JP2005528912A5 - - Google Patents
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- Publication number
- JP2005528912A5 JP2005528912A5 JP2004511476A JP2004511476A JP2005528912A5 JP 2005528912 A5 JP2005528912 A5 JP 2005528912A5 JP 2004511476 A JP2004511476 A JP 2004511476A JP 2004511476 A JP2004511476 A JP 2004511476A JP 2005528912 A5 JP2005528912 A5 JP 2005528912A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- acid molecule
- mrna
- trans
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108020004707 nucleic acids Proteins 0.000 claims 5
- 150000007523 nucleic acids Chemical class 0.000 claims 5
- 102000039446 nucleic acids Human genes 0.000 claims 5
- 108020004999 messenger RNA Proteins 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 230000007547 defect Effects 0.000 claims 2
- 210000000130 stem cell Anatomy 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 230000009395 genetic defect Effects 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38659402P | 2002-06-05 | 2002-06-05 | |
| PCT/US2003/017954 WO2003104416A2 (en) | 2002-06-05 | 2003-06-05 | Spliceosome mediated rna trans-splicing in stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005528912A JP2005528912A (ja) | 2005-09-29 |
| JP2005528912A5 true JP2005528912A5 (https=) | 2006-03-02 |
Family
ID=29736184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004511476A Pending JP2005528912A (ja) | 2002-06-05 | 2003-06-05 | 幹細胞におけるスプライセオソーム介在ｒｎａトランススプライシング |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040180429A1 (https=) |
| EP (1) | EP1549755A4 (https=) |
| JP (1) | JP2005528912A (https=) |
| AU (1) | AU2003247505A1 (https=) |
| CA (1) | CA2488249A1 (https=) |
| WO (1) | WO2003104416A2 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007518423A (ja) * | 2004-01-23 | 2007-07-12 | イントロン、インコーポレイテッド | スプライセオソーム仲介型ｒｎａトランススプライシングを使用するアポａ−１及びその変異体の発現 |
| EP2151248A1 (en) * | 2008-07-30 | 2010-02-10 | Johann Bauer | Improved pre-mRNA trans-splicing molecule (RTM) molecules and their uses |
| EP3377116A4 (en) | 2015-11-19 | 2019-07-10 | The Trustees of The University of Pennsylvania | COMPOSITIONS AND METHODS FOR CORRECTING ECG-RELATED EYE DISEASE |
| CA3097004A1 (en) | 2018-04-17 | 2019-10-24 | The Trustees Of The University Of Pennsylvania | Trans-splicing molecules |
| JP2023535381A (ja) * | 2020-07-17 | 2023-08-17 | グリーンライト バイオサイエンシーズ インコーポレーテッド | 遺伝子疾患の核酸治療薬 |
| AU2023208612A1 (en) * | 2022-01-18 | 2024-08-08 | National University Of Singapore | TRANS-SPLICING RNA (tsRNA) |
| AU2023269865A1 (en) | 2022-05-13 | 2024-11-21 | Ascidian Therapeutics, Inc. | Abca4 trans-splicing molecules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ241311A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Rna sequence having trans-splicing activity, plant strains |
| US6280978B1 (en) * | 1995-12-15 | 2001-08-28 | Intronn Holdings, Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US6083702A (en) * | 1995-12-15 | 2000-07-04 | Intronn Holdings Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| DE69636937T3 (de) * | 1995-12-15 | 2011-01-05 | Virxsys Corp. | Durch trans-spaltung erhaltene therapeutische molekule |
| CA2278734A1 (en) * | 1997-01-23 | 1998-07-30 | Immusol Incorporated | Gene functional analysis and discovery using randomized or target-specific ribozyme gene vector libraries |
-
2003
- 2003-06-05 AU AU2003247505A patent/AU2003247505A1/en not_active Abandoned
- 2003-06-05 US US10/456,273 patent/US20040180429A1/en not_active Abandoned
- 2003-06-05 EP EP03757404A patent/EP1549755A4/en not_active Withdrawn
- 2003-06-05 CA CA002488249A patent/CA2488249A1/en not_active Abandoned
- 2003-06-05 WO PCT/US2003/017954 patent/WO2003104416A2/en not_active Ceased
- 2003-06-05 JP JP2004511476A patent/JP2005528912A/ja active Pending
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