JP2005522212A - ヘテロクリティックアナログおよび関係する方法 - Google Patents

ヘテロクリティックアナログおよび関係する方法 Download PDF

Info

Publication number
JP2005522212A
JP2005522212A JP2003584081A JP2003584081A JP2005522212A JP 2005522212 A JP2005522212 A JP 2005522212A JP 2003584081 A JP2003584081 A JP 2003584081A JP 2003584081 A JP2003584081 A JP 2003584081A JP 2005522212 A JP2005522212 A JP 2005522212A
Authority
JP
Japan
Prior art keywords
epitope
analog
peptide
seq
analogs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003584081A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005522212A5 (https=
Inventor
イシオカ グレン
ファイクス ジョン
タングリ シャブナム
セッテ アレッサンドロ
Original Assignee
エピミューン インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/116,118 external-priority patent/US8741576B2/en
Application filed by エピミューン インコーポレイテッド filed Critical エピミューン インコーポレイテッド
Publication of JP2005522212A publication Critical patent/JP2005522212A/ja
Publication of JP2005522212A5 publication Critical patent/JP2005522212A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70539MHC-molecules, e.g. HLA-molecules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2003584081A 2002-04-05 2003-04-07 ヘテロクリティックアナログおよび関係する方法 Pending JP2005522212A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/116,118 US8741576B2 (en) 1999-11-18 2002-04-05 Heteroclitic analogs and related methods
US41347102P 2002-09-26 2002-09-26
PCT/US2003/010571 WO2003087126A2 (en) 2002-04-05 2003-04-07 Heteroclitic analogs and related methods

Publications (2)

Publication Number Publication Date
JP2005522212A true JP2005522212A (ja) 2005-07-28
JP2005522212A5 JP2005522212A5 (https=) 2006-06-01

Family

ID=29253934

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003584081A Pending JP2005522212A (ja) 2002-04-05 2003-04-07 ヘテロクリティックアナログおよび関係する方法

Country Status (6)

Country Link
US (1) US20060018915A1 (https=)
EP (1) EP1495322A4 (https=)
JP (1) JP2005522212A (https=)
AU (1) AU2003221831A1 (https=)
CA (1) CA2481462A1 (https=)
WO (1) WO2003087126A2 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0720118D0 (en) * 2007-10-15 2007-11-28 Achour Adnane Modified mhc class 1 binding peptides
BRPI0817682A2 (pt) 2007-10-16 2015-04-07 Peptimmune Inc Métodos para projetar e preparar vacinas compreendendo composições de polímero de sequência direcionada via a expansão direta de epítopos
US8711176B2 (en) 2008-05-22 2014-04-29 Yahoo! Inc. Virtual billboards
US20090289955A1 (en) * 2008-05-22 2009-11-26 Yahoo! Inc. Reality overlay device
EP2391635B1 (en) 2009-01-28 2017-04-26 Epimmune Inc. Pan-dr binding polypeptides and uses thereof
PT2413956T (pt) * 2009-04-02 2016-12-30 Vaxon Biotech Identificação, optimização e utilização de epitopos crípticos hla-a24 para imunoterapia
WO2011083493A1 (en) * 2010-01-08 2011-07-14 National Institute Of Immunology Human chorionic gonadotropin (hcg) based vaccine for prevention and treatment of cancer
WO2012023033A2 (en) 2010-08-18 2012-02-23 Purdue Pharma L.P. Improved peptide immunogens
CN108503689B (zh) * 2017-07-10 2019-12-31 昆明医科大学第一附属医院 一种抗血小板聚集的多肽km6
CN116710115A (zh) 2020-11-20 2023-09-05 思维疗法股份有限公司 用于优化的肽疫苗的组合物和方法
US11421015B2 (en) 2020-12-07 2022-08-23 Think Therapeutics, Inc. Method of compact peptide vaccines using residue optimization
US11058751B1 (en) 2020-11-20 2021-07-13 Think Therapeutics, Inc. Compositions for optimized RAS peptide vaccines
US11464842B1 (en) 2021-04-28 2022-10-11 Think Therapeutics, Inc. Compositions and method for optimized peptide vaccines using residue optimization

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6419931B1 (en) * 1991-08-26 2002-07-16 Epimmune Inc. Compositions and methods for eliciting CTL immunity
JP2001504799A (ja) * 1996-03-11 2001-04-10 エピミューン インコーポレイテッド Hla分子への結合アフィニティーが増加したペプチド
EP1064022A4 (en) * 1998-03-13 2004-09-29 Epimmune Inc HLA BINDING PROTEINS AND THEIR USE
US6632435B1 (en) * 1999-10-20 2003-10-14 City Of Hope CTL epitope analogs
AU1661201A (en) * 1999-11-18 2001-05-30 Epimmune, Inc. Heteroclitic analogs and related methods
WO2002020616A1 (en) * 2000-09-01 2002-03-14 Epimmune Inc. Hla-a2.1 binding peptides and their uses

Also Published As

Publication number Publication date
EP1495322A4 (en) 2006-09-06
WO2003087126A3 (en) 2004-10-28
US20060018915A1 (en) 2006-01-26
AU2003221831A1 (en) 2003-10-27
EP1495322A2 (en) 2005-01-12
CA2481462A1 (en) 2003-10-23
WO2003087126A2 (en) 2003-10-23

Similar Documents

Publication Publication Date Title
JP4776131B2 (ja) ヘテロクリティックアナログおよび関連方法
JP5156882B2 (ja) Hla−a2腫瘍関連抗原ペプチドおよび組成物
US20060094649A1 (en) Hla-a1,-a2,-a3,-a24,-b7, and-b44 tumor associated antigen peptides and compositions
US20040037843A1 (en) Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions
CA2393738A1 (en) Inducing cellular immune responses to her2/neu using peptide and nucleic acid compositions
US20070020327A1 (en) Inducing cellular immune responses to prostate cancer antigens using peptide and nucleic acid compositions
EP1242049A1 (en) Hla class i a2 tumor associated antigen peptides and vaccine compositions
US20040146519A1 (en) Inducing cellular immune responses to carcinoembryonic antigen using peptide and nucleic acid compositions
JP2005522212A (ja) ヘテロクリティックアナログおよび関係する方法
US20030224036A1 (en) Hla class I a2 tumor associated antigen peptides and vaccine compositions
CA2393339A1 (en) Inducing cellular immune responses to mage2/3 using peptide and nucleic acid compositions

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060407

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060407

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090501

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20090803

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20090810

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20091027