JP2005502866A5 - - Google Patents
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- Publication number
- JP2005502866A5 JP2005502866A5 JP2003526688A JP2003526688A JP2005502866A5 JP 2005502866 A5 JP2005502866 A5 JP 2005502866A5 JP 2003526688 A JP2003526688 A JP 2003526688A JP 2003526688 A JP2003526688 A JP 2003526688A JP 2005502866 A5 JP2005502866 A5 JP 2005502866A5
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- ejector
- reservoir
- droplet
- reservoirs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims 37
- 238000000034 method Methods 0.000 claims 26
- 230000005855 radiation Effects 0.000 claims 18
- 239000000758 substrate Substances 0.000 claims 12
- 230000008878 coupling Effects 0.000 claims 3
- 238000010168 coupling process Methods 0.000 claims 3
- 238000005859 coupling reaction Methods 0.000 claims 3
- 238000001816 cooling Methods 0.000 claims 2
- 150000008282 halocarbons Chemical group 0.000 claims 2
- 239000003960 organic solvent Substances 0.000 claims 2
- 230000003213 activating effect Effects 0.000 claims 1
- 150000001298 alcohols Chemical class 0.000 claims 1
- 150000001299 aldehydes Chemical class 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 150000001412 amines Chemical class 0.000 claims 1
- 150000001735 carboxylic acids Chemical class 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 150000002170 ethers Chemical class 0.000 claims 1
- 229930195733 hydrocarbon Natural products 0.000 claims 1
- 150000002430 hydrocarbons Chemical class 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 150000003951 lactams Chemical class 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 150000002825 nitriles Chemical class 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 229940082615 organic nitrates used in cardiac disease Drugs 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 150000003568 thioethers Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/910,690 US6416164B1 (en) | 2001-07-20 | 2001-07-20 | Acoustic ejection of fluids using large F-number focusing elements |
| PCT/US2002/017656 WO2003022583A1 (en) | 2001-07-20 | 2002-06-04 | Acoustic ejection of fluids using large f-number focusing elements |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005502866A JP2005502866A (ja) | 2005-01-27 |
| JP2005502866A5 true JP2005502866A5 (enExample) | 2008-09-18 |
| JP4189964B2 JP4189964B2 (ja) | 2008-12-03 |
Family
ID=25429185
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003526688A Expired - Lifetime JP4189964B2 (ja) | 2001-07-20 | 2002-06-04 | 大きいｆ番号の集束要素を使用する流体の音波射出 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6416164B1 (enExample) |
| EP (1) | EP1409254B1 (enExample) |
| JP (1) | JP4189964B2 (enExample) |
| CA (1) | CA2452470C (enExample) |
| ES (1) | ES2651538T3 (enExample) |
| WO (1) | WO2003022583A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6666541B2 (en) * | 2000-09-25 | 2003-12-23 | Picoliter Inc. | Acoustic ejection of fluids from a plurality of reservoirs |
| JP4990476B2 (ja) * | 2000-09-25 | 2012-08-01 | ピコリター インコーポレイテッド | コンビナトリアルライブラリの調製およびスクリーニングにおける集束された音響エネルギー |
| US6849423B2 (en) * | 2000-11-29 | 2005-02-01 | Picoliter Inc | Focused acoustics for detection and sorting of fluid volumes |
| US6893836B2 (en) * | 2000-11-29 | 2005-05-17 | Picoliter Inc. | Spatially directed ejection of cells from a carrier fluid |
| US7332127B2 (en) * | 2001-07-11 | 2008-02-19 | University Of Southern California | DNA probe synthesis on chip on demand by MEMS ejector array |
| US7354141B2 (en) | 2001-12-04 | 2008-04-08 | Labcyte Inc. | Acoustic assessment of characteristics of a fluid relevant to acoustic ejection |
| US6893115B2 (en) | 2002-09-20 | 2005-05-17 | Picoliter Inc. | Frequency correction for drop size control |
| US6874699B2 (en) | 2002-10-15 | 2005-04-05 | Wisconsin Alumni Research Foundation | Methods and apparata for precisely dispensing microvolumes of fluids |
| US6979073B2 (en) | 2002-12-18 | 2005-12-27 | Xerox Corporation | Method and apparatus to pull small amounts of fluid from n-well plates |
| US6827287B2 (en) * | 2002-12-24 | 2004-12-07 | Palo Alto Research Center, Incorporated | High throughput method and apparatus for introducing biological samples into analytical instruments |
| US7070260B2 (en) * | 2003-01-09 | 2006-07-04 | Labcyte Inc. | Droplet dispensation from a reservoir with reduction in uncontrolled electrostatic charge |
| US6916083B2 (en) * | 2003-09-22 | 2005-07-12 | Labcyte Inc. | Control over flow of an acoustic coupling fluid |
| US20050175683A1 (en) * | 2003-10-24 | 2005-08-11 | Yuanpeng Zhang | Preparation of lipid particles |
| US7334871B2 (en) * | 2004-03-26 | 2008-02-26 | Hewlett-Packard Development Company, L.P. | Fluid-ejection device and methods of forming same |
| US10112212B1 (en) | 2004-04-08 | 2018-10-30 | Labcyte Inc. | Droplet ejection using focused acoustic radiation having a plurality of frequency ranges |
| US7445315B2 (en) * | 2004-11-15 | 2008-11-04 | Palo Alto Research Center Incorporated | Thin film and thick film heater and control architecture for a liquid drop ejector |
| US20060210443A1 (en) * | 2005-03-14 | 2006-09-21 | Stearns Richard G | Avoidance of bouncing and splashing in droplet-based fluid transport |
| US7607347B2 (en) * | 2006-03-07 | 2009-10-27 | Gems Sensors, Inc. | Fluid level detector |
| EP2021103B1 (en) | 2006-05-09 | 2017-07-12 | Advanced Liquid Logic, Inc. | Electrowetting droplet microactuator controlled via graphical user interface |
| US8053191B2 (en) | 2006-08-31 | 2011-11-08 | Westend Asset Clearinghouse Company, Llc | Iterative nucleic acid assembly using activation of vector-encoded traits |
| US9192932B2 (en) * | 2007-06-20 | 2015-11-24 | Labcyte Inc. | Closures which contain reservoirs and allow acoustic ejection |
| US7753636B2 (en) * | 2008-03-25 | 2010-07-13 | Hennig Emmett D | Adjustable bale mover spikes |
| WO2010025310A2 (en) | 2008-08-27 | 2010-03-04 | Westend Asset Clearinghouse Company, Llc | Methods and devices for high fidelity polynucleotide synthesis |
| WO2011056872A2 (en) | 2009-11-03 | 2011-05-12 | Gen9, Inc. | Methods and microfluidic devices for the manipulation of droplets in high fidelity polynucleotide assembly |
| WO2011066185A1 (en) | 2009-11-25 | 2011-06-03 | Gen9, Inc. | Microfluidic devices and methods for gene synthesis |
| EP2504449B1 (en) | 2009-11-25 | 2016-03-23 | Gen9, Inc. | Methods and apparatuses for chip-based dna error reduction |
| WO2011085075A2 (en) | 2010-01-07 | 2011-07-14 | Gen9, Inc. | Assembly of high fidelity polynucleotides |
| CA2817697C (en) | 2010-11-12 | 2021-11-16 | Gen9, Inc. | Methods and devices for nucleic acids synthesis |
| WO2012064975A1 (en) | 2010-11-12 | 2012-05-18 | Gen9, Inc. | Protein arrays and methods of using and making the same |
| US9752176B2 (en) | 2011-06-15 | 2017-09-05 | Ginkgo Bioworks, Inc. | Methods for preparative in vitro cloning |
| JP2014526899A (ja) | 2011-08-26 | 2014-10-09 | ジェン９・インコーポレイテッド | 核酸の高忠実度アセンブリのための組成物および方法 |
| US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
| CA2871505C (en) | 2012-04-24 | 2021-10-12 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
| WO2014004393A1 (en) | 2012-06-25 | 2014-01-03 | Gen9, Inc. | Methods for nucleic acid assembly and high throughput sequencing |
| US10156499B1 (en) | 2012-10-01 | 2018-12-18 | Labcyte Inc. | Focused acoustic radiation for the ejection of subwavelength droplets |
| JP6592849B2 (ja) * | 2014-01-21 | 2019-10-23 | プロメディカ バイオエレクトロニクス エス．アール．エル． | 超音波試験のための装置 |
| US9939352B2 (en) | 2014-10-17 | 2018-04-10 | Labcyte, Inc. | Method and system for determining the concentration of an analyte in a fluid sample |
| US10787670B2 (en) | 2016-09-15 | 2020-09-29 | Labcyte Inc. | High-efficiency transfection of biological cells using sonoporation |
| CN122193614A (zh) | 2017-11-22 | 2026-06-12 | 拉伯塞特股份有限公司 | 使用连续流动采样探针对分析仪器进行声学加载的系统和方法 |
| CN112236519A (zh) | 2018-03-03 | 2021-01-15 | 拉伯塞特股份有限公司 | 使用声学液滴喷射从样品中提取目标部分的系统和方法 |
| US11898993B2 (en) | 2018-03-30 | 2024-02-13 | Labcyte, Inc. | Fluid impermeable ultrasonic transducer |
| AU2019370221B2 (en) * | 2018-10-29 | 2023-05-11 | Labcyte Inc. | Acoustic droplet ejection of non-Newtonian fluids |
| CA3127492C (en) | 2019-02-01 | 2023-10-03 | Labcyte Inc. | Acoustic concentration, transfer and analysis of samples containing particles |
| US20250308871A1 (en) * | 2022-05-10 | 2025-10-02 | Dh Technologies Development Pte. Ltd. | Systems and methods for automatic sample re-runs in sample analysys |
| CN121001813A (zh) * | 2023-02-24 | 2025-11-21 | 拉伯赛特股份有限公司 | 声学液滴喷射的动态表面分析 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4308547A (en) | 1978-04-13 | 1981-12-29 | Recognition Equipment Incorporated | Liquid drop emitter |
| US4697195A (en) | 1985-09-16 | 1987-09-29 | Xerox Corporation | Nozzleless liquid droplet ejectors |
| US4697105A (en) | 1986-07-23 | 1987-09-29 | American Telephone And Telegraph Company, At&T Bell Laboratories | CMOS programmable logic array |
| US4751529A (en) | 1986-12-19 | 1988-06-14 | Xerox Corporation | Microlenses for acoustic printing |
| US5041849A (en) | 1989-12-26 | 1991-08-20 | Xerox Corporation | Multi-discrete-phase Fresnel acoustic lenses and their application to acoustic ink printing |
| US5229793A (en) * | 1990-12-26 | 1993-07-20 | Xerox Corporation | Liquid surface control with an applied pressure signal in acoustic ink printing |
| JPH11151810A (ja) * | 1997-11-21 | 1999-06-08 | Toshiba Corp | インクジェット記録装置 |
| US6364454B1 (en) * | 1998-09-30 | 2002-04-02 | Xerox Corporation | Acoustic ink printing method and system for improving uniformity by manipulating nonlinear characteristics in the system |
| US6548308B2 (en) | 2000-09-25 | 2003-04-15 | Picoliter Inc. | Focused acoustic energy method and device for generating droplets of immiscible fluids |
| US6806051B2 (en) | 2000-09-25 | 2004-10-19 | Picoliter Inc. | Arrays of partially nonhybridizing oligonucleotides and preparation thereof using focused acoustic energy |
| DE60116794T2 (de) * | 2000-09-25 | 2006-08-31 | Picoliter, Inc., Sunnyvale | Schallausstoss von fluiden aus mehreren behältern |
| US20020061258A1 (en) | 2000-09-25 | 2002-05-23 | Mutz Mitchell W. | Focused acoustic energy in the preparation and screening of combinatorial libraries |
| US6666541B2 (en) | 2000-09-25 | 2003-12-23 | Picoliter Inc. | Acoustic ejection of fluids from a plurality of reservoirs |
| US6596239B2 (en) * | 2000-12-12 | 2003-07-22 | Edc Biosystems, Inc. | Acoustically mediated fluid transfer methods and uses thereof |
-
2001
- 2001-07-20 US US09/910,690 patent/US6416164B1/en not_active Expired - Lifetime
-
2002
- 2002-06-04 JP JP2003526688A patent/JP4189964B2/ja not_active Expired - Lifetime
- 2002-06-04 ES ES02739673.8T patent/ES2651538T3/es not_active Expired - Lifetime
- 2002-06-04 CA CA002452470A patent/CA2452470C/en not_active Expired - Lifetime
- 2002-06-04 WO PCT/US2002/017656 patent/WO2003022583A1/en not_active Ceased
- 2002-06-04 EP EP02739673.8A patent/EP1409254B1/en not_active Expired - Lifetime
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