CA2488249A1 - Spliceosome mediated rna trans-splicing in stem cells - Google Patents
Spliceosome mediated rna trans-splicing in stem cells Download PDFInfo
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- CA2488249A1 CA2488249A1 CA002488249A CA2488249A CA2488249A1 CA 2488249 A1 CA2488249 A1 CA 2488249A1 CA 002488249 A CA002488249 A CA 002488249A CA 2488249 A CA2488249 A CA 2488249A CA 2488249 A1 CA2488249 A1 CA 2488249A1
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- stem cell
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0688—Cells from the lungs or the respiratory tract
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38659402P | 2002-06-05 | 2002-06-05 | |
| US60/386,594 | 2002-06-05 | ||
| PCT/US2003/017954 WO2003104416A2 (en) | 2002-06-05 | 2003-06-05 | Spliceosome mediated rna trans-splicing in stem cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2488249A1 true CA2488249A1 (en) | 2003-12-18 |
Family
ID=29736184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002488249A Abandoned CA2488249A1 (en) | 2002-06-05 | 2003-06-05 | Spliceosome mediated rna trans-splicing in stem cells |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20040180429A1 (enExample) |
| EP (1) | EP1549755A4 (enExample) |
| JP (1) | JP2005528912A (enExample) |
| AU (1) | AU2003247505A1 (enExample) |
| CA (1) | CA2488249A1 (enExample) |
| WO (1) | WO2003104416A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005207053A1 (en) * | 2004-01-23 | 2005-08-04 | Virxsys Corporation | Expression of ApoA-1 and variants thereof using spliceosome mediated RNA trans-splicing |
| EP2151248A1 (en) * | 2008-07-30 | 2010-02-10 | Johann Bauer | Improved pre-mRNA trans-splicing molecule (RTM) molecules and their uses |
| US10987433B2 (en) | 2015-11-19 | 2021-04-27 | The Trustees Of The University Of Pennsylvania | Compositions and methods for correction of heritable ocular disease |
| EP3781213A4 (en) | 2018-04-17 | 2022-10-19 | The Trustees of the University of Pennsylvania | TRANS-SPLICE MOLECULES |
| WO2022016077A1 (en) * | 2020-07-17 | 2022-01-20 | Greenlight Biosciences, Inc. | Nucleic acid therapeutics for genetic disorders |
| CN118786214A (zh) * | 2022-01-18 | 2024-10-15 | 新加坡国立大学 | 反式剪接RNA（tsRNA） |
| CA3252043A1 (en) | 2022-05-13 | 2023-11-16 | Ascidian Therapeutics, Inc. | ABCA4 TRANS-SPLICING MOLECULES |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ241311A (en) * | 1991-01-17 | 1995-03-28 | Gen Hospital Corp | Rna sequence having trans-splicing activity, plant strains |
| US6280978B1 (en) * | 1995-12-15 | 2001-08-28 | Intronn Holdings, Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| US6083702A (en) * | 1995-12-15 | 2000-07-04 | Intronn Holdings Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| AU730305B2 (en) * | 1995-12-15 | 2001-03-01 | Intronn Llc | Therapeutic molecules generated by trans-splicing |
| CA2278734A1 (en) * | 1997-01-23 | 1998-07-30 | Immusol Incorporated | Gene functional analysis and discovery using randomized or target-specific ribozyme gene vector libraries |
-
2003
- 2003-06-05 JP JP2004511476A patent/JP2005528912A/ja active Pending
- 2003-06-05 WO PCT/US2003/017954 patent/WO2003104416A2/en not_active Ceased
- 2003-06-05 EP EP03757404A patent/EP1549755A4/en not_active Withdrawn
- 2003-06-05 US US10/456,273 patent/US20040180429A1/en not_active Abandoned
- 2003-06-05 AU AU2003247505A patent/AU2003247505A1/en not_active Abandoned
- 2003-06-05 CA CA002488249A patent/CA2488249A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1549755A4 (en) | 2006-09-20 |
| EP1549755A2 (en) | 2005-07-06 |
| JP2005528912A (ja) | 2005-09-29 |
| US20040180429A1 (en) | 2004-09-16 |
| WO2003104416A3 (en) | 2004-07-01 |
| AU2003247505A1 (en) | 2003-12-22 |
| WO2003104416A2 (en) | 2003-12-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |