JP2005524384A - ゲノム核酸におけるランダム分布反復配列への検出可能なプローブ結合の抑制に関する方法、キットおよび組成物 - Google Patents

ゲノム核酸におけるランダム分布反復配列への検出可能なプローブ結合の抑制に関する方法、キットおよび組成物 Download PDF

Info

Publication number
JP2005524384A
JP2005524384A JP2003530893A JP2003530893A JP2005524384A JP 2005524384 A JP2005524384 A JP 2005524384A JP 2003530893 A JP2003530893 A JP 2003530893A JP 2003530893 A JP2003530893 A JP 2003530893A JP 2005524384 A JP2005524384 A JP 2005524384A
Authority
JP
Japan
Prior art keywords
seq
probe
nucleic acid
sequence
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003530893A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005524384A5 (enExample
Inventor
カートセン,ニールセン,ブイ.
ハイルディグ−ニールセン,イェンス,ジェイ.
ウィリアムズ,ブレット,エフ.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dako Denmark ApS
Original Assignee
DakoCytomation Denmark AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DakoCytomation Denmark AS filed Critical DakoCytomation Denmark AS
Publication of JP2005524384A publication Critical patent/JP2005524384A/ja
Publication of JP2005524384A5 publication Critical patent/JP2005524384A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP2003530893A 2001-09-24 2002-09-24 ゲノム核酸におけるランダム分布反復配列への検出可能なプローブ結合の抑制に関する方法、キットおよび組成物 Pending JP2005524384A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32449901P 2001-09-24 2001-09-24
PCT/US2002/030573 WO2003027328A2 (en) 2001-09-24 2002-09-24 Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid

Publications (2)

Publication Number Publication Date
JP2005524384A true JP2005524384A (ja) 2005-08-18
JP2005524384A5 JP2005524384A5 (enExample) 2006-01-05

Family

ID=23263855

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003530893A Pending JP2005524384A (ja) 2001-09-24 2002-09-24 ゲノム核酸におけるランダム分布反復配列への検出可能なプローブ結合の抑制に関する方法、キットおよび組成物

Country Status (4)

Country Link
US (5) US20030129626A1 (enExample)
EP (1) EP1432826B1 (enExample)
JP (1) JP2005524384A (enExample)
WO (1) WO2003027328A2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006242618A (ja) * 2005-03-01 2006-09-14 Univ Of Tokyo 組織fish法によるテロメア量を指標とした癌の診断
JP2012040029A (ja) * 2006-08-08 2012-03-01 Arkray Inc 変異の検出方法およびそれに用いるキット
WO2017138500A1 (ja) * 2016-02-09 2017-08-17 公益財団法人がん研究会 希少造血器腫瘍の診断マーカー、検査方法、治療薬及びスクリーニング方法
WO2018101375A1 (ja) * 2016-11-30 2018-06-07 国立大学法人秋田大学 ヒトゲノムdna検出方法

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0878552A1 (en) 1997-05-13 1998-11-18 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
EP1078098A1 (en) 1998-05-04 2001-02-28 Dako A/S Method and probes for the detection of chromosome aberrations
US20030129626A1 (en) * 2001-09-24 2003-07-10 Nielsen Kirsten Vang Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid
EP1687451A2 (en) * 2003-09-30 2006-08-09 Applera Corporation Methods and kits for hybridizing multiple probe panels to nucleic acid samples
US7235459B2 (en) * 2004-08-31 2007-06-26 Micron Technology, Inc. Methods of forming trench isolation in the fabrication of integrated circuitry, methods of fabricating memory circuitry, integrated circuitry and memory integrated circuitry
CA2623405C (en) 2005-09-20 2014-11-25 Immunivest Corporation Methods and composition to generate unique sequence dna probes labeling of dna probes and the use of these probes
US9134237B2 (en) 2005-09-20 2015-09-15 Janssen Diagnotics, LLC High sensitivity multiparameter method for rare event analysis in a biological sample
AU2006327111A1 (en) * 2005-11-18 2007-06-28 The Children's Mercy Hospital Mitigation of Cot-1 DNA distortion in nucleic acid hybridization
US20070238104A1 (en) * 2006-04-07 2007-10-11 Agilent Technologies, Inc. Competitive oligonucleotides
US7618781B2 (en) * 2006-05-12 2009-11-17 Mayo Foundation For Medical Education And Research Nucleic acids for detecting B-cell malignancy
US20080131880A1 (en) * 2006-11-22 2008-06-05 Bortolin Laura T PNA-DNA oligomers and methods of use thereof
US7820389B2 (en) 2007-01-10 2010-10-26 Geneohm Sciences, Inc. Inhibition of mismatch hybridization by a universal competitor DNA
JP5588970B2 (ja) 2008-05-27 2014-09-10 ダコ・デンマーク・エー/エス ハイブリダイゼーション組成物及び方法
US9303287B2 (en) 2009-02-26 2016-04-05 Dako Denmark A/S Compositions and methods for RNA hybridization applications
WO2013046033A1 (en) 2011-09-30 2013-04-04 Dako Denmark A/S Hybridization compositions and methods using formamide
EP3252173A1 (en) 2011-10-21 2017-12-06 Dako Denmark A/S Hybridization compositions and methods
DK3109324T5 (en) * 2015-06-23 2019-02-11 Zytovision Gmbh PROCEDURE FOR THE DETECTION OF CHROMOSOMA DIFFERENCES
EP3599284A1 (en) 2018-07-27 2020-01-29 Bio-Id Diagnostic Inc. Simultaneous detection of multiple nucleic acid templates using modified primers
US12655470B2 (en) 2018-10-30 2026-06-16 Toray Industries, Inc. Inhibitor of non-specific binding of nucleic acid, hybridization reagent and nucleic acid hybridization method
TW202028222A (zh) 2018-11-14 2020-08-01 美商Ionis製藥公司 Foxp3表現之調節劑
ES3056904T3 (en) 2019-04-25 2026-02-25 Agilent Technologies Inc Hybridization compositions and methods for making and using compositions
WO2021207062A1 (en) * 2020-04-07 2021-10-14 Advanced Cell Diagnostics, Inc. Methods for detecting target nucleic acids by in situ hybridization and a kit thereof
CN113444776B (zh) * 2021-07-09 2025-02-18 苏州亿康医学检验有限公司 一种多重取代扩增技术制备重复序列的封闭试剂的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998024933A1 (en) * 1996-12-04 1998-06-11 Boston Probes, Inc. Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
WO2001038586A2 (en) * 1999-11-24 2001-05-31 Curagen Corporation Nucleic acids containing single nucleotide polymorphisms and methods of use thereof

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5447841A (en) * 1986-01-16 1995-09-05 The Regents Of The Univ. Of California Methods for chromosome-specific staining
US5225326A (en) * 1988-08-31 1993-07-06 Research Development Foundation One step in situ hybridization assay
DE68927059T3 (de) 1988-11-15 2001-05-10 Yale University, New Haven In-situ-unterdrückungs-hybridisierung und verwendungen
US5948634A (en) * 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
US5538869A (en) * 1990-12-13 1996-07-23 Board Of Regents, The University Of Texas System In-situ hybridization probes for identification and banding of specific human chromosomes and regions
US5714331A (en) * 1991-05-24 1998-02-03 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5641625A (en) * 1992-05-22 1997-06-24 Isis Pharmaceuticals, Inc. Cleaving double-stranded DNA with peptide nucleic acids
US5719262A (en) * 1993-11-22 1998-02-17 Buchardt, Deceased; Ole Peptide nucleic acids having amino acid side chains
US5539082A (en) * 1993-04-26 1996-07-23 Nielsen; Peter E. Peptide nucleic acids
US6228982B1 (en) * 1992-05-22 2001-05-08 Benget Norden Double-stranded peptide nucleic acids
DK51092D0 (da) * 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
US5766855A (en) * 1991-05-24 1998-06-16 Buchardt, Deceased; Ole Peptide nucleic acids having enhanced binding affinity and sequence specificity
GB9211979D0 (en) * 1992-06-05 1992-07-15 Buchard Ole Uses of nucleic acid analogues
US5527675A (en) * 1993-08-20 1996-06-18 Millipore Corporation Method for degradation and sequencing of polymers which sequentially eliminate terminal residues
DE4331012A1 (de) * 1993-09-13 1995-03-16 Bayer Ag Nukleinsäuren-bindende Oligomere mit N-Verzweigung für Therapie und Diagnostik
GB2284209A (en) * 1993-11-25 1995-05-31 Ole Buchardt Nucleic acid analogue-induced transcription of RNA from a double-stranded DNA template
EP0760008A1 (en) * 1994-05-19 1997-03-05 Dako A/S Pna probes for detection of neisseria gonorrhoeae and chlamydia trachomatis
US5705333A (en) 1994-08-05 1998-01-06 The Regents Of The University Of California Peptide-based nucleic acid mimics(PENAMS)
US5681702A (en) * 1994-08-30 1997-10-28 Chiron Corporation Reduction of nonspecific hybridization by using novel base-pairing schemes
US6280964B1 (en) * 1995-04-14 2001-08-28 The Regents Of The University Of California Binding sites for phosphotyrosine binding domains
US5690894A (en) * 1995-05-23 1997-11-25 The Regents Of The University Of California High density array fabrication and readout method for a fiber optic biosensor
US5814444A (en) * 1995-06-07 1998-09-29 University Of Washington Methods for making and using single-chromosome amplfication libraries
EP0854937B9 (en) 1995-10-06 2006-06-28 Perseptive Biosystems, Inc. Methods and kit for hybridization analysis using peptide nucleic acid probes
DE69637086T2 (de) 1995-10-12 2008-01-10 Lansdorp, Peter M., Vancouver Verfahren zum nachweis von mehrfachkopien einer wiederholungssequenz in einem nukleinsäuremolekül
US5888733A (en) * 1995-11-16 1999-03-30 Dako A/S In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
US5773649A (en) * 1996-06-10 1998-06-30 Centre De Recherche De L'hopital Sainte-Justine DNA markers to detect cancer cells expressing a mutator phenotype and method of diagnosis of cancer cells
US6107470A (en) * 1997-05-29 2000-08-22 Nielsen; Peter E. Histidine-containing peptide nucleic acids
US6962778B1 (en) * 1997-09-25 2005-11-08 Boston Probes, Inc. Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
US6485901B1 (en) 1997-10-27 2002-11-26 Boston Probes, Inc. Methods, kits and compositions pertaining to linear beacons
US6326479B1 (en) * 1998-01-27 2001-12-04 Boston Probes, Inc. Synthetic polymers and methods, kits or compositions for modulating the solubility of same
WO1999049293A2 (en) 1998-03-24 1999-09-30 Boston Probes, Inc. Methods, kits and compositions pertaining to detection complexes
US6238921B1 (en) * 1998-03-26 2001-05-29 Isis Pharmaceuticals, Inc. Antisense oligonucleotide modulation of human mdm2 expression
US6287772B1 (en) * 1998-04-29 2001-09-11 Boston Probes, Inc. Methods, kits and compositions for detecting and quantitating target sequences
EP1078098A1 (en) 1998-05-04 2001-02-28 Dako A/S Method and probes for the detection of chromosome aberrations
WO2000034521A1 (en) * 1998-12-08 2000-06-15 Boston Probes, Inc. Methods, kits and compositions for the identification of nucleic acids electrostatically bound to matrices
HUP0201512A3 (en) 1999-06-17 2010-01-28 Boehringer Ingelheim Ca Ltd New atpase assay
US6171860B1 (en) * 1999-11-05 2001-01-09 Isis Pharmaceuticals, Inc. Antisense inhibition of rank expression
US6492171B2 (en) * 2000-05-16 2002-12-10 Isis Pharmaceuticals, Inc. Antisense modulation of TERT expression
US6610499B1 (en) * 2000-08-31 2003-08-26 The Regents Of The University Of California Capillary array and related methods
US20030129626A1 (en) * 2001-09-24 2003-07-10 Nielsen Kirsten Vang Methods, kits and compositions pertaining to the suppression of detectable probe binding to randomly distributed repeat sequences in genomic nucleic acid

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998024933A1 (en) * 1996-12-04 1998-06-11 Boston Probes, Inc. Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
WO2001038586A2 (en) * 1999-11-24 2001-05-31 Curagen Corporation Nucleic acids containing single nucleotide polymorphisms and methods of use thereof

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006242618A (ja) * 2005-03-01 2006-09-14 Univ Of Tokyo 組織fish法によるテロメア量を指標とした癌の診断
JP2012040029A (ja) * 2006-08-08 2012-03-01 Arkray Inc 変異の検出方法およびそれに用いるキット
WO2017138500A1 (ja) * 2016-02-09 2017-08-17 公益財団法人がん研究会 希少造血器腫瘍の診断マーカー、検査方法、治療薬及びスクリーニング方法
JPWO2017138500A1 (ja) * 2016-02-09 2018-12-20 公益財団法人がん研究会 希少造血器腫瘍の診断マーカー、検査方法、治療薬及びスクリーニング方法
JP7082489B2 (ja) 2016-02-09 2022-06-08 公益財団法人がん研究会 希少造血器腫瘍の診断マーカー、検査方法、治療薬及びスクリーニング方法
US12630883B2 (en) 2016-02-09 2026-05-19 Japanese Foundation For Cancer Research Test method of dividing blastic plasmacytoid dendritic cell neoplasm (BPDCN) into subtypes
WO2018101375A1 (ja) * 2016-11-30 2018-06-07 国立大学法人秋田大学 ヒトゲノムdna検出方法
JPWO2018101375A1 (ja) * 2016-11-30 2019-10-24 国立大学法人秋田大学 ヒトゲノムdna検出方法

Also Published As

Publication number Publication date
US8754191B2 (en) 2014-06-17
US20140378326A1 (en) 2014-12-25
WO2003027328A2 (en) 2003-04-03
US11111525B2 (en) 2021-09-07
US20130150264A1 (en) 2013-06-13
US20180312912A1 (en) 2018-11-01
WO2003027328A3 (en) 2004-04-01
EP1432826A2 (en) 2004-06-30
US9951377B2 (en) 2018-04-24
US20110306520A1 (en) 2011-12-15
EP1432826B1 (en) 2012-12-12
US20030129626A1 (en) 2003-07-10

Similar Documents

Publication Publication Date Title
US11111525B2 (en) Methods, kits and compositions pertaining to the suppression of the detectable probe binding to randomly distributed repeat sequences genomic nucleic acid
US6656687B1 (en) Multiplex PNA-ISH assay
AU2002250262B9 (en) Methods, kits and compositions of combination oligomers
US5888733A (en) In situ hybridization to detect specific nucleic acid sequences in eucaryotic samples
EP0946750B1 (en) Methods, kits and compositions for suppressing the binding of detectable probes to non-target sequences in hybridization assays
US7642057B2 (en) Method and probes for the detection of chromosome aberrations
JP2009118853A (ja) 真核系サンプル中の特異的核酸配列を検出するためのinsituハイブリダイゼーション
EP1349958B1 (en) Probes, probe sets, methods and kits pertaining to the detection, identification and/or enumeration of bacteria
CN101495647B (zh) 用于微生物分析的肽核酸探针
US7981599B1 (en) Non-nucleic acid probes, probe sets, methods and kits pertaining to the detection of individual human chromosomes X, Y, 1, 2, 3, 4, 6, 7, 8, 9, 10, 11, 12, 16, 17, 18 and 20 as 13/21 as a pair
Poulsen et al. Situ Hybridization (FISH)
AU2007200335B2 (en) Methods, kits and compositions pertaining to combination oligomers and libraries for their preparation
HK1149592B (en) Peptide nucleic acid probes for analysis of microorganisms

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20050922

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20050922

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080828

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081117

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20081125

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20090302

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100330