JP2005526768A - 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 - Google Patents

炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 Download PDF

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JP2005526768A
JP2005526768A JP2003575886A JP2003575886A JP2005526768A JP 2005526768 A JP2005526768 A JP 2005526768A JP 2003575886 A JP2003575886 A JP 2003575886A JP 2003575886 A JP2003575886 A JP 2003575886A JP 2005526768 A JP2005526768 A JP 2005526768A
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cyclic
saturated
unsaturated
inflammatory
branched
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JP2005526768A5 (enExample
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ガルゾン、アーロン
エイブラハム、アイェレット
フィンク、ジョージ
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ファーモス コーポレイション
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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JP2003575886A 2002-03-18 2003-03-16 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体 Abandoned JP2005526768A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL14873602A IL148736A0 (en) 2002-03-18 2002-03-18 Dexanabinol and dexanabinol analogs which regulate inflammation related genes
PCT/IL2003/000223 WO2003077832A2 (en) 2002-03-18 2003-03-16 Dexanabinol and dexanabinol analogs regulate inflammation related genes

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Publication Number Publication Date
JP2005526768A true JP2005526768A (ja) 2005-09-08
JP2005526768A5 JP2005526768A5 (enExample) 2006-01-26

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JP2003575886A Abandoned JP2005526768A (ja) 2002-03-18 2003-03-16 炎症関連遺伝子を調節するデキサナビノール及びデキサナビノール類似体

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EP (1) EP1485083A4 (enExample)
JP (1) JP2005526768A (enExample)
AU (1) AU2003214608A1 (enExample)
CA (1) CA2479676A1 (enExample)
IL (1) IL148736A0 (enExample)
WO (1) WO2003077832A2 (enExample)
ZA (1) ZA200407182B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010532782A (ja) * 2007-07-06 2010-10-14 イー セラピューティクス ピー エル シー メラノーマの治療
JP2013504550A (ja) * 2009-09-10 2013-02-07 イー セラピューティクス ピー エル シー 癌細胞アポトーシス
JP2017031120A (ja) * 2015-08-05 2017-02-09 オリザ油化株式会社 ＴＮＦ−α及びＩＬ−６産生抑制剤及びそれを用いた筋肉炎症抑制剤
WO2018163716A1 (ja) * 2017-03-08 2018-09-13 日清オイリオグループ株式会社 抗炎症剤、抗炎症用医薬組成物、抗炎症用食品組成物

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0326393D0 (en) * 2003-11-12 2003-12-17 Ares Trading Sa Cytokine antagonist molecules
EP1774328A1 (en) * 2004-07-23 2007-04-18 Novartis AG Biomarkers for rheumatoid arthritis (ra)
US20080262079A1 (en) * 2004-08-09 2008-10-23 Bernard Mach Cannabinoid Compositions and Methods of Use Thereof
HRP20090646T1 (hr) * 2005-03-17 2010-01-31 Proyecto De Biomedicina Cima Uporaba 5'-metiltioadenozina (mta) kod prevencije i/ili liječenja autoimunih bolesti i/ili odbacivanje transplantata
EP1752149A1 (en) * 2005-07-29 2007-02-14 Laboratorios Del Dr. Esteve, S.A. CB1 Antagonists or inverse agonists as therapeutical agents for the treatment of inflammation involving gene expression
PT1903866E (pt) * 2005-11-07 2016-06-09 Murty Pharmaceuticals Inc Distribuição melhorada de tetra-hidrocanabinol
CN102851295B (zh) * 2006-08-28 2015-01-07 长春华普生物技术有限公司 Toll 样受体调节性寡核苷酸及其用途
GB0719771D0 (en) * 2007-10-10 2007-11-21 Therapeutics Ltd E Dexanabinol in combination with inhibitors of BRAF or MEK for the treatment of melanoma
GB201207305D0 (en) 2012-04-26 2012-06-13 E Therapeutics Plc Therapy
WO2014021455A1 (ja) * 2012-08-03 2014-02-06 国立大学法人愛媛大学 免疫細胞の活性化抑制剤およびその用途
WO2017068349A1 (en) 2015-10-23 2017-04-27 E-Therapeutics Plc Cannabinoid for use in immunotherapy

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115245A (en) * 1995-09-11 2002-12-01 Yissum Res Dev Co Tumor necrosis factor inhibiting pharmaceuticals
CA2411585A1 (en) * 2000-06-22 2001-12-27 Pharmos Corporation Novel non-psychotropic cannabinoids

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010532782A (ja) * 2007-07-06 2010-10-14 イー セラピューティクス ピー エル シー メラノーマの治療
JP2013504550A (ja) * 2009-09-10 2013-02-07 イー セラピューティクス ピー エル シー 癌細胞アポトーシス
JP2015214579A (ja) * 2009-09-10 2015-12-03 イー セラピューティクス ピー エル シーＥ−Ｔｈｅｒａｐｅｕｔｉｃｓ Ｐｌｃ 癌細胞アポトーシス
JP2017031120A (ja) * 2015-08-05 2017-02-09 オリザ油化株式会社 ＴＮＦ−α及びＩＬ−６産生抑制剤及びそれを用いた筋肉炎症抑制剤
WO2018163716A1 (ja) * 2017-03-08 2018-09-13 日清オイリオグループ株式会社 抗炎症剤、抗炎症用医薬組成物、抗炎症用食品組成物

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Publication number Publication date
WO2003077832A2 (en) 2003-09-25
CA2479676A1 (en) 2003-09-25
ZA200407182B (en) 2006-02-22
EP1485083A4 (en) 2008-11-19
EP1485083A2 (en) 2004-12-15
AU2003214608A1 (en) 2003-09-29
WO2003077832A3 (en) 2003-12-31
IL148736A0 (en) 2002-09-12

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