JP2005514361A5 - - Google Patents
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- Publication number
- JP2005514361A5 JP2005514361A5 JP2003545619A JP2003545619A JP2005514361A5 JP 2005514361 A5 JP2005514361 A5 JP 2005514361A5 JP 2003545619 A JP2003545619 A JP 2003545619A JP 2003545619 A JP2003545619 A JP 2003545619A JP 2005514361 A5 JP2005514361 A5 JP 2005514361A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- group
- aryl
- halogen
- here
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000000217 alkyl group Chemical group 0.000 claims 25
- 150000001875 compounds Chemical class 0.000 claims 22
- 125000001424 substituent group Chemical group 0.000 claims 22
- 125000003118 aryl group Chemical group 0.000 claims 21
- 229910052736 halogen Inorganic materials 0.000 claims 17
- 150000002367 halogens Chemical class 0.000 claims 17
- 125000003545 alkoxy group Chemical group 0.000 claims 15
- 229910052739 hydrogen Inorganic materials 0.000 claims 15
- 239000001257 hydrogen Substances 0.000 claims 15
- 125000000753 cycloalkyl group Chemical group 0.000 claims 14
- 125000001072 heteroaryl group Chemical group 0.000 claims 14
- 125000000623 heterocyclic group Chemical group 0.000 claims 13
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 12
- -1 phenoxy, amino Chemical group 0.000 claims 12
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 12
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 10
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 9
- 125000004663 dialkyl amino group Chemical group 0.000 claims 8
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 8
- 125000003342 alkenyl group Chemical group 0.000 claims 7
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 claims 7
- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims 6
- 125000004448 alkyl carbonyl group Chemical group 0.000 claims 6
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 5
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 claims 5
- 229910052801 chlorine Inorganic materials 0.000 claims 5
- 239000000460 chlorine Substances 0.000 claims 5
- 125000004473 dialkylaminocarbonyl group Chemical group 0.000 claims 5
- 229910052731 fluorine Inorganic materials 0.000 claims 5
- 239000011737 fluorine Substances 0.000 claims 5
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 5
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 150000004677 hydrates Chemical class 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 3
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims 3
- 229910052757 nitrogen Inorganic materials 0.000 claims 3
- 125000004433 nitrogen atom Chemical group N* 0.000 claims 3
- 239000012453 solvate Substances 0.000 claims 3
- 208000035143 Bacterial infection Diseases 0.000 claims 2
- 125000000304 alkynyl group Chemical group 0.000 claims 2
- 229910052799 carbon Inorganic materials 0.000 claims 2
- 125000004432 carbon atom Chemical group C* 0.000 claims 2
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- 229940127557 pharmaceutical product Drugs 0.000 claims 2
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 claims 2
- 125000006570 (C5-C6) heteroaryl group Chemical group 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 239000000654 additive Substances 0.000 claims 1
- 230000000996 additive effect Effects 0.000 claims 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 claims 1
- 230000000844 anti-bacterial effect Effects 0.000 claims 1
- 125000005141 aryl amino sulfonyl group Chemical group 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 claims 1
- 125000004472 dialkylaminosulfonyl group Chemical group 0.000 claims 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 claims 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims 1
- 125000000959 isobutyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])* 0.000 claims 1
- 125000001972 isopentyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])C([H])([H])* 0.000 claims 1
- 125000001160 methoxycarbonyl group Chemical group [H]C([H])([H])OC(*)=O 0.000 claims 1
- 125000001624 naphthyl group Chemical group 0.000 claims 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims 1
- 125000004076 pyridyl group Chemical group 0.000 claims 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10156894A DE10156894A1 (de) | 2001-11-20 | 2001-11-20 | Harnstoffe |
| PCT/EP2002/012428 WO2003043982A1 (de) | 2001-11-20 | 2002-11-07 | Derivate von andrimid und moiramid b mit antibakteriellen eigenschaften |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005514361A JP2005514361A (ja) | 2005-05-19 |
| JP2005514361A5 true JP2005514361A5 (https=) | 2006-01-05 |
| JP4476626B2 JP4476626B2 (ja) | 2010-06-09 |
Family
ID=7706325
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545619A Expired - Lifetime JP4476626B2 (ja) | 2001-11-20 | 2002-11-07 | 抗細菌性を有するアンドルイミドおよびモイルアミドｂの誘導体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7544709B2 (https=) |
| EP (1) | EP1448521B1 (https=) |
| JP (1) | JP4476626B2 (https=) |
| AU (1) | AU2002366192A1 (https=) |
| CA (1) | CA2467471C (https=) |
| DE (2) | DE10156894A1 (https=) |
| ES (1) | ES2250745T3 (https=) |
| WO (1) | WO2003043982A1 (https=) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868203A (en) * | 1986-06-02 | 1989-09-19 | Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo | Bacterial substance and pharmaceutical composition thereof |
| JPH01301657A (ja) * | 1988-05-28 | 1989-12-05 | Suntory Ltd | 新規アンドリミド誘導体 |
| JP2004501191A (ja) * | 2000-06-28 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | カルベジロール |
-
2001
- 2001-11-20 DE DE10156894A patent/DE10156894A1/de not_active Withdrawn
-
2002
- 2002-11-07 US US10/496,058 patent/US7544709B2/en not_active Expired - Fee Related
- 2002-11-07 DE DE50204419T patent/DE50204419D1/de not_active Expired - Lifetime
- 2002-11-07 WO PCT/EP2002/012428 patent/WO2003043982A1/de not_active Ceased
- 2002-11-07 JP JP2003545619A patent/JP4476626B2/ja not_active Expired - Lifetime
- 2002-11-07 EP EP02803358A patent/EP1448521B1/de not_active Expired - Lifetime
- 2002-11-07 CA CA2467471A patent/CA2467471C/en not_active Expired - Fee Related
- 2002-11-07 AU AU2002366192A patent/AU2002366192A1/en not_active Abandoned
- 2002-11-07 ES ES02803358T patent/ES2250745T3/es not_active Expired - Lifetime
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