JP2005528912A - 幹細胞におけるスプライセオソーム介在ｒｎａトランススプライシング - Google Patents
幹細胞におけるスプライセオソーム介在ｒｎａトランススプライシング Download PDFInfo
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0688—Cells from the lungs or the respiratory tract
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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| US38659402P | 2002-06-05 | 2002-06-05 | |
| PCT/US2003/017954 WO2003104416A2 (en) | 2002-06-05 | 2003-06-05 | Spliceosome mediated rna trans-splicing in stem cells |
Publications (2)
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| JP2005528912A true JP2005528912A (ja) | 2005-09-29 |
| JP2005528912A5 JP2005528912A5 (enExample) | 2006-03-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| JP2004511476A Pending JP2005528912A (ja) | 2002-06-05 | 2003-06-05 | 幹細胞におけるスプライセオソーム介在ｒｎａトランススプライシング |
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| Country | Link |
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| US (1) | US20040180429A1 (enExample) |
| EP (1) | EP1549755A4 (enExample) |
| JP (1) | JP2005528912A (enExample) |
| AU (1) | AU2003247505A1 (enExample) |
| CA (1) | CA2488249A1 (enExample) |
| WO (1) | WO2003104416A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116171326A (zh) * | 2020-07-17 | 2023-05-26 | 绿光生物科技股份有限公司 | 用于基因病症的核酸疗法 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| AU2005207053A1 (en) * | 2004-01-23 | 2005-08-04 | Virxsys Corporation | Expression of ApoA-1 and variants thereof using spliceosome mediated RNA trans-splicing |
| EP2151248A1 (en) * | 2008-07-30 | 2010-02-10 | Johann Bauer | Improved pre-mRNA trans-splicing molecule (RTM) molecules and their uses |
| US10987433B2 (en) | 2015-11-19 | 2021-04-27 | The Trustees Of The University Of Pennsylvania | Compositions and methods for correction of heritable ocular disease |
| EP3781213A4 (en) | 2018-04-17 | 2022-10-19 | The Trustees of the University of Pennsylvania | TRANS-SPLICE MOLECULES |
| CN118786214A (zh) * | 2022-01-18 | 2024-10-15 | 新加坡国立大学 | 反式剪接RNA（tsRNA） |
| CA3252043A1 (en) | 2022-05-13 | 2023-11-16 | Ascidian Therapeutics, Inc. | ABCA4 TRANS-SPLICING MOLECULES |
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| NZ241311A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Rna sequence having trans-splicing activity, plant strains |
| US6280978B1 (en) * | 1995-12-15 | 2001-08-28 | Intronn Holdings, Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US6083702A (en) * | 1995-12-15 | 2000-07-04 | Intronn Holdings Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| AU730305B2 (en) * | 1995-12-15 | 2001-03-01 | Intronn Llc | Therapeutic molecules generated by trans-splicing |
| CA2278734A1 (en) * | 1997-01-23 | 1998-07-30 | Immusol Incorporated | Gene functional analysis and discovery using randomized or target-specific ribozyme gene vector libraries |
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- 2003-06-05 JP JP2004511476A patent/JP2005528912A/ja active Pending
- 2003-06-05 WO PCT/US2003/017954 patent/WO2003104416A2/en not_active Ceased
- 2003-06-05 EP EP03757404A patent/EP1549755A4/en not_active Withdrawn
- 2003-06-05 US US10/456,273 patent/US20040180429A1/en not_active Abandoned
- 2003-06-05 AU AU2003247505A patent/AU2003247505A1/en not_active Abandoned
- 2003-06-05 CA CA002488249A patent/CA2488249A1/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116171326A (zh) * | 2020-07-17 | 2023-05-26 | 绿光生物科技股份有限公司 | 用于基因病症的核酸疗法 |
| US12397012B2 (en) | 2020-07-17 | 2025-08-26 | Greenlight Biosciences, Inc. | Nucleic acid therapeutics for genetic disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1549755A4 (en) | 2006-09-20 |
| EP1549755A2 (en) | 2005-07-06 |
| US20040180429A1 (en) | 2004-09-16 |
| WO2003104416A3 (en) | 2004-07-01 |
| AU2003247505A1 (en) | 2003-12-22 |
| WO2003104416A2 (en) | 2003-12-18 |
| CA2488249A1 (en) | 2003-12-18 |
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