JP2005047929A5 - - Google Patents
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- Publication number
- JP2005047929A5 JP2005047929A5 JP2004273531A JP2004273531A JP2005047929A5 JP 2005047929 A5 JP2005047929 A5 JP 2005047929A5 JP 2004273531 A JP2004273531 A JP 2004273531A JP 2004273531 A JP2004273531 A JP 2004273531A JP 2005047929 A5 JP2005047929 A5 JP 2005047929A5
- Authority
- JP
- Japan
- Prior art keywords
- use according
- dextrin
- composition
- body cavity
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920001353 Dextrin Polymers 0.000 claims 22
- 239000004375 Dextrin Substances 0.000 claims 22
- 235000019425 dextrin Nutrition 0.000 claims 22
- 239000000203 mixture Substances 0.000 claims 19
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 239000000314 lubricant Substances 0.000 claims 2
- 210000003200 peritoneal cavity Anatomy 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- 238000006116 polymerization reaction Methods 0.000 claims 2
- WCDDVEOXEIYWFB-VXORFPGASA-N (2s,3s,4r,5r,6r)-3-[(2s,3r,5s,6r)-3-acetamido-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-4,5,6-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@@H]1C[C@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](C(O)=O)O[C@@H](O)[C@H](O)[C@H]1O WCDDVEOXEIYWFB-VXORFPGASA-N 0.000 claims 1
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims 1
- 102000005701 Calcium-Binding Proteins Human genes 0.000 claims 1
- 108010045403 Calcium-Binding Proteins Proteins 0.000 claims 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- 229920002683 Glycosaminoglycan Polymers 0.000 claims 1
- 239000000853 adhesive Substances 0.000 claims 1
- 230000001070 adhesive effect Effects 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000013011 aqueous formulation Substances 0.000 claims 1
- 239000011575 calcium Substances 0.000 claims 1
- 229910052791 calcium Inorganic materials 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- KAQKFAOMNZTLHT-VVUHWYTRSA-N epoprostenol Chemical compound O1C(=CCCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 KAQKFAOMNZTLHT-VVUHWYTRSA-N 0.000 claims 1
- 229960001123 epoprostenol Drugs 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 239000003527 fibrinolytic agent Substances 0.000 claims 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 claims 1
- 150000004676 glycans Chemical class 0.000 claims 1
- 229940014041 hyaluronate Drugs 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 229960000907 methylthioninium chloride Drugs 0.000 claims 1
- 230000007935 neutral effect Effects 0.000 claims 1
- 150000003904 phospholipids Chemical group 0.000 claims 1
- 229920001282 polysaccharide Polymers 0.000 claims 1
- 239000005017 polysaccharide Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 1
- 230000008929 regeneration Effects 0.000 claims 1
- 238000011069 regeneration method Methods 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9810127.2A GB9810127D0 (en) | 1998-05-13 | 1998-05-13 | Prevention of surgical adhesions |
| US27271399A | 1999-03-19 | 1999-03-19 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Division JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005047929A JP2005047929A (ja) | 2005-02-24 |
| JP2005047929A5 true JP2005047929A5 (enExample) | 2005-10-06 |
| JP4276601B2 JP4276601B2 (ja) | 2009-06-10 |
Family
ID=26313653
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Expired - Lifetime JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
| JP2004273531A Expired - Lifetime JP4276601B2 (ja) | 1998-05-13 | 2004-09-21 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000548018A Expired - Lifetime JP3679710B2 (ja) | 1998-05-13 | 1999-05-13 | 外科手術上の癒着を阻止するためのデキストリンを含有する組成物 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP1085920B1 (enExample) |
| JP (2) | JP3679710B2 (enExample) |
| CN (1) | CN1181894C (enExample) |
| AT (1) | ATE211002T1 (enExample) |
| AU (1) | AU740832B2 (enExample) |
| BR (1) | BR9911769B8 (enExample) |
| CA (1) | CA2331672C (enExample) |
| DE (1) | DE69900648T2 (enExample) |
| DK (1) | DK1085920T3 (enExample) |
| ES (1) | ES2165735T3 (enExample) |
| IL (2) | IL139283A0 (enExample) |
| NO (1) | NO312709B1 (enExample) |
| NZ (2) | NZ507832A (enExample) |
| PL (1) | PL194109B1 (enExample) |
| PT (1) | PT1085920E (enExample) |
| WO (1) | WO1999058168A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2363713A (en) * | 2000-06-21 | 2002-01-09 | Ml Lab Plc | Dextrin compositions |
| CA2392666C (en) * | 2000-01-21 | 2011-12-13 | Ml Laboratories Plc | Dextrin containing compositions for prevention of adhesions |
| GB0115505D0 (en) * | 2001-06-25 | 2001-08-15 | Britannia Pharmaceuticals Ltd | Prevention of surgical adhesions |
| US8252333B2 (en) * | 2006-01-26 | 2012-08-28 | Jorge Cueto-Garcia | Biodegradable, non-toxic biological adhesive for use in abdominal surgery |
| US8455001B2 (en) | 2007-02-06 | 2013-06-04 | Teijin Limited | Cellulose derivative and method for production thereof |
| DE102008005172A1 (de) * | 2008-01-19 | 2009-07-23 | Mike Ehrlich | Pharmazeutische Zusammensetzung zur Verhinderung von post-operativen Adhäsionen |
| EP2676682A1 (en) * | 2011-02-08 | 2013-12-25 | Jorge Cueto García | Thixotropic biological adhesive for use in internal body cavities |
| US20220265896A1 (en) * | 2019-08-01 | 2022-08-25 | Km Biologics Co., Ltd. | Tissue fibrosis inhibitor in which biocompatible polymer is used |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0207676B1 (en) * | 1985-06-22 | 1994-06-01 | M L Laboratories Plc | Polymers for use in continuous peritoneal dialysis |
| SE457933B (sv) * | 1987-07-06 | 1989-02-13 | Larsson Kare | Farmaceutisk komposition innefattande en vattendispergerad blandning av lipider, monoglycerider och fosfatidylkolin samt dess anvaendning foer framstaellning av en gastronintestinalt verksam kompostion |
| SE8900586L (sv) * | 1989-02-21 | 1990-08-22 | Pharmacia Ab | Komposition och foerfarande foer att foerhindra adhesion mellan kroppsvaevnader |
| US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
| EP0426368B1 (en) * | 1989-10-31 | 1995-01-04 | Howmedica Inc. | Compositions containing derivatives of chitin for preventing adhesion |
| US5318780A (en) * | 1991-10-30 | 1994-06-07 | Mediventures Inc. | Medical uses of in situ formed gels |
| US5614515A (en) * | 1994-11-17 | 1997-03-25 | University Of Southern California | Lazaroid-based compositions and method for preventing adhesion formation using the same |
| US5807833A (en) * | 1995-06-07 | 1998-09-15 | University Of Southern California | Hydroxyethyl starch and use thereof as an absorbable mechanical barrier and intracavity carrier device |
| CA2223590A1 (en) * | 1995-06-07 | 1996-12-19 | The University Of Southern California | Method for reducing or preventing post-surgical adhesion formation using 5-lipoxygenase inhibitors |
| JP3925955B2 (ja) * | 1996-04-26 | 2007-06-06 | 株式会社クラレ | 癒着防止材 |
| IN192791B (enExample) * | 1996-06-28 | 2004-05-22 | Johnson & Johnson Medical |
-
1999
- 1999-05-13 NZ NZ507832A patent/NZ507832A/xx not_active IP Right Cessation
- 1999-05-13 CN CNB998060836A patent/CN1181894C/zh not_active Expired - Lifetime
- 1999-05-13 PL PL99344536A patent/PL194109B1/pl unknown
- 1999-05-13 DE DE69900648T patent/DE69900648T2/de not_active Expired - Lifetime
- 1999-05-13 NZ NZ523994A patent/NZ523994A/en not_active IP Right Cessation
- 1999-05-13 EP EP99920952A patent/EP1085920B1/en not_active Expired - Lifetime
- 1999-05-13 CA CA002331672A patent/CA2331672C/en not_active Expired - Lifetime
- 1999-05-13 PT PT99920952T patent/PT1085920E/pt unknown
- 1999-05-13 DK DK99920952T patent/DK1085920T3/da active
- 1999-05-13 WO PCT/GB1999/001306 patent/WO1999058168A1/en not_active Ceased
- 1999-05-13 ES ES99920952T patent/ES2165735T3/es not_active Expired - Lifetime
- 1999-05-13 IL IL13928399A patent/IL139283A0/xx active IP Right Grant
- 1999-05-13 AU AU38336/99A patent/AU740832B2/en not_active Expired
- 1999-05-13 JP JP2000548018A patent/JP3679710B2/ja not_active Expired - Lifetime
- 1999-05-13 AT AT99920952T patent/ATE211002T1/de active
- 1999-05-13 BR BRPI9911769A patent/BR9911769B8/pt not_active IP Right Cessation
-
2000
- 2000-10-26 IL IL139283A patent/IL139283A/en not_active IP Right Cessation
- 2000-11-01 NO NO20005492A patent/NO312709B1/no not_active IP Right Cessation
-
2004
- 2004-09-21 JP JP2004273531A patent/JP4276601B2/ja not_active Expired - Lifetime
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