JP2005503383A5 - - Google Patents
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- Publication number
- JP2005503383A5 JP2005503383A5 JP2003520752A JP2003520752A JP2005503383A5 JP 2005503383 A5 JP2005503383 A5 JP 2005503383A5 JP 2003520752 A JP2003520752 A JP 2003520752A JP 2003520752 A JP2003520752 A JP 2003520752A JP 2005503383 A5 JP2005503383 A5 JP 2005503383A5
- Authority
- JP
- Japan
- Prior art keywords
- adrenal
- pharmaceutical composition
- hydrocortisone
- disease
- caused
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 claims 20
- 230000001919 adrenal effect Effects 0.000 claims 12
- 229960000890 hydrocortisone Drugs 0.000 claims 10
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 230000004064 dysfunction Effects 0.000 claims 8
- 206010010356 Congenital anomaly Diseases 0.000 claims 6
- 208000026872 Addison Disease Diseases 0.000 claims 4
- 206010020880 Hypertrophy Diseases 0.000 claims 4
- 208000025302 chronic primary adrenal insufficiency Diseases 0.000 claims 4
- 208000020576 Adrenal disease Diseases 0.000 claims 2
- 206010001367 Adrenal insufficiency Diseases 0.000 claims 2
- ITRJWOMZKQRYTA-RFZYENFJSA-N Cortisone acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)CC2=O ITRJWOMZKQRYTA-RFZYENFJSA-N 0.000 claims 2
- 206010036049 Polycystic ovaries Diseases 0.000 claims 2
- 208000017515 adrenocortical insufficiency Diseases 0.000 claims 2
- 229960003290 cortisone acetate Drugs 0.000 claims 2
- 230000003111 delayed effect Effects 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 201000010065 polycystic ovary syndrome Diseases 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000002459 sustained effect Effects 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0119848.0A GB0119848D0 (en) | 2001-08-15 | 2001-08-15 | Delayed and sustained drug release |
| PCT/GB2002/003631 WO2003015793A1 (en) | 2001-08-15 | 2002-08-08 | Delayed and sustained drug release |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005503383A JP2005503383A (ja) | 2005-02-03 |
| JP2005503383A5 true JP2005503383A5 (enExample) | 2006-01-05 |
Family
ID=9920405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003520752A Pending JP2005503383A (ja) | 2001-08-15 | 2002-08-08 | 遅らせかつ持続された薬剤放出 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20050037074A1 (enExample) |
| EP (1) | EP1416938A1 (enExample) |
| JP (1) | JP2005503383A (enExample) |
| CA (1) | CA2493349A1 (enExample) |
| GB (1) | GB0119848D0 (enExample) |
| WO (1) | WO2003015793A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1448205T1 (sl) * | 2001-10-05 | 2011-07-29 | Zalicus Inc | Kombinacije za zdravljenje imunoinflamatornih motenj |
| TW200517114A (en) * | 2003-10-15 | 2005-06-01 | Combinatorx Inc | Methods and reagents for the treatment of immunoinflammatory disorders |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| SE0401031D0 (sv) | 2004-04-22 | 2004-04-22 | Duocort Ab | A new glucocorticoid replacement therapy |
| WO2007139753A2 (en) * | 2006-05-22 | 2007-12-06 | Combinatorx, Incorporated | Methods and compositions for the treatment of diseases or conditions associated with increased c-reactive protein, interleukin-6, or interferon-gamma levels |
| GB0623740D0 (en) * | 2006-11-28 | 2007-01-10 | Diurnal Ltd | Treatment of disease |
| US20090075955A1 (en) * | 2007-09-19 | 2009-03-19 | Combinatorx, Inc. | Therapeutic regimens for the treatment of immunoinflammatory disorders |
| CN101938996A (zh) * | 2007-12-17 | 2011-01-05 | 康宾纳特克斯公司 | 用于治疗免疫炎症性紊乱的治疗方案 |
| GB0817120D0 (en) * | 2008-09-19 | 2008-10-29 | Diurnal Ltd | Treatment of adrenal insufficiency |
| CA2757858C (en) * | 2009-04-07 | 2017-03-28 | Duocort Pharma Ab | Improved glucocorticoid therapy |
| SG185457A1 (en) | 2010-05-20 | 2012-12-28 | Duocort Pharma Ab | Posology and administration of glucocorticoid based compositions |
| GB201202433D0 (en) | 2012-02-13 | 2012-03-28 | Diurnal Ltd | Controlled drug release |
| MX383353B (es) * | 2015-03-30 | 2025-03-13 | Corcept Therapeutics Inc | Uso de antagonistas de receptores de glucocorticoides en combinacion con glucocorticoides para tratar la insuficiencia adrenal. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5792476A (en) * | 1996-12-19 | 1998-08-11 | Abigo Medical Ab | Sustained release glucocorticoid pharmaceutical composition |
| US5788987A (en) * | 1997-01-29 | 1998-08-04 | Poli Industria Chimica Spa | Methods for treating early morning pathologies |
| DE19718012C1 (de) * | 1997-04-29 | 1998-10-08 | Jenapharm Gmbh | Verfahren zur Herstellung peroral anwendbarer fester Arzneiformen mit gesteuerter Wirkstoffabgabe |
| DE10012555A1 (de) * | 2000-03-15 | 2001-09-20 | Merck Patent Gmbh | Glucocorticoide in einer Modified Release-Formulierung |
-
2001
- 2001-08-15 GB GBGB0119848.0A patent/GB0119848D0/en not_active Ceased
-
2002
- 2002-08-08 WO PCT/GB2002/003631 patent/WO2003015793A1/en not_active Ceased
- 2002-08-08 CA CA002493349A patent/CA2493349A1/en not_active Abandoned
- 2002-08-08 JP JP2003520752A patent/JP2005503383A/ja active Pending
- 2002-08-08 EP EP02751394A patent/EP1416938A1/en not_active Withdrawn
- 2002-08-08 US US10/486,700 patent/US20050037074A1/en not_active Abandoned
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