JP2005538034A5 - - Google Patents
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- JP2005538034A5 JP2005538034A5 JP2003550745A JP2003550745A JP2005538034A5 JP 2005538034 A5 JP2005538034 A5 JP 2005538034A5 JP 2003550745 A JP2003550745 A JP 2003550745A JP 2003550745 A JP2003550745 A JP 2003550745A JP 2005538034 A5 JP2005538034 A5 JP 2005538034A5
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- JP
- Japan
- Prior art keywords
- kit
- dose
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108010002350 Interleukin-2 Proteins 0.000 claims 89
- 102000000588 Interleukin-2 Human genes 0.000 claims 89
- 230000003442 weekly effect Effects 0.000 claims 17
- 210000002966 serum Anatomy 0.000 claims 13
- 210000004027 cell Anatomy 0.000 claims 10
- 238000011282 treatment Methods 0.000 claims 7
- 238000012423 maintenance Methods 0.000 claims 6
- 238000011284 combination treatment Methods 0.000 claims 5
- 210000000822 natural killer cell Anatomy 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 101001002657 Homo sapiens Interleukin-2 Proteins 0.000 claims 4
- 208000028564 B-cell non-Hodgkin lymphoma Diseases 0.000 claims 3
- 102100022005 B-lymphocyte antigen CD20 Human genes 0.000 claims 2
- 101000897405 Homo sapiens B-lymphocyte antigen CD20 Proteins 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 230000004663 cell proliferation Effects 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims 1
- 238000002648 combination therapy Methods 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 102000055277 human IL2 Human genes 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1796801A | 2001-12-07 | 2001-12-07 | |
| US10/293,664 US20030185796A1 (en) | 2000-03-24 | 2002-11-12 | Methods of therapy for non-hodgkin's lymphoma |
| PCT/US2002/039253 WO2003049694A2 (en) | 2001-12-07 | 2002-12-06 | Methods of therapy for non-hodgkin's lymphoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005538034A JP2005538034A (ja) | 2005-12-15 |
| JP2005538034A5 true JP2005538034A5 (https=) | 2006-11-30 |
Family
ID=26690566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003550745A Withdrawn JP2005538034A (ja) | 2001-12-07 | 2002-12-06 | 非ホジキンリンパ腫の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1463524A4 (https=) |
| JP (1) | JP2005538034A (https=) |
| AU (1) | AU2002362098A1 (https=) |
| CA (1) | CA2469045A1 (https=) |
| WO (1) | WO2003049694A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI335821B (en) | 2002-12-16 | 2011-01-11 | Genentech Inc | Immunoglobulin variants and uses thereof |
| JP2007526220A (ja) | 2003-06-05 | 2007-09-13 | ジェネンテック・インコーポレーテッド | Ｂ細胞疾患の併用療法 |
| US8147832B2 (en) * | 2003-08-14 | 2012-04-03 | Merck Patent Gmbh | CD20-binding polypeptide compositions and methods |
| JP2007515185A (ja) * | 2003-12-22 | 2007-06-14 | カイロン コーポレイション | 免疫応答障害に対する処置ストラテジーのための診断法としてのＦｃレセプター多型の使用 |
| BRPI0511187A (pt) | 2004-05-20 | 2007-12-04 | Zymogenetics Inc | método para tratar cáncer em um indivìduo |
| AU2005249566B2 (en) | 2004-06-04 | 2010-11-11 | Genentech, Inc. | Method for treating multiple sclerosis |
| CA2597933A1 (en) * | 2005-02-15 | 2006-08-24 | Novartis Vaccines And Diagnostics, Inc. | Methods for treating lymphomas using a combination of a chemotherapeutic agent and il-2 and optionally an anti-cd20 antibody |
| ZA200709956B (en) | 2005-05-20 | 2009-02-25 | Genentech Inc | Pretreatment of a biological sample from an autoimmune disease subject |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| ES2618543T3 (es) | 2005-11-23 | 2017-06-21 | Genentech, Inc. | Métodos y composiciones relacionados con ensayos de linfocitos B |
| KR102055873B1 (ko) | 2007-07-09 | 2019-12-13 | 제넨테크, 인크. | 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지 |
| HUE030134T2 (en) | 2007-10-16 | 2017-04-28 | Zymogenetics Inc | Combination of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) and anti-CD20 agents for the treatment of autoimmune diseases |
| US7914785B2 (en) | 2008-01-02 | 2011-03-29 | Bergen Teknologieverforing As | B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| EP2077281A1 (en) | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| ATE548052T1 (de) * | 2008-01-17 | 2012-03-15 | Philogen Spa | Kombination aus einem anti-edb-fibronectin- antikörper-il-2-fusionsprotein und einem b-zellen bindenden molekül, b-zellen-vorläufern und/oder deren krebserregendem gegenspieler |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| HRP20200768T4 (hr) | 2009-08-11 | 2025-03-28 | F. Hoffmann - La Roche Ag | Proizvodnja proteina u mediju za uzgoj stanica bez glutamina |
| KR20130009760A (ko) | 2010-02-10 | 2013-01-23 | 이뮤노젠 아이엔씨 | Ｃｄ２０ 항체 및 이의 용도 |
| HUE057952T2 (hu) | 2015-06-24 | 2022-06-28 | Hoffmann La Roche | Anti-transzferrin receptor antitestek testreszabott affinitással |
| TWI873952B (zh) | 2015-10-02 | 2025-02-21 | 瑞士商赫孚孟拉羅股份公司 | 雙特異性抗‐人類cd20/人類轉鐵蛋白受體抗體及使用方法 |
| CN115369086B (zh) * | 2022-02-22 | 2023-05-12 | 北京景达生物科技有限公司 | 一种nk细胞扩大培养的培养方案 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003528155A (ja) * | 2000-03-24 | 2003-09-24 | カイロン コーポレイション | Ｃｄ２０に対する抗体とインターロイキン−２との組み合わせを用いる非ホジキンリンパ腫の治療方法 |
-
2002
- 2002-12-06 CA CA002469045A patent/CA2469045A1/en not_active Abandoned
- 2002-12-06 JP JP2003550745A patent/JP2005538034A/ja not_active Withdrawn
- 2002-12-06 WO PCT/US2002/039253 patent/WO2003049694A2/en not_active Ceased
- 2002-12-06 AU AU2002362098A patent/AU2002362098A1/en not_active Abandoned
- 2002-12-06 EP EP02797231A patent/EP1463524A4/en not_active Withdrawn
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