JP2005504523A - 低酸素圧下で発現するマイコバクテリア抗原 - Google Patents

低酸素圧下で発現するマイコバクテリア抗原 Download PDF

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Publication number
JP2005504523A
JP2005504523A JP2003507124A JP2003507124A JP2005504523A JP 2005504523 A JP2005504523 A JP 2005504523A JP 2003507124 A JP2003507124 A JP 2003507124A JP 2003507124 A JP2003507124 A JP 2003507124A JP 2005504523 A JP2005504523 A JP 2005504523A
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JP
Japan
Prior art keywords
gene
peptide
dissolved oxygen
tuberculosis
air saturation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003507124A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005504523A5 (enExample
Inventor
ウィリアム ジェイムズ，ブライアン
ベーコン，ジョアンナ
マーシュ，フィリップ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Public Health England
Original Assignee
Health Protection Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0115365A external-priority patent/GB0115365D0/en
Priority claimed from GB0121780A external-priority patent/GB0121780D0/en
Application filed by Health Protection Agency filed Critical Health Protection Agency
Publication of JP2005504523A publication Critical patent/JP2005504523A/ja
Publication of JP2005504523A5 publication Critical patent/JP2005504523A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2003507124A 2001-06-22 2002-06-21 低酸素圧下で発現するマイコバクテリア抗原 Pending JP2005504523A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0115365A GB0115365D0 (en) 2001-06-22 2001-06-22 Mycobacterial antigens expressed under low oxygen tension
GB0121780A GB0121780D0 (en) 2001-09-07 2001-09-07 Mycobacterial antigens expressed under low oxygen tension
PCT/GB2002/002845 WO2003000721A2 (en) 2001-06-22 2002-06-21 Mycobacterial antigens expressed under low oxygen tension

Publications (2)

Publication Number Publication Date
JP2005504523A true JP2005504523A (ja) 2005-02-17
JP2005504523A5 JP2005504523A5 (enExample) 2005-12-22

Family

ID=26246235

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003507124A Pending JP2005504523A (ja) 2001-06-22 2002-06-21 低酸素圧下で発現するマイコバクテリア抗原

Country Status (6)

Country Link
US (3) US7393539B2 (enExample)
EP (1) EP1401867A2 (enExample)
JP (1) JP2005504523A (enExample)
AU (1) AU2002317940B9 (enExample)
CA (1) CA2451026C (enExample)
WO (1) WO2003000721A2 (enExample)

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Publication number Priority date Publication date Assignee Title
CN1350546A (zh) 1998-11-04 2002-05-22 Isis创新有限公司 结核诊断测验
US7393539B2 (en) 2001-06-22 2008-07-01 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
EP2196473A1 (en) 2001-07-04 2010-06-16 Health Protection Agency Mycobacterial antigens expressed during latency
GB0125535D0 (en) * 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
US7850970B2 (en) 2003-08-26 2010-12-14 The Regents Of The University Of Colorado Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
CN102124029A (zh) * 2008-05-26 2011-07-13 泰里安诊断有限公司 诊断由分枝杆菌引起的感染的方法和针对其的试剂
US20100159485A1 (en) * 2008-12-19 2010-06-24 Centre For Dna Fingerprinting And Diagnostics Detection of mycobacterium tuberculosis
WO2010096882A1 (en) * 2009-02-26 2010-09-02 Tyrian Diagnostics Limited Method of diagnosis of infection by mycobacteria and reagents therefor
US8367055B2 (en) 2009-05-14 2013-02-05 Wisconsin Alumni Research Foundation Immunogenic compositions against tuberculosis
GB201008512D0 (en) 2010-05-21 2010-07-07 Health Prot Agency Mycobacterial antigen composition
BR112013026929A2 (pt) * 2011-04-20 2016-12-27 Mico Bio Inc composição e método para intensificação de uma resposta imune
US9938353B2 (en) 2011-06-24 2018-04-10 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
US10703784B2 (en) * 2011-09-30 2020-07-07 La Jolla Institute For Allergy And Immunology Antigens and epitopes derived from Mycobacterium tuberculosis
US10478508B2 (en) 2012-01-10 2019-11-19 The Regents Of The University Of Colorado, A Body Corporate Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
WO2013170154A1 (en) * 2012-05-10 2013-11-14 Albert Einstein College Of Medicine Of Yeshiva University Mycobacterium tuberculosis δesx-3 mutants
US10357555B2 (en) 2012-07-10 2019-07-23 Transgene Sa Mycobacterial antigen vaccine
RU2695462C2 (ru) 2014-01-09 2019-07-23 Трансген Са Гибридизация гетероолигомерных микобактериальных антигенов
CN106237317A (zh) * 2015-06-15 2016-12-21 复旦大学 由结核分枝杆菌抗原组成的结核疫苗
WO2019224673A1 (en) * 2018-05-19 2019-11-28 Jamia Hamdard University Signature protein of mycobacterium tuberculosis and its methods of use

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9024320D0 (en) 1990-11-08 1990-12-19 Univ London Treatment of uveitis
DE4221858A1 (de) 1992-07-03 1994-01-05 Becker Carl Chemie Gmbh Addukte von 0,0-Dialkyldithiophosphorsäuren an ungesättigte Verbindungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Schmiermitteladditive
US6583266B1 (en) * 1993-08-19 2003-06-24 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to mycobacterium tuberculosis and leprae for diagnostics and therapeutics
US5783386A (en) * 1994-02-24 1998-07-21 Agresearch, New Zealand Pastoral Agriculture Research Institute Ltd. Mycobacteria virulence factors and a novel method for their identification
KR100445103B1 (ko) 1994-12-09 2004-12-04 임페리얼 컬리지 이노베이션스 리미티드 유전자의동정
US6572865B1 (en) * 1995-06-15 2003-06-03 University Of Victoria Innovation And Development Corporation Mycobacterium tuberculosis DNA sequences encoding immunostimulatory peptides and methods for using same
US5998194A (en) * 1995-12-21 1999-12-07 Abbott Laboratories Polyketide-associated sugar biosynthesis genes
CA2197524A1 (en) * 1996-02-22 1997-08-22 Bradley Stuart Dehoff Polyketide synthase genes
EP0910403A1 (en) 1996-03-27 1999-04-28 The Johns-Hopkins University Stationary phase, stress response sigma factor from mycobacterium tuberculosis, and regulation thereof
IL129389A0 (en) 1996-10-11 2000-02-17 Corixa Corp Compounds and methods for diagnsosis of tuberculosis
US6555653B2 (en) 1997-05-20 2003-04-29 Corixa Corporation Compounds for diagnosis of tuberculosis and methods for their use
GB9711389D0 (en) 1997-06-04 1997-07-30 Univ Wales The Bacterial pheromones and uses therefor
EP1003870A1 (en) 1997-07-16 2000-05-31 Institut Pasteur A polynucleotide functionally coding for the lhp protein from mycobacterium tuberculosis, its biologically active derivative fragments, as well as methods using the same
AU9200398A (en) 1997-08-22 1999-03-16 Yale University A process to study changes in gene expression in granulocytic cells
GB9723630D0 (en) 1997-11-07 1998-01-07 Stanford Rook Ltd M.vaccae preparation and its use
US6183957B1 (en) * 1998-04-16 2001-02-06 Institut Pasteur Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library application to the detection of mycobacteria
EP1075485A4 (en) 1998-05-05 2004-12-15 Gene Logic Inc METHOD FOR STUDYING MODIFICATIONS OF GENE EXPRESSION IN T CELLS
US6892139B2 (en) * 1999-01-29 2005-05-10 The Regents Of The University Of California Determining the functions and interactions of proteins by comparative analysis
GB9904773D0 (en) 1999-03-02 1999-04-28 Microbiological Res Authority Culture of mycobacteria
US6573361B1 (en) * 1999-12-06 2003-06-03 Monsanto Technology Llc Antifungal proteins and methods for their use
US6613553B1 (en) * 2000-02-04 2003-09-02 St. Jude Children's Research Hospital Enoyl reductases and methods of use thereof
WO2002077183A2 (en) 2001-03-21 2002-10-03 Elitra Pharmaceuticals, Inc. Identification of essential genes in microorganisms
US7393539B2 (en) * 2001-06-22 2008-07-01 Health Protection Agency Mycobacterial antigens expressed under low oxygen tension
EP2196473A1 (en) * 2001-07-04 2010-06-16 Health Protection Agency Mycobacterial antigens expressed during latency
GB0125535D0 (en) 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency

Also Published As

Publication number Publication date
US7393539B2 (en) 2008-07-01
WO2003000721A2 (en) 2003-01-03
WO2003000721A3 (en) 2003-06-26
CA2451026C (en) 2013-12-10
US8404826B2 (en) 2013-03-26
AU2002317940B9 (en) 2008-06-05
AU2002317940B2 (en) 2007-12-20
US20090054367A1 (en) 2009-02-26
US20120088297A1 (en) 2012-04-12
CA2451026A1 (en) 2003-01-03
US20040254349A1 (en) 2004-12-16
US8017753B2 (en) 2011-09-13
EP1401867A2 (en) 2004-03-31

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