JP2005538109A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005538109A5 JP2005538109A5 JP2004524924A JP2004524924A JP2005538109A5 JP 2005538109 A5 JP2005538109 A5 JP 2005538109A5 JP 2004524924 A JP2004524924 A JP 2004524924A JP 2004524924 A JP2004524924 A JP 2004524924A JP 2005538109 A5 JP2005538109 A5 JP 2005538109A5
- Authority
- JP
- Japan
- Prior art keywords
- inhibitor
- compound
- pharmaceutical composition
- compound according
- agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 C*c(c(IC)c1)cc2c1OC(*)(*)[C@](C)C(*)C2*(C)C Chemical compound C*c(c(IC)c1)cc2c1OC(*)(*)[C@](C)C(*)C2*(C)C 0.000 description 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N c1ccccc1 Chemical compound c1ccccc1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39951802P | 2002-07-30 | 2002-07-30 | |
| PCT/US2003/023499 WO2004010992A1 (en) | 2002-07-30 | 2003-07-25 | Ppar alpha selective compounds for the treatment of dyslipidemia and other lipid disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005538109A JP2005538109A (ja) | 2005-12-15 |
| JP2005538109A5 true JP2005538109A5 (https=) | 2006-09-07 |
| JP4505327B2 JP4505327B2 (ja) | 2010-07-21 |
Family
ID=31188591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004524924A Expired - Fee Related JP4505327B2 (ja) | 2002-07-30 | 2003-07-25 | 異常脂血症および他の脂質障害の治療用のＰＰＡＲα選択的化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7297715B2 (https=) |
| EP (1) | EP1539137B1 (https=) |
| JP (1) | JP4505327B2 (https=) |
| AT (1) | ATE468851T1 (https=) |
| AU (1) | AU2003256911B2 (https=) |
| CA (1) | CA2493913A1 (https=) |
| DE (1) | DE60332738D1 (https=) |
| WO (1) | WO2004010992A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05007485A (es) | 2003-01-14 | 2006-01-30 | Arena Pharm Inc | Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia. |
| BRPI0409447A (pt) * | 2003-04-14 | 2006-04-18 | Inst For Pharm Discovery Inc | ácidos fenilalcanóicos substituìdos |
| CN1812977A (zh) | 2003-04-30 | 2006-08-02 | 药物研发有限责任公司 | 取代羧酸 |
| US7132426B2 (en) | 2003-07-14 | 2006-11-07 | Arena Pharmaceuticals, Inc. | Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto |
| AU2003267347A1 (en) * | 2003-09-10 | 2005-03-29 | Galapagos Genomics N.V. | Method of identifying a compound that changes the amyloid-beta precursor protein processing in a cell |
| EP1566202A1 (en) * | 2004-02-23 | 2005-08-24 | Sahltech I Göteborg AB | Use of resistin antagonists in the treatment of rheumatoid arthritis |
| MX2007001634A (es) * | 2004-08-11 | 2007-04-23 | Kyorin Seiyaku Kk | Nuevo derivado de acido amino benzoico ciclico. |
| MY148521A (en) | 2005-01-10 | 2013-04-30 | Arena Pharm Inc | Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto |
| CN101189231B (zh) * | 2005-03-23 | 2011-05-18 | 杏林制药株式会社 | 环状氨基苯基链烷酸衍生物 |
| WO2008091338A1 (en) * | 2007-01-23 | 2008-07-31 | Reddy Us Therapeutics, Inc. | Methods and compositions for the treatment of insulin resistance, diabetes, and diabetes-associated dyslipidemia |
| US11241420B2 (en) | 2007-04-11 | 2022-02-08 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US20160331729A9 (en) | 2007-04-11 | 2016-11-17 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| EP3788877B1 (en) | 2007-04-11 | 2024-08-07 | Omeros Corporation | Compositions and methods for prophylaxis and treatment of addictions |
| US8142826B2 (en) | 2007-11-05 | 2012-03-27 | Naturex, Inc. | Extract of Fraxinus excelsior seeds and therapeutic applications therefor |
| CA2761901C (en) * | 2009-05-12 | 2019-08-13 | The Administrators Of The Tulane Educational Fund | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| US9724381B2 (en) | 2009-05-12 | 2017-08-08 | The Administrators Of The Tulane Educational Fund | Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof |
| EP2582715B1 (en) | 2010-06-16 | 2018-11-28 | The Administrators of the Tulane Educational Fund | Growth hormone secretatogue receptor antagonists and uses thereof |
| PH12013500547A1 (en) | 2010-09-22 | 2013-06-10 | Arena Pharm Inc | Modulators of the gpr119 receptor and the treatment of disorders related thereto |
| MX386419B (es) | 2015-01-06 | 2025-03-18 | Arena Pharm Inc | Metodos de condiciones de tratamiento relacionadas con el receptor s1p1. |
| EP3939965A1 (en) | 2015-06-22 | 2022-01-19 | Arena Pharmaceuticals, Inc. | Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in sipi receptor-associated disorders |
| MA47504A (fr) | 2017-02-16 | 2019-12-25 | Arena Pharm Inc | Composés et méthodes de traitement de l'angiocholite biliaire primitive |
| KR101934197B1 (ko) * | 2017-06-12 | 2018-12-31 | 아주대학교산학협력단 | PPARα/γ 이중 작용 활성을 갖는 신규 화합물 및 이를 유효성분으로 함유하는 대사질환 예방 또는 치료용 조성물 |
| ES2987794T3 (es) | 2018-06-06 | 2024-11-18 | Arena Pharm Inc | Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4565882A (en) * | 1984-01-06 | 1986-01-21 | G. D. Searle & Co. | Substituted dihydrobenzopyran-2-carboxylates |
| US5273999A (en) * | 1991-09-10 | 1993-12-28 | Hoffmann-La Roche Inc. | Carboxylic acid leukotriene B4 antagonists |
| EP1177176B1 (en) * | 1999-04-28 | 2006-04-19 | Aventis Pharma Deutschland GmbH | Tri-aryl acid derivatives as ppar receptor ligands |
| FR2802808B1 (fr) * | 1999-12-22 | 2002-08-09 | Oreal | Utilisation de composes polycycliques aromatiques en tant qu'activateurs des recepteurs de type ppars dans une composition cosmetique ou pharmaceutique |
| AU2001292874B2 (en) * | 2000-09-27 | 2006-06-15 | Merck & Co., Inc. | Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders |
| JP2002114781A (ja) * | 2000-10-06 | 2002-04-16 | Sankyo Co Ltd | 置換縮合イミダゾール誘導体を含有する糖尿病の予防剤、治療剤 |
-
2003
- 2003-07-25 US US10/522,646 patent/US7297715B2/en not_active Expired - Fee Related
- 2003-07-25 AT AT03771947T patent/ATE468851T1/de not_active IP Right Cessation
- 2003-07-25 CA CA002493913A patent/CA2493913A1/en not_active Abandoned
- 2003-07-25 EP EP03771947A patent/EP1539137B1/en not_active Expired - Lifetime
- 2003-07-25 WO PCT/US2003/023499 patent/WO2004010992A1/en not_active Ceased
- 2003-07-25 AU AU2003256911A patent/AU2003256911B2/en not_active Ceased
- 2003-07-25 JP JP2004524924A patent/JP4505327B2/ja not_active Expired - Fee Related
- 2003-07-25 DE DE60332738T patent/DE60332738D1/de not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005538109A5 (https=) | ||
| CA2510540A1 (en) | Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1 | |
| CA2488592A1 (en) | 11-beta-hydroxysteroid dehydrogenase 1 inhibitors useful for the treatment of diabetes, obesity and dyslipidemia | |
| US7041837B2 (en) | Heterocyclic compounds having hypolipidemic, hypocholesteremic activities process for their preparation and pharmaceutical compositions containing them and their use in medicine | |
| JP2006500384A5 (https=) | ||
| JP5786034B2 (ja) | 脂質異常症の治療に適したヘテロ環式化合物 | |
| CA2525764A1 (en) | N-acyl nitrogen heterocycles as ligands of peroxisome proliferator-activated receptors | |
| JP2005511634A5 (https=) | ||
| HRP20241674T1 (hr) | 6'-[[(1s,3s)-3-[[5-(difluormetoksi)-2-pirimidinil]amino]ciklopentil]amino][1(2h),3'-bipiridin]-2-on kao inhibitor pcsk9 i postupci njegove upotrebe | |
| CA2463154A1 (en) | Heterocyclic compounds and methods of use | |
| JP2004513076A5 (https=) | ||
| US9572798B2 (en) | Therapeutic agent for dyslipidemia | |
| JP2006510630A5 (https=) | ||
| JP2016500063A5 (https=) | ||
| CA2502269A1 (en) | Beta-amino heterocyclic dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes | |
| JP2010529203A5 (https=) | ||
| WO2008035359A2 (en) | Oximinophenoxyalkanoic acid and phenylalkanoic acid derivatives | |
| WO2007099553A2 (en) | 1,3-dioxane carboxylic acids | |
| US9273041B2 (en) | Compounds for the treatment of dyslipidemia and related diseases | |
| US20150051144A1 (en) | Compounds for the treatment of dyslipidemia and other diseases | |
| CA2598725A1 (en) | Fused aromatic compounds having anti-diabetic activity | |
| NZ593361A (en) | Dipeptidyl peptidase iv inhibitors | |
| WO2014192023A1 (en) | Novel compounds suitable for the treatment of dyslipidemia | |
| Desai et al. | Design and synthesis of potent and subtype-selective PPARα agonists | |
| JP2008513458A (ja) | 異常脂質血症及び他の脂質障害の治療用化合物 |