JP2005508963A5 - - Google Patents
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- Publication number
- JP2005508963A5 JP2005508963A5 JP2003535803A JP2003535803A JP2005508963A5 JP 2005508963 A5 JP2005508963 A5 JP 2005508963A5 JP 2003535803 A JP2003535803 A JP 2003535803A JP 2003535803 A JP2003535803 A JP 2003535803A JP 2005508963 A5 JP2005508963 A5 JP 2005508963A5
- Authority
- JP
- Japan
- Prior art keywords
- salmeterol
- medicament
- fluticasone propionate
- physiologically acceptable
- pharmaceutical formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical compound C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 claims 5
- 229960004017 salmeterol Drugs 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- 239000011780 sodium chloride Substances 0.000 claims 5
- 239000003814 drug Substances 0.000 claims 4
- 208000006673 Asthma Diseases 0.000 claims 3
- WMWTYOKRWGGJOA-CENSZEJFSA-N Fluticasone propionate Chemical compound C1([C@@H](F)C2)=CC(=O)C=C[C@]1(C)[C@]1(F)[C@@H]2[C@@H]2C[C@@H](C)[C@@](C(=O)SCF)(OC(=O)CC)[C@@]2(C)C[C@@H]1O WMWTYOKRWGGJOA-CENSZEJFSA-N 0.000 claims 3
- 229960000289 fluticasone propionate Drugs 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 229950000339 Xinafoate Drugs 0.000 claims 2
- 239000003937 drug carrier Substances 0.000 claims 2
- 239000000546 pharmaceutic aid Substances 0.000 claims 2
- 239000000825 pharmaceutical preparation Substances 0.000 claims 2
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Claims (9)
- １日１回の基準で喘息を予防または治療するための医薬を製造するためのサルメテロールまたはその生理学的に許容される塩とフルチカゾンプロピオネートの組み合わせの使用。
- 前記医薬が組み合せた医薬製剤である請求項１に記載の使用。
- 前記医薬が吸入による投与に好適である請求項１または２に記載の使用。
- 前記サルメテロールがそのキシナホエート塩の形態にある請求項１〜３のいずれか１項の記載の使用。
- サルメテロールまたはその生理学的に許容される塩とフルチカゾンプロピオネート、医薬的に許容される担体または賦形剤、場合によっては１以上の他の治療薬を含む１日１回の基準で喘息を予防または治療するための医薬製剤。
- 吸入による投与に好適な形態にある請求項５に記載の医薬製剤。
- 前記サルメテロールがそのキシナホエート塩の形態にある請求項５または６に記載の医薬製剤。
- 前記医薬的に許容される担体または賦形剤がラクトースである請求項５〜７のいずれか１項に記載の医薬製剤。
- １日１回の喘息の治療で使用されるためのサルメテロールまたはその生理学的に許容される塩とフルチカゾンプロピオネート。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0124523.2A GB0124523D0 (en) | 2001-10-12 | 2001-10-12 | Pharmaceutical combination |
| PCT/GB2002/004602 WO2003033000A1 (en) | 2001-10-12 | 2002-10-10 | Pharmaceutical combinations comprising salmeterol and fluticasone proprionate for the treatment of asthma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005508963A JP2005508963A (ja) | 2005-04-07 |
| JP2005508963A5 true JP2005508963A5 (ja) | 2006-01-05 |
Family
ID=9923709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003535803A Pending JP2005508963A (ja) | 2001-10-12 | 2002-10-10 | 喘息を治療するためのサルメテロールとフルチカゾンプロピオネートを含む医薬の組み合せ |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20050042171A1 (ja) |
| EP (1) | EP1434587A1 (ja) |
| JP (1) | JP2005508963A (ja) |
| AU (1) | AU2002334126B2 (ja) |
| CA (1) | CA2463435A1 (ja) |
| GB (1) | GB0124523D0 (ja) |
| WO (1) | WO2003033000A1 (ja) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2389530B (en) | 2002-06-14 | 2007-01-10 | Cipla Ltd | Pharmaceutical compositions |
| GB0324918D0 (en) * | 2003-10-24 | 2003-11-26 | Glaxo Group Ltd | Composition |
| ATE552032T1 (de) | 2005-07-14 | 2012-04-15 | Lithera Inc | Verbesserte lipolytikum-formulierung mit hinhaltender wirkstofffreigabe für die arealbehandlung von fettgewebe |
| WO2007096782A2 (en) * | 2006-02-22 | 2007-08-30 | Valorisation Recherche Hscm, Limited Partnership | Compositions for disorders associated wtth metachromatic cell activation |
| EP1894568A1 (en) * | 2006-08-31 | 2008-03-05 | Novartis AG | Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases |
| AU2007313077B2 (en) * | 2006-10-17 | 2011-06-02 | Neothetics, Inc. | Methods, compositions, and formulations for the treatment of thyroid eye disease |
| US9132084B2 (en) | 2009-05-27 | 2015-09-15 | Neothetics, Inc. | Methods for administration and formulations for the treatment of regional adipose tissue |
| TR201000685A2 (tr) * | 2010-01-29 | 2011-08-22 | Bi̇lgi̇ç Mahmut | Salmeterol ve flutikazon içeren farmasötik preparatlar. |
| GB2485885B (en) | 2010-11-24 | 2015-06-17 | Neothetics Inc | Selective, lipophilic, and long-acting beta agonist monotherapeutic formulations and methods for the cosmetic treatment of adiposity and contour bulging |
| JP2016523823A (ja) * | 2013-04-29 | 2016-08-12 | サノフィ・ソシエテ・アノニム | 吸入可能な医薬組成物およびこれを含む吸入器デバイス |
| WO2015054124A2 (en) * | 2013-10-07 | 2015-04-16 | Teva Branded Pharmaceutical Products R&D, Inc. | Dry powder inhaler |
| MA41378A (fr) * | 2015-01-20 | 2017-11-28 | Teva Branded Pharmaceutical Prod R & D Inc | Inhalateur de poudre sèche comprenant du propionate de fluticasone et du xinafoate de salmétérol |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270305A (en) * | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
| GB2235627B (en) * | 1989-09-08 | 1993-09-01 | Glaxo Group Ltd | Inhalation medicaments for treating respiratory disorders |
| IL104068A (en) * | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant |
| GB9924992D0 (en) * | 1999-10-21 | 1999-12-22 | Glaxo Group Ltd | Pharmaceutical aerosol formulations |
| GB0021927D0 (en) * | 2000-09-07 | 2000-10-25 | Glaxo Group Ltd | Use of pharmaceutical combination |
-
2001
- 2001-10-12 GB GBGB0124523.2A patent/GB0124523D0/en not_active Ceased
-
2002
- 2002-10-10 AU AU2002334126A patent/AU2002334126B2/en not_active Ceased
- 2002-10-10 EP EP02801377A patent/EP1434587A1/en not_active Withdrawn
- 2002-10-10 US US10/492,780 patent/US20050042171A1/en not_active Abandoned
- 2002-10-10 JP JP2003535803A patent/JP2005508963A/ja active Pending
- 2002-10-10 WO PCT/GB2002/004602 patent/WO2003033000A1/en active IP Right Grant
- 2002-10-10 CA CA002463435A patent/CA2463435A1/en not_active Abandoned
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