JP2005130836A - Health supplemental food containing horse milk - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a health supplemental food containing at least 1 kind selected from a mushroom, mushroom extract and propolis extract, and improving physiological activities such as immunogenic power-improving activity and anticancer, antifungal, antibacterial, antiviral, active oxygen removal, antiinflammation activities, etc. <P>SOLUTION: This health supplemental food is obtained by combining at least 1 kind selected from the mushroom, mushroom extract and propolis, etc., with defatted powdered horse milk. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a health supplement containing horse milk.

  Until recently, horse milk that has been used only raw in its production area or its surroundings has recently been used in the form of dried skim milk powder.

  This horse milk has not only useful nutritional components, but also functional components that exert physiological functions such as immunity enhancing action, anticancer property, antibacterial / antibacterial / antiviral property, active oxygen removal effect, anti-inflammatory effect, etc. In recent years, attention has been focused on using the dried product as a dietary supplement or health supplement.

  On the other hand, agaricus mushrooms containing a large amount of β-D-glucan having a strong immunopotentiating action, Yamabushitake, Meshimakobu, Ganoderma, birch moss, or maitake mushrooms, and extracts thereof, increase immunity and prevent diseases such as cancer Since it has been scientifically clarified that it is effective and has actions such as blood sugar effect action, blood pressure stabilization action and arteriosclerosis prevention action, such agaricus sputum as well as cancer, Recently, it has been actively used as a functional food or a health supplement for the treatment or prevention of various diseases caused by other immunity weaknesses or other diseases.

  Propolis containing various specific components in addition to natural physiologically active substances such as flavonoids such as quercetin and various catechins, caffeic acid phenethyl ester and BMR-like substance is also said to be a natural antibiotic, It exhibits various actions such as strengthening action, antitumor action, active oxygen scavenging action, antibacterial / antibacterial / antiviral action, anti-inflammatory action, hypoglycemic action and skin beautifying action, so it can be used in the form of health supplements or cosmetics. It is used in the direction.

However, even the above-described sputum, propolis, and horse milk have not always exhibited the various physiological functions sufficiently, and in many cases, satisfactory results cannot be obtained.
This invention makes it a subject to improve further the said effect | action of a horse milk, a sputum, and a propolis.

  As a result of various studies to solve such problems, the inventor of the present invention includes horse milk skim milk powder in combination with at least one selected from sputum such as Agaricus sputum, sputum extract and propolis extract. In foods, it has been found that these components exert a synergistic effect on each other to further improve the above-described useful physiological activity by horse milk, straw and propolis.

The present invention was invented based on such knowledge,
The present invention relates to a health supplement characterized by containing at least one selected from salmon, persimmon extract and propolis extract and skim milk powder of horse milk.

  According to the present invention, the immunity enhancement action, antibacterial / antibacterial / antiviral activity, antioxidative activity, anticancer activity, anti-inflammatory property, and hypoglycemic activity inherent in horse milk, sputum and propolis. , Blood pressure stabilization action, liver function enhancement action, cell metabolism promotion action, intestinal function activation action, enzyme inhibitory action that adversely affects the body, vascular strengthening action, analgesic action and skin beautifying action, any of these Health supplements that are even better than one or a combination of sputum and propolis, and thus various diseases that can be healed by their physiologically active action or disorders such as poor health, loss of physical fitness or burns A health supplement effective to improve is provided.

In the health supplement of the present invention, horse milk is used in the form of skim milk powder.
This skim milk powder of horse milk is manufactured through a process as shown in the block diagram of FIG. 1, for example.

  The filtered horse milk is tested for flavor, taste, appearance and density by B's field test and then transported by truck to the factory. Horse milk carried to the factory is subjected to density and acid tests and bacteriological tests by D laboratory tests and the lipid content is measured.

  After the laboratory test, the horse milk is heated to 35-40 ° C. in a stainless steel container in the heating step E, cooled to room temperature, and then filtered through a sieve in the F filtration step. As a result, debris such as sheep's wool, wrinkles and dust is removed.

  The filtered horse milk is subjected to pasteurization treatment in which the lipid is removed (skimmed) by a separator in the separation step of G, and then heated at 72 ° C. for 15 seconds in H and then immediately cooled.

  The horse milk that has been defatted and pasteurized is dried at the inlet temperature of 50 to 60 ° C. and the outlet temperature of 42 to 45 ° C. under reduced pressure by a vacuum evaporator in the concentration step I before drying. It is concentrated until the content is about 50 to 60% of the original content. The concentrated horse milk is further filtered through a sieve in the filtration step of J, so that still remaining sheep's hair, wrinkles, dust and the like are removed.

  After concentration, the filtered horse milk is sprayed in the form of fine droplets in hot air heated to 180-200 ° C. in the drying tower of the spray dryer in the K spray drying process. At the outlet, the temperature is at most 90 to 100 ° C., and as a result, generally changes to a dry powder composed of fine particles containing about 3% by weight of water.

  In the above-described method for producing skim milk powder of horse milk, the concentrated horse milk is dried by spray drying. However, drying here may be performed by an appropriate drying method other than spray drying, such as freeze drying. It may be done by law.

  The total value of essential amino acids in the skim milk powder produced in this way is similar to that of breast milk. Especially for lactalbumin and immunoglobulin, horse milk contains more milk than cow milk. Include lactoferrin, immunoglobulin, A. G. M.M. It contains more immune defense factors such as lysozyme and enzymes such as amylase, peroxidase, phosphatase and lipase than milk from other livestock.

  Furthermore, horse milk has a higher content of lactose, potassium, vitamin C and unsaturated fatty acids than cow's milk, and in addition to exerting an action of enhancing the functions of organs such as the liver, kidney and lung, It has the effect of reducing adverse effects caused by irradiation and undesirable side effects of drugs, and also exhibits a synergistic effect that is specifically compatible with the aforementioned wrinkles and propolis, thereby enhancing the advantageous bioactive effects as described above. It has nature.

  Horse milk also contains lymphocyte activating factor (IL-1), IL-1Ra, B cell stimulating factor (IL-6), inter-feron gamma inducing factor (IL-18), TNA-α hacta and lactoferrin. In order to contain such an immune defense factor, the above-mentioned action, that is, antibacterial / antibacterial / antiviral action, tumor cell growth inhibitory action, antitumor activity action, antimicrobial activity action, anti-inflammatory action, tissue repair action , Immune system stimulating action including lymphocytes, fever, sleep, pain regulating action, antioxidant action, immune regulating action, cell growth regulating action, intestinal flora improving action, bifidobacteria growing action, iron absorption regulating action And exerts excellent physiological effects such as an active oxygen removal action.

  As the sputum used in the present invention, physiological effects such as anticancer activity, antibacterial / antibacterial / antiviral activity, active oxygen removal effect, immune enhancing effect, hypoglycemic effect, blood pressure stabilizing effect and liver function enhancing effect As a component that exerts the above, any wrinkles conventionally used in health supplements and the like can be used. Among such moths, moths such as Agaricus moth (Agaricus blazei Murrill), Yamabushitake, Meshimakobu, Bionohanatake (Inonotus obliquus), Reishi and Maitake are preferably used.

  In the dietary supplement of the present invention, these straws are generally used in a dry state such as a dry powder or an extract subjected to an extraction treatment with a solvent such as water or ethanol. The extract may be in a liquid form, or the liquid form may be a powdery or granular solid obtained by drying such as spray drying or freeze drying.

  The propolis used in the present invention may be used in the form of an extract obtained by extracting a natural resinous propolis with, for example, ethanol or water, or both. The liquid extract may be used as a powdery or granular solid obtained by drying such as spray drying.

  In the health supplement of the present invention, in order for these ingredients to exhibit a desirable synergistic effect by combining horse milk with at least one selected from the above-described salmon, salmon extract and propolis extract, salmon and horse When combining skim milk powder, for example, 30 to 80% by weight of cocoon and 20 to 70% by weight skim milk powder of horse milk are combined based on the total weight of these, and propolis extract and horse When combined with skim milk powder, based on the total weight of these, for example, when using a propolis extract containing 25% by weight of a component derived from propolis, generally 20 to 70 wt. % And 30 to 80% by weight of skim milk powder of horse milk, and when combining straw, propolis extract and skim milk powder of horse milk, In general, 30 to 80% by weight of cocoon, 20 to 70% by weight of propolis extract and 30 to 80% by weight of skim milk powder of horse milk are combined, and instead of the above cocoon, for example, cocoon For example, when a cocoon extract containing 10% by weight of a component derived from potato is used, the cocoon extract corresponding to the weight ratio of the cocoon is generally used.

  The product of the present invention reduces the image of horse milk, an image that is refrained from being easily avoided by consumers unfamiliar with it, or a relatively strong or undesirable odor derived from horse milk, straw or propolis. In order to improve the taste or texture and make the product easier to take, for example, at least one of a flavoring agent or a sweetening agent may be added thereto.

  Flavoring agents include, for example, essences derived from fruits such as mandarin orange, lemon, apple or pineapple, and flavoring agents such as vanilla, cacao or coffee, and sweeteners include, for example, sucrose, Examples thereof include glucose, fructose and lactose.

  In addition to the flavors and sweeteners as described above, the product of the present invention may optionally include a bulking agent such as starch, a thickening agent such as dextrin or gelatin, or a nutrient such as an amino acid, vitamin or mineral. Alternatively, a physiologically active ingredient may be added.

  The dietary supplement of the present invention may be in any state, and may be finished in, for example, powder, granule, liquid (fluid), paste or jelly.

  When the health food of the present invention is provided as a powder, for example, dry powder of salmon, dry powder of salmon extract, dry powder of propolis extract, and skim milk powder of horse milk, And optionally by mixing any necessary ingredients such as flavors or sweeteners in a suitable mixing device.

  This powdered food is also a solid of the above ingredients, such as skim milk powder of horse milk, dry powder of salmon, dry powder of salmon extract, dry powder of propolis extract and solid flavoring or By impregnating at least one of optional additives such as sweeteners with a liquid of the above components, for example, a liquid koji extract or a propolis extract, and then drying the mixture It may be manufactured.

  When the health food of the present invention is provided in the form of granules, for example, the powdered product produced as described above may be granulated with a suitable granulator, or the above powder, Any additional ingredients such as skim milk powder of horse milk, dry powder of salmon, dry powder of salmon extract, dry powder of propolis extract and powdery flavoring or sweeteners are also of appropriate size After granulating each, the obtained granules may be mixed with each other.

  Skim milk powder of horse milk, dry powder of salmon, dry powder of salmon extract, dry powder of propolis extract, and optionally at least two optional ingredients such as powdered flavoring or sweetener From the above-mentioned powdery product produced from these raw material components, the granular product according to the present invention is produced, for example, as follows.

  First, at least one of dry powder of persimmon, dry powder of persimmon extract and dry powder of propolis extract and skim milk powder of horse milk, and, optionally, optional additives such as flavoring agent or sweetener. The raw material components are kneaded uniformly by adding excipients, binders, disintegrants or other suitable additives to these raw material components. For this kneading, a commercially available appropriate kneading apparatus is used. .

  As the excipient, for example, starch, lactose, sucrose or glucose is used, and as this starch, corn starch, potato starch, sweet potato starch or the like is used.

  As the binder, for example, gelatin, water, gum arabic, gum tragacanth or alcohol is used.

  As the disintegrant, for example, starch is used, and when this granular product is used as a raw material for producing a tablet described later, talc, wax, stearic acid or magnesium stearate is used as necessary. Such lubricants are also mixed.

  Combining the above raw material ingredients including skim milk powder of horse milk with an additive such as a host machine, these solidify together and generally become a crusty clay, and this clay-like kneaded product is, for example, When backed by a mesh made of a stainless steel wire mesh or other materials, the kneaded material passes through the mesh, and is formed into granules having a particle size corresponding to the size of the mesh.

  Next, the granular shaped product thus produced is subjected to a drying treatment to give a product of the present invention generally containing about 3 to 7% of moisture. Any method may be used as long as it is not impaired, and for example, a drying method such as natural ventilation drying, hot air drying or fluidized bed drying is employed.

  An encapsulated product according to the invention is produced by encapsulating the powdered or granular product as described above, which encapsulated product can be used as a hard capsule or as a soft capsule. These capsules may be in the form of powders described above in known capsule materials such as starch, gelatin or beeswax in the same way as in the case of known general capsules. It is produced by filling the product, the granular product or the paste-like product described below and encapsulating them therein.

  The tableted product according to the invention is produced, for example, by compression-molding the granular product produced as described above, for example a rotary-type tablet press. Are preferably used.

  When the health food of the present invention is provided in the form of liquid or paste, for example, horse milk skim milk powder is mixed with milk extract or propolis extract as described above in milk or suspension. Let In this case, an appropriate emulsifier or suspending agent such as sucrose fatty acid ester is used as necessary.

  In order to make the health food of the present invention easy to drink, for example, it may be in the form of a capsule in which a hard capsule of gelatin or starch is filled with the above-mentioned powdery, liquid or paste mixture.

  The products of the present invention listed above alleviate the image of horse milk, which tends to be avoided for consumers unfamiliar with this, or have a strong odor, taste or taste derived from horse milk, straw or propolis. In order to improve the texture and make it easier to consume, at least one of a flavoring agent and a sweetening agent as mentioned above may be added.

  Flavoring agents include, for example, essences derived from fruits such as mandarin orange, lemon, apple or pineapple, and flavoring agents such as vanilla, cacao or coffee, and sweeteners include, for example, sucrose, Examples include glucose or fructose.

The invention's effect

  ADVANTAGE OF THE INVENTION According to this invention, the health supplement food which exhibits various physiological effects, such as an immunity improvement effect | action, an antibacterial and antiviral effect | action, an active oxygen removal effect | action, an anti-inflammatory effect, or an anticancer effect | action, is provided.

  In the following examples, horse milk skim milk produced from horse milk as described above and containing about 3% by weight of water was used.

  A powdery product 1 of the present invention was produced by mixing 200 g of a powder obtained by pulverizing a dried product of Agaricus koji into 200 mesh with 100 g of skim milk powder of horse milk.

  A paste-like product 2 of the present invention was produced by mixing 100 ml of the water extract of Agaricus koji with 80 g of skim milk powder of horse milk.

  The above paste-like product was dried while being exposed to hot air at 40 ° C. to obtain a cake-like dry product, which was then pulverized and sieved with a sieve to give 200 mesh. A powdery product 3 of the present invention was produced.

  Liquid invention product 4 was produced by emulsifying 100 g of skim milk powder of horse milk using 180 g of a water extract of Agaricus koji used in Example 2 using a commercially available emulsifier.

  By suspending 80 g of skim milk powder of horse milk in 120 ml of Brazilian propolis alcoholic extract using a commercially available suspension, liquid product 5 of the present invention was produced.

  A paste-like product 6 of the present invention was produced by mixing 60 ml of the propolis alcohol extract used in Example 5 with 80 g of skim milk powder of horse milk.

  The paste-like product obtained in Example 5 was naturally dried at room temperature to obtain a cake-like dried product, and this dried product was pulverized and sieved with a sieve to obtain 40 mesh. A granular product 7 of the present invention was produced.

  80 g of the propolis alcohol extract used in Example 5 was mixed with 100 g of the powdery product obtained in Example 1 to produce a pasty product 8 of the present invention.

  The paste-like product obtained in Example 8 was naturally dried at room temperature to obtain a cake-like dried product, and then the dried product was pulverized and sieved with a sieve to obtain a 20 mesh A granular product 9 of the present invention was produced.

  A paste-like present invention was prepared by mixing 90 g of the water extract of Agaricus koji used in Example 2 and 60 g of the propolis alcohol extract used in Example 5 with 150 g of skim milk powder of horse milk. Article 106 was manufactured.

  The paste-like product obtained in Example 5 was spray-dried to produce 200-mesh powdery product 11 of the present invention.

  The paste-like product obtained in Example 6 was spray-dried to produce 200-mesh powdery product 12 of the present invention.

  The paste-like product obtained in Example 10 was spray-dried to produce 200-mesh powdery product 13 of the present invention.

  The paste-like product obtained in Example 5 was filled into a hard capsule to produce an encapsulated product 14 of the present invention.

  The paste-like product obtained in Example 10 was filled into a hard capsule to produce Encapsulated Product 15 of the present invention.

  A 79-year-old woman who suffered from colorectal cancer and removed the part extending to the cancer and lymph had metastasized to the lung 3 years after drinking propolis and caused pneumonia. If you start taking 5g of skim milk powder daily, the pneumonia will subside in a week, and a 6cm large tumor is confirmed in the lung. Thereafter, administration of the anticancer agent started, and at the same time, the product of the present invention 10 was also taken together with 5 g daily of skim milk powder of horse milk, and the tumor became smaller as soon as it was seen. It became size.

  Propolis has been taken for some time, but a 60-year-old man diagnosed with early lung cancer started taking 15 grams of skim milk of horse milk per day in addition to this propolis. I found it disappeared. At this time, no cancer virus was detected in the patient's cage.

  A 56-year-old man with collagen disease (polymyositis) started taking propolis with 10g of skim milk powder of horse milk per day after the onset of the disease. I started taking a large amount of medicine (52g per day), but after two months, the amount of this medicine could be reduced to 1/10, and I was taking a large amount of medicine at the time of discharge. Regardless, there was little effect of this drug on the internal organs.

  The dietary supplement according to the present invention effectively heals these diseases and disorders by increasing the natural healing power while maintaining or recovering the physical strength of patients affected by various diseases and disorders as described above. Can be used as a supplement to restore the health of such patients or overcome the obstacles described above.

  It is a block diagram which shows an example of the process for manufacturing skim milk powder of horse milk.

Claims (5)

  A health supplement, comprising at least one selected from salmon, persimmon extract and propolis extract, and skim milk powder of horse milk.   The health supplement according to claim 1, wherein the skim milk powder is produced by spray drying.   The health supplement according to claim 1 or 2, wherein the koji is agaricus koji.   The dietary supplement according to any one of claims 1 to 3, which is powdery, granular, liquid, pasty, or tableted or encapsulated.   The health supplement according to any one of claims 1 to 4, wherein at least one of a flavorant and a sweetener is added.

Images