JP2005538109A5 - - Google Patents
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- Publication number
- JP2005538109A5 JP2005538109A5 JP2004524924A JP2004524924A JP2005538109A5 JP 2005538109 A5 JP2005538109 A5 JP 2005538109A5 JP 2004524924 A JP2004524924 A JP 2004524924A JP 2004524924 A JP2004524924 A JP 2004524924A JP 2005538109 A5 JP2005538109 A5 JP 2005538109A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- compound
- pharmaceutical composition
- compound according
- agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*c(c(IC)c1)cc2c1OC(*)(*)[C@](C)C(*)C2*(C)C Chemical compound C*c(c(IC)c1)cc2c1OC(*)(*)[C@](C)C(*)C2*(C)C 0.000 description 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N c1ccccc1 Chemical compound c1ccccc1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39951802P | 2002-07-30 | 2002-07-30 | |
| PCT/US2003/023499 WO2004010992A1 (en) | 2002-07-30 | 2003-07-25 | Ppar alpha selective compounds for the treatment of dyslipidemia and other lipid disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005538109A JP2005538109A (ja) | 2005-12-15 |
| JP2005538109A5 true JP2005538109A5 (https=) | 2006-09-07 |
| JP4505327B2 JP4505327B2 (ja) | 2010-07-21 |
Family
ID=31188591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004524924A Expired - Fee Related JP4505327B2 (ja) | 2002-07-30 | 2003-07-25 | 異常脂血症および他の脂質障害の治療用のＰＰＡＲα選択的化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7297715B2 (https=) |
| EP (1) | EP1539137B1 (https=) |
| JP (1) | JP4505327B2 (https=) |
| AT (1) | ATE468851T1 (https=) |
| AU (1) | AU2003256911B2 (https=) |
| CA (1) | CA2493913A1 (https=) |
| DE (1) | DE60332738D1 (https=) |
| WO (1) | WO2004010992A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05007485A (es) | 2003-01-14 | 2006-01-30 | Arena Pharm Inc | Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia. |
| EA200501607A1 (ru) * | 2003-04-14 | 2006-06-30 | ДЗЕ ИНСТИТЬЮТС ФОР ФАРМАСЬЮТИКАЛ ДИСКАВЕРИ, ЭлЭлСи | Замещённые фенилалкановые кислоты |
| BRPI0409914A (pt) | 2003-04-30 | 2006-04-25 | Inst For Pharm Discovery Inc | ácidos carboxìlicos substituìdos |
| RS20060018A (sr) | 2003-07-14 | 2007-12-31 | Arena Pharmaceuticals Inc., | Derivati spojenih arila i heteroarila kao modulatori metabolizma u profilaksi i lečenju sa njima povezanih stanja |
| WO2005024057A1 (en) * | 2003-09-10 | 2005-03-17 | Galapagos Genomics N.V. | Method of identifying a compound that changes the amyloid-beta precursor protein processing in a cell |
| EP1566202A1 (en) * | 2004-02-23 | 2005-08-24 | Sahltech I Göteborg AB | Use of resistin antagonists in the treatment of rheumatoid arthritis |
| AU2005272389B2 (en) | 2004-08-11 | 2011-08-04 | Kyorin Pharmaceutical Co., Ltd. | Novel cyclic aminobenzoic acid derivative |
| MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| JPWO2006101108A1 (ja) * | 2005-03-23 | 2008-09-04 | 杏林製薬株式会社 | 新規環状アミノフェニルアルカン酸誘導体 |
| CA2676485A1 (en) * | 2007-01-23 | 2008-07-31 | Reddy Us Therapeutics, Inc. | Methods and compositions for the treatment of insulin resistance, diabetes, and diabetes-associated dyslipidemia |
| US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| EP3053440B1 (en) | 2007-04-11 | 2020-08-12 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US8142826B2 (en) | 2007-11-05 | 2012-03-27 | Naturex, Inc. | Extract of Fraxinus excelsior seeds and therapeutic applications therefor |
| US8883721B2 (en) * | 2009-05-12 | 2014-11-11 | Mcgill University | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| US9724381B2 (en) | 2009-05-12 | 2017-08-08 | The Administrators Of The Tulane Educational Fund | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| AU2011268256B8 (en) | 2010-06-16 | 2016-12-22 | Mcgill University | Growth hormone secretatogue receptor antagonists and uses thereof |
| EP3323818A1 (en) | 2010-09-22 | 2018-05-23 | Arena Pharmaceuticals, Inc. | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| PL3242666T3 (pl) | 2015-01-06 | 2025-02-17 | Arena Pharmaceuticals, Inc. | Związek do zastosowania w leczeniu dolegliwości związanych z receptorem s1p1 |
| BR112017027656B1 (pt) | 2015-06-22 | 2023-12-05 | Arena Pharmaceuticals, Inc. | Hábito cristalino de placa livre de sal de l-arginina de ácido (r)-2-(7-(4- ciclopentil-3-(trifluorometil)benzilóxi)- 1,2,3,4-tetra-hidrociclo-penta[b]indol-3- il)acético, composição farmacêutica que o compreende, seus usos e método de preparação do mesmo |
| MX2019009841A (es) | 2017-02-16 | 2020-01-30 | Arena Pharm Inc | Compuestos y metodos para el tratamiento de la colangitis biliar primaria. |
| KR101934197B1 (ko) * | 2017-06-12 | 2018-12-31 | 아주대학교산학협력단 | PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 |
| CA3102136A1 (en) | 2018-06-06 | 2019-12-12 | Arena Pharmaceuticals, Inc. | Methods of treating conditions related to the s1p1 receptor |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US5273999A (en) * | 1991-09-10 | 1993-12-28 | Hoffmann-La Roche Inc. | Carboxylic acid leukotriene B4 antagonists |
| PL351470A1 (en) * | 1999-04-28 | 2003-04-22 | Aventis Pharma Gmbh | Tri-aryl acid derivatives as ppar receptor ligands |
| FR2802808B1 (fr) * | 1999-12-22 | 2002-08-09 | Oreal | Utilisation de composes polycycliques aromatiques en tant qu'activateurs des recepteurs de type ppars dans une composition cosmetique ou pharmaceutique |
| JP2004513090A (ja) | 2000-09-27 | 2004-04-30 | メルク エンド カムパニー インコーポレーテッド | 糖尿病及び脂質異常症の治療のためのベンゾピランカルボン酸誘導体 |
| JP2002114781A (ja) * | 2000-10-06 | 2002-04-16 | Sankyo Co Ltd | 置換縮合イミダゾール誘導体を含有する糖尿病の予防剤、治療剤 |
-
2003
- 2003-07-25 EP EP03771947A patent/EP1539137B1/en not_active Expired - Lifetime
- 2003-07-25 JP JP2004524924A patent/JP4505327B2/ja not_active Expired - Fee Related
- 2003-07-25 AU AU2003256911A patent/AU2003256911B2/en not_active Ceased
- 2003-07-25 WO PCT/US2003/023499 patent/WO2004010992A1/en not_active Ceased
- 2003-07-25 CA CA002493913A patent/CA2493913A1/en not_active Abandoned
- 2003-07-25 US US10/522,646 patent/US7297715B2/en not_active Expired - Fee Related
- 2003-07-25 DE DE60332738T patent/DE60332738D1/de not_active Expired - Lifetime
- 2003-07-25 AT AT03771947T patent/ATE468851T1/de not_active IP Right Cessation
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