JP2006083116A - Skin external preparation - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a skin internal preparation having an effect of imparting flexibility to the skin without rendering its spreadability heavy in the skin external preparation containing an ester oil composed of a branched chain fatty acid and a branched chain alcohol. <P>SOLUTION: By using an ester oil composed of a branched chain fatty acid and a branched alcohol together with meadow-foam oil, the skin external preparation which has light spreadability and excels in the effect of skin flexibility effect on its application to the skin can be obtained. As the ester oil composed of a branched chain fatty acid and a branched chain alcohol, at least one kind selected from the esters of 5-20C branched fatty acids with 4-20C branched alcohols is preferably used. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to an external preparation for skin that is lightly stretched when applied to the skin and has an excellent skin softening effect.

  It has been known that an external preparation for skin containing a silicone oil such as dimethylpolysiloxane has a light and easy-to-use feeling with little elongation and no stickiness. However, the external preparation for skin containing silicone oil sometimes dulls the skin over time after use and gives a bulky feel. Therefore, in order to lighten the elongation when applied to the skin, an ester oil composed of a branched chain fatty acid and a branched chain alcohol has been used. (See Non-Patent Document 1)

Kyoko Kurata et al., Cosmetics Handbook, Nikko Chemicals, 1996, 48-49

    However, ester oils composed of branched chain fatty acids and branched chain alcohols have a problem in that they have poor skin softening effect and remain stretchy after use compared to straight chain oils. Accordingly, in the present invention, an external preparation for skin containing an ester oil composed of a branched chain fatty acid and a branched chain alcohol, and to provide a skin external preparation having an effect of imparting flexibility to the skin without increasing the elongation. It was.

  As a result of various studies to solve the above-mentioned problems, by using together ester oil composed of branched chain fatty acid and branched chain alcohol and Meadowfoam oil, the elongation when applied to the skin is light and the skin softening effect is excellent. It was found that an external preparation for skin was obtained, and the present invention was completed.

  A topical skin preparation formulated with a combination of an ester oil composed of a branched chain fatty acid and a branched chain alcohol and Meadowfoam oil is lightly stretched when applied to the skin and has an excellent skin softening effect.

  In the present invention, the ester oil composed of a branched chain fatty acid and a branched chain alcohol is not particularly limited as long as it can be used for an external preparation for skin. For example, a branched chain fatty acid having 5 to 20 carbon chains and 4 carbon chains. ~ 20 branched chain alcohol esters can be used. Examples of the branched chain fatty acid having 5 to 20 carbon atoms include isopentanoic acid having 5 carbon chains (isovaleric acid), isohexanoic acid having 6 carbon atoms (isocaproic acid), isoheptanoic acid having 7 carbon atoms (isoenanthic acid), and 8 carbon atoms. Isooctanoic acid (isocaprylic acid), carbon number 9 isononanoic acid (isopelargonic acid), carbon number 10 isodecanoic acid (isocapric acid), carbon number 11 isoundecanoic acid, carbon number 12 isododecanoic acid (isolauric acid), C13 isotridecanoic acid (isotridecylic acid), C14 isotetradecanoic acid (isomyristic acid), C15 isopentadecanoic acid (isopentadecyl acid), C16 isohexadecanoic acid (isopalmitic acid) , Carbon number 17 isoheptadecanoic acid (isomargaric acid), carbon number 18 isooctadecanoic acid ( Sosutearin acid), Isononadekan acid (Isononadeshiru acid 19 carbon atoms), Isoikosan acid 20 carbon atoms (isoarachic acid). Examples of the branched chain alcohol having 4 to 20 carbon atoms include isobutanol having 4 carbon atoms (isobutyl alcohol), isopentanol having 5 carbon atoms (isoamyl alcohol), isohexanol having 6 carbon atoms (isocaproyl alcohol), carbon number 7 isoheptanol, C8 isooctanol (isocaprylyl alcohol), C9 isononanol, C10 isodecanol (isocapryl alcohol), C11 isoundecanol, C12 iso Dodecanol (isolauryl alcohol), carbon 13 isotridecanol, carbon 14 isotetradecanol (isomyristyl alcohol), carbon 15 isopentadecanol, carbon 16 isohexadecanol (iso Cetyl alcohol), 17-carbon isoheptadecano Le, isooctadecanol having 18 carbon atoms (isostearyl alcohol), isononyl Na octadecanol 19 carbon atoms, Isoikosanoru of 20 carbon atoms (b SOARER kill alcohol) are exemplified. As such ester oil, it is possible to use one or more kinds selected from isocetyl isostearate, isostearyl isopentanoate, octyldodecyl isopentanoate, isononyl isononanoate, isotridecyl isononanoate, isocetyl isooctanoate as a skin external preparation. It is preferable from the point of the lightness of elongation at the time of mix | blending.

  The meadow foam oil used in the present invention is a triglyceride extracted from meadow foam seeds, and it is preferable to use the one subjected to the adsorption purification treatment from the viewpoint of odor and oxidation stability.

  The external preparation for skin according to the present invention can be provided in various dosage forms such as liquids, emulsions, gels, creams, ointments and the like.

  In addition, the skin external preparation according to the present invention includes, in addition to ester oils composed of branched chain fatty acids and branched chain alcohols, and meadow foam oil, oil components, surfactants, and moisturizers as long as the usability of the present invention is not impaired. , Pigments, ultraviolet absorbers, perfumes, antibacterial and antifungal agents, and other general pharmaceutical and cosmetic raw materials, anti-inflammatory agents, whitening agents, cell activators, and other physiologically active ingredients.

  Further, the features of the present invention will be described in detail by way of examples. First, an emulsion was prepared by a conventional method according to the formulation shown in Table 1, and sensory evaluation was performed by a panelist specializing in sensory evaluation. The evaluation was “◎: very good”, “○: good”, “△: normal”, “×: not good” for lightness of elongation at the time of use, skin softening effect, and lack of dryness after 2 hours. The results are shown in Table 1.

  As shown in Table 1, the examples of the present invention have the same elongation as that of Comparative Example 1 in which dimethylpolysiloxane is blended, and the skin softening effect is stearic acid which is an ester of a linear fatty acid and a branched alcohol. It was about the same as Comparative Example 2 containing isocetyl.

[Example 2] Oil
(1) Isostearyl neopentanoate 47.0 (wt%)
(2) Isocetyl isostearate 47.0
(3) Meadowfoam oil 5.9
(4) Vitamin E 0.1
Manufacturing method: Mix and homogenize all ingredients.

[Example 3] Oil-in-water cream (1) Beeswax 5.00 (wt%)
(2) Cetanol 5.00
(3) Reduced lanolin 7.00
(4) Isostearyl neopentanoate 27.50
(5) Meadow foam oil 2.00
(5) Glyceryl fatty acid ester 4.00
(6) Lipophilic glyceryl monostearate 2.00
(7) Polyoxyethylene (20E.O.) sorbitan
Monostearate 5.00
(8) Stearyl glycyrrhetinate 0.25
(9) Retinol 0.20
(10) Propylene glycol 5.00
(11) Methyl paraoxybenzoate 0.10
(12) Purified water 36.95
Production method: The oil phase components (1) to (9) are mixed and dissolved to 75 ° C. On the other hand, (10) to (12) are mixed and dissolved, and heated to 75 ° C. Next, the oil phase component is added to the aqueous phase component and pre-emulsified, and then uniformly emulsified with a homomixer and cooled.

  About Example 2, 3, as a result of performing usability evaluation, the elongation was light and the usability was excellent in skin softening effect.

Claims (3)

An external preparation for skin comprising an ester oil composed of a branched chain fatty acid and a branched chain alcohol and a meadow foam oil. The ester oil comprising a branched chain fatty acid and a branched chain alcohol is one or more selected from esters of a branched chain fatty acid having 5 to 20 carbon chains and a branched chain alcohol having 4 to 20 carbon chains. Item 1. An external preparation for skin according to Item 1. The ester oil comprising a branched chain fatty acid and a branched chain alcohol is one or more selected from isocetyl isostearate, isostearyl isopentanoate, octyldodecyl isopentanoate, isononyl isononanoate, isotridecyl isononanoate, and isocetyl isooctanoate. The external preparation for skin according to claim 1.