JP2005528921A - Cx3cr1修飾物質を用いる糖尿病の治療および診断の方法 - Google Patents

Cx3cr1修飾物質を用いる糖尿病の治療および診断の方法 Download PDF

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JP2005528921A
JP2005528921A JP2004511543A JP2004511543A JP2005528921A JP 2005528921 A JP2005528921 A JP 2005528921A JP 2004511543 A JP2004511543 A JP 2004511543A JP 2004511543 A JP2004511543 A JP 2004511543A JP 2005528921 A JP2005528921 A JP 2005528921A
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cx3cr1
polypeptide
seq
fractalkine
cell
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JP2005528921A5 (https=
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ショナ ムーディー
トーマス エー. グスタフソン
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メタボレックス インコーポレーティッド
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
JP2004511543A 2002-06-10 2003-06-10 Cx3cr1修飾物質を用いる糖尿病の治療および診断の方法 Withdrawn JP2005528921A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38769902P 2002-06-10 2002-06-10
PCT/US2003/018570 WO2003104484A1 (en) 2002-06-10 2003-06-10 Methods of treating and diagnosing diabetes with cx3cr1 modulators

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JP2005528921A true JP2005528921A (ja) 2005-09-29
JP2005528921A5 JP2005528921A5 (https=) 2006-08-10

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US (1) US20060160076A1 (https=)
EP (1) EP1511850A4 (https=)
JP (1) JP2005528921A (https=)
AU (1) AU2003243532A1 (https=)
CA (1) CA2487438A1 (https=)
WO (1) WO2003104484A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015514685A (ja) * 2012-03-01 2015-05-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 糖尿病および循環器病の診断および治療のための新たな標的

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005103684A2 (en) * 2004-04-20 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with cx3c chemokine receptor 1 (cx3cr1)
EP2023144A1 (en) * 2007-08-01 2009-02-11 Sanofi-Aventis Novel AS160-like protein, test systems, methods and uses involving it for the identification of diabetes type 2 therapeutics
KR101666228B1 (ko) 2007-09-28 2016-10-13 인트렉손 코포레이션 생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도
AU2013226340B2 (en) 2012-02-27 2017-06-22 Ablynx N.V. CX3CR1-binding polypeptides
WO2015026884A1 (en) * 2013-08-21 2015-02-26 Boehringer Ingelheim International Gmbh Cx3cr1-targeting imaging agents and their use in the diagnosis and treatment of disease
CN103656639B (zh) * 2013-12-18 2015-02-18 南方医科大学南方医院 不规则趋化因子的中和抗体用于制备消除糖尿病心肾功能损害不良代谢记忆的药物的用途
MA46568A (fr) 2016-10-24 2019-08-28 Novo Nordisk As Dosage biologique de formulations d'insuline
WO2025264930A1 (en) * 2024-06-19 2025-12-26 The Trustees Of The University Of Pennsylvania Compositions and methods for immune cell trafficking modulation

Family Cites Families (3)

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Publication number Priority date Publication date Assignee Title
US6107475A (en) * 1992-11-17 2000-08-22 Icos Corporation Seven transmembrane receptors
CA2128208C (en) * 1992-11-17 2004-01-06 Ronald Godiska Novel seven transmembrane receptors
US6699677B1 (en) * 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015514685A (ja) * 2012-03-01 2015-05-21 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 糖尿病および循環器病の診断および治療のための新たな標的

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Publication number Publication date
US20060160076A1 (en) 2006-07-20
CA2487438A1 (en) 2003-12-18
EP1511850A1 (en) 2005-03-09
EP1511850A4 (en) 2006-06-07
AU2003243532A1 (en) 2003-12-22
WO2003104484A1 (en) 2003-12-18

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