagai | Development of atom-economical catalytic asymmetric reactions under proton transfer conditions: construction of tetrasubstituted stereogenic centers and their application to therapeutics | |
Tokunaga et al. | Copper-catalyzed oxidative cleavage of carbon–carbon double bond of enol ethers with molecular oxygen | |
Kuninobu et al. | Rhenium‐and Manganese‐Catalyzed Insertion of Alkynes into a Carbon–Carbon Single Bond of Cyclic and Acyclic 1, 3‐Dicarbonyl Compounds | |
Zhou et al. | Highly enantioselective synthesis of syn-aldols of cyclohexanones via chiral primary amine catalyzed asymmetric transfer aldol reactions in ionic liquid |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20090106 |
|
A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20090309 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20090818 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20090825 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 4368289 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120904 Year of fee payment: 3 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120904 Year of fee payment: 3 |
|
S531 | Written request for registration of change of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313531 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120904 Year of fee payment: 3 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120904 Year of fee payment: 3 |
|
S631 | Written request for registration of reclamation of domicile |
Free format text: JAPANESE INTERMEDIATE CODE: R313631 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20120904 Year of fee payment: 3 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
FPAY | Renewal fee payment (event date is renewal date of database) |
Free format text: PAYMENT UNTIL: 20130904 Year of fee payment: 4 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
S533 | Written request for registration of change of name |
Free format text: JAPANESE INTERMEDIATE CODE: R313533 |
|
R350 | Written notification of registration of transfer |
Free format text: JAPANESE INTERMEDIATE CODE: R350 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
LAPS | Cancellation because of no payment of annual fees |