AU2003243532A1 - Methods of treating and diagnosing diabetes with cx3cr1 modulators - Google Patents

Methods of treating and diagnosing diabetes with cx3cr1 modulators Download PDF

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Publication number
AU2003243532A1
AU2003243532A1 AU2003243532A AU2003243532A AU2003243532A1 AU 2003243532 A1 AU2003243532 A1 AU 2003243532A1 AU 2003243532 A AU2003243532 A AU 2003243532A AU 2003243532 A AU2003243532 A AU 2003243532A AU 2003243532 A1 AU2003243532 A1 AU 2003243532A1
Authority
AU
Australia
Prior art keywords
cx3cr1
fractalkine
protein
cells
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003243532A
Other languages
English (en)
Inventor
Thomas A. Gustafson
Shonna Moodie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CymaBay Therapeutics Inc
Original Assignee
Metabolex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolex Inc filed Critical Metabolex Inc
Publication of AU2003243532A1 publication Critical patent/AU2003243532A1/en
Abandoned legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7158Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for chemokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AU2003243532A 2002-06-10 2003-06-10 Methods of treating and diagnosing diabetes with cx3cr1 modulators Abandoned AU2003243532A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US38769902P 2002-06-10 2002-06-10
US60/387,699 2002-06-10
PCT/US2003/018570 WO2003104484A1 (en) 2002-06-10 2003-06-10 Methods of treating and diagnosing diabetes with cx3cr1 modulators

Publications (1)

Publication Number Publication Date
AU2003243532A1 true AU2003243532A1 (en) 2003-12-22

Family

ID=29736354

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003243532A Abandoned AU2003243532A1 (en) 2002-06-10 2003-06-10 Methods of treating and diagnosing diabetes with cx3cr1 modulators

Country Status (6)

Country Link
US (1) US20060160076A1 (https=)
EP (1) EP1511850A4 (https=)
JP (1) JP2005528921A (https=)
AU (1) AU2003243532A1 (https=)
CA (1) CA2487438A1 (https=)
WO (1) WO2003104484A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005103684A2 (en) * 2004-04-20 2005-11-03 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with cx3c chemokine receptor 1 (cx3cr1)
EP2023144A1 (en) * 2007-08-01 2009-02-11 Sanofi-Aventis Novel AS160-like protein, test systems, methods and uses involving it for the identification of diabetes type 2 therapeutics
KR101666228B1 (ko) 2007-09-28 2016-10-13 인트렉손 코포레이션 생물치료학적 분자를 발현시키기 위한 치료학적 유전자-스위치 작제물 및 생물반응기, 및 이의 용도
AU2013226340B2 (en) 2012-02-27 2017-06-22 Ablynx N.V. CX3CR1-binding polypeptides
EP2820426A4 (en) * 2012-03-01 2015-07-29 Univ California NOVEL TARGET MOLECULE FOR THE DIAGNOSIS AND TREATMENT OF DIABETES AND HEART CIRCULAR DISEASES
WO2015026884A1 (en) * 2013-08-21 2015-02-26 Boehringer Ingelheim International Gmbh Cx3cr1-targeting imaging agents and their use in the diagnosis and treatment of disease
CN103656639B (zh) * 2013-12-18 2015-02-18 南方医科大学南方医院 不规则趋化因子的中和抗体用于制备消除糖尿病心肾功能损害不良代谢记忆的药物的用途
MA46568A (fr) 2016-10-24 2019-08-28 Novo Nordisk As Dosage biologique de formulations d'insuline
WO2025264930A1 (en) * 2024-06-19 2025-12-26 The Trustees Of The University Of Pennsylvania Compositions and methods for immune cell trafficking modulation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107475A (en) * 1992-11-17 2000-08-22 Icos Corporation Seven transmembrane receptors
CA2128208C (en) * 1992-11-17 2004-01-06 Ronald Godiska Novel seven transmembrane receptors
US6699677B1 (en) * 1999-12-20 2004-03-02 Chemocentryx, Inc. Tethered ligands and methods of use

Also Published As

Publication number Publication date
US20060160076A1 (en) 2006-07-20
CA2487438A1 (en) 2003-12-18
EP1511850A1 (en) 2005-03-09
JP2005528921A (ja) 2005-09-29
EP1511850A4 (en) 2006-06-07
WO2003104484A1 (en) 2003-12-18

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Legal Events

Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period