JP2005532815A5 - - Google Patents
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- Publication number
- JP2005532815A5 JP2005532815A5 JP2004521968A JP2004521968A JP2005532815A5 JP 2005532815 A5 JP2005532815 A5 JP 2005532815A5 JP 2004521968 A JP2004521968 A JP 2004521968A JP 2004521968 A JP2004521968 A JP 2004521968A JP 2005532815 A5 JP2005532815 A5 JP 2005532815A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- mrna
- target binding
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 108020004707 nucleic acids Proteins 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 8
- 102000039446 nucleic acids Human genes 0.000 claims 8
- 108020004999 messenger RNA Proteins 0.000 claims 6
- 230000009395 genetic defect Effects 0.000 claims 3
- 210000004927 skin cell Anatomy 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 230000014509 gene expression Effects 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/198,447 US20040018622A1 (en) | 2002-07-17 | 2002-07-17 | Spliceosome mediated RNA trans-splicing for correction of skin disorders |
| PCT/US2003/022469 WO2004006678A1 (en) | 2002-07-17 | 2003-07-17 | Spliceosome mediated rna trans-splicing for correction of skin disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005532815A JP2005532815A (ja) | 2005-11-04 |
| JP2005532815A5 true JP2005532815A5 (https=) | 2006-06-08 |
Family
ID=30115154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004521968A Withdrawn JP2005532815A (ja) | 2002-07-17 | 2003-07-17 | 皮膚疾患の修正のためのスプライセオソームにより媒介されるｒｎａトランススプライシング |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040018622A1 (https=) |
| EP (1) | EP1542532A1 (https=) |
| JP (1) | JP2005532815A (https=) |
| AU (1) | AU2003256606A1 (https=) |
| CA (1) | CA2492469A1 (https=) |
| WO (1) | WO2004006678A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1716165A4 (en) * | 2004-01-23 | 2008-06-18 | Virxsys Corp | EXPRESSION OF APOA-1 AND VARIANTS THEREOF, USING SPSSISSOSOM-MEDIATED RNA TRANS MIXING |
| CA2555965A1 (en) * | 2004-02-03 | 2005-08-18 | Hybrid Biosciences Pty Ltd | Method of identifying genes which promote hybrid vigour and hybrid debility and uses thereof |
| AU2005210679B2 (en) * | 2004-02-03 | 2009-10-01 | Hybrid Biosciences Pty Ltd | Method of identifying genes which promote hybrid vigour and hybrid debility and uses thereof |
| US20060134658A1 (en) * | 2004-08-09 | 2006-06-22 | Garcia-Blanco Mariano A | Use of RNA trans-splicing for generation of interfering RNA molecules |
| WO2007012138A1 (en) * | 2005-07-29 | 2007-02-01 | Hybrid Biosciences Pty Ltd | Identification of genes and their products which promote hybrid vigour or hybrid debility and uses thereof |
| KR100907106B1 (ko) | 2007-10-25 | 2009-07-09 | 국립암센터 | 라이보자임을 함유한 아데노바이러스를 이용한 질병의분자영상진단법 |
| JP5497006B2 (ja) | 2008-04-14 | 2014-05-21 | ザ ジェネラル ホスピタル コーポレイション | 膵管腺癌の検出および治療のためのプレクチン−１標的化剤 |
| EP2151248A1 (en) * | 2008-07-30 | 2010-02-10 | Johann Bauer | Improved pre-mRNA trans-splicing molecule (RTM) molecules and their uses |
| GB201219762D0 (en) | 2012-11-02 | 2012-12-19 | Bauer Johann | A RNA trans-splicing molecule (RTM) for use in the treatment of cancer |
| CA3005474A1 (en) | 2015-11-19 | 2017-05-26 | The Trustees Of The University Of Pennsylvania | Compositions and methods for correction of heritable ocular disease |
| KR102866133B1 (ko) | 2018-04-17 | 2025-09-30 | 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 | 트랜스-스플라이싱 분자 |
| EP4522758A4 (en) | 2022-05-13 | 2026-05-06 | Ascidian Therapeutics Inc | Abca4 trans-splicing molecules |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5914265A (en) * | 1992-04-30 | 1999-06-22 | Baylor College Of Medicine | Keratin K1 expression vectors and methods of use |
| US5874560A (en) * | 1994-04-22 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Melanoma antigens and their use in diagnostic and therapeutic methods |
| US5872241A (en) * | 1995-01-25 | 1999-02-16 | The Trustees Of Columbia University In The City Of New York | Multiple component RNA catalysts and uses thereof |
| US6280978B1 (en) * | 1995-12-15 | 2001-08-28 | Intronn Holdings, Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US6083702A (en) * | 1995-12-15 | 2000-07-04 | Intronn Holdings Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| ATE354957T1 (de) * | 1995-12-15 | 2006-03-15 | Intronn Inc | Durch trans-spaltung erhaltene therapeutische molekule |
-
2002
- 2002-07-17 US US10/198,447 patent/US20040018622A1/en not_active Abandoned
-
2003
- 2003-07-17 WO PCT/US2003/022469 patent/WO2004006678A1/en not_active Ceased
- 2003-07-17 US US10/621,867 patent/US20040248141A1/en not_active Abandoned
- 2003-07-17 JP JP2004521968A patent/JP2005532815A/ja not_active Withdrawn
- 2003-07-17 EP EP03764802A patent/EP1542532A1/en not_active Withdrawn
- 2003-07-17 CA CA002492469A patent/CA2492469A1/en not_active Abandoned
- 2003-07-17 AU AU2003256606A patent/AU2003256606A1/en not_active Abandoned
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