JP2005538935A - カルボキシフラーレンおよびその使用方法 - Google Patents

カルボキシフラーレンおよびその使用方法 Download PDF

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JP2005538935A
JP2005538935A JP2003571482A JP2003571482A JP2005538935A JP 2005538935 A JP2005538935 A JP 2005538935A JP 2003571482 A JP2003571482 A JP 2003571482A JP 2003571482 A JP2003571482 A JP 2003571482A JP 2005538935 A JP2005538935 A JP 2005538935A
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compound
cooh
carbon atoms
adjacent carbon
composition
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JP2005538935A5 (https=
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ドウーガン,ローラ・エル
ラベツト,エバ・ジー
クイツク,ケビン・エル
ハード,ジヨシユア・アイ
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ワシントン・ユニバーシテイ・スクール・オブ・メデイスン
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00Manufacture or treatment of nanostructures
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00Carbon; Compounds thereof
    • C01B32/15Nano-sized carbon materials
    • CCHEMISTRY; METALLURGY
    • C01INORGANIC CHEMISTRY
    • C01BNON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
    • C01B32/00Carbon; Compounds thereof
    • C01B32/15Nano-sized carbon materials
    • C01B32/152Fullerenes
    • C01B32/156After-treatment
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16Unsaturated compounds
    • C07C61/39Unsaturated compounds containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2604/00Fullerenes, e.g. C60 buckminsterfullerene or C70

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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nanotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Manufacturing & Machinery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Composite Materials (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003571482A 2002-02-23 2003-02-20 カルボキシフラーレンおよびその使用方法 Withdrawn JP2005538935A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/083,283 US20030162837A1 (en) 2002-02-23 2002-02-23 Carboxyfullerenes and methods of use thereof
PCT/US2003/005332 WO2003072802A2 (en) 2002-02-23 2003-02-20 Carboxyfullerenes and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2005538935A true JP2005538935A (ja) 2005-12-22
JP2005538935A5 JP2005538935A5 (https=) 2006-04-06

Family

ID=27753271

Family Applications (1)

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JP2003571482A Withdrawn JP2005538935A (ja) 2002-02-23 2003-02-20 カルボキシフラーレンおよびその使用方法

Country Status (6)

Country Link
US (1) US20030162837A1 (https=)
EP (1) EP1476150A4 (https=)
JP (1) JP2005538935A (https=)
AU (1) AU2003213206A1 (https=)
CA (1) CA2476782A1 (https=)
WO (1) WO2003072802A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013028584A (ja) * 2011-06-24 2013-02-07 Kagawa Univ 寿命延長剤

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7145032B2 (en) * 2002-02-23 2006-12-05 Washington University Therapeutic malonic acid/acetic acid C60 tri-adducts of buckminsterfullerene and methods related thereto
US20050058675A1 (en) * 2003-04-10 2005-03-17 Wilson Stephen R. Fullerene compositions for ameliorating dermatological conditions
US7163956B2 (en) * 2003-10-10 2007-01-16 C Sixty Inc. Substituted fullerene compositions and their use as antioxidants
US20050288236A1 (en) * 2003-10-10 2005-12-29 Russ Lebovitz Substituted fullerene formulations and their use in ameliorating oxidative stress diseases or inhibiting cell death
US20060247152A1 (en) * 2005-05-02 2006-11-02 Russ Lebovitz Substituted fullerenes and their use as inhibitors of cell death
WO2005058752A2 (en) * 2003-12-15 2005-06-30 Nano-C, Inc. Higher fullerenes useful as radical scavengers
WO2006028635A2 (en) * 2004-09-02 2006-03-16 C Sixty Inc. Fullerene compositions for ameliorating hearing loss, collateral damage of chemotherapy, or mucositis
JP2006160664A (ja) * 2004-12-07 2006-06-22 Vitamin C60 Bioresearch Kk フリーラジカル疾患予防治療用組成物
US20060188723A1 (en) * 2005-02-22 2006-08-24 Eastman Kodak Company Coating compositions containing single wall carbon nanotubes
US20070292622A1 (en) * 2005-08-04 2007-12-20 Rowley Lawrence A Solvent containing carbon nanotube aqueous dispersions
US20080020977A1 (en) * 2005-11-21 2008-01-24 Russ Lebovitz Use of Fullerenes to Oxidize Reduced Redox Proteins
US20090123893A1 (en) * 2007-06-08 2009-05-14 Alleman David S Method of performing and teaching adhesive dentistry
WO2009114089A2 (en) * 2008-03-03 2009-09-17 Luna Innovations Incorporated Using fullerenes to enhance and stimulate hair growth
JP2011513401A (ja) * 2008-03-03 2011-04-28 ルナ イノベーションズ インコーポレイテッド フラーレンを投与することにより動脈プラークの蓄積を抑制するための方法
US8598150B1 (en) 2008-04-02 2013-12-03 Jonathan R. Brestoff Composition and method for affecting obesity and related conditions
US8987245B2 (en) 2008-04-02 2015-03-24 Jonathan R. Brestoff Parker Composition and method for affecting obesity and related conditions
TN2011000327A1 (en) * 2011-06-30 2012-12-17 Fathi Moussa Fullerene and its use to maintain good health and to prolong the expected lifespan of mammals
US20200188339A1 (en) 2018-12-14 2020-06-18 Max Champie Nutraceutical Composition Comprising C60 And Ketone Esters
US11484508B2 (en) 2019-08-08 2022-11-01 Innovation for Success, LLC Dissolved C60 and method of producing dissolved C60
US10842742B1 (en) 2019-08-08 2020-11-24 Innovation for Success, LLC Dissolved C60 and method of producing dissolved C60
US11400113B2 (en) 2019-08-08 2022-08-02 Innovation for Success, LLC Dissolved C60 and method of producing dissolved C60
US12491209B2 (en) 2019-08-08 2025-12-09 Innovation for Success, LLC Dissolved C60 and method of producing dissolved C60
US12274713B2 (en) 2021-05-07 2025-04-15 Max C. Champie Nutraceutical composition comprising a water-soluble fullerene and a ketone

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01316328A (ja) * 1988-06-15 1989-12-21 Mitsui Toatsu Chem Inc 老化防止、細胞賦活、老人病予防・治療のための薬剤
US5648523A (en) * 1995-10-26 1997-07-15 Chiang Long Y Fullerene derivatives as free-radical scavengers
JP2000514412A (ja) * 1996-06-03 2000-10-31 エフ・ホフマン―ラ ロシュ アーゲー 神経毒性損傷の処置のためのバックミンスターフラーレンの使用
JP2001097888A (ja) * 1999-09-28 2001-04-10 Hiroshi Ikeno 外用組成物
US6265443B1 (en) * 1996-06-03 2001-07-24 Washington University Method for treating neuronal injury with carboxyfullerene
WO2001089542A2 (en) * 2000-05-25 2001-11-29 Pharmaton S.A. Composition for improving the cell protection comprising a lipophilic antioxidant and a hydrophilic antioxidant

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705781A (en) * 1986-10-08 1987-11-10 Giba-Geigy Corporation Method of treating cerebral ischemia using 4-(phosphono substituted lower alkyl or lower alkenyl)piperazine-2-carboxylic acids and salts, esters and amides thereof
DE4313481A1 (de) * 1993-04-24 1994-10-27 Hoechst Ag Fullerenderivate, Verfahren zur Herstellung und deren Verwendung
TWI250874B (en) * 2000-03-24 2006-03-11 Nat Health Research Institutes Pharmaceutical compositions for preventing or treating disorders associated with bacterial or viral infection
US6538153B1 (en) * 2001-09-25 2003-03-25 C Sixty Inc. Method of synthesis of water soluble fullerene polyacids using a macrocyclic malonate reactant
US7145032B2 (en) * 2002-02-23 2006-12-05 Washington University Therapeutic malonic acid/acetic acid C60 tri-adducts of buckminsterfullerene and methods related thereto

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01316328A (ja) * 1988-06-15 1989-12-21 Mitsui Toatsu Chem Inc 老化防止、細胞賦活、老人病予防・治療のための薬剤
US5648523A (en) * 1995-10-26 1997-07-15 Chiang Long Y Fullerene derivatives as free-radical scavengers
JP2000514412A (ja) * 1996-06-03 2000-10-31 エフ・ホフマン―ラ ロシュ アーゲー 神経毒性損傷の処置のためのバックミンスターフラーレンの使用
US6265443B1 (en) * 1996-06-03 2001-07-24 Washington University Method for treating neuronal injury with carboxyfullerene
JP2001097888A (ja) * 1999-09-28 2001-04-10 Hiroshi Ikeno 外用組成物
WO2001089542A2 (en) * 2000-05-25 2001-11-29 Pharmaton S.A. Composition for improving the cell protection comprising a lipophilic antioxidant and a hydrophilic antioxidant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013028584A (ja) * 2011-06-24 2013-02-07 Kagawa Univ 寿命延長剤

Also Published As

Publication number Publication date
EP1476150A4 (en) 2007-07-04
WO2003072802A3 (en) 2004-01-22
CA2476782A1 (en) 2003-09-04
US20030162837A1 (en) 2003-08-28
WO2003072802A2 (en) 2003-09-04
EP1476150A2 (en) 2004-11-17
AU2003213206A1 (en) 2003-09-09

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