JP2005515200A5 - - Google Patents
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- Publication number
- JP2005515200A5 JP2005515200A5 JP2003548835A JP2003548835A JP2005515200A5 JP 2005515200 A5 JP2005515200 A5 JP 2005515200A5 JP 2003548835 A JP2003548835 A JP 2003548835A JP 2003548835 A JP2003548835 A JP 2003548835A JP 2005515200 A5 JP2005515200 A5 JP 2005515200A5
- Authority
- JP
- Japan
- Prior art keywords
- triprolidine
- active ingredient
- sleep
- hydrate
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- CBEQULMOCCWAQT-WOJGMQOQSA-N triprolidine Chemical compound C1=CC(C)=CC=C1C(\C=1N=CC=CC=1)=C/CN1CCCC1 CBEQULMOCCWAQT-WOJGMQOQSA-N 0.000 claims 28
- 229960001128 triprolidine Drugs 0.000 claims 27
- 239000004480 active ingredient Substances 0.000 claims 19
- 239000000203 mixture Substances 0.000 claims 18
- 150000003839 salts Chemical class 0.000 claims 10
- 238000009472 formulation Methods 0.000 claims 8
- 231100000252 nontoxic Toxicity 0.000 claims 8
- 230000003000 nontoxic effect Effects 0.000 claims 8
- 239000003085 diluting agent Substances 0.000 claims 5
- 239000007884 disintegrant Substances 0.000 claims 5
- 238000004519 manufacturing process Methods 0.000 claims 4
- 239000000825 pharmaceutical preparation Substances 0.000 claims 4
- 238000002360 preparation method Methods 0.000 claims 4
- 239000002671 adjuvant Substances 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 229920001477 hydrophilic polymer Polymers 0.000 claims 2
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical group [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims 2
- 239000000843 powder Substances 0.000 claims 2
- 208000019116 sleep disease Diseases 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 230000002618 waking effect Effects 0.000 claims 2
- WYUYEJNGHIOFOC-VVTVMFAVSA-N 2-[(z)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridine;hydrochloride Chemical compound Cl.C1=CC(C)=CC=C1C(\C=1N=CC=CC=1)=C\CN1CCCC1 WYUYEJNGHIOFOC-VVTVMFAVSA-N 0.000 claims 1
- 229920002785 Croscarmellose sodium Polymers 0.000 claims 1
- 230000002745 absorbent Effects 0.000 claims 1
- 239000002250 absorbent Substances 0.000 claims 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical group [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims 1
- 239000012752 auxiliary agent Substances 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 229960001681 croscarmellose sodium Drugs 0.000 claims 1
- 235000010947 crosslinked sodium carboxy methyl cellulose Nutrition 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000839 emulsion Substances 0.000 claims 1
- 238000005469 granulation Methods 0.000 claims 1
- 230000003179 granulation Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- 235000019359 magnesium stearate Nutrition 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 230000003860 sleep quality Effects 0.000 claims 1
- 230000004622 sleep time Effects 0.000 claims 1
- 239000000829 suppository Substances 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 239000006188 syrup Substances 0.000 claims 1
- 235000020357 syrup Nutrition 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 229960001593 triprolidine hydrochloride Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0128674.9A GB0128674D0 (en) | 2001-11-30 | 2001-11-30 | Treatment of sleep disorders and the like |
| US10/305,354 US20030134878A1 (en) | 2001-11-30 | 2002-11-27 | Use of a compound in providing refreshedness on waking and a method for the treatment of drowsiness therewith |
| PCT/GB2002/005427 WO2003047580A1 (en) | 2001-11-30 | 2002-12-02 | Use of a compound in the treatment of sleep disorders and the like, in providing refreshedness on waking and a method for the treatment of grogginess therewith |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005515200A JP2005515200A (ja) | 2005-05-26 |
| JP2005515200A5 true JP2005515200A5 (enExample) | 2006-01-05 |
Family
ID=9926729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003548835A Pending JP2005515200A (ja) | 2001-11-30 | 2002-12-02 | 睡眠異常症（ｓｌｅｅｐｄｉｓｏｒｄｅｒ）等の治療、目覚め時の爽快感の付与を目的とした一化合物の使用及び前記化合物を用いた足元のふらつき（ｇｒｏｇｇｉｎｅｓｓ）の治療法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20030134878A1 (enExample) |
| EP (1) | EP1455786A1 (enExample) |
| JP (1) | JP2005515200A (enExample) |
| CN (1) | CN1617723A (enExample) |
| AU (2) | AU2002350897B2 (enExample) |
| CA (1) | CA2468044A1 (enExample) |
| GB (3) | GB0128674D0 (enExample) |
| IL (1) | IL162146A0 (enExample) |
| NO (1) | NO20042389L (enExample) |
| PL (1) | PL370258A1 (enExample) |
| RU (1) | RU2320340C2 (enExample) |
| WO (1) | WO2003047580A1 (enExample) |
| ZA (1) | ZA200404172B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0312425D0 (en) * | 2003-05-30 | 2003-07-09 | Boots Co Plc | Use of a compound in the treatment of sleep disorders and the like,in providing refreshedness on waking and a method for the treatment of grogginess therewith |
| DE10332486A1 (de) * | 2003-07-16 | 2005-02-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Ambroxol für die Behandlung akuter Schmerzen |
| BRPI0414112A (pt) * | 2003-09-03 | 2006-10-31 | Novartis Ag | uso de oxcarbazepina para o tratamento de dor neuropática diabética e a melhora do sono |
| CN101039664A (zh) * | 2004-10-14 | 2007-09-19 | 大金工业株式会社 | 气氛改变方法、用于该气氛改变方法的喷雾剂与喷雾装置 |
| JP2006137748A (ja) * | 2004-10-14 | 2006-06-01 | Daikin Ind Ltd | 雰囲気改変方法、並びに、それに用いられる噴霧剤及び噴霧装置 |
| WO2007070504A2 (en) * | 2005-12-13 | 2007-06-21 | Morton Grove Pharmaceuticals, Inc. | Stable and palatable oral liquid sumatriptan compositions |
| US20070299127A1 (en) * | 2006-06-23 | 2007-12-27 | The Procter & Gamble Company | Compositions and kits comprising a melatonin component and an omega-3-fatty acid component |
| WO2008073961A2 (en) * | 2006-12-12 | 2008-06-19 | Emory University | Compounds and methods for modulating the silencing of a polynucleotide of interest |
| CN101868252A (zh) * | 2007-11-21 | 2010-10-20 | 宝洁公司 | 可用于治疗咳嗽的制剂、方法和试剂盒 |
| WO2011035120A2 (en) * | 2009-09-17 | 2011-03-24 | Gk Ventures, L.L.C. | Therapeutic composition to treat lesions caused by herpes simplex virus |
| IL254641B2 (en) | 2015-03-26 | 2024-01-01 | Jacqueline M Iversen | Methods and preparations including naproxen and fexofenamide for relieving symptoms of dizziness associated with alcohol consumption |
| GR1010679B (el) * | 2023-02-03 | 2024-04-26 | Ιουλια Κλεωνος Τσετη | Φαρμακευτικη συνθεση παρακεταμολης υπο μορφη τροχισκων ή παστιλιων με βελτιωτικο γευσης συμβατο με την παρακεταμολη |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4269835A (en) * | 1979-12-13 | 1981-05-26 | Whittle Barry J | Nasal composition for relieving nasal distress |
| US4639459A (en) * | 1983-02-01 | 1987-01-27 | Burroughs Wellcome Co. | Use of trifluoromethyl compounds |
| US4642231A (en) * | 1983-07-20 | 1987-02-10 | Warner-Lambert Company | Magnesium trisilicate suitable for preparation of medicament adsorbates of antihistamines |
| US5025019A (en) * | 1984-04-09 | 1991-06-18 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
| US6077822A (en) * | 1993-09-14 | 2000-06-20 | Dumex-Alpharma A/S | Drug salts |
| US6596298B2 (en) * | 1998-09-25 | 2003-07-22 | Warner-Lambert Company | Fast dissolving orally comsumable films |
| PT1202722E (pt) * | 1999-08-13 | 2005-11-30 | L & L Technologies Llc | Usos para o tratamento ou prevencao de disturbios do sono usando doses muito baixas de ciclobenzaprina |
| US20030190360A1 (en) * | 2001-03-13 | 2003-10-09 | Baichwal Anand R. | Chronotherapeutic dosage forms containing glucocorticosteroid and methods of treatment |
| US6827946B2 (en) * | 2001-12-05 | 2004-12-07 | Collegium Pharmaceutical, Inc. | Compositions containing both sedative and non-sedative antihistamines |
-
2001
- 2001-11-30 GB GBGB0128674.9A patent/GB0128674D0/en not_active Ceased
-
2002
- 2002-11-27 US US10/305,354 patent/US20030134878A1/en not_active Abandoned
- 2002-11-28 GB GBGB0227708.5A patent/GB0227708D0/en not_active Ceased
- 2002-12-02 CN CNA028276256A patent/CN1617723A/zh active Pending
- 2002-12-02 WO PCT/GB2002/005427 patent/WO2003047580A1/en not_active Ceased
- 2002-12-02 IL IL16214602A patent/IL162146A0/xx unknown
- 2002-12-02 CA CA002468044A patent/CA2468044A1/en not_active Abandoned
- 2002-12-02 EP EP02785610A patent/EP1455786A1/en not_active Withdrawn
- 2002-12-02 RU RU2004119832/15A patent/RU2320340C2/ru active
- 2002-12-02 GB GB0228045A patent/GB2383537B/en not_active Expired - Fee Related
- 2002-12-02 AU AU2002350897A patent/AU2002350897B2/en not_active Ceased
- 2002-12-02 JP JP2003548835A patent/JP2005515200A/ja active Pending
- 2002-12-02 AU AU2002313364A patent/AU2002313364B2/en not_active Ceased
- 2002-12-02 US US10/496,643 patent/US20050282869A1/en not_active Abandoned
- 2002-12-02 PL PL02370258A patent/PL370258A1/xx not_active Application Discontinuation
-
2003
- 2003-05-30 US US10/448,455 patent/US20040029927A1/en not_active Abandoned
-
2004
- 2004-05-27 ZA ZA200404172A patent/ZA200404172B/xx unknown
- 2004-06-08 NO NO20042389A patent/NO20042389L/no not_active Application Discontinuation
-
2005
- 2005-12-16 US US11/303,019 patent/US20070015800A1/en not_active Abandoned
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