JP2006022074A - Antimicrobial coating film and industrial product - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide antimicrobial coating film effective to microbes abundantly living in the life environment, especially to fungi, and also affecting human health little, in other words, to provide a highly safe antimicrobial coating film. <P>SOLUTION: The antimicrobial coating film essentially comprises a coating resin and a water-based extract of either one plant selected from the following: Myrtaceae eucalyptus plant branches/leaves, Zingiberaceae kaempferia plant rhizome, Laminaceae isodon eriocalyx (Dunn)Kuds terrestrial whole plant, Laminaceae Labiatae soutellaria baicalensis Georg. plant rhizome, Usneaceae usnea longissima Ach. whole plant, Anacardiaceae pistacia plant bark and/or branches/leaves and Compositae taikinngiku whole plant. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to an antimicrobial coating film for suppressing the growth of microorganisms existing in a living environment or killing microorganisms. The present invention also relates to an antimicrobial coating effective for improving the cleanliness of the living environment, preventing deterioration of building materials, preventing allergies of residents, and the like.

When wrinkles occur in building materials used in the living environment, the appearance is impaired and the strength of the building materials is deteriorated. In addition, sputum can be a source of allergies and can compromise the health of residents. On the other hand, the “antibacterial boom” that applies antibacterial treatment to daily commodities such as writing instruments has been added to the recent consumer orientation. Therefore, it is desired to apply antibacterial treatment to various materials around us. In order to meet such a demand, various antibacterial compositions for forming an antibacterial coating film on the surface of a material have been developed (see, for example, Patent Document 1).
JP 2000-154339 A

  Due to recent consumer preference for natural products, antimicrobial coatings are also demanded to use materials that have been used in nature for many years. An object of the present invention is to provide an antimicrobial coating film that is effective against microorganisms that inhabit many living environments, particularly fungi, and has little influence on the human body, in other words, high safety.

In the present invention, Myrtaceae (Myrtaceae) Yuukarinoki genus (Eucalyptus) plant foliage, Zingiberaceae (Zingiberaceae) Ban'ukon genus (Kaempferia) rhizome, Labiatae (Laminaceae (Labiatae)) Isodon genus (Isodon) aboveground plant Whole plant body, Lamaceae (Labiatae) Rhizome ( Scutellaria ) plant rhizome, Salneaceae ( Usneaceae ) Salogase ( Usnea ) plant whole plant, Urushiaceae ( Anacardiaceae ) Lansymbol ( Pistacia ) bark And an aqueous extract of at least one plant selected from the group consisting of all plants of the branches and leaves and Compositae Senecio plants.

Each aqueous extract of the branches and leaves of the genus Eucalyptus and the rhizomes of the genus Vanculone has antibacterial activity against gram-negative bacteria typified by Escherichia coli . All plants of the above-ground part of the Lamiaceae genus Isodon, the rhizome of the Lamiaceae genus, the alligator of the genus Solanumaceae, the bark and its branches and leaves of the Ranunculaceae genus, and the all plants of the asteraceae genus Each water extract of the body has antibacterial performance against gram positive bacteria represented by Staphylococcus aureus .

Also in the present invention, Labiatae (Labiatae) Isodon genus (Isodon) whole plants above-ground plant, Labiatae (Labiatae) Scutellaria (Scutellaria) rhizome, Usnea family (Usneaceae) Usnea sp (Usnea) Plant whole plants, organic solvent of at least one plant selected from Anacardiaceae (Anacardiaceae) Ranshinboku genus (Pistacia) bark and branches, as well as polygonaceae (Polygonaceae) rhubarb genus (Rheum) the group consisting of rhizome of a plant plant extracts Things are used. These organic solvent extracts have antibacterial performance against gram-positive bacteria represented by Staphylococcus aureus .

  The plant body used in the present invention has long been recognized for its pharmacological action and has been used as a traditional Chinese medicine for the treatment of diseases, or its action has been passed down as a folk medicine. In the following, specific examples of these plants are given and their uses are described.

Eucalyptus globulus Labill. , Eucalyptus smithii RT Baker , Eucalyptus citriodora Hook. Etc. are mentioned as a plant belonging to the genus Eucalyptus . For example, Chinese-made Eucalyptus globulus Labill. Is used as a topical medicine for the treatment of neuralgia or for the treatment of bronchitis by inhalation of steam.

Plants belonging to the genus Isodon genus include Isodon eriocalyx (Dunn) Kuds , Isodon longitubus , Isodon shikokianus var. Intermedius , Isodon umbrosus , Isodon umbrosus var. Excisinflexus . Isodon eriocalyx (Dunn) Kuds is used for colds, sore throat, gastritis, hepatitis, tonsillitis, mastitis, early cancer, menopause , bruises, joint pain, snakes and insect bites .

Plants belonging to the genus Lamiaceae include Scutellaria baicalensis Georg. , Scutellaria cavaleriei , Scutellaria hebeclada , Scutellaria mairei , Scutellaria taquetii , Scutellaria thieretii , Scutellaria vaniotiana and Scutellaria veronicifolia . Scutellaria baicalensis Georg. Is used to prevent scarlet fever and to treat acute enteritis, diarrhea, and acute and chronic hepatitis.

An example of a plant belonging to the genus Banturmeric of the family Ginger is Kaempferia galanga L .. Van turmeric is used for treatment of toothache as a topical medicine in addition to decoction for abdominal pain and cold and vomiting.

Usnea longissima Ach. , Usnea pangiana , Usnea rubescens , Usnea diffracta, etc. are mentioned as plants belonging to the genus Sarogase . Nagasa Ogase ( Usnea longissima Ach. ) Is used for pulmonary tuberculosis and various inflammations, and is used as a spray for various ulcers. Recently, however, it is often imported exclusively as a raw material for perfumes and is rarely used for medicinal purposes.

An example of a plant belonging to the genus Ranshinboku is Ranshinboku ( Pistacia weinmannifolia J. Poisson ex Franch ). Lanshinboku is said to be used for symptoms such as diarrhea, dermatoses, and sores, but it is not used in Japan.

Examples of the plant belonging to the Asteraceae ragwort species, Senecio scandens Buch.-Ham., Senecio madagascariensis Poiret, Senecio rowleyanus, Senecio macroglossus, Senecio nemorensis, Senecio anteuphorbium, Senecio glaberrimus, Senecio keniodendron, Senecio platyphylloides, Senecio hybridus, Senecio fremontii, Senecio integrifolius subsp. fauriei and Senecio vulgaris . Senecio scandens Buch.-Ham. Is used for upper respiratory tract infection, tonsillitis, sore throat, pneumonia, ocular conjunctivitis, dysentery, enteritis, appendicitis, acute lymphangitis, eczema, allergic dermatitis, etc. . However, it is not used medicinally in Japan.

Examples of the plant belonging to the genus Rhiumaceae include Rheum officinale Baill. , Rheum palmatum L. , Rheum tanguticum Maxim. , Rheum coreanum Nakai , Rheum rhaponticum Linn. , Rheum undulatum L. and the like. Daio ( Rheum officinale Baill. ) Is used as a colonic armpit, an anti-inflammatory stomachic medicine and the like.

  As described above, the plant used in the present invention is used mainly for the treatment of diseases and the like and is only used as a symptomatic treatment. There are few research reports on the antimicrobial action, such as antibacterial action, of these plant components. For example, Japanese Patent Application Laid-Open No. 11-80012 discloses that a polar organic solvent extract of branches and leaves of the genus Eucalyptus is effective against ringworm, acne or MRSA (methicillin resistant Staphylococcus aureus). However, as will be described later, for gram negative, the water extract of the present invention has higher antibacterial performance than the polar organic solvent extract disclosed in the publication.

  The antimicrobial coating film according to the first aspect of the present invention comprises a plant of leaves of Eucalyptus family, an alligator plant of Rhizoaceae, a curcuma plant, a rhododendron plant, a rhododendron mangrove plant, a rhododendron family, a plant of the family Salamander, Contains at least a water extract of at least one plant selected from the group consisting of the whole plant, the urchinaceae Ranshinboku bark and its branches and leaves, and the total plant of the Asteraceae plant, and typically further contains a paint resin To do.

  The antimicrobial coating film according to the second aspect of the present invention comprises all plant bodies of Lamiaceae Manshuhiokikoshi plant, rhizome family Rhizome Rhizome, Salogaceae Nagasaruogase plant whole plant, Urushi family Ranshinboku plant bark and its branches and leaves And at least one organic solvent extract of at least one plant selected from the group consisting of rhizobia rhizomes, and typically further contains a coating resin.

  In the present specification, the “plant” includes not only the whole plant (total plant) but also a part thereof, such as branches, rhizomes, and bark. “Microorganisms” include bacteria, filamentous fungi, yeast, variant bacteria, unicellular algae, protozoa, and viruses. The “antimicrobial coating film” is a coating film for suppressing the growth of microorganisms or killing microorganisms, and is formed, for example, by applying an antibacterial paint or an antibacterial spray.

  The “water extract” is an extract obtained by extracting an active ingredient from a plant body by steam distillation or immersion, and the “organic solvent extract” is a plant extract in an organic solvent (including a mixed solvent of water and an organic solvent). It is an extract obtained by immersing and extracting an active ingredient from a plant body. In addition, the water extract and the organic solvent extract may be collectively referred to as “plant extract”.

  An organic solvent extract is an extract extracted using an organic solvent or a mixed solvent of water and an organic solvent. Examples of the organic solvent include ethyl alcohol, methyl alcohol, acetone, chloroform, benzene, methylene chloride and the like. Examples of the mixed solvent of water and organic solvent include a mixed solvent of water and acetone and a mixed solvent of water and ethyl alcohol. The mixing weight ratio of water and organic solvent is 5 to 95 parts by weight of water: 95 to 5 parts by weight of organic solvent, preferably 15 to 85 parts by weight of water: 85 to 15 parts by weight of organic solvent, more preferably 25 to 75 parts of water. Part by weight: 75 to 25 parts by weight of an organic solvent.

  As a method for extracting an active ingredient from a plant body, a generally used method may be used. For example, there are a method of immersing a raw plant part in a solvent for a long time, a method of performing extraction while heating and stirring at a temperature below the boiling point of the solvent, and obtaining an extract by filtration. It is desirable to prepare the extract by concentrating the extract using an evaporator or spray drying method.

  The antimicrobial coating film according to the first and second aspects of the present invention may contain a resin contained in an aqueous paint such as a water-soluble resin paint or a synthetic resin emulsion paint as a paint resin. The water-soluble resin paint is a paint using a water-soluble resin forming a water-soluble colloid, for example, carboxymethyl cellulose or polyvinyl alcohol as a paint resin (hereinafter also referred to as a paint binder). The synthetic resin emulsion paint is a paint in which a synthetic resin emulsion obtained by emulsion polymerization or the like is dispersed in water as a paint binder. As the synthetic resin, acrylic resin, polyester resin, epoxy resin, urethane resin, silicon resin, fluorine resin, phenol resin, alkyd resin, amino alkyd resin, urea resin, unsaturated resin, vinyl resin and the like are generally used. Specific examples of the coating resin having high hydrophilicity include polyvinyl alcohol, carboxymethyl cellulose, epoxy resin, urethane resin, and polyester resin.

  The antimicrobial coatings according to the first and second aspects of the present invention are typically formed by applying an antimicrobial paint onto a substrate and drying. The antimicrobial paint includes at least a plant extract according to the present invention, a paint resin, and a coating solvent for dispersing the plant extract and the paint resin according to the present invention. In addition, a coating solvent refers to the solvent for forming an antimicrobial coating film, and distinguishes it from the solvent for extracting a plant body.

  The antimicrobial paint can be prepared by mixing a dispersion in which at least one plant extract is dispersed and a paint containing a paint resin and a coating solvent. Alternatively, an antimicrobial paint may be prepared by dispersing at least one plant extract in a paint containing a paint resin and a coating solvent.

  The coating solvent for dispersing the plant body extract is selected from the solubility of the plant body extract and the compatibility with the coating resin. Specifically, as a coating solvent for dispersing the plant extract, one kind of solvent selected from the group consisting of water, methyl alcohol, ethyl alcohol, isopropyl alcohol and acetone, or a combination of a plurality of kinds of solvents is combined. A solvent can be suitably used.

  The solvent for dispersing the plant extract and the solvent contained in the paint are typically the same type of solvent, but both solvents may be different types of solvents. For example, the solvent for dispersing the plant extract may be water, and the solvent contained in the paint may be a mixed solvent of water and ethyl alcohol.

  The plant extract is applied in an amount of 1 to 500 parts by weight, preferably 1 to 100 parts by weight, more preferably 1 to 50 parts by weight, based on 100 parts by weight of the solid content of the coating resin. It may be contained in the film.

  The antimicrobial coating film according to the first and second aspects of the present invention may not contain a paint resin. In other words, in the present specification, the “antimicrobial paint” includes a paint in which a plant extract and a coating solvent are mixed and dispersed.

The antimicrobial coating film according to the first and second aspects of the present invention may further contain an inorganic carrier. It is preferable that the inorganic carrier is mainly composed of a porous inorganic oxide such as silica gel. The inorganic carrier may be a particulate powder having a silanol group on the surface. The inorganic carrier desirably has a specific surface area of 300 m ² / g or more, preferably 500 m ² / g or more, from the viewpoint of the adsorptivity of the extract to the carrier. In addition, from the viewpoint of unevenness of the coating film surface after coating, it is desirable that the particle size is 50 μm or less, preferably 1 μm or more and 30 μm or less.

  The specific surface area is measured according to the Brunauer-Emmett Taylor (BET) method described in “The journal of the American Chemical Society”, Vol. 60, page 309, February 1938, or the BET method based on the measurement of gas adsorption. be able to. The particle size of the particulate powder can be measured using an optical microscope, a scanning electron microscope, or a sedimentation method.

  The inorganic carrier may be a particulate powder composed of an intercalation compound. Examples of interlayer compounds include hydrotalcite compounds and smectites compounds. The hydrotalcite compound is represented by the following general formula.

[M ²⁺ _1-x M ³⁺ _x (OH) ₂ ] _{x +} [A ^n- _{x / n} · yH ₂ O] _x-
(Magnesium wherein, M ²⁺ is nickel, cobalt, manganese, divalent metal ions such as zinc, M ³⁺ is aluminum, iron, manganese, trivalent metal ions such as chromium, A ^n-hydroxyl group, chlorine, (It is an n-valent anion such as a nitrate group, a carbonate group or a sulfate group.)

Hydrotalcite compounds have the general formula _{A 6 B 2 (CO 3)} (OH) 16 · 4H 2 O [where, A = Mg, Ni; B = Al, Cr 3+, Fe 3+, Mn 2+, Co ³⁺ ] and trigonal carbonate mineral. Examples of the carbonate mineral include hydrotalcite represented by Mg ₆ Al ₂ (CO ₃ ) (OH) ₁₆ · 4H ₂ O. Other examples include combiinite, desautelsite, iowaite, pyrorite, reevesite, stichtite, takovite.

The smectite compound has the general formula X _0.3 Y _2-3 Z ₄ O ₁₀ (OH) ₂ .nH ₂ O [where X (exchangeable ion) = Ca / 2, Li, Na; Y = Al, Cr ³⁺ , Cu ²⁺ , Fe ²⁺ , Fe ³⁺ , Li, Mg, Ni, Zn; Z = Al, Si]. Examples of the silicate mineral include montmorillonite represented by (Na, Ca) _0.3 (Al, Mg) ₂ Si ₄ O ₁₀ (OH) ₂ .nH ₂ O. Other examples include aliettite, beidellite, hectorite, nontronite, saponite, sauconite, stevensite, swinefordite, volkonskoite, yakhontovite.

  The antimicrobial coating film according to the first and second aspects of the present invention comprises a coating resin of 1 to 30 parts by weight, an inorganic carrier of 10 to 50 parts by weight, and 49 to 89 parts by weight. Less than or equal to the present extract.

  The antimicrobial coating film according to the first and second aspects of the present invention comprises other antibacterial or bactericidal agents, repellents, efficacy enhancers, insect repellents, attractants, deodorants, UV inhibitors (UV absorbers and (Including deterioration inhibitors due to ultraviolet rays), antioxidants, thickeners, stabilizers, brighteners, pigments, dyes, fillers, and the like. Further, it may contain a synthetic anti-epileptic agent.

  Antimicrobial coatings containing plant extracts typically include extracts other than active ingredients. Both the active ingredient and the other extracts are considered to have a high ability to assimilate microorganisms, so that there is a risk that decay will proceed. The decay of the extract may not only reduce the active ingredient, but also attract pests.

  Therefore, it is desirable that the antimicrobial coating film of the present invention contains a silver antibacterial agent and / or a natural antibacterial agent in order to prevent the decay of the plant body extract. The silver-based antibacterial agent may contain a carrier on which a silver complex and / or silver ions are supported. Examples of the carrier carrying the silver complex include silica gel carrying a thiosulfato silver complex (trade name: Amenitop, manufactured by Matsushita Electric Industrial Co., Ltd.). Examples of the carrier on which silver ions are supported include silver ion-supported zeolite, silver ion-supported phosphate, and silver ion-supported glass. At least one kind of plant extract may be adsorbed and supported on these carriers.

As natural antibacterial agents, catechins, wasabi (Brassicaceae Eutrema japonica ) extract, Sosou bamboo (Poaceae Phyllostachys pubescens ) extract and the like can be used. Moreover, you may use the synthetic product of the active ingredient contained in a natural type antibacterial agent. For example, a synthetic product of allyl isothiocyanate contained in the horseradish extract may be used.

  The addition amount of the silver antibacterial agent or the natural antibacterial agent is preferably 0.1 parts by weight or more and 50 parts by weight or less with respect to 100 parts by weight of the total solid content. Furthermore, the anti-degradability of the antimicrobial coating film against fungi can be improved by using a synthetic anti-epileptic agent to exhibit anti-epileptic performance.

  The present invention also provides industrial products according to the following first to fourth aspects. The industrial product according to the first aspect of the present invention includes an air quality adjusting electrical device equipped with an air filter. Examples of the air quality adjusting electrical device include an air cleaner, an air conditioner, a humidifier, and a vacuum cleaner. The air filter is a woven fabric, a non-woven fabric, or a combination thereof, and the antimicrobial coating film of the present invention is formed at least at the fiber intersection.

  The industrial product according to the second aspect of the present invention includes a sheet on which the antimicrobial coating film of the present invention is printed or coated. The antimicrobial coating film is formed by printing or coating the antimicrobial paint on the sheet surface in various patterns (for example, dot shape, stripe shape, matrix shape, etc.). The surface area of the antimicrobial coating is 50% or more, preferably 90% or more of the surface area of the sheet. Examples of the printing or coating method include spray coating, screen printing, roll coater method, gravure printing, letterpress printing, and soaking method.

  The sheet is typically made of paper, cloth, metal or synthetic resin, and has a single layer or multilayer structure. A sheet | seat is provided in the predetermined location of industrial products. For example, a place where the user's fingers frequently come in contact, or a wet place where there is a possibility of bacterial growth. Specifically, a control panel such as a touch panel, an input or control device interface panel, a push button panel, or a floor below. Moreover, the wallpaper for which the sheet | seat by which the antimicrobial coating film of this invention was printed or coated on the surface is affixed or mounted | worn on a wall surface may be sufficient.

  The industrial product according to the third aspect of the present invention is an electrical device in which the antimicrobial coating film of the present invention is formed on a casing, a component base material, or a circuit board (typically a printed wiring board). The antimicrobial coating is printed or coated with an antimicrobial coating on one or both sides of the casing, component base or circuit board, or the casing, component base or circuit board is impregnated with the antimicrobial coating. Formed by. Examples of the electrical equipment include cooking electrical appliances, home electrical appliances, security equipment, communication equipment, office equipment, and toiletry equipment. Specifically, refrigerator, wine cellar, freezer, range, jar pot, mixer, juicer, food processor, hot plate, grill pan, fish roaster, cooking heater, mochi machine, cold / hot water bottle, electric water heater, alkaline ionized water Cooker, jar rice cooker, coffee maker, coffee mill, home bakery, water purifier, mineral water conditioner, system kitchen, dishwasher, dish dryer, garbage disposal machine, washing machine, clothes dryer, vacuum cleaner, ion Washing water maker, futon dryer, polisher, bath buzzer, electric bucket, shredder, dehumidifier, dehumidifier dryer, air purifier, hot water washing toilet seat, air conditioning air conditioner, oil stove, electric stove, electric fan, humidifier, electric blanket, Hot water room heater, oil far red heater, electric air heater, oil heater, oil fan heater Oil heater, gas heater, gas water heater, electric water heater, ventilation fan, underfloor dryer, heat pump water heater, shaver, hair removal / hair removal equipment, dryer, electric toothbrush, massage chair, lighting equipment, wiring equipment, report Terminal device, flame detector, smoke detector, pencil sharpener, desk cleaner, TV, video, video camera, audio, DVD (Digital Versatile Disc) player, personal computer, personal computer peripherals, fax machine, electronic musical instrument, telephone, mobile phone, etc. Is exemplified.

  The industrial product by the 4th aspect of this invention is equipped with the member in which the antimicrobial coating film of this invention was formed. The antimicrobial coating is formed by printing or coating an antimicrobial paint on a member or impregnating the member. The member is typically a base made of paper, metal or synthetic resin. The shape of a member will not be specifically limited if it is a shape suitable for the industrial product with which a member is provided. For example, an antimicrobial coating film can be formed on the surface by applying an antimicrobial paint to a sheet, a tube, a molded product having a curved surface, or the like.

  The industrial product according to the fourth aspect of the present invention includes various members and equipment. For example, building materials, stationery, clothing, accessories, home gardening materials, office equipment, interior materials, exterior materials, vending machines, automobile parts, electrical product parts, transportation equipment, furniture, household goods, cooking equipment, medical products, Includes nursing care facilities.

  Examples of building materials include wallpaper, underfloor sheets, handrails, and the like. Examples of stationery include fountain pens, mechanical pencils, ballpoint pens, pencil cases, document boxes, carry cases, document holders, underlays, mouse pads, card folders, bags, toys, infant supplies, musical instruments, and the like. Examples of clothing include underwear, socks, cutter shirts, towels, sheets, bedspreads, nightclothes, pillows, futons, futon cotton, beds, mattresses and the like. Examples of the accessory include a belt, glasses, a watch article, gloves, an apron, and a denture-related instrument.

  Examples of home gardening materials include multi-films, chilled rice cakes, greenhouse films, fruit-covered bags, attracting strings, support pillars, and the like. Examples of office equipment include document storage, equipment storage, and lockers. Examples of interior members include cupboards, underfloor storage, animal cages, curtains, blinds, and the like. Examples of the exterior member include a waterproof sheet, a fence, and a screen door.

  Examples of the automobile parts include a handle, a seat member, a vehicle interior cleaning product, a car air conditioner, an in-vehicle refrigerator, and an in-vehicle AV (audiovisual) device. Examples of the electrical product parts include parts used in the above-described electrical equipment. Examples of the traffic-related device include a suspension ring, an ETC (automatic toll collection system) in-vehicle device, an ETC card, a train communication device (in-vehicle public telephone), and the like. Examples of the furniture include a cupboard and a bed. Examples of daily miscellaneous goods include bathing products, toiletries, toothbrushes, barber / beauty products, kitchenware, tableware, food and drink, one-way containers, returnable bottles, storage containers, and the like. Examples of the cooking device include a rice cooker, a mixer, a refrigerator, a wine cellar, a serving tray, a rice bran, and a seasoning server. Examples of medical products include cosmetics, adhesive bandages, contact lens supplies, masks, and the like. Examples of medical welfare equipment include nursing care items, walking sticks, beds, wheelchairs, beddings, trolleys, toilets, and the like.

  The invention described in this specification is listed below as an example.

  (Claim 1) Branches and leaves of the genus Euphoridae, rhizomes of the plant of the genus Ganaceae, all plants of the genus Isodon plant, the rhizomes of the plant of the family Lamiaceae, all the plants of the plant of the genus Salamander An antimicrobial coating film comprising an aqueous extract of at least one plant selected from the group consisting of bark of urchinaceae Ranshinboku and its branches and leaves and all plants of Asteraceae.

  (Claim 2) All plant bodies of Lamiaceae Isodon genus plants, rhizomes of Lamiaceae genus Capillaris, all plants of Ganoderma genus plants, bark and branches and leaves of Urushiaceae ransymbol genus An antimicrobial coating film containing an organic solvent extract of at least one plant selected from the group consisting of plant rhizomes.

  (Claim 3) The antimicrobial coating film according to claim 1 or 2, further comprising a coating resin.

  (Claim 4) The antimicrobial coating film according to claim 3, wherein the paint resin contains a resin in an aqueous paint which is emulsified and dispersed in water.

  (Claim 5) The content of the water extract or the organic solvent extract is 1 part by weight or more and 500 parts by weight or less with respect to 100 parts by weight of the solid content of the coating resin. Antimicrobial coating.

  (Claim 6) The antimicrobial coating film according to any one of claims 1 to 5, further comprising an inorganic carrier.

  (7) The antimicrobial coating film according to (6), wherein the inorganic carrier is a particulate powder composed of an intercalation compound.

(8) The inorganic carrier is a particulate powder mainly composed of a porous inorganic oxide, having a specific surface area of 300 m ² / g or more and having a silanol group on the surface and a particle size of 50 μm or less. Item 8. The antimicrobial coating film according to Item 6 or 7.

  (Claim 9) The antimicrobial coating film according to any one of claims 1 to 8, further comprising a catechin and / or a silver antibacterial agent.

  (Claim 10) The antimicrobial coating film according to claim 9, wherein the silver antibacterial agent includes a carrier on which a silver complex and / or silver ions are supported.

  (Claim 11) A filter in which a plurality of fibers intersect, wherein the antimicrobial coating film according to any one of claims 1 to 10 is formed at an intersection of the fibers.

  (Claim 12) An air quality adjusting electrical device equipped with the filter according to claim 11.

  (Claim 13) The air quality adjusting electrical device according to claim 12, which is any one of an air cleaner, an air conditioner, a humidifier, and a vacuum cleaner.

  (Claim 14) An industrial product in which the antimicrobial coating film according to any one of claims 1 to 10 is formed on a casing or a component base material.

  (Claim 15) Building materials, stationery, clothing, accessories, home gardening materials, office equipment, interior members, exterior members, vending machines, automobile parts, electrical product parts, traffic-related equipment, furniture, household goods, cooking equipment, The industrial product according to claim 14, which is either a medical product or a care medical welfare facility.

  The antimicrobial coating film of the present invention exhibits strong antimicrobial performance against harmful microorganisms existing in the living environment, in other words, microorganisms to be removed when creating an amenity environment. Moreover, the plant body extract used by this invention has confirmed the safety | security from the track record used from ancient times as a raw material of Chinese medicine. Since the materials (such as fixtures and building materials) in the living environment on which the antimicrobial coating film of the present invention is formed have high safety, they can be used with confidence. Unlike the synthetic antibacterial agent that is used only in an emergency, this utilization effect is an effect that is necessary for the permanent presence in the living environment.

  Therefore, for the antimicrobial treatment of materials in the living environment, the antimicrobial coating film of the present invention is formed on the material, ensuring safety, keeping the living environment clean and building materials, etc. It is possible to prevent deterioration of living-related materials due to microorganisms. Furthermore, by inhibiting the growth of harmful microorganisms, it is possible to prevent the development of allergies associated with the floating and scattering of microorganisms. Thus, the industrial effect by this invention is large.

  Hereinafter, embodiments of the present invention will be described. In the following embodiments, a water extract of the leaves of the genus Eucalyptus plant, a water extract of the rhizome plant, a rhizome plant, a water extract of the allergic plant of the Labiatae plant, a water extract of the rhododendron plant Rhizome plant rhizome, Aqueous extract of the whole plant of Salagoaceae, Aqueous extract of bark of Ranunculaceae plant, Aqueous extract of branch leaf of Ranunculaceae plant, Aqueous extract of all plant of Chrysanthemum family, Mansihyo Kokoshi plant Organic solvent extract of whole plant on the ground, Organic solvent extract of rhizobia Rhizome Rhizome rhizome, Organic solvent extract of Rhizophoraceae Nagasaruogase plant whole plant, Organic solvent extract of Urushiaceae Lanshinboku bark, Urchinaceae Lanshinboku plant Among organic solvent extracts of branches and leaves and organic solvent extracts of rhizomes Even without using a kind of plant extracts.

(Embodiment 1)
The following describes the antibacterial performance of the water extract of the Chinese branch of Eucalyptus plant and the method for producing the antimicrobial coating containing this extract. The branches and leaves of the Euphorbiaceae plant used for extraction are those that have been picked and dried in the shade. A hot water-soluble substance was obtained by water extraction, specifically, steam distillation, of the genus Eucalyptus plant. This was concentrated by a rotary evaporator to obtain a brownish brown-like substance.

  Commonly used extraction methods include, for example, a method in which a raw plant part is immersed in an organic solvent for a long time, a method in which heating is performed at a temperature below the boiling point of the organic solvent, extraction is performed with stirring, and an extract is obtained by filtration and so on. However, by performing extraction with water, a product having a high antibacterial performance and a wide antibacterial spectrum can be obtained.

  Regarding the evaluation of antibacterial performance, there are an antibacterial performance evaluation for the extract itself and an evaluation for an antimicrobial coating film obtained by processing the extract so that it can be applied to actual use. First, after antibacterial performance evaluation for the extract itself, the antimicrobial coating is evaluated.

  In order to compare the water extract of the present embodiment with the polar organic solvent extract disclosed in JP-A-11-80012, the antibacterial performance evaluation results are shown in Table 1. In addition, acetone of ketones was used as a polar organic solvent.

As test species, Escherichia coli as a gram-negative representative bacterium and Staphylococcus aureus as a gram-positive representative bacterium were used. The minimum growth inhibitory concentration (MIC) generally used as an index of antibacterial performance was used, and the test method was in accordance with the standard method (Japan Chemotherapy Society method, Antibacterial Product Technology Council method). Antibacterial performance is assessed at the minimum inhibitory concentration (MIC) for the strain. Therefore, it shows that antimicrobial performance is so strong that the value of MIC is small. In addition, when the value of MIC (ppm) was 1600 or less, it was decided to have antibacterial performance.

  As shown in Table 1, the Eucalyptus water extract of this embodiment showed antibacterial performance against gram-negative bacteria including E. coli and gram-positive bacteria including S. aureus. On the other hand, the Eucalyptus organic solvent extract showed antibacterial performance only against Staphylococcus aureus and did not show good or practical antibacterial performance against Escherichia coli.

  From the results in Table 1, it was found that the antibacterial spectrum of the extract differs depending on the extraction method. Specifically, the organic solvent extract disclosed in Japanese Patent Application Laid-Open No. 11-80012 was unable to find an effect in numerical evaluation such as MIC against gram-negative bacteria such as Escherichia coli. However, the water extract has a broad antibacterial spectrum and has been found to have an antibacterial effect against gram-negative bacteria.

  Next, the manufacturing method of the antimicrobial coating film containing the water extract of this embodiment is demonstrated. First, 10 parts by weight (in terms of solid weight) of an aqueous acrylic resin emulsion (manufactured by Toyo Ink Manufacturing Co., Ltd., trade name: PAW aqueous screen ink) was prepared as a paint binder (paint resin). To this, 1 part by weight of a water extract was mixed and sufficiently dispersed to prepare an antimicrobial paint.

  As shown below, an antimicrobial coating film was formed using the obtained antimicrobial paint, and its antibacterial performance was evaluated.

  1. A paint resin and a water extract are kneaded and spread on a PET (polyethylene terephthalate) film. The coating amount is about 0.1 g / sheet (before drying). As the PET film, a 125 μm thick PET film (trade name: Lumirror (U943) manufactured by Toray Industries, Inc.) was used.

  2. After painting, let it air dry at room temperature. Thereafter, forced drying is performed at 60 ° C. for 1 hour using a dryer, and the test is performed.

  3. A bacterial solution (0.4 ml) is dropped on the coating film, and the top is covered with a film. After standing at 37 ° C. for 24 hours, the bacterial solution is collected and cultured to determine the number of viable bacteria. The culture time was 48 hours for S. aureus and 24 hours for E. coli.

  Except not using a water extract, the test piece was created similarly to this embodiment, and this was used for evaluation as a blank. Moreover, the test piece was created similarly to this embodiment using the organic solvent extract. Table 2 shows the evaluation test results of the antibacterial performance by the antimicrobial coating film of the present embodiment. Table 3 shows the evaluation test results of the antibacterial performance when using the organic solvent extract.

  In Tables 2 and 3, E and the subsequent numbers represent power numbers. In Tables 2 and 3, those having an MIC value (ppm) of 3200 or more were omitted from the table because their antibacterial properties were poor.

  As a result, high antibacterial performance was observed in the antimicrobial coating film containing the extract having a low MIC value. Specifically, the antimicrobial coating film containing the Eucalyptus water extract showed high antibacterial performance against gram-negative bacteria including Escherichia coli (see Table 2). On the other hand, for the Eucalyptus organic solvent extract, its antimicrobial coating also did not show good antibacterial performance against gram-negative bacteria (see Table 3).

  The antimicrobial coating of both the Eucalyptus water extract and the organic solvent extract showed high antibacterial performance against Gram-positive bacteria including S. aureus (see Tables 2 and 3). From the above results, it was confirmed that the antimicrobial coating film of the present embodiment using the Eucalyptus water extract exhibits high antibacterial performance against gram-negative bacteria and gram-positive bacteria.

  In the above, an aqueous acrylic resin emulsion was used to form a water extract into a coating film, but the results showed that the same antibacterial performance was exhibited even when another resin was used as the coating resin. Specifically, even when an emulsion containing other polymers such as a polyester resin, an epoxy resin, a urethane resin, a silicone resin, and a fluororesin was used, a result that the same antibacterial performance as that of the aqueous acrylic resin emulsion was exhibited was obtained. . Further, it was confirmed that even when a water-soluble resin such as polyvinyl alcohol or carboxymethyl cellulose is used as a highly hydrophilic resin or binder, practical antibacterial performance as an antimicrobial coating film can be exhibited.

  In particular, since the plant body extract is prepared by water extraction, the plant body extract has high water affinity and good affinity with water-based paints. Therefore, the antimicrobial coating film of the present embodiment can be formed without using an organic solvent using a water extract that can be easily developed in a water-based paint, which is advantageous in terms of painting work and environmental pollution. Industrial value is also great from the point of consideration of Furthermore, since microorganisms coexist with water and scatter with evaporation of water, the antibacterial component in the water extract has good affinity with the water around the microorganisms. Therefore, the antimicrobial coating film of the present embodiment has an actual use advantage that the antibacterial component easily affects the microorganism even in terms of the effect on the microorganism.

(Embodiment 2)
The following is a brief description of the antibacterial performance of the water extract of Chinese ginger family turmeric plant rhizome, the method of producing the antimicrobial coating containing this extract, and the antibacterial performance of each coating. The rhizome of the ginger family turmeric plant used for extraction is one that has been picked and dried in the shade. A hot water-soluble substance was obtained by water extraction of the ginger family turmeric rhizome, specifically steam distillation. By concentrating this with a rotary evaporator, a light brown liquid substance was obtained.

  In order to compare the water extract of this embodiment with the organic solvent (acetone) extract, the evaluation results of each antibacterial performance are shown in Table 1. Note that the test bacteria species, antibacterial performance evaluation method, and index (MIC) are the same as those in the first embodiment. As for the antibacterial performance, when the MIC value is 1600 or less, the antibacterial performance is assumed.

  As a result, the turmeric water extract of the present embodiment is slightly weaker than the Eucalyptus water extract of Embodiment 1 against Gram-negative bacteria such as E. coli and Gram-positive bacteria such as Staphylococcus aureus. Showed antibacterial performance. However, the turmeric organic solvent extract showed no antibacterial performance against any of the gram-negative and gram-positive bacteria.

  Next, the antimicrobial coating film containing a water extract was created with the manufacturing method similar to Embodiment 1. FIG. About the obtained antimicrobial coating film, it carried out similarly to Embodiment 1, and evaluated antibacterial performance. Table 2 shows the evaluation test results of the antibacterial performance by the antimicrobial coating film of the present embodiment. Table 3 shows the evaluation test results of the antibacterial performance of the antimicrobial coating film containing the organic solvent extract.

  As a result, antibacterial performance was observed in the antimicrobial coating film containing the extract having a low MIC value. Specifically, the antimicrobial coating film containing the banturmeric water extract showed antibacterial performance against gram-negative bacteria such as Escherichia coli. Moreover, the antimicrobial coating film containing a banturmeric water extract showed antibacterial performance also against Gram-positive bacteria including Staphylococcus aureus.

  However, the antimicrobial coating film containing the banturmeric organic solvent extract did not exhibit antibacterial performance against any of the gram-negative and gram-positive bacteria (not shown in the table).

  From the above results, it was confirmed that the antimicrobial coating film of the present embodiment containing an aqueous extract of Ginger family turmeric plant rhizome exhibits antibacterial performance against gram-negative bacteria and gram-positive bacteria.

(Embodiment 3)
Water extract of whole plant body of Lamiaceae manshhiokikoshi plant, water extract of rhododendron plant Rhizome plant rhizome, water extract of whole plant of Salagoaceae Nagasaoogase plant, water extract of bark and branch leaves of Ursiaceae The antibacterial performance of each of the water extracts of the antaceae plant, the production method of the antimicrobial coating film containing each water extract, and the antibacterial performance of each coating film are briefly described below.

  All plant bodies of Lamiaceae manshhiokikoshi plants above ground, Lamiaceae kogane willow plant rhizomes, Alloaceae Nagasaroogase plant whole plant, Urushiaceae ranshinboku bark and branch leaves, Asteraceae daisies All plant plants were shaded after picking Each was subjected to extraction.

  A water-soluble substance was obtained by water extraction of each plant or a part thereof, specifically, steam distillation. Further, the components were concentrated by a rotary evaporator. Each water extract has the following characteristics. All of the above-mentioned plant bodies of the Lamiaceae manshhiokikoshi plant are brownish-brown, the rhododendron islets are brownish-brown, the all-spotted plant is a light brown powder, and the bark and branches of the urchinaceae are brown-brown. The whole plant of Asteraceae is a black grease.

  In order to compare the water extract of each plant with the organic solvent (acetone) extract, the evaluation results of each antibacterial performance are shown in Table 1. Note that the test bacteria species, antibacterial performance evaluation method, and index (MIC) are the same as those in the first embodiment. As for the antibacterial performance, when the MIC value is 1600 or less, the antibacterial performance is assumed.

  As a result, the water extract showed antibacterial performance against Gram-positive bacteria such as Staphylococcus aureus. On the other hand, in the organic solvent extract, Manshuhiki Kokoshi, Shirogane willow, Nagasaruogase, and Lanshinboku showed antibacterial performance against Gram-positive bacteria including Staphylococcus aureus.

  Next, the antimicrobial coating film containing each water extract was created with the manufacturing method similar to Embodiment 1, respectively. About the obtained antimicrobial coating film, it carried out similarly to Embodiment 1, and evaluated antibacterial performance. Table 2 shows the evaluation test results of the antibacterial performance by the antimicrobial coating film of the present embodiment. Table 3 shows the evaluation test results of the antibacterial performance of the antimicrobial coating film containing the organic solvent extract.

  As a result, antibacterial performance was observed in the antimicrobial coating film containing the extract having a low MIC value. Specifically, antibacterial coatings that contain water extracts of Manshuhiki Koshi, Koganagi willow, Nagasaruogase, Lanshinboku, and Taikinku show high antibacterial performance against Gram-positive bacteria such as Staphylococcus aureus. It was.

  From the above results, it was confirmed that the antimicrobial coating film of the present embodiment containing each water extract of Manshuhiki Kokoshi, Shirokane willow, Nagasaruogase, Lansingbok, Taikinku shows high antibacterial performance against Gram-positive bacteria. It was. In this embodiment, the water extract of the bark and branches and leaves of the urchinaceae ranshinboku plant was used, but even when either the water extract of the bark of the urchinaceae ransymbol plant or the water extract of the branches and leaves was used, both Antibacterial performance equivalent to the water extract of

(Embodiment 4)
Organic solvent extract of whole plant body of Lamiaceae manshhiokokushi plant, organic solvent extract of rhizome plant Rhizome plant rhizome, organic solvent extract of all plant of Salagoaceae Nagasaroogase plant, Urushi family Lanshinboku plant bark and leaves The following is a brief description of the antibacterial performance of each organic solvent extract and Rhizome rhizome organic solvent extract, the preparation of antimicrobial coatings containing each organic solvent extract, and the antibacterial performance of each coating. .

  All plant bodies of Lamiaceae Manshuhikiokoshi plant above ground, Lamiaceae kogane willow plant rhizome, Salogaceae Nagasaruogase plant whole plant, Ursiaceae ransymbol plant bark and branches and leaves, Rhizoaceae Rhizome rhizome are those that have been shaded after picking It used for extraction.

  Each plant body (whole plant body or a part thereof) is extracted with an organic solvent, specifically, a mixed organic solvent of 70% acetone and 30% water, and a substance soluble in the organic solvent is obtained by distillation using a rotary evaporator. Obtained. Further, the components were concentrated by a rotary evaporator. Each organic solvent extract has the following characteristics. All the plant bodies of the Lamiaceae Manshuhikiokoshi plant are dark-powder-colored powder, the Lamiaceae white-rooted plant rhizome is yellow-powdered, and the all-spotted plant is the ivory-colored needle-shaped crystal powder. The branches and leaves are in the form of a light orange powder, and the rhizome of the rhododendron is a dark brown high viscosity.

  In order to compare the organic solvent extract and the water extract of each plant, the evaluation results of the antibacterial performance are shown in Table 1. The test bacteria species, the antibacterial performance evaluation method and the index (MIC) are the same as in the first embodiment. As for the antibacterial performance, the antibacterial performance was obtained when the MIC value was 1600 or less.

  As a result, as for the water extract, Manshuhiki Kokoshi, Shirogane willow, Nagasaruogase, and Lanshinboku showed antibacterial performance against Gram-positive bacteria including Staphylococcus aureus. On the other hand, in the organic solvent extract, Manshuhiki Kokoshi, Shirogane willow, Nagasaruogase, Lanshinboku, and Diou showed antibacterial performance against Gram-positive bacteria including Staphylococcus aureus.

  Next, the manufacturing method of the antimicrobial coating film containing the organic solvent extract of each plant body is demonstrated. First, as a paint binder (paint resin), a mixed liquid of 10 parts by weight of water-based urethane resin (converted to solid weight) and 1 part by weight of acrylic latex (converted to solid weight) was prepared. To this, 1 part by weight of an organic solvent extract was mixed and sufficiently dispersed to prepare an antimicrobial paint. The water-based urethane resin used here is RA85 (trade name) manufactured by Nippon SC Co., Ltd., and the acrylic latex is LX854C (trade name) manufactured by Nippon Zeon Co., Ltd.

  In the same manner as in Embodiment 1, antimicrobial coating films containing each organic solvent extract were prepared. About the obtained antimicrobial coating film, it carried out similarly to Embodiment 1, and evaluated antibacterial performance. Table 3 shows the evaluation test results of the antibacterial performance by the antimicrobial coating film of this embodiment.

  As a result, high antibacterial performance was observed in the antimicrobial coating film containing the extract having a low MIC value. Specifically, antibacterial coatings that contain organic solvent extracts of Satsuma staphylococci and other Gram-positive bacteria, such as Manshuhiki Koshi, Kogane willow, Nagasaru Ogase, Lanshinboku, and Daio, exhibit high antibacterial performance. It was. On the other hand, none of the gram-negative bacteria including Escherichia coli showed high antibacterial performance.

  From the above results, it was confirmed that the antimicrobial coating film of the present embodiment containing each of the organic solvent extracts of Manshuhiki Kokoshi, Kogane willow, Nagasaru Ogase, Lansingbok, and Daio exhibits high antibacterial performance against Gram-positive bacteria. It was done. In the present embodiment, the organic solvent extract of bark and branch leaves of Ursiaceae Lanshinboku plant was used, but when either one of the organic solvent extract of bark of Ursiaceae Lansinboku plant or the organic solvent extract of branches and leaves was used. However, it showed antibacterial performance equivalent to both organic solvent extracts.

(Embodiment 5)
In this embodiment, the influence which the extract density | concentration in a coating film has on antibacterial performance and a coating-film characteristic is evaluated. As an extract to be used for the test, an organic solvent extract of Nagasaruogase prepared in Embodiment 4 was used. The resin used is a urethane resin, which is a water-soluble urethane resin using water as a solvent. In terms of solid content, 0.1 to 500 parts by weight of the present extract was mixed and dispersed with respect to 100 parts by weight of the water-soluble urethane resin, and the antibacterial performance was evaluated. The evaluation test method is the same method as the antibacterial performance evaluation described in the first embodiment. Specifically, the sample used for the evaluation test was prepared by the following method.

  (1) An antimicrobial paint was prepared by mixing 1 part by weight of the present extract, 100 parts by weight of the above resin in terms of solid weight, and a coating solvent (water). It was diluted with a coating solvent (water) to a viscosity that is easy to paint.

(2) The paint prepared in the above (1) was applied to the surface of a PET film having a 5 cm square and a thickness of 125 μm by a roll coater method at an application amount (in terms of dry weight) of about 100 mg / 25 cm ² . After painting, it was dried with sufficient ventilation in a place where it was not dusty until it was sufficiently dry. Then, after forcedly drying with a dryer at 60 ° C. for about 1 hour, it was subjected to antibacterial performance evaluation.

  In addition, a “blank” sample not containing the present extract and containing other resin components was prepared in the same manner. The net weight of the extract was calculated by measuring the weight of each sample before and after coating. Similarly, samples with various changes in the mixing ratio of the present extract and the coating resin were prepared, and the antibacterial performance of each sample was evaluated. The results are shown in Table 4. When the number of surviving bacteria is compared between the sample and the blank, the ratio of surviving bacteria 24 hours after the start of the test (blank / sample) is 1000 or more, “◎”, when less than 1000 is 100 or more, “◯”, When less than 100 and 50 or more, “Δ” is given in Table 4, respectively.

  From the above results, by applying antimicrobial paint at a coating weight ratio of 0.1 or more in the dry weight ratio in the coating film, it exhibits antibacterial performance more than a practical level against microorganisms present in the living environment. I understand. In particular, an antimicrobial coating formed by using an antimicrobial paint obtained by mixing 1 part by weight to 500 parts by weight of this extract with 100 parts by weight of a water-soluble urethane resin has practical antibacterial performance. It was confirmed. Moreover, when 100 parts by weight or less of the present extract was mixed with 100 parts by weight of the water-soluble urethane resin, it was confirmed that practical coating characteristics were obtained. It is considered that the safety of the antimicrobial coating film is high due to the fact that the raw material of this extract has been used for many years as a raw material for traditional Chinese medicines.

  The same tendency as in the case of using the water-soluble urethane resin was shown when the paint resin was changed to polyvinyl alcohol, carboxymethyl cellulose, epoxy resin, or polyester resin instead of the water-soluble urethane resin. In addition, the same experiment was performed on other extracts, and similar results were obtained.

(Embodiment 6)
This embodiment demonstrates the antimicrobial coating film by which the active ingredient of the plant body was carry | supported by the inorganic support | carrier. As the plant body, the whole plant body of Lamiaceae Manshuhikiokoshi was used. All the plant bodies above the ground part of Lamiaceae Manshuhikiokoshi were cut from summer to autumn, removed foreign substances, dried sufficiently, and then subjected to extraction.

  The whole plant body of Manshuhiki Kokoshi was dipped in a mixed organic solvent of 70% acetone and 30% water to extract substances soluble in the mixed solvent. Concentrated components were concentrated using a spray drying method to obtain a dark earth powder soluble in a water / ethanol solvent.

As an inorganic carrier, a hydrotalcite compound compound (plate surface diameter 0.3 μm, thickness 0.06 μm, specific surface area 14 m ² / g) powder (manufactured by Toda Kogyo Co., Ltd.) was prepared. 1 part by weight of this powder and 1 part by weight of this extract were dispersed in a mixed solvent of 70% ethyl alcohol and 30% water. After sufficiently dispersing, the solvent is evaporated while stirring to obtain antimicrobial particles in which the present extract is supported on an inorganic carrier.

  The antimicrobial paint was prepared by dispersing the antimicrobial particles in an aqueous paint in which polyvinyl alcohol as a paint resin was dissolved in water as a coating solvent. Specifically, the antibacterial properties include 5 parts by weight of the present extract, 5 parts by weight of a hydrotalcite compound as an inorganic carrier, and 90 parts by weight of polyvinyl alcohol in terms of film weight after coating. A paint was prepared. The antimicrobial performance of this antimicrobial paint was similarly evaluated using the evaluation method described in Embodiment 1. As a result, it was confirmed that the antimicrobial coating film in which the antimicrobial particles carrying the extract were dispersed had practical coating performance and antibacterial performance against gram-positive bacteria.

  In this embodiment, since this extract is carry | supported by the inorganic support | carrier, the heat resistance of this extract can be improved. In addition, since the present extract is present not only in the outer surface of the inorganic carrier but also in the pores of the inorganic carrier, the present extract in the pores is not lost even if the outer surface extract is lost due to rain water or the like. It can remain and maintain its antimicrobial action.

  The same tendency as in the case of using polyvinyl alcohol was shown when the paint resin was changed to water-soluble urethane resin, carboxymethyl cellulose, epoxy resin, or polyester resin instead of polyvinyl alcohol. In addition, the same experiment was performed on other extracts, and similar results were obtained.

(Embodiment 7)
Embodiment 6 Except that a particulate powder mainly composed of a porous inorganic oxide, having a specific surface area of 300 m ² / g or more and having a silanol group on the surface and having a particle size of 50 μm or less was used as the inorganic carrier. In the same manner, an antimicrobial coating film was prepared. Specifically, antimicrobial particles are obtained through the same steps as in Embodiment 6 using silica gel fine particles (trade name: Silo Hovic 200, manufactured by Fuji Silysia Chemical Co., Ltd.) having a particle size of 1 μm whose surface has been subjected to hydrophobic treatment. Was prepared.

  An antimicrobial paint was prepared using the antimicrobial particles. Specifically, an antimicrobial paint was prepared by mixing 5 parts by weight of a water extract of lanshinboku bark and / or branches and leaves, 2 parts by weight of silica gel powder, and 93 parts by weight of a water-soluble urethane resin (in terms of solid weight).

  As a result, as in the case of using a hydrotalcite compound as an inorganic carrier, the antimicrobial coating film containing silica gel particles carrying the extract has practical coating performance and antibacterial performance. Was confirmed.

  The same tendency as in the case of using the water-soluble urethane resin was shown when the paint resin was changed to polyvinyl alcohol, carboxymethyl cellulose, epoxy resin, or polyester resin instead of the water-soluble urethane resin. In addition, the same experiment was performed on other extracts, and similar results were obtained.

(Embodiment 8)
In the present embodiment, an antimicrobial coating film containing catechins attracting attention in recent years and at least one plant extract will be described. The antimicrobial coating film of the present embodiment contains an aqueous extract of branches of Euphorbiaceae, catechins, and a coating solvent.

  Catechin is a water-soluble component contained in tea leaves and is generally called tannin because of its astringency. Tea catechins include epigallocatechin gallate, epicatechin, epicatechin gallate, epigallocatechin, catechin and the like.

  The catechins used in this embodiment are tea leaf extracts, and the MIC against Gram-positive bacteria is reported to be 250-800 ppm against S. aureus (Antibacterial Chemistry II, published by Industrial Research Council). . However, the antibacterial performance of catechins against gram-negative bacteria has not been reported.

  According to the production method described in the first embodiment, an aqueous extract of branches and leaves of the Eucalyptus plant from China is prepared. This extract and catechins were mixed at a weight ratio of 1: 1, and these were dispersed in a coating solvent (water) at a concentration sufficient to achieve coating performance to prepare an antimicrobial paint.

  Using this antimicrobial paint, an antimicrobial coating film was prepared in the same manner as in Embodiment 5, and antibacterial performance was evaluated. As a result, it was confirmed that practical antibacterial performance and coating film characteristics can be obtained.

(Embodiment 9)
In the present embodiment, an antimicrobial coating film containing a silver antibacterial agent will be described. The antimicrobial coating film of the present embodiment contains a water extract of rhizobiae Rhizobium plant rhizome, a silver complex antibacterial agent, a coating resin, and a coating solvent.

  The rhizome plant Rhizome rhizome was sufficiently dried and then subjected to extraction. A hot water-soluble substance was obtained by immersing rhizome Rhizome willow plant rhizomes in water. This material was pulverized using a spray drying method to give a yellow powder.

  1 part by weight of silver complex antibacterial agent (trade name: Amenitop, manufactured by Matsushita Electric Industrial Co., Ltd.) coated with adsorption of thiosulfato silver complex on silica gel and coated with tetraethoxysilane hydrolyzate, After 1 part by weight of a rhizome water extract was dispersed in 20 parts by weight of water as a solvent, the water was evaporated and dried with stirring. Thereby, the antimicrobial particle | grains which this extract adhered to the silver complex antimicrobial agent surface were prepared. A coating binder was prepared by dispersing 98 parts by weight of carboxymethylcellulose in a coating solvent (water) to such an extent that the coating performance was exhibited. An antimicrobial paint was prepared by dispersing 2 parts by weight of the antibacterial particles in this paint binder.

  Using this antimicrobial paint, an antimicrobial coating film was prepared in the same manner as in Embodiment 5, and antibacterial performance was evaluated. As a result, it was confirmed that practical antibacterial performance and coating film characteristics can be obtained.

  In the case where the coating resin was changed to polyvinyl alcohol, water-soluble urethane resin, epoxy resin, or polyester resin instead of carboxymethyl cellulose, the same tendency as in the case of using the water-soluble urethane resin was shown. In addition, the same experiment was performed on other extracts, and similar results were obtained.

(Embodiment 10)
In the present embodiment, an air filter having an antimicrobial coating will be described. A water extract of Chinese leaves of Eucalyptus plant prepared by the same production method as in Embodiment 1 and an aqueous extract of the whole plant body of the Sarcophaceae Nagasaroogase plant prepared by the same production method as in Embodiment 4 were prepared. . An antimicrobial paint was prepared by mixing and dispersing 2 parts by weight of the extraction mixture obtained by mixing the two in a ratio of 98 parts by weight of an aqueous acrylic resin in terms of solid weight.

  On the other hand, the nonwoven fabric used for the filter for air cleaners was prepared. This filter has a pre-filter layer and a charged filter layer. The prefilter layer is a polypropylene non-woven fabric made of fibers having a diameter of about 30 μm, and a charged filter layer is formed of polypropylene ultrafine fibers melt-blown thereon. The antimicrobial paint was printed only on the surface of the prefilter layer opposite to the charged filter layer by the gravure printing method. An antimicrobial coating film was formed by drying the printed antimicrobial paint.

  FIG. 1 is a partially enlarged view of the prefilter layer. As shown in FIG. 1, the nonwoven fabric has a plurality of polypropylene fibers (1) intersecting each other, and an antimicrobial coating (2) in which the extraction mixture (3) is dispersed is at the intersection of the fibers (1). Is formed. Actually, the extraction mixture (3) is dissolved and dispersed in the antimicrobial coating (2), and the extraction mixture (3) does not become particulate, but FIG. 1 schematically shows the dispersion. Therefore, the extraction mixture (3) is displayed as particles.

  By printing the antimicrobial paint by the gravure printing method, it becomes possible to attach and apply the antimicrobial paint to at least the fiber intersection of the nonwoven fabric. In other words, since the antimicrobial paint is applied in the vicinity of the fiber intersection on the surface of the prefilter layer, the antimicrobial paint does not enter the inside of the filter layer, and pressure loss of air passing through the filter hardly occurs. In addition, the antimicrobial coating (2) exhibits antibacterial performance against microorganisms collected and attached to the filter surface (especially near the fiber intersection) from the airflow.

  Table 5 shows the results of measuring the antibacterial performance of the filter surface. Microorganisms activated in the logarithmic growth phase were dropped on the filter as the initial number of bacteria, and the number of living bacteria after being left in an atmosphere at 35 ° C. for 24 hours was counted. In addition, antibacterial performance was measured in the same manner for a conventional unprocessed filter that was not processed with an antimicrobial paint, and the result is shown in Table 5 as “Conventional filter”. The numbers in Table 5 are the number of viable bacteria on the filter surface (unit: cfu / ml).

  As shown in Table 5, practical antibacterial performance was recognized for the filter of this embodiment. The air cleaner equipped with this filter also showed practical antibacterial performance.

  In the present embodiment, the filter for an air purifier has been described. However, a filter on which an antimicrobial coating film is formed may be applied to a water purifier.

(Embodiment 11)
In this embodiment, a medical record file will be described as an example of an industrial product having an antimicrobial coating. A water extract of branches and leaves of a Chinese genus Eucalyptus plant prepared by the same production method as in Embodiment 1 and a water extract of a Ginger family turmeric plant rhizome prepared by the same production method as in Embodiment 2 were prepared. An antimicrobial paint was prepared by mixing and dispersing 3 parts by weight of the extraction mixture obtained by mixing the two in a ratio of 97 parts by weight with an aqueous acrylic resin in terms of solid weight.

On the other hand, a base paper (150 g / m ² ) serving as a base material is prepared, and the base paper is impregnated with a synthetic rubber latex resin. By calendering, a soft vinyl chloride resin film having a film thickness of about 80 μm is formed on the surface of the base paper, and the surface texture and color tone are adjusted. On the surface-treated base paper, the antimicrobial paint is applied in a film thickness of about 2 to 6 μm by gravure coating. This was cut, punched and bent to create a chart file.

  The antibacterial performance on the surface of the medical record file was evaluated by the same test method as in the first embodiment. The results are shown in Table 6. In addition, antibacterial performance was measured in the same manner for a chart file whose surface was not subjected to antibacterial processing, and the result is shown in Table 6 as “untreated product”. The numbers in Table 6 are the number of viable bacteria on the surface of the chart file (unit: cfu / ml).

  As shown in Table 6, practical antibacterial performance was recognized in the medical record file of this embodiment. In addition, an antimicrobial coating film is formed by coating an antimicrobial paint containing at least one plant extract defined in the present invention on a housing or a component base material, or impregnating the base material. An industrial product with The produced industrial products are wallpaper, stationery, automobile parts, furniture, cooking utensils, and medical utensils. As a result of evaluating the surface antibacterial performance of these industrial products, all of them showed practically good antibacterial performance.

  As mentioned above, although embodiment of this invention was described, the technical scope of this invention is not limited to the range as described in the said embodiment. The above embodiment is an exemplification, and it is understood by those skilled in the art that various modifications can be made to each of those components, and that such modifications are also within the technical scope of the present invention.

  The antimicrobial coating film of the present invention can be used to prevent various harmful effects caused by microorganisms. For example, antibacterial surface treatment for life-related materials, antiseptic treatment for industrial products and their components, treatment for preventing corrosion of building-related materials by microorganisms, antiseptic treatment for food-related materials, microbial control for distribution packaging materials, and odor control It is useful for applications such as microorganism control in water treatment. It can also be applied as a microbial control agent for medicine-related materials, a disinfectant for public health, and the like.

It is the elements on larger scale of a pre filter layer.

Explanation of symbols

1 Polypropylene fiber 2 Antimicrobial coating 3 Extraction mixture

Claims (10)

  Panaceae Eucalyptus plant branch and leaf, Ginger family turmeric rhizome, Lamiaceae manshhiokikoshi plant all-ground plant, Lamiaceae kogane willow plant rhizome, Salvoniaceae Nagasaruogase plant whole plant, Urushiaceae ranshinboku plant bark and / or branch leaf, Asteraceae An antimicrobial coating film characterized by comprising at least a plant water extract of a whole plant body and a paint resin.   Plant organic solvent extract of all the plant bodies of Lamiaceae Manshuhikiokoshi plant, Rhizoaceae Saccharum plant rhizome, Salogaceae Nagasaruogase plant, Urushi family Ranshinboku plant bark and / or branch leaf, Lariaceae Rhizome rhizome And an antimicrobial coating film comprising at least a coating resin.   The antimicrobial coating film according to claim 1 or 2, wherein the coating resin contains an aqueous coating resin in which the resin is emulsified and dispersed in water.   The amount of the plant body water extract or the plant body organic solvent extract is 1 part by weight to 500 parts by weight in the antimicrobial coating with respect to 100 parts by weight of the coating resin solid content. The antimicrobial coating film of any one of Claim 1 to 3.   The antimicrobial coating film according to any one of claims 1 to 4, wherein at least an inorganic carrier is dispersed in the coating film. 6. The inorganic carrier according to claim 5, wherein the inorganic carrier is an inorganic oxide compound, and has a specific surface area of at least 300 m ² / g or more and a particulate powder having a particle size of 50 μm or less having a silanol group on the surface. Antimicrobial coating.   The antimicrobial coating film according to any one of claims 1 to 5, comprising catechin and / or a silver-based antibacterial agent.   The antimicrobial coating film according to claim 7, wherein the silver-based antibacterial agent has a structure in which a silver complex and / or silver ions are supported on a carrier as a main component.   An industrial product equipped with an air filter comprising the antimicrobial coating film according to any one of claims 1 to 8 at least at a fiber intersection of a nonwoven fabric. An industrial product comprising the antimicrobial coating film according to any one of claims 1 to 8 on at least a product housing and a component base material.

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