JP2005532051A - ヒト化抗リンホトキシンβレセプター抗体 - Google Patents
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- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023506750A (ja) * | 2019-12-11 | 2023-02-20 | シラグ・ゲーエムベーハー・インターナショナル | Ltbr及びedb結合ドメインを含む多重特異性結合分子並びにその使用 |
| JP2025500949A (ja) * | 2021-12-20 | 2025-01-15 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | アゴニストltbr抗体及びそれらを含む二重特異性抗体 |
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| US6312691B1 (en) * | 1996-01-26 | 2001-11-06 | Jeffrey L. Browning | Lymphotoxin-α/β complexes and anti-lympotoxin-β receptor antibodies as anti-tumor agents |
| US5925351A (en) | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
| ES2267294T3 (es) * | 1998-10-09 | 2007-03-01 | Biogen Idec Ma Inc. | Reversion del choque generalizado inducido por virus y de la disnea mediante el bloqueo de la ruta de la linfotoxina beta. |
| TR200602095T2 (tr) * | 2000-10-13 | 2007-02-21 | Biogen Idec Ma Inc. | Hümanize Anti-LT-Beta-R antikorları |
| AU2003299984A1 (en) * | 2002-12-20 | 2004-07-22 | Biogen Idec Ma Inc. | Multivalent lymphotoxin beta receptor agonists and therapeutic uses thereof |
| BR0317573A (pt) * | 2002-12-20 | 2005-11-22 | Biogen Idec Inc | Agentes de receptores de linfotoxina beta em combinação com agentes quimioterapêuticos |
| US20050163782A1 (en) * | 2003-06-27 | 2005-07-28 | Biogen Idec Ma Inc. | Modified binding molecules comprising connecting peptides |
| JP2005241389A (ja) * | 2004-02-25 | 2005-09-08 | Ochiyanomizu Jiyoshi Univ | 蛍光標識糖鎖の特異的固定化試薬および固定化方法 |
| KR20060132006A (ko) * | 2004-03-23 | 2006-12-20 | 비오겐 아이덱 엠에이 아이엔씨. | 수용체 커플링제 및 이의 치료적 용도 |
| WO2006074399A2 (en) * | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
| WO2008042436A2 (en) | 2006-10-03 | 2008-04-10 | Biogen Idec Ma Inc. | Biomarkers and assays for the treatment of cancer |
| BRPI0715580A2 (pt) | 2006-10-12 | 2014-06-10 | Genentech Inc | ''ANTICORPO ANTI-LINFOTOXINA-a (LTa) ISOLADO, ANTICORPO HUMANIZADO, ANTICORPOS ANTI-LINFOTOXINA-a,COMPOSIÇÃO DE ANTICORPO,ANTICORPO ANTI-IDIOTIPO,HIBRIDOMA,ANTICORPO,ÁCIDO NUCLÉICO ISOLADO, VETOR DE EXPRESSÃO,CÉLULA HOSPEDEIRA,MÉTODO DE PRODUÇÃO DE UM ANTICORPO,MÉTODO PARA INIBIR A PROLIFERAÇÃO CELULAR ATIVADA POR LTa, MÉTODO PARA TRATAR UM DISTURBIO AUTO-IMUNE, ARTIGOS MANUFATURADOS, MÉTODO PARA DIVULGAR UM ANTICORPO E MÉTODO PARA EMBALAR O ANTICORPO'' |
| KR20090071652A (ko) * | 2006-10-20 | 2009-07-01 | 바이오겐 아이덱 엠에이 인코포레이티드 | 가용성 림프독소-베타-수용체를 이용한 탈수초성 장애의 치료 |
| US8338376B2 (en) * | 2006-10-20 | 2012-12-25 | Biogen Idec Ma Inc. | Compositions comprising variant LT-B-R-IG fusion proteins |
| CA2689941C (en) | 2007-06-25 | 2019-10-29 | Esbatech Ag | Methods of modifying antibodies, and modified antibodies with improved functional properties |
| WO2010078526A1 (en) * | 2008-12-31 | 2010-07-08 | Biogen Idec Ma Inc. | Anti-lymphotoxin antibodies |
| US8481688B2 (en) | 2010-05-11 | 2013-07-09 | Aveo Pharmaceuticals, Inc. | Anti-FGFR2 antibodies |
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| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
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| US5925351A (en) * | 1995-07-21 | 1999-07-20 | Biogen, Inc. | Soluble lymphotoxin-β receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological disease |
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| TR200602095T2 (tr) | 2000-10-13 | 2007-02-21 | Biogen Idec Ma Inc. | Hümanize Anti-LT-Beta-R antikorları |
| BR0317573A (pt) | 2002-12-20 | 2005-11-22 | Biogen Idec Inc | Agentes de receptores de linfotoxina beta em combinação com agentes quimioterapêuticos |
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| KR20060132006A (ko) | 2004-03-23 | 2006-12-20 | 비오겐 아이덱 엠에이 아이엔씨. | 수용체 커플링제 및 이의 치료적 용도 |
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2003
- 2003-07-01 TW TW092117964A patent/TW200416044A/zh unknown
- 2003-07-01 AU AU2003248782A patent/AU2003248782A1/en not_active Abandoned
- 2003-07-01 CA CA002491480A patent/CA2491480A1/en not_active Abandoned
- 2003-07-01 EP EP03762296A patent/EP1539793A4/en not_active Withdrawn
- 2003-07-01 JP JP2004518186A patent/JP2005532051A/ja active Pending
- 2003-07-01 WO PCT/US2003/020762 patent/WO2004002431A2/en not_active Ceased
- 2003-07-01 NZ NZ537965A patent/NZ537965A/en unknown
- 2003-07-01 AR ARP030102391A patent/AR040367A1/es unknown
- 2003-07-01 CN CNA038207214A patent/CN1678625A/zh active Pending
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2004
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2023506750A (ja) * | 2019-12-11 | 2023-02-20 | シラグ・ゲーエムベーハー・インターナショナル | Ltbr及びedb結合ドメインを含む多重特異性結合分子並びにその使用 |
| JP2025500949A (ja) * | 2021-12-20 | 2025-01-15 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | アゴニストltbr抗体及びそれらを含む二重特異性抗体 |
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| US20060222644A1 (en) | 2006-10-05 |
| CN1678625A (zh) | 2005-10-05 |
| AR040367A1 (es) | 2005-03-30 |
| NZ537965A (en) | 2008-04-30 |
| EP1539793A4 (en) | 2006-02-01 |
| WO2004002431A2 (en) | 2004-01-08 |
| WO2004002431A3 (en) | 2004-08-26 |
| AU2003248782A1 (en) | 2004-01-19 |
| TW200416044A (en) | 2004-09-01 |
| EP1539793A2 (en) | 2005-06-15 |
| CA2491480A1 (en) | 2004-01-08 |
| US7429645B2 (en) | 2008-09-30 |
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