JP2005515191A5 - - Google Patents
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- Publication number
- JP2005515191A5 JP2005515191A5 JP2003546869A JP2003546869A JP2005515191A5 JP 2005515191 A5 JP2005515191 A5 JP 2005515191A5 JP 2003546869 A JP2003546869 A JP 2003546869A JP 2003546869 A JP2003546869 A JP 2003546869A JP 2005515191 A5 JP2005515191 A5 JP 2005515191A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- composition according
- ions
- mmol
- rubidium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 29
- 206010052428 Wound Diseases 0.000 claims description 9
- 208000027418 Wounds and injury Diseases 0.000 claims description 6
- 230000035876 healing Effects 0.000 claims description 5
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 4
- 229910001424 calcium ion Inorganic materials 0.000 claims description 4
- 229910001419 rubidium ion Inorganic materials 0.000 claims description 4
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 2
- IGLNJRXAVVLDKE-UHFFFAOYSA-N rubidium atom Chemical compound [Rb] IGLNJRXAVVLDKE-UHFFFAOYSA-N 0.000 claims description 2
- 239000011701 zinc Substances 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims 3
- PTFCDOFLOPIGGS-UHFFFAOYSA-N Zinc dication Chemical compound [Zn+2] PTFCDOFLOPIGGS-UHFFFAOYSA-N 0.000 claims 3
- 230000001684 chronic effect Effects 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 229910001414 potassium ion Inorganic materials 0.000 claims 3
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 claims 2
- 108090000862 Ion Channels Proteins 0.000 claims 2
- 102000004310 Ion Channels Human genes 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000001110 calcium chloride Substances 0.000 claims 2
- 229910001628 calcium chloride Inorganic materials 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 230000001737 promoting effect Effects 0.000 claims 2
- FGDZQCVHDSGLHJ-UHFFFAOYSA-M rubidium chloride Chemical compound [Cl-].[Rb+] FGDZQCVHDSGLHJ-UHFFFAOYSA-M 0.000 claims 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 claims 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 102000000424 Matrix Metalloproteinase 2 Human genes 0.000 claims 1
- 108010016165 Matrix Metalloproteinase 2 Proteins 0.000 claims 1
- 102000001776 Matrix metalloproteinase-9 Human genes 0.000 claims 1
- 108010015302 Matrix metalloproteinase-9 Proteins 0.000 claims 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 230000005465 channeling Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000012153 distilled water Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 229910052760 oxygen Inorganic materials 0.000 claims 1
- 239000001301 oxygen Substances 0.000 claims 1
- 239000001508 potassium citrate Substances 0.000 claims 1
- 229960002635 potassium citrate Drugs 0.000 claims 1
- QEEAPRPFLLJWCF-UHFFFAOYSA-K potassium citrate (anhydrous) Chemical compound [K+].[K+].[K+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O QEEAPRPFLLJWCF-UHFFFAOYSA-K 0.000 claims 1
- 235000011082 potassium citrates Nutrition 0.000 claims 1
- 229910052701 rubidium Inorganic materials 0.000 claims 1
- 229940102127 rubidium chloride Drugs 0.000 claims 1
- -1 rubidium chloride zinc chloride Chemical compound 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 239000011592 zinc chloride Substances 0.000 claims 1
- 235000005074 zinc chloride Nutrition 0.000 claims 1
- 238000003556 assay Methods 0.000 description 2
- 230000029663 wound healing Effects 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 230000024203 complement activation Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000005414 inactive ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33433701P | 2001-11-29 | 2001-11-29 | |
| PCT/US2002/038175 WO2003045366A1 (en) | 2001-11-29 | 2002-11-27 | Treatment of wounds and compositions employed |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005515191A JP2005515191A (ja) | 2005-05-26 |
| JP2005515191A5 true JP2005515191A5 (https=) | 2006-01-26 |
Family
ID=23306754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003546869A Pending JP2005515191A (ja) | 2001-11-29 | 2002-11-27 | 創傷の治療及び使用する組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (5) | US20030133991A1 (https=) |
| EP (1) | EP1461024A4 (https=) |
| JP (1) | JP2005515191A (https=) |
| AU (1) | AU2002359529B2 (https=) |
| CA (1) | CA2468390A1 (https=) |
| MX (1) | MXPA04005219A (https=) |
| NZ (1) | NZ533252A (https=) |
| WO (1) | WO2003045366A1 (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2486704A1 (en) * | 2002-05-24 | 2003-12-04 | Greystone Medical Group, Inc. | Anti-cancer formulation |
| CA2511440A1 (en) * | 2002-12-23 | 2004-07-15 | Greystone Medical Group, Inc. | Reduction of reactive oxygen species in chronic wound management |
| EP1660012A4 (en) * | 2003-08-25 | 2008-04-30 | Greystone Medical Group Inc | CELLULAR DEPOLARISATION AND REGULATION OF MATRIX METALLOPROTEINASES |
| AU2005258225A1 (en) * | 2004-06-22 | 2006-01-05 | Greystone Medical Group, Inc. | Methods for treatment of wounds using time release compositions |
| WO2007075853A2 (en) * | 2005-12-20 | 2007-07-05 | Swiss-American Products, Inc. | Protease compositions for the treatment of damaged tissue |
| US8795730B2 (en) * | 2006-01-31 | 2014-08-05 | David John Vachon | Compositions and methods for promoting the healing of tissue of multicellular organisms |
| KR101324578B1 (ko) | 2006-02-03 | 2013-11-01 | 제이알 켐, 엘엘씨 | 구리 및 아연 조성물을 사용하는 노화 방지 치료법 |
| US7687650B2 (en) | 2006-02-03 | 2010-03-30 | Jr Chem, Llc | Chemical compositions and methods of making them |
| US7897800B2 (en) * | 2006-02-03 | 2011-03-01 | Jr Chem, Llc | Chemical compositions and methods of making them |
| WO2007143586A2 (en) * | 2006-06-01 | 2007-12-13 | Pharmaionx, Inc. | Composition for wound care and method of using same |
| US7867522B2 (en) | 2006-09-28 | 2011-01-11 | Jr Chem, Llc | Method of wound/burn healing using copper-zinc compositions |
| WO2008146224A2 (en) | 2007-05-25 | 2008-12-04 | Compex Medical S.A. | Wound healing electrode set |
| ITBS20070178A1 (it) * | 2007-11-15 | 2009-05-16 | Paoli Ambrosi Gianfranco De | Composizione per uso farmaceutico e/o cosmetico e/o in forma di dispositivo medico per favorire processi di cicatrizzazione, per il trattamento di cicatrici ipertrofiche e per migliorare le proprieta' biomeccaniche della cute |
| CN101977599A (zh) * | 2007-12-11 | 2011-02-16 | 斯蒂芬·H·门罗 | 用于处理细胞环境和离子通道的缓冲水溶液的组合物及其使用方法 |
| US8273791B2 (en) | 2008-01-04 | 2012-09-25 | Jr Chem, Llc | Compositions, kits and regimens for the treatment of skin, especially décolletage |
| CA2750636C (en) | 2009-01-23 | 2017-07-25 | Jr Chem, Llc | Rosacea treatments and kits for performing them |
| US20110008271A1 (en) * | 2009-07-13 | 2011-01-13 | Jr Chem, Llc | Rosacea treatments using polymetal complexes |
| US8952057B2 (en) | 2011-01-11 | 2015-02-10 | Jr Chem, Llc | Compositions for anorectal use and methods for treating anorectal disorders |
| EP2671081A2 (en) | 2011-01-31 | 2013-12-11 | Systagenix Wound Management IP Co. BV. | Wound prognosis |
| GB201116523D0 (en) * | 2011-09-23 | 2011-11-09 | Systagenix Wound Man Ip Co Bv | Wound prognosis |
| US9351995B1 (en) | 2011-04-29 | 2016-05-31 | Red Oax Holdings, LLC | Compositions and methods of enhancing wound healing |
| EP2734243A1 (en) * | 2011-07-20 | 2014-05-28 | 3M Innovative Properties Company | Dressing with ion-carrying composition |
| JP6133858B2 (ja) * | 2011-07-28 | 2017-05-24 | スリーエム イノベイティブ プロパティズ カンパニー | 創傷治癒組成物及び使用方法 |
| US9962364B2 (en) | 2012-12-26 | 2018-05-08 | A-Z Ltd. | Wound healing accelerator |
| JP6694431B2 (ja) * | 2015-06-12 | 2020-05-13 | Ｊｆｅミネラル株式会社 | 皮膚創傷または皮膚荒れ治療剤 |
| WO2016199905A1 (ja) * | 2015-06-12 | 2016-12-15 | Ｊｆｅミネラル株式会社 | 皮膚創傷または皮膚荒れ治療剤 |
| CN110035762B (zh) * | 2016-12-09 | 2021-11-23 | 杰富意矿物股份有限公司 | 锌离子缓释性优异的无机组合物及其制造方法 |
| RU2636523C1 (ru) * | 2017-02-09 | 2017-11-23 | федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный медицинский университет имени Н.Н. Бурденко" Министерства здравоохранения Российской Федерации (ФГБОУ ВО ВГМУ им. Н.Н. Бурденко Минздрава России) | Лекарственное средство для ускорения заживления ран, содержащее хлорид рубидия в виде порошка |
| CN116631510B (zh) * | 2022-10-28 | 2024-01-12 | 中国人民解放军军事科学院军事医学研究院 | 一种用于鉴别诊断克罗恩病和溃疡性结肠炎的装置 |
| WO2024196897A1 (en) * | 2023-03-22 | 2024-09-26 | Courtland Imel | Novel methods for increasing healing speed of human and animal wounds |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4600711A (en) * | 1982-08-18 | 1986-07-15 | The University Of Kentucky Research Foundation | Composition for topical and infusion treatment of wounds and burns |
| DE3416777C2 (de) * | 1984-05-07 | 1986-11-20 | Gödecke AG, 1000 Berlin | Pharmazeutische topische Zubereitungen |
| WO1994011010A2 (en) * | 1992-11-06 | 1994-05-26 | H.E. Stanley Pharmaceuticals, Inc. | Compositions of oak bark extract, related synthetic compositions, and method of using same |
| AUPN104895A0 (en) * | 1995-02-10 | 1995-03-09 | Lai, John | Methods of and preparations for the treatment of ailments and disorders |
| GB9905663D0 (en) * | 1999-03-12 | 1999-05-05 | Bristol Myers Squibb Co | Iodine preparation composition |
| AU2001257397B2 (en) * | 2000-04-28 | 2005-08-04 | Biolife, L.L.C | Hemostatic agent, method and carrier for applying a blood clotting agent |
| US20020141964A1 (en) * | 2001-01-19 | 2002-10-03 | Patterson James A. | Composition for arresting the flow of blood and method |
| US6600057B2 (en) * | 2000-12-29 | 2003-07-29 | Kimberly-Clark Worldwide, Inc. | Matrix metalloproteinase inhibitors |
-
2002
- 2002-11-27 AU AU2002359529A patent/AU2002359529B2/en not_active Ceased
- 2002-11-27 US US10/305,713 patent/US20030133991A1/en not_active Abandoned
- 2002-11-27 JP JP2003546869A patent/JP2005515191A/ja active Pending
- 2002-11-27 EP EP02794072A patent/EP1461024A4/en not_active Withdrawn
- 2002-11-27 NZ NZ533252A patent/NZ533252A/xx not_active IP Right Cessation
- 2002-11-27 MX MXPA04005219A patent/MXPA04005219A/es unknown
- 2002-11-27 CA CA002468390A patent/CA2468390A1/en not_active Abandoned
- 2002-11-27 WO PCT/US2002/038175 patent/WO2003045366A1/en not_active Ceased
-
2005
- 2005-03-15 US US11/081,119 patent/US20060029682A1/en not_active Abandoned
-
2006
- 2006-09-20 US US11/523,869 patent/US20070009611A1/en not_active Abandoned
-
2007
- 2007-07-17 US US11/779,026 patent/US20070298121A1/en not_active Abandoned
-
2009
- 2009-09-23 US US12/565,244 patent/US20100196507A1/en not_active Abandoned
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