JP2005518799A5 - - Google Patents

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Publication number
JP2005518799A5
JP2005518799A5 JP2003571511A JP2003571511A JP2005518799A5 JP 2005518799 A5 JP2005518799 A5 JP 2005518799A5 JP 2003571511 A JP2003571511 A JP 2003571511A JP 2003571511 A JP2003571511 A JP 2003571511A JP 2005518799 A5 JP2005518799 A5 JP 2005518799A5
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JP
Japan
Prior art keywords
dna
duplex
binding substance
molecule
stranded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2003571511A
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English (en)
Japanese (ja)
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JP2005518799A (ja
JP4455061B2 (ja
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Priority claimed from PCT/US2003/006500 external-priority patent/WO2003072832A1/en
Publication of JP2005518799A publication Critical patent/JP2005518799A/ja
Publication of JP2005518799A5 publication Critical patent/JP2005518799A5/ja
Application granted granted Critical
Publication of JP4455061B2 publication Critical patent/JP4455061B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003571511A 2002-02-28 2003-02-28 核酸集団のエラー減少方法 Expired - Fee Related JP4455061B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36056302P 2002-02-28 2002-02-28
PCT/US2003/006500 WO2003072832A1 (en) 2002-02-28 2003-02-28 Method of error reduction in nucleic acid populations

Publications (3)

Publication Number Publication Date
JP2005518799A JP2005518799A (ja) 2005-06-30
JP2005518799A5 true JP2005518799A5 (enExample) 2006-04-20
JP4455061B2 JP4455061B2 (ja) 2010-04-21

Family

ID=27766234

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003571511A Expired - Fee Related JP4455061B2 (ja) 2002-02-28 2003-02-28 核酸集団のエラー減少方法

Country Status (12)

Country Link
US (2) US7303872B2 (enExample)
EP (1) EP1483409B1 (enExample)
JP (1) JP4455061B2 (enExample)
KR (1) KR101026816B1 (enExample)
AT (1) ATE428805T1 (enExample)
AU (1) AU2003213696B2 (enExample)
CA (1) CA2477519C (enExample)
DE (1) DE60327183D1 (enExample)
IL (2) IL163788A0 (enExample)
IS (1) IS7430A (enExample)
MX (1) MXPA04008373A (enExample)
WO (1) WO2003072832A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002095073A1 (en) 2001-05-18 2002-11-28 Wisconsin Alumni Research Foundation Method for the synthesis of dna sequences
WO2003072832A1 (en) * 2002-02-28 2003-09-04 Wisconsin Alumni Research Foundation Method of error reduction in nucleic acid populations
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides
US8133670B2 (en) 2003-06-13 2012-03-13 Cold Spring Harbor Laboratory Method for making populations of defined nucleic acid molecules
SG110153A1 (en) * 2003-09-22 2005-04-28 Agency Science Tech & Res Device and method of detecting mutations and polymorphisms in dna
WO2005089110A2 (en) * 2004-02-27 2005-09-29 President And Fellows Of Harvard College Polynucleotide synthesis
EP1574570A1 (en) * 2004-03-12 2005-09-14 Universität Regensburg Process for reducing the number of mismatches in double stranded polynucleotides
AU2005254972B2 (en) * 2004-06-09 2010-11-04 Wisconsin Alumni Research Foundation Rapid production of oligonucleotides
JP2008517586A (ja) * 2004-08-27 2008-05-29 ウイスコンシン アラムニ リサーチ ファンデーション 核酸集団中のエラーを減少させる方法
US20070122817A1 (en) * 2005-02-28 2007-05-31 George Church Methods for assembly of high fidelity synthetic polynucleotides
CA2584984A1 (en) * 2004-10-18 2006-04-27 Codon Devices, Inc. Methods for assembly of high fidelity synthetic polynucleotides
US7722824B2 (en) 2005-08-02 2010-05-25 Wisconsin Alumni Research Foundation Synthesis of arrays of oligonucleotides and other chain molecules
US20070196834A1 (en) * 2005-09-09 2007-08-23 Francesco Cerrina Method and system for the generation of large double stranded DNA fragments
US20070231805A1 (en) * 2006-03-31 2007-10-04 Baynes Brian M Nucleic acid assembly optimization using clamped mismatch binding proteins
WO2007136834A2 (en) * 2006-05-19 2007-11-29 Codon Devices, Inc. Combined extension and ligation for nucleic acid assembly
US8053191B2 (en) 2006-08-31 2011-11-08 Westend Asset Clearinghouse Company, Llc Iterative nucleic acid assembly using activation of vector-encoded traits
US10207240B2 (en) 2009-11-03 2019-02-19 Gen9, Inc. Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly
US9216414B2 (en) 2009-11-25 2015-12-22 Gen9, Inc. Microfluidic devices and methods for gene synthesis
WO2011066186A1 (en) 2009-11-25 2011-06-03 Gen9, Inc. Methods and apparatuses for chip-based dna error reduction
US9217144B2 (en) 2010-01-07 2015-12-22 Gen9, Inc. Assembly of high fidelity polynucleotides
WO2012078312A2 (en) 2010-11-12 2012-06-14 Gen9, Inc. Methods and devices for nucleic acids synthesis
US10457935B2 (en) 2010-11-12 2019-10-29 Gen9, Inc. Protein arrays and methods of using and making the same
EP2748318B1 (en) 2011-08-26 2015-11-04 Gen9, Inc. Compositions and methods for high fidelity assembly of nucleic acids
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
CN104603286B (zh) 2012-04-24 2020-07-31 Gen9股份有限公司 在体外克隆中分选核酸和多重制备物的方法
CN104685116A (zh) 2012-06-25 2015-06-03 Gen9股份有限公司 用于核酸组装和高通量测序的方法
WO2014058890A1 (en) * 2012-10-08 2014-04-17 Spiral Genetics Inc. Methods and systems for identifying, from read symbol sequences, variations with respect to a reference symbol sequence

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5376526A (en) * 1992-05-06 1994-12-27 The Board Of Trustees Of The Leland Stanford Junior University Genomic mismatch scanning
US6120992A (en) * 1993-11-04 2000-09-19 Valigene Corporation Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, and allele identification in a diseased human
US6027877A (en) 1993-11-04 2000-02-22 Gene Check, Inc. Use of immobilized mismatch binding protein for detection of mutations and polymorphisms, purification of amplified DNA samples and allele identification
WO1999006591A1 (en) 1997-07-31 1999-02-11 The Institute Of Physical And Chemical Research Methods for detecting mutation in base sequence
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
US6297010B1 (en) * 1998-01-30 2001-10-02 Genzyme Corporation Method for detecting and identifying mutations
GB9808145D0 (en) * 1998-04-17 1998-06-17 Zeneca Ltd Assay
US6287825B1 (en) * 1998-09-18 2001-09-11 Molecular Staging Inc. Methods for reducing the complexity of DNA sequences
DE50015858D1 (de) 1999-02-19 2010-03-18 Febit Holding Gmbh Verfahren zur Herstellung von Polymeren
US20030186226A1 (en) 1999-03-08 2003-10-02 Brennan Thomas M. Methods and compositions for economically synthesizing and assembling long DNA sequences
WO2002095073A1 (en) * 2001-05-18 2002-11-28 Wisconsin Alumni Research Foundation Method for the synthesis of dna sequences
US6673552B2 (en) * 2002-01-14 2004-01-06 Diversa Corporation Methods for purifying annealed double-stranded oligonucleotides lacking base pair mismatches or nucleotide gaps
WO2003072832A1 (en) * 2002-02-28 2003-09-04 Wisconsin Alumni Research Foundation Method of error reduction in nucleic acid populations
US7563600B2 (en) 2002-09-12 2009-07-21 Combimatrix Corporation Microarray synthesis and assembly of gene-length polynucleotides

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