JP2005526728A5 - - Google Patents
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- Publication number
- JP2005526728A5 JP2005526728A5 JP2003569201A JP2003569201A JP2005526728A5 JP 2005526728 A5 JP2005526728 A5 JP 2005526728A5 JP 2003569201 A JP2003569201 A JP 2003569201A JP 2003569201 A JP2003569201 A JP 2003569201A JP 2005526728 A5 JP2005526728 A5 JP 2005526728A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical formula
- dihydrexidine
- dopamine
- optionally substituted
- substituted derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000126 substance Substances 0.000 description 4
- BGOQGUHWXBGXJW-YOEHRIQHSA-N (6as,12br)-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridine-10,11-diol Chemical compound N1CC2=CC=CC=C2[C@@H]2[C@@H]1CCC1=C2C=C(O)C(O)=C1 BGOQGUHWXBGXJW-YOEHRIQHSA-N 0.000 description 2
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 description 2
- 239000000556 agonist Substances 0.000 description 1
- -1 dinaphtholine Chemical compound 0.000 description 1
- 229960003638 dopamine Drugs 0.000 description 1
- 239000000510 dopamine 1 receptor stimulating agent Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0200478A SE0200478D0 (sv) | 2002-02-15 | 2002-02-15 | Mono-ester and asymmetrically substituted di-ester pro-drugs of the dopamine D1 receptor agonist A-86929 |
| SE0200474A SE0200474D0 (sv) | 2002-02-17 | 2002-02-17 | Mono-ester and asymmetrically substituted di-ester pro-drugs of the dopamine D1 receptor agonists Dihydrexidine and Dinapsoline |
| PCT/US2003/004592 WO2003070245A1 (en) | 2002-02-15 | 2003-02-14 | Mono-ester and asymmetrically substituted di-ester pro-drugs of the dopamine d1 receptor agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005526728A JP2005526728A (ja) | 2005-09-08 |
| JP2005526728A5 true JP2005526728A5 (https=) | 2006-11-16 |
Family
ID=27759833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003569201A Pending JP2005526728A (ja) | 2002-02-15 | 2003-02-14 | ドーパミンｄ１受容体アゴニストのモノエステルプロドラッグおよび非対称置換ジエステルプロドラッグ |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7220754B2 (https=) |
| EP (1) | EP1480647B1 (https=) |
| JP (1) | JP2005526728A (https=) |
| AT (1) | ATE406896T1 (https=) |
| AU (1) | AU2003217430B2 (https=) |
| CA (1) | CA2476115A1 (https=) |
| DE (1) | DE60323339D1 (https=) |
| DK (1) | DK1480647T3 (https=) |
| ES (1) | ES2314189T3 (https=) |
| NO (1) | NO20043634L (https=) |
| WO (1) | WO2003070245A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9046537B2 (en) | 2003-09-22 | 2015-06-02 | Enzo Biochem, Inc. | Method for treating inflammation by administering a compound which binds LDL-receptor-related protein (LRP) ligand binding domain |
| EP1699450A4 (en) * | 2003-12-23 | 2009-11-11 | Darpharma Inc | Simultaneous administration of dopamine receptor bindings |
| US9052324B2 (en) | 2004-05-19 | 2015-06-09 | Enzo Biochem, Inc. | Compounds and assays for controlling Wnt activity |
| US8596306B2 (en) * | 2005-10-27 | 2013-12-03 | Synthetic Gas Solutions, Llc | Perfluorocarbon gas insufflation |
| NZ570606A (en) * | 2006-02-21 | 2011-11-25 | Purdue Research Foundation | Trans-fused chromenoisoquinolines, synthesis and methods for use |
| WO2010124005A1 (en) | 2009-04-21 | 2010-10-28 | Purdue Research Foundation | Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor |
| BR112015010620A2 (pt) * | 2012-11-08 | 2017-07-11 | Pfizer | compostos heteroaromáticos e seus usos como ligantes de dopamina d1 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4340600A (en) * | 1980-05-22 | 1982-07-20 | Smithkline Corporation | Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines |
| US4282227A (en) * | 1980-05-22 | 1981-08-04 | Smithkline Corporation | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| JPH02138A (ja) * | 1987-09-18 | 1990-01-05 | Banyu Pharmaceut Co Ltd | Ｌ‐ドーパ誘導体 |
| US5047536A (en) * | 1989-03-17 | 1991-09-10 | Purdue Research Foundation | Hexahydrobenzo(A)phenanthridine compounds |
| IE912999A1 (en) * | 1990-09-07 | 1992-03-11 | Abbott Lab | Phenanthridine compounds |
| WO1993024462A1 (en) * | 1992-05-26 | 1993-12-09 | Purdue Research Foundation | Substituted-hexahydrobenzo[a]phenanthridines |
| FI954738A7 (fi) * | 1993-04-06 | 1995-12-05 | Abbott Lab | Tetrasykliini yhdisteet dopamiiniagonisteina |
| EP0773933A1 (en) * | 1994-07-15 | 1997-05-21 | Purdue Research Foundation | Optically active isomers of dihydrexidine and its substituted analogs |
| MX9801179A (es) * | 1995-08-18 | 1998-04-30 | Purdue Research Foundation | Isoquinolinas fusionadas, novedosas como ligandos del receptor de dopamina. |
-
2003
- 2003-02-14 DE DE60323339T patent/DE60323339D1/de not_active Expired - Fee Related
- 2003-02-14 JP JP2003569201A patent/JP2005526728A/ja active Pending
- 2003-02-14 US US10/503,796 patent/US7220754B2/en not_active Expired - Fee Related
- 2003-02-14 DK DK03713475T patent/DK1480647T3/da active
- 2003-02-14 CA CA002476115A patent/CA2476115A1/en not_active Abandoned
- 2003-02-14 AT AT03713475T patent/ATE406896T1/de not_active IP Right Cessation
- 2003-02-14 WO PCT/US2003/004592 patent/WO2003070245A1/en not_active Ceased
- 2003-02-14 ES ES03713475T patent/ES2314189T3/es not_active Expired - Lifetime
- 2003-02-14 AU AU2003217430A patent/AU2003217430B2/en not_active Ceased
- 2003-02-14 EP EP03713475A patent/EP1480647B1/en not_active Expired - Lifetime
-
2004
- 2004-08-31 NO NO20043634A patent/NO20043634L/no unknown
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