JP2005509160A - C型肝炎ウイルス侵入阻害剤のスクリーニング - Google Patents

C型肝炎ウイルス侵入阻害剤のスクリーニング Download PDF

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Publication number
JP2005509160A
JP2005509160A JP2003542928A JP2003542928A JP2005509160A JP 2005509160 A JP2005509160 A JP 2005509160A JP 2003542928 A JP2003542928 A JP 2003542928A JP 2003542928 A JP2003542928 A JP 2003542928A JP 2005509160 A JP2005509160 A JP 2005509160A
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hcv
binding
polypeptide
cell
cells
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JP2005509160A5 (https=
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コルテーゼ,リカルド
スカルセツリ,エリーザ
ビツテリ,アレツサンドラ
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イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー
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Publication of JP2005509160A publication Critical patent/JP2005509160A/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/18Togaviridae; Flaviviridae
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2003542928A 2001-11-09 2002-11-01 C型肝炎ウイルス侵入阻害剤のスクリーニング Withdrawn JP2005509160A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34450401P 2001-11-09 2001-11-09
PCT/EP2002/012272 WO2003040726A2 (en) 2001-11-09 2002-11-01 Screening for hepatitis c virus entry inhibitors

Publications (2)

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JP2005509160A true JP2005509160A (ja) 2005-04-07
JP2005509160A5 JP2005509160A5 (https=) 2006-01-05

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JP2003542928A Withdrawn JP2005509160A (ja) 2001-11-09 2002-11-01 C型肝炎ウイルス侵入阻害剤のスクリーニング

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US (1) US20050019751A1 (https=)
EP (1) EP1444523B1 (https=)
JP (1) JP2005509160A (https=)
AT (1) ATE491952T1 (https=)
CA (1) CA2465731A1 (https=)
DE (1) DE60238633D1 (https=)
WO (1) WO2003040726A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0315248D0 (en) * 2003-06-30 2003-08-06 Hoffmann La Roche HCV regulated protein expression
AU2005262006B2 (en) * 2004-07-08 2011-01-27 Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa Antigen binding proteins directed against scavenger receptor B1 that inhibit HCV replication
WO2006103493A1 (en) * 2005-03-29 2006-10-05 Epixis Methods for enhancing the potency of hcv neutralizing antibodies
EP1832283A1 (en) * 2006-03-09 2007-09-12 Cenix Bioscience GmbH Use of inhibitors of scavenger receptor class proteins for the treatment of infectious diseases
US20090324580A1 (en) 2006-03-09 2009-12-31 Cenix Bioscience Gmbh Use of Inhibitors of Scavenger Receptor Class Proteins for the Treatment of Infectious Diseases
WO2008013918A2 (en) * 2006-07-26 2008-01-31 Myelin Repair Foundation, Inc. Cell cycle regulation and differentiation
US9052321B2 (en) * 2008-10-03 2015-06-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Flavivirus-based system for production of hepatitis C virus (HCV)
WO2017081595A1 (en) * 2015-11-12 2017-05-18 Sabic Global Technologies B.V. Methods for producing aromatics and olefins
CN112121168B (zh) * 2020-04-09 2022-03-04 中国人民解放军军事科学院军事医学研究院 一种抑制剂在制备治疗SARS-CoV-2肺炎及其并发症的药物中的应用
JP2025531751A (ja) * 2022-09-07 2025-09-25 ユナイテッド キングダム リサーチ アンド イノベーション 代謝関連疾患のための治療薬

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270939B (it) * 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
US5925333A (en) * 1995-11-15 1999-07-20 Massachusetts Institute Of Technology Methods for modulation of lipid uptake
US5998141A (en) * 1997-07-10 1999-12-07 Millennium Pharmaceuticals, Inc. Intronic and polymorphic SR-BI nucleic acids and uses therefor

Also Published As

Publication number Publication date
US20050019751A1 (en) 2005-01-27
CA2465731A1 (en) 2003-05-15
EP1444523A2 (en) 2004-08-11
WO2003040726A3 (en) 2003-12-18
WO2003040726A2 (en) 2003-05-15
DE60238633D1 (de) 2011-01-27
ATE491952T1 (de) 2011-01-15
EP1444523B1 (en) 2010-12-15

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