JP2005029536A - Milky bathing agent - Google Patents
Milky bathing agent Download PDFInfo
- Publication number
- JP2005029536A JP2005029536A JP2003272669A JP2003272669A JP2005029536A JP 2005029536 A JP2005029536 A JP 2005029536A JP 2003272669 A JP2003272669 A JP 2003272669A JP 2003272669 A JP2003272669 A JP 2003272669A JP 2005029536 A JP2005029536 A JP 2005029536A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- weight
- bath
- parts
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000003287 bathing Methods 0.000 title abstract description 15
- 239000000284 extract Substances 0.000 claims abstract description 89
- 241000207923 Lamiaceae Species 0.000 claims abstract description 37
- 244000042664 Matricaria chamomilla Species 0.000 claims abstract description 19
- 235000007866 Chamaemelum nobile Nutrition 0.000 claims abstract description 9
- 235000007232 Matricaria chamomilla Nutrition 0.000 claims abstract description 8
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 8
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims abstract description 6
- 150000004667 medium chain fatty acids Chemical class 0.000 claims abstract description 5
- 239000013040 bath agent Substances 0.000 claims description 28
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 27
- 239000003788 bath preparation Substances 0.000 claims description 25
- -1 polyoxyethylene Polymers 0.000 claims description 25
- 241001143500 Aceraceae Species 0.000 claims description 13
- 230000000694 effects Effects 0.000 claims description 13
- 239000000341 volatile oil Substances 0.000 claims description 9
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 8
- 239000000194 fatty acid Substances 0.000 claims description 8
- 229930195729 fatty acid Natural products 0.000 claims description 8
- 239000003921 oil Substances 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 240000001548 Camellia japonica Species 0.000 claims description 2
- 239000012675 alcoholic extract Substances 0.000 claims description 2
- 235000018597 common camellia Nutrition 0.000 claims description 2
- 241000208173 Apiaceae Species 0.000 abstract description 2
- 241000208838 Asteraceae Species 0.000 abstract description 2
- 241000533367 Cnidium officinale Species 0.000 abstract 1
- 241001530490 Salvia rosmarinus Species 0.000 abstract 1
- 239000002612 dispersion medium Substances 0.000 abstract 1
- 235000015639 rosmarinus officinalis Nutrition 0.000 abstract 1
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 description 26
- 241000196324 Embryophyta Species 0.000 description 14
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 description 13
- ASKIVFGGGGIGKH-UHFFFAOYSA-N 2,3-dihydroxypropyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(O)CO ASKIVFGGGGIGKH-UHFFFAOYSA-N 0.000 description 12
- 239000000047 product Substances 0.000 description 12
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 description 10
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 7
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 7
- 229940057995 liquid paraffin Drugs 0.000 description 7
- 229960005323 phenoxyethanol Drugs 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 6
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 description 6
- 229940074052 glyceryl isostearate Drugs 0.000 description 6
- VLPFTAMPNXLGLX-UHFFFAOYSA-N trioctanoin Chemical compound CCCCCCCC(=O)OCC(OC(=O)CCCCCCC)COC(=O)CCCCCCC VLPFTAMPNXLGLX-UHFFFAOYSA-N 0.000 description 6
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 239000001683 mentha spicata herb oil Substances 0.000 description 5
- 229960002446 octanoic acid Drugs 0.000 description 5
- 235000019721 spearmint oil Nutrition 0.000 description 5
- 239000001993 wax Substances 0.000 description 5
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 239000000843 powder Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
- 239000003240 coconut oil Substances 0.000 description 3
- 235000019864 coconut oil Nutrition 0.000 description 3
- 238000004821 distillation Methods 0.000 description 3
- 238000004945 emulsification Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 3
- 238000001256 steam distillation Methods 0.000 description 3
- XDOFQFKRPWOURC-UHFFFAOYSA-N 16-methylheptadecanoic acid Chemical compound CC(C)CCCCCCCCCCCCCCC(O)=O XDOFQFKRPWOURC-UHFFFAOYSA-N 0.000 description 2
- LEEDMQGKBNGPDN-UHFFFAOYSA-N 2-methylnonadecane Chemical compound CCCCCCCCCCCCCCCCCC(C)C LEEDMQGKBNGPDN-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 2
- 244000024873 Mentha crispa Species 0.000 description 2
- 235000014749 Mentha crispa Nutrition 0.000 description 2
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 2
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 2
- 230000004913 activation Effects 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 2
- 239000011668 ascorbic acid Substances 0.000 description 2
- 235000010323 ascorbic acid Nutrition 0.000 description 2
- 229960005070 ascorbic acid Drugs 0.000 description 2
- 239000004359 castor oil Substances 0.000 description 2
- 235000019438 castor oil Nutrition 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 238000010411 cooking Methods 0.000 description 2
- NOPFSRXAKWQILS-UHFFFAOYSA-N docosan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCCCCCO NOPFSRXAKWQILS-UHFFFAOYSA-N 0.000 description 2
- UKMSUNONTOPOIO-UHFFFAOYSA-N docosanoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCCC(O)=O UKMSUNONTOPOIO-UHFFFAOYSA-N 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 230000001804 emulsifying effect Effects 0.000 description 2
- 239000000839 emulsion Substances 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 230000016784 immunoglobulin production Effects 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- TZIHFWKZFHZASV-UHFFFAOYSA-N methyl formate Chemical compound COC=O TZIHFWKZFHZASV-UHFFFAOYSA-N 0.000 description 2
- 239000010445 mica Substances 0.000 description 2
- 229910052618 mica group Inorganic materials 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- GLDOVTGHNKAZLK-UHFFFAOYSA-N octadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCCCO GLDOVTGHNKAZLK-UHFFFAOYSA-N 0.000 description 2
- 229940049964 oleate Drugs 0.000 description 2
- 239000002798 polar solvent Substances 0.000 description 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 description 2
- 229920001296 polysiloxane Polymers 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000012264 purified product Substances 0.000 description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 2
- 239000010668 rosemary oil Substances 0.000 description 2
- 229940058206 rosemary oil Drugs 0.000 description 2
- 210000003296 saliva Anatomy 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 description 2
- 239000010936 titanium Substances 0.000 description 2
- 229910052719 titanium Inorganic materials 0.000 description 2
- PROQIPRRNZUXQM-UHFFFAOYSA-N (16alpha,17betaOH)-Estra-1,3,5(10)-triene-3,16,17-triol Natural products OC1=CC=C2C3CCC(C)(C(C(O)C4)O)C4C3CCC2=C1 PROQIPRRNZUXQM-UHFFFAOYSA-N 0.000 description 1
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 description 1
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 description 1
- PAFJZWHXMSQJKV-UQZRNVAESA-N (3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol;octadecanoic acid Chemical compound OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C1OC[C@H](O)[C@H]1O.OC[C@@H](O)C1OC[C@H](O)[C@H]1O.CCCCCCCCCCCCCCCCCC(O)=O.CCCCCCCCCCCCCCCCCC(O)=O PAFJZWHXMSQJKV-UQZRNVAESA-N 0.000 description 1
- ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- FFJCNSLCJOQHKM-CLFAGFIQSA-N (z)-1-[(z)-octadec-9-enoxy]octadec-9-ene Chemical compound CCCCCCCC\C=C/CCCCCCCCOCCCCCCCC\C=C/CCCCCCCC FFJCNSLCJOQHKM-CLFAGFIQSA-N 0.000 description 1
- ZORQXIQZAOLNGE-UHFFFAOYSA-N 1,1-difluorocyclohexane Chemical compound FC1(F)CCCCC1 ZORQXIQZAOLNGE-UHFFFAOYSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- BFPYWIDHMRZLRN-UHFFFAOYSA-N 17alpha-ethynyl estradiol Natural products OC1=CC=C2C3CCC(C)(C(CC4)(O)C#C)C4C3CCC2=C1 BFPYWIDHMRZLRN-UHFFFAOYSA-N 0.000 description 1
- VOXZDWNPVJITMN-ZBRFXRBCSA-N 17β-estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 VOXZDWNPVJITMN-ZBRFXRBCSA-N 0.000 description 1
- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 description 1
- JNAYPSWVMNJOPQ-UHFFFAOYSA-N 2,3-bis(16-methylheptadecanoyloxy)propyl 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCCCCCCCCC(C)C)COC(=O)CCCCCCCCCCCCCCC(C)C JNAYPSWVMNJOPQ-UHFFFAOYSA-N 0.000 description 1
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
- DVVXXHVHGGWWPE-UHFFFAOYSA-N 2-(dimethylamino)benzoic acid Chemical class CN(C)C1=CC=CC=C1C(O)=O DVVXXHVHGGWWPE-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- GECRRQVLQHRVNH-MRCUWXFGSA-N 2-octyldodecyl (z)-octadec-9-enoate Chemical compound CCCCCCCCCCC(CCCCCCCC)COC(=O)CCCCCCC\C=C/CCCCCCCC GECRRQVLQHRVNH-MRCUWXFGSA-N 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- XPFCZYUVICHKDS-UHFFFAOYSA-N 3-methylbutane-1,3-diol Chemical compound CC(C)(O)CCO XPFCZYUVICHKDS-UHFFFAOYSA-N 0.000 description 1
- MIJYXULNPSFWEK-GTOFXWBISA-N 3beta-hydroxyolean-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CCC(C)(C)C[C@H]5C4=CC[C@@H]3[C@]21C MIJYXULNPSFWEK-GTOFXWBISA-N 0.000 description 1
- HIQIXEFWDLTDED-UHFFFAOYSA-N 4-hydroxy-1-piperidin-4-ylpyrrolidin-2-one Chemical compound O=C1CC(O)CN1C1CCNCC1 HIQIXEFWDLTDED-UHFFFAOYSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- 229920000178 Acrylic resin Polymers 0.000 description 1
- 239000004925 Acrylic resin Substances 0.000 description 1
- 208000035285 Allergic Seasonal Rhinitis Diseases 0.000 description 1
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 235000021357 Behenic acid Nutrition 0.000 description 1
- 208000020925 Bipolar disease Diseases 0.000 description 1
- 240000003538 Chamaemelum nobile Species 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- RGHNJXZEOKUKBD-SQOUGZDYSA-M D-gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O RGHNJXZEOKUKBD-SQOUGZDYSA-M 0.000 description 1
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
- 206010012438 Dermatitis atopic Diseases 0.000 description 1
- ZAFNJMIOTHYJRJ-UHFFFAOYSA-N Diisopropyl ether Chemical compound CC(C)OC(C)C ZAFNJMIOTHYJRJ-UHFFFAOYSA-N 0.000 description 1
- JKLISIRFYWXLQG-UHFFFAOYSA-N Epioleonolsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4CCC3C21C JKLISIRFYWXLQG-UHFFFAOYSA-N 0.000 description 1
- BFPYWIDHMRZLRN-SLHNCBLASA-N Ethinyl estradiol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@](CC4)(O)C#C)[C@@H]4[C@@H]3CCC2=C1 BFPYWIDHMRZLRN-SLHNCBLASA-N 0.000 description 1
- 241000282414 Homo sapiens Species 0.000 description 1
- 108010001336 Horseradish Peroxidase Proteins 0.000 description 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 235000004429 Matricaria chamomilla var recutita Nutrition 0.000 description 1
- 241001529735 Melissa Species 0.000 description 1
- 244000245214 Mentha canadensis Species 0.000 description 1
- 235000016278 Mentha canadensis Nutrition 0.000 description 1
- 244000246386 Mentha pulegium Species 0.000 description 1
- 235000016257 Mentha pulegium Nutrition 0.000 description 1
- 235000004357 Mentha x piperita Nutrition 0.000 description 1
- YBRJHZPWOMJYKQ-UHFFFAOYSA-N Oleanolic acid Natural products CC1(C)CC2C3=CCC4C5(C)CCC(O)C(C)(C)C5CCC4(C)C3(C)CCC2(C1)C(=O)O YBRJHZPWOMJYKQ-UHFFFAOYSA-N 0.000 description 1
- MIJYXULNPSFWEK-UHFFFAOYSA-N Oleanolinsaeure Natural products C1CC(O)C(C)(C)C2CCC3(C)C4(C)CCC5(C(O)=O)CCC(C)(C)CC5C4=CCC3C21C MIJYXULNPSFWEK-UHFFFAOYSA-N 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 235000021314 Palmitic acid Nutrition 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 description 1
- 239000004147 Sorbitan trioleate Substances 0.000 description 1
- PRXRUNOAOLTIEF-ADSICKODSA-N Sorbitan trioleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC[C@@H](OC(=O)CCCCCCC\C=C/CCCCCCCC)[C@H]1OC[C@H](O)[C@H]1OC(=O)CCCCCCC\C=C/CCCCCCCC PRXRUNOAOLTIEF-ADSICKODSA-N 0.000 description 1
- 235000021355 Stearic acid Nutrition 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- AWNFRSYMBMFGLK-UHFFFAOYSA-N [2,2-dimethyl-3-(16-methylheptadecanoyloxy)propyl] 16-methylheptadecanoate Chemical compound CC(C)CCCCCCCCCCCCCCC(=O)OCC(C)(C)COC(=O)CCCCCCCCCCCCCCC(C)C AWNFRSYMBMFGLK-UHFFFAOYSA-N 0.000 description 1
- 239000006096 absorbing agent Substances 0.000 description 1
- 125000005210 alkyl ammonium group Chemical group 0.000 description 1
- 150000005215 alkyl ethers Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000008051 alkyl sulfates Chemical class 0.000 description 1
- 239000002280 amphoteric surfactant Chemical group 0.000 description 1
- 239000003945 anionic surfactant Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 239000010426 asphalt Substances 0.000 description 1
- 201000008937 atopic dermatitis Diseases 0.000 description 1
- IRERQBUNZFJFGC-UHFFFAOYSA-L azure blue Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[Al+3].[S-]S[S-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-].[O-][Si]([O-])([O-])[O-] IRERQBUNZFJFGC-UHFFFAOYSA-L 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 229940116226 behenic acid Drugs 0.000 description 1
- 229960000686 benzalkonium chloride Drugs 0.000 description 1
- 239000012965 benzophenone Substances 0.000 description 1
- 150000008366 benzophenones Chemical class 0.000 description 1
- CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 description 1
- 208000028683 bipolar I disease Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 235000019437 butane-1,3-diol Nutrition 0.000 description 1
- 229910000019 calcium carbonate Inorganic materials 0.000 description 1
- 235000013869 carnauba wax Nutrition 0.000 description 1
- 239000004203 carnauba wax Substances 0.000 description 1
- 239000003093 cationic surfactant Substances 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 229940119217 chamomile extract Drugs 0.000 description 1
- 235000020221 chamomile extract Nutrition 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 150000001851 cinnamic acid derivatives Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 229940086555 cyclomethicone Drugs 0.000 description 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 229940105990 diglycerin Drugs 0.000 description 1
- GPLRAVKSCUXZTP-UHFFFAOYSA-N diglycerol Chemical compound OCC(O)COCC(O)CO GPLRAVKSCUXZTP-UHFFFAOYSA-N 0.000 description 1
- 229940008099 dimethicone Drugs 0.000 description 1
- 239000004205 dimethyl polysiloxane Substances 0.000 description 1
- 235000013870 dimethyl polysiloxane Nutrition 0.000 description 1
- JVSWJIKNEAIKJW-UHFFFAOYSA-N dimethyl-hexane Natural products CCCCCC(C)C JVSWJIKNEAIKJW-UHFFFAOYSA-N 0.000 description 1
- SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- KPUWHANPEXNPJT-UHFFFAOYSA-N disiloxane Chemical class [SiH3]O[SiH3] KPUWHANPEXNPJT-UHFFFAOYSA-N 0.000 description 1
- 229960000735 docosanol Drugs 0.000 description 1
- QZUNHWGQSGFRAR-UHFFFAOYSA-N dodecyl octadecanoate;sodium Chemical compound [Na].CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCC QZUNHWGQSGFRAR-UHFFFAOYSA-N 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229960003720 enoxolone Drugs 0.000 description 1
- 229960005309 estradiol Drugs 0.000 description 1
- 229930182833 estradiol Natural products 0.000 description 1
- PROQIPRRNZUXQM-ZXXIGWHRSA-N estriol Chemical compound OC1=CC=C2[C@H]3CC[C@](C)([C@H]([C@H](O)C4)O)[C@@H]4[C@@H]3CCC2=C1 PROQIPRRNZUXQM-ZXXIGWHRSA-N 0.000 description 1
- 229960001348 estriol Drugs 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 229960002568 ethinylestradiol Drugs 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 210000002950 fibroblast Anatomy 0.000 description 1
- 238000005194 fractionation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 229940050410 gluconate Drugs 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229940074774 glycyrrhizinate Drugs 0.000 description 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 description 1
- 150000008282 halocarbons Chemical class 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 1
- FHKSXSQHXQEMOK-UHFFFAOYSA-N hexane-1,2-diol Chemical compound CCCCC(O)CO FHKSXSQHXQEMOK-UHFFFAOYSA-N 0.000 description 1
- 235000001050 hortel pimenta Nutrition 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 150000002430 hydrocarbons Chemical class 0.000 description 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 description 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
- 229940071676 hydroxypropylcellulose Drugs 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 229940074928 isopropyl myristate Drugs 0.000 description 1
- 229940119170 jojoba wax Drugs 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 239000004200 microcrystalline wax Substances 0.000 description 1
- 235000019808 microcrystalline wax Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 229940100540 neopentyl glycol diisostearate Drugs 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 150000002825 nitriles Chemical class 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 229940100243 oleanolic acid Drugs 0.000 description 1
- 229940055577 oleyl alcohol Drugs 0.000 description 1
- XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 description 1
- 239000004006 olive oil Substances 0.000 description 1
- 235000008390 olive oil Nutrition 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- WCVRQHFDJLLWFE-UHFFFAOYSA-N pentane-1,2-diol Chemical compound CCCC(O)CO WCVRQHFDJLLWFE-UHFFFAOYSA-N 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
- 229920000053 polysorbate 80 Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- HZLWUYJLOIAQFC-UHFFFAOYSA-N prosapogenin PS-A Natural products C12CC(C)(C)CCC2(C(O)=O)CCC(C2(CCC3C4(C)C)C)(C)C1=CCC2C3(C)CCC4OC1OCC(O)C(O)C1O HZLWUYJLOIAQFC-UHFFFAOYSA-N 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 235000020944 retinol Nutrition 0.000 description 1
- 239000011607 retinol Substances 0.000 description 1
- 229960003471 retinol Drugs 0.000 description 1
- 239000002151 riboflavin Substances 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000019192 riboflavin Nutrition 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000005063 solubilization Methods 0.000 description 1
- 230000007928 solubilization Effects 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000001593 sorbitan monooleate Substances 0.000 description 1
- 235000011069 sorbitan monooleate Nutrition 0.000 description 1
- 229940035049 sorbitan monooleate Drugs 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 229960005078 sorbitan sesquioleate Drugs 0.000 description 1
- 235000019337 sorbitan trioleate Nutrition 0.000 description 1
- 229960000391 sorbitan trioleate Drugs 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 150000003505 terpenes Chemical class 0.000 description 1
- 235000007586 terpenes Nutrition 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 239000004408 titanium dioxide Substances 0.000 description 1
- 239000011732 tocopherol Substances 0.000 description 1
- 229960001295 tocopherol Drugs 0.000 description 1
- 235000010384 tocopherol Nutrition 0.000 description 1
- 229930003799 tocopherol Natural products 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 description 1
- 229940096998 ursolic acid Drugs 0.000 description 1
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000010497 wheat germ oil Substances 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1
Landscapes
- Cosmetics (AREA)
Abstract
Description
本発明は、浴用剤に関し、更に詳細には、浴槽に投入した場合乳濁する透明溶液の性状である、所謂ミルキータイプの浴用剤に関する。 The present invention relates to a bath agent, and more particularly, to a so-called milky-type bath agent which is a property of a transparent solution that becomes milky when put in a bathtub.
古来より、入浴は種々の効果を生体に及ぼすものであり、日本には湯治という、入浴により各種疾病を治療する習慣が存するし、西欧においても「クアハウス」という制度は、治療行為の一部を負担しており、医療と密着した制度である。この様な入浴の効果を高める手段として、浴用剤を用いることも、又、世界各国で行われていることである。この様な浴用剤は、薬用植物の含有する有効成分を、一様に可溶化、乳化或いは分散させて、体表面全体及び呼気より吸収させる目的で、湯に含有させる製剤であるが、通常、生薬類の有効成分は、精油成分など、水には溶解しにくい成分が多い為、界面活性剤を用いて、可溶化或いは乳化させることが広く行われている。この様な乳化系は、バスタブに投入した際、希釈して乳化されるような設計になっており、この様な特性に適した界面活性剤として、ポリオキシエチレンオレイン酸エステルや、ポリオキシエチレンオレイルエーテルなどの不飽和炭化水素ポリオキシエチレン付加物が用いられている。（特許文献１、特許文献２を参照）更に、セリ科センキュウの抽出物、キク科カミツレの抽出物、シソ科メンタの抽出物或いはシソ科マンネンロウの抽出物も、単独では、この様な入浴剤の有効成分として使用することが知られている。セリ科センキュウの抽出物の、入浴剤に於ける効果としては、リパーゼ活性化作用（例えば、特許文献３参照）、繊維芽細胞活性化作用（例えば特許文献４を参照）、抗体産生抑制作用（例えば、特許文献５を参照）などが存し、キク科カミツレについては、抗体産生抑制作用（例えば、特許文献５を参照）、痩身作用（例えば特許文献６を参照）などが知られているし、シソ科メンタ属の植物については、香料のたちの持続作用（例えば、特許文献７を参照）、温感付与効果（例えば特許文献８を参照）或いは冷感付与作用（例えば特許文献９を参照）等が知られているし、シソ科マンネンロウについては、異臭を抑制する芳香作用（例えば、特許文献１０を参照）や保湿作用（例えば、特許文献１１を参照）などが知られている。しかしながら、１）セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物と２）シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物とを組み合わせて浴用剤に含有させることは全く知られていないし、この様な組合せを含有する浴用剤が、顕著なリフレッシュ効果を有することも全く知られていない。 Since ancient times, bathing has various effects on the living body, and in Japan there is a custom of treating various diseases by bathing called Yuji, and even in Western Europe, the system called `` Kurhaus '' is part of the treatment act It is a system that bears and is closely related to medical care. As a means for enhancing the effect of such bathing, the use of a bath agent is also performed all over the world. Such a bath preparation is a preparation which is contained in hot water for the purpose of uniformly solubilizing, emulsifying or dispersing the active ingredient contained in the medicinal plant and absorbing it from the entire body surface and breath, Since active ingredients of crude drugs are many components that are difficult to dissolve in water, such as essential oil components, solubilization or emulsification using a surfactant is widely performed. Such an emulsifying system is designed to be diluted and emulsified when put into a bathtub, and polyoxyethylene oleate and polyoxyethylene are used as surfactants suitable for such characteristics. Unsaturated hydrocarbon polyoxyethylene adducts such as oleyl ether are used. (See Patent Document 1 and Patent Document 2) Further, an extract of sensaceae, an extract of chamomileaceae, an extract of Labiatae Menta, or an extract of Labiatae Mannenro, such a bath agent alone. It is known to be used as an active ingredient. Examples of the effects of the extract of Aceraceae on bathing agents include a lipase activation action (for example, see Patent Document 3), a fibroblast activation action (for example, see Patent Document 4), an antibody production inhibitory action ( For example, Patent Document 5) is known, and for Compositae chamomile, an antibody production inhibitory action (for example, see Patent Document 5), a slimming action (for example, see Patent Document 6), and the like are known. For plants belonging to the genus Menta, the perfume has a sustained action (see, for example, Patent Document 7), a warm feeling-imparting effect (for example, see Patent Document 8), or a cool feeling-imparting effect (for example, see Patent Document 9). ) And the like, and for Lamiaceae mannen wax, an aroma action (for example, see Patent Document 10) and a moisturizing action (for example, see Patent Document 11) for suppressing a bad odor are known. However, it is quite known that a combination of 1) an extract of Aceraceae and / or an extract of Asteraceae chamomile and 2) an extract of Lamiaceae menta and / or Lamiaceae mannenrou is contained in a bath preparation. It is not known that bath preparations containing such a combination have a significant refreshing effect.
一方、現代社会はストレス社会であり、現代社会での生活においては、かつて人類が経験したことがないほどのストレスが、各個人個人に付加されていると言われている。この様な状況を反映して、躁鬱病或いは総合精神失調症と言った精神疾患の罹患者は急激に増大している。又、過度のストレス負荷は精神のみならず、身体にも影響を及ぼし、アトピー性皮膚炎患者、花粉症患者、自己免疫疾患患者の激増の原因の一つに、この様なストレスがあることも常に指摘されることである。従って、現代社会においては、過剰に負荷されたストレスの影響を速やかに除去し、心身をリフレッシュさせる手段の開発が望まれていると言える。 On the other hand, the modern society is a stress society, and it is said that in the life in the modern society, stress that human beings have never experienced is added to each individual person. Reflecting this situation, the number of people suffering from mental disorders such as manic depression or schizophrenia is increasing rapidly. In addition, excessive stress load affects not only the mind but also the body, and such stress may be one of the causes of abrupt increase in patients with atopic dermatitis, hay fever and autoimmune diseases. It is always pointed out. Therefore, in modern society, it can be said that development of means for quickly removing the influence of excessive stress and refreshing the mind and body is desired.
本発明は、この様な状況下為されたものであり、過剰に負荷されたストレスの影響を速やかに除去し、心身をリフレッシュさせる手段を提供することを課題とする。 The present invention has been made under such circumstances, and it is an object of the present invention to provide means for quickly removing the influence of excessively loaded stress and refreshing the mind and body.
この様な状況に鑑みて、本発明者らは、過剰に負荷されたストレスの影響を速やかに除去し、心身をリフレッシュさせる手段を求めて、鋭意研究努力を重ねた結果、１）セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物と２）シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物を浴用剤に含有させ、これを用いて入浴することにより、かかるストレス緩和が為しうることを見出し、発明を完成させるに至った。即ち、本発明は、以下に示す技術に関するものである。
（１）１）セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物と２）シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物を含有することを特徴とする、浴用剤。
（２）入浴剤が、浴槽に投入した場合乳濁する透明溶液の性状であることを特徴とする、（１）に記載の浴用剤。
（３）セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物において、該抽出物が、アルコール抽出物であることを特徴とする、（１）又は（２）に記載の浴用剤。
（４）シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物において、該抽出物が、精油であることを特徴とする、（１）〜（３）何れか１項に記載の浴用剤。
（５）油剤として、中鎖脂肪酸のトリグリセライドを含有することを特徴とする、（１）〜（４）何れか１項に記載の浴用剤。
（６）界面活性剤として、ポリオキシエチレン脂肪酸グリセリルを含有することを特徴とする、（１）〜（５）何れか１項に記載の浴用剤。
（７）リフレッシュ効果を有することを特徴とする、（１）〜（６）何れか１項に記載の浴用剤。
In view of such a situation, the present inventors have made intensive research efforts to find a means for quickly removing the influence of excessive stress and refreshing the mind and body. And / or an extract of Lamiaceae Menta and / or Lamiaceae mannenro extract in a bath agent, and bathing using this extract can relieve such stress. We found out what could be done and came to complete the invention. That is, this invention relates to the technique shown below.
(1) A bath preparation characterized by containing an extract of Aceraceae and / or an extract of Camellia chamomile and 2) an extract of Lamiaceae menta and / or an extract of Lamiaceae mannenro.
(2) The bath agent according to (1), wherein the bath agent is a property of a transparent solution that becomes milky when put into a bathtub.
(3) The bath preparation according to (1) or (2), wherein the extract is an alcoholic extract in an extract of Aceraceae and / or Asteraceae chamomile.
(4) An extract of Labiatae Menta and / or an extract of Labiatae Mannenrou, wherein the extract is an essential oil, The bath preparation according to any one of (1) to (3), .
(5) The bath agent according to any one of (1) to (4), wherein triglyceride of a medium chain fatty acid is contained as an oil agent.
(6) The bath agent according to any one of (1) to (5), which contains polyoxyethylene fatty acid glyceryl as a surfactant.
(7) The bath agent according to any one of (1) to (6), which has a refreshing effect.
本発明の浴用剤を用いて、入浴することにより、過剰に負荷されたストレスの影響を速やかに除去し、心身をリフレッシュさせ、この影響を取り除くことが出来る。 By taking a bath using the bath preparation of the present invention, it is possible to quickly remove the influence of excessive stress, refresh the mind and body, and remove this influence.
（１）本発明の浴用剤の必須成分であるセリ科センキュウの抽出物及び／又はキク科カミツレの抽出物
本発明の浴用剤は、セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物を含有することを特徴とする。セリ科センキュウとしては、漢方生薬に「川笈」として定義される植物類であれば特段の限定無く適用することが出来る。又、キク科カミツレとしては、ジャーマンカモミール、ローマンカモミール等のカモミール類全体を意味する「カミツレ」に分類される植物であれば特段の限定無く使用することが出来る。ここで、本発明に言う抽出物とは、植物体そのもの、植物体の加工物、植物体乃至は植物体の加工物に溶媒を加えて抽出した物、抽出した物より溶媒を除去した抽出した物の溶媒除去物、抽出した物乃至はその溶媒除去物を分画、精製した精製物、植物体乃至はその加工物を圧搾して得た流分、蒸留乃至は水蒸気蒸留で得た溜分等の何れもが使用可能である。本発明の浴用剤の必須成分である、セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物としては、かかる抽出物の内、抽出した物乃至はその溶媒除去物が好ましい。抽出した物としては、極性の高いい溶剤によって抽出された抽出した物の溶剤除去物が特に好ましく例示できる。極性の高い溶剤としては、ジエチルエーテル、イソプロピルエーテル、テトラヒドロフランなどのエーテル類、塩化メチレン、クロロホルムなどのハロゲン化炭化水素類、酢酸エチル、蟻酸メチルなどのエステル類、アセトンやメチルエチルケトン等のケトン類、アセトニトリルなどのニトリル類、１，３−ブタンジオール、エタノール、イソプロピルアルコールなどのアルコール類、水などが好ましく例示できる。これらの内では、アルコール及び／又は水が特に好ましく、更に好ましいものは水抽出物を更に１５％程度のエタノール水溶液で抽出した抽出物である。この様な抽出物は既に市販されているものが存しそれを利用することが出来る。かかる市販品としては例えば、丸善製薬株式会社より販売されている「センキュウエキス」や「カミツレ流エキス」等が存する。抽出は、植物体に対して１〜１０重量倍の溶剤を加え、室温であれば数日間、沸点付近の温度であれば数時間浸漬すればよい。抽出後は、必要に応じて、減圧濃縮などして溶剤を除去することが好ましい。本発明の浴用剤においては、これらセリ科センキュウの抽出物及びキク科カミツレの抽出物から選択されるものを、唯一種含有することも出来るし、二種以上組み合わせて含有させることも出来る。好ましい形態は、セリ科センキュウの抽出物とキク科カミツレの抽出物と組み合わせて含有させる形態であり、その好ましい含有量としては、総量で１〜１０重量％、更に好ましくは２〜７重量％であり、加えて、それぞれが０．１〜５重量である場合が特に好ましい。
(1) An extract of Aceraceae and / or Asteraceae chamomile extract, which is an essential component of the bath preparation of the present invention. A bath agent of the present invention is an extract of Aceraceae and / or an extract of Asteraceae chamomile. It is characterized by containing. As for the Aceraceae, it can be applied without particular limitation as long as it is a plant that is defined as “Kawabuchi” in herbal medicine. In addition, as the chamomile family chamomile, any plant classified as “chamomile” which means the entire chamomile such as German chamomile and roman chamomile can be used without particular limitation. Here, the extract according to the present invention refers to a plant itself, a processed product of the plant, a product extracted by adding a solvent to the plant or a processed product of the plant, and an extract obtained by removing the solvent from the extracted product. Solvent-removed product, extracted product or purified product obtained by fractionation, purified product, stream obtained by squeezing plant or processed product, fraction obtained by distillation or steam distillation Any of these can be used. As the extract of Aceraceae and / or Asteraceae chamomile, which is an essential component of the bath preparation of the present invention, an extract or a solvent-removed product thereof is preferable. As the extracted product, a solvent-removed product of the extracted product extracted with a highly polar solvent can be particularly preferably exemplified. Highly polar solvents include ethers such as diethyl ether, isopropyl ether and tetrahydrofuran, halogenated hydrocarbons such as methylene chloride and chloroform, esters such as ethyl acetate and methyl formate, ketones such as acetone and methyl ethyl ketone, acetonitrile Preferred examples include nitriles such as 1,3-butanediol, alcohols such as ethanol and isopropyl alcohol, and water. Among these, alcohol and / or water are particularly preferable, and more preferable is an extract obtained by further extracting a water extract with about 15% ethanol aqueous solution. Such an extract already exists on the market and can be used. Examples of such commercially available products include “senkyu extract” and “camomile extract” sold by Maruzen Pharmaceutical Co., Ltd. Extraction may be performed by adding 1 to 10 times the solvent with respect to the plant body and immersing for several days at room temperature and for several hours at a temperature near the boiling point. After extraction, it is preferable to remove the solvent by vacuum concentration or the like, if necessary. In the bath preparation of the present invention, one selected from these extracts of the genus Aceraceae and the extract of the Asteraceae chamomile can be contained alone or in combination of two or more. A preferred form is a form to be contained in combination with an extract of Apiaceae senkyu and an extract of Compositae chamomile, and the preferred content is 1 to 10% by weight, more preferably 2 to 7% by weight. In addition, it is particularly preferred if each is 0.1 to 5 weight.
（２）本発明の浴用剤の必須成分であるシソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物
本発明の浴用剤は、シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物を必須成分として含有することを特徴とする。抽出物の定義は、前記「セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物」における抽出物の定義に準ずるが、シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物としては、揮発成分が好ましく、精油成分が好ましく例示出来る。精油成分は、蒸留乃至は水蒸気蒸留などで得られた非水溶性の溜分或いは植物体を圧搾して得られる流分等が好適に例示出来る。ここで、メンタ属の抽出物としては、スペアミント、ペパーミント、日本ハッカ、メリッサ（ヤマハッカ）等メンタ属に分類される植物の抽出物であれば、特段の限定無く適用することができる。特に好ましいもはスペアミントの精油で、日本薬局方に記載のものが好ましい。又、シソ科マンネンロウの抽出物としても、同様に揮発成分が好ましく、精油成分が好ましく例示出来る。精油成分は、蒸留乃至は水蒸気蒸留などで得られた非水溶性の溜分或いは植物体を圧搾して得られる流分等が好適に例示出来る。これは、メンタ属の植物の抽出物にしても、マンネンロウの抽出物にしてもその香気成分が効果に大きな役目を負っているからである。本発明の浴用剤において、シソ科メンタの抽出物及びシソ科マンネンロウの抽出物から選択されるものとしては、かかる抽出物の内唯一種を含有することも出来るし、二種乃至はそれ以上を組み合わせて含有することも出来る。好ましい形態は、シソ科メンタの抽出物及びシソ科マンネンロウの抽出物の両方を含有する形態である。本発明の浴用剤において、かかるシソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物の好ましい含有量は、総量で、浴用剤全量に対して、０．１〜５重量％であり、更に好ましくは０．５〜３重量％である。又、シソ科メンタの抽出物及びシソ科マンネンロウの抽出物が、それぞれ０．１〜１．５重量％ずつ含有されている形態がより好ましい。
(2) Extract of Lamiaceae Menta and / or Extract of Lamiaceae Mannen wax, which is an essential component of the bath preparation of the present invention, Extract of Lamiaceae Menta and / or Extract of Lenaceae Mannen wax Is contained as an essential component. The definition of the extract is in accordance with the definition of the extract in the above-mentioned “extract of sericaceae extract and / or extract of chrysanthemum family chamomile”, but as the extract of Lamiaceae menta and / or the extract of Lamiaceae mannenro The volatile component is preferable, and the essential oil component can be preferably exemplified. The essential oil component can be preferably exemplified by a water-insoluble fraction obtained by distillation or steam distillation, or a stream obtained by pressing a plant. Here, the extract of the genus Menta can be applied without particular limitation as long as it is an extract of a plant classified into the genus Menta such as spearmint, peppermint, Japanese mint, and Melissa (Yamahakka). Particularly preferred are spearmint essential oils, and those described in the Japanese Pharmacopoeia are preferred. Similarly, the extract of Lamiaceae mannen wax is preferably a volatile component and preferably an essential oil component. The essential oil component can be preferably exemplified by a water-insoluble fraction obtained by distillation or steam distillation, or a stream obtained by pressing a plant. This is because the fragrance component plays a major role in the effect whether it is an extract of the plant belonging to the genus Menta or an extract of Mannenrou. In the bath preparation of the present invention, the extract selected from the Labiatae Menta and the Labiatae Mannenrou may contain only one of these extracts, or two or more of them. It can also be contained in combination. A preferred form is a form containing both a Labiatae Menta extract and a Labiatae Mannenrou extract. In the bath preparation of the present invention, the preferred content of the extract of Lamiaceae Menta and / or the extract of Lamiaceae mannenro is 0.1 to 5% by weight based on the total amount of the bath preparation, Preferably it is 0.5 to 3 weight%. Moreover, the form in which the extract of Lamiaceae Menta and the extract of Lamiaceae mannenrou is 0.1 to 1.5 weight%, respectively is more preferable.
（３）本発明の浴用剤
本発明の浴用剤は、上記シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物を含有することを特徴とする。この様な構成を取ることにより、本発明の浴用剤は、これを用いて入浴したものに対して、このものに過剰に負荷されたストレスの影響を、速やかに除去し、心身をリフレッシュさせる効果を奏する。本発明の浴用剤においては、通常浴用剤や化粧料で使用される任意成分を、かかる必須成分以外に、含有することが出来る、この様な任意成分としては、例えば、スクワラン、流動パラフィン、軽質流動イソパラフィン、重質流動イソパラフィン、マイクロクリスタリンワックス、固形パラフィンなどの炭化水素類、ジメチコン、フェメチコン、シクロメチコン、アモジメチコン、ポリエーテル変性シリコーンなどのシリコーン類、ホホバ油、カルナウバワックス、モクロウ、ミツロウ、ゲイロウ、オレイン酸オクチルドデシル、イソプロピルミリステート、ネオペンチルグリコールジイソステアレート、リンゴ酸ジイソステアレートなどのエステル類、ステアリン酸、ラウリン酸、ミリスチン酸、パルミチン酸、イソステアリン酸、イソパルミチン酸、ベヘン酸、オレイン酸などの脂肪酸類、ベヘニルアルコール、セタノール、オレイルアルコール、オクタデシルアルコールなどの高級アルコール類、ヒマシ油、椰子油、水添椰子油、椿油、小麦胚芽油、イソステアリン酸トリグリセライド、イソオクタン酸トリグリセライド、オリーブオイル等のトリグリセライド類、１，３−ブタンジオール、グリセリン、ジグリセリン、ジプロピレングリコール、ポリエチレングリコール、１，２−ペンタンジオール、１，２−ヘキシレングリコール、イソプレングリコールなどの多価アルコール、ソルビタンセスキオレート、ソルビタンモノオレート、ソルビタントリオレート、ソルビタンセスキステアレート、ソルビタンモノステアレート、ポリオキシエチレンソルビタンモノオレート、ポリオキシエチレンソルビタンモノステアレート、ポリオキシエチレンステアレート、ポリオキシエチレンオレート、ポリオキシエチレングリセリル脂肪酸エステル、ポリエキシエチレンアルキルエーテル、ポリオキシエチレン硬化ヒマシ油等の非イオン界面活性剤、ソジウムラウリルステアレート、ポリオキシエチレンアルキル硫酸塩、スルホコハク酸エステル塩などのアニオン界面活性剤、４級アルキルアンモニウム塩等のカチオン界面活性剤類、アルキルベタイン等の両性界面活性剤類、結晶セルロースや架橋型メチルポリシロキサン、ポリエチレン粉末、アクリル樹脂粉体等の有機粉体類、タルク、マイカ、セリサイト、炭酸マグネシウム、炭酸カルシウム、二酸化チタン、酸化鉄、紺青、群青、チタンマイカ、チタンセリサイト、シリカ等の表面処理されていても良い粉体類、アクリル酸・メタクリル酸アルキルコポリマー及び／又はその塩、カルボキシビニルポリマー及び／又はその塩、キサンタンガムやヒドロキシプロピルセルロースなどの増粘剤、レチノール、レチノイン酸、トコフェロール、リボフラビン、ピリドキシン、アスコルビン酸、アスコルビン酸リン酸エステル塩などのビタミンやグリチルリチン酸塩、グリチルレチン、ウルソール酸、オレアノール酸などのテルペン類、エストラジオール、エチニルエストラジオール、エストリオールなどのステロイド類などの有効成分、フェノキシエタノール、パラベン類、ヒビテングルコネート、塩化ベンザルコニウム等の防腐剤、ジメチルアミノ安息香酸エステル類、桂皮酸エステル類、ベンゾフェノン類などの紫外線吸収剤などが好ましく例示できる。これらの内特に、好ましいものは中鎖脂肪酸のトリグリセライドとポリオキシエチレン脂肪酸グリセリルである。中鎖脂肪酸トリグリセライドとしては、カプリン酸・カプリル酸のトリグリセライドが特に好ましく例示出来る。これは、この成分が、本発明の精油成分の保香効果に優れることと、油剤の中では水への分散性に優れる為、乳濁系に用いた場合、油滴の分散性に優れ、追い炊きしても、湯あかなどを生じにくい為である。又、ポリオキシエチレン脂肪酸グリセリル、好ましくはポリオキシエチレン中鎖脂肪酸グリセリル乃至はポリオキシエチレン分岐脂肪酸グリセリルは、液状で乳化、再乳化性に優れる為、バスタブ中で形成した乳化物の安定性が向上する。又、対追い炊き性も向上する。本発明の浴用剤に於ける中鎖脂肪酸のトリグリセライドの好ましい含有量は、総量で、１〜２０重量％であり、更に好ましくは、５〜１５重量％であり、ポリオキシエチレン脂肪酸グリセリルの好ましい含有量は、総量で５〜２０重量％であり、更に好ましくは１０〜１５重量％である。本発明の浴用剤は、かかる必須成分と、任意成分とを常法に従って処理することにより製造することが出来る。
(3) Bath agent of the present invention The bath agent of the present invention is characterized by containing the extract of the Labiatae Menta and / or the extract of Labiatae Mannen. By taking such a configuration, the bath preparation of the present invention has an effect of quickly removing the influence of stress excessively loaded on this bath and refreshing the mind and body. Play. In the bath preparation of the present invention, optional components usually used in bath preparations and cosmetics can be contained in addition to the essential components. Examples of such optional components include squalane, liquid paraffin, light Hydrocarbons such as liquid isoparaffin, heavy liquid isoparaffin, microcrystalline wax, solid paraffin, silicone such as dimethicone, femethicone, cyclomethicone, amodimethicone, polyether-modified silicone, jojoba oil, carnauba wax, moclaw, beeswax, Esters such as gay wax, octyldodecyl oleate, isopropyl myristate, neopentyl glycol diisostearate, diisostearate malate, stearic acid, lauric acid, myristic acid, palmitic acid, isostearic acid, isopa Fatty acids such as mytic acid, behenic acid, oleic acid, higher alcohols such as behenyl alcohol, cetanol, oleyl alcohol, octadecyl alcohol, castor oil, coconut oil, hydrogenated coconut oil, coconut oil, wheat germ oil, isostearic acid triglyceride, isooctane Triglycerides such as acid triglyceride and olive oil, 1,3-butanediol, glycerin, diglycerin, dipropylene glycol, polyethylene glycol, 1,2-pentanediol, 1,2-hexylene glycol, and isoprene glycol Alcohol, sorbitan sesquioleate, sorbitan monooleate, sorbitan trioleate, sorbitan sesquistearate, sorbitan monostearate, polyoxyethylene sorbitan monooleate Nonionic surfactants such as polyoxyethylene sorbitan monostearate, polyoxyethylene stearate, polyoxyethylene oleate, polyoxyethylene glyceryl fatty acid ester, polyoxyethylene alkyl ether, polyoxyethylene hydrogenated castor oil, sodium lauryl stearate Rate, polyoxyethylene alkyl sulfate, anionic surfactants such as sulfosuccinate ester salts, cationic surfactants such as quaternary alkyl ammonium salts, amphoteric surfactants such as alkyl betaines, crystalline cellulose and cross-linked methylpoly Organic powders such as siloxane, polyethylene powder, acrylic resin powder, talc, mica, sericite, magnesium carbonate, calcium carbonate, titanium dioxide, iron oxide, bitumen, ultramarine, titanium mica, titanium sericite, Powders that may be surface-treated such as silica, acrylic acid / alkyl methacrylate copolymers and / or salts thereof, carboxyvinyl polymers and / or salts thereof, thickeners such as xanthan gum and hydroxypropylcellulose, retinol, retinoin Vitamins such as acid, tocopherol, riboflavin, pyridoxine, ascorbic acid, ascorbic acid phosphate ester, terpenes such as glycyrrhizinate, glycyrrhetin, ursolic acid, oleanolic acid, steroids such as estradiol, ethinyl estradiol, estriol, etc. Active ingredients, preservatives such as phenoxyethanol, parabens, hibiten gluconate, benzalkonium chloride, dimethylaminobenzoic acid esters, cinnamic acid esters, benzophenones Such as UV absorber can be preferably exemplified. Among these, particularly preferred are medium-chain fatty acid triglycerides and polyoxyethylene fatty acid glyceryl. As the medium chain fatty acid triglyceride, capric acid / caprylic acid triglyceride is particularly preferable. This is because this component is excellent in the aroma retaining effect of the essential oil component of the present invention, and is excellent in water dispersibility in the oil, so when used in an emulsion system, it has excellent oil droplet dispersibility, This is because hot water is less likely to occur even after cooking. In addition, since polyoxyethylene fatty acid glyceryl, preferably polyoxyethylene medium chain fatty acid glyceryl or polyoxyethylene branched fatty acid glyceryl is liquid and excellent in emulsification and re-emulsification, stability of the emulsion formed in the bathtub is improved. To do. In addition, the counter-cooking property is also improved. The total content of triglycerides of medium chain fatty acids in the bath agent of the present invention is 1 to 20% by weight in total, more preferably 5 to 15% by weight, and preferable content of polyoxyethylene fatty acid glyceryl. The total amount is 5 to 20% by weight, more preferably 10 to 15% by weight. The bath agent of the present invention can be produced by treating such essential components and optional components according to a conventional method.
以下に、本発明について、実施例を挙げて更に詳細に説明を加えるが、本発明が、かかる実施例にのみ限定されないことは言うまでもない。 Hereinafter, the present invention will be described in more detail with reference to examples, but it is needless to say that the present invention is not limited to such examples.
＜実施例１＞
以下に示す処方に従って、本発明の浴用剤を作成した。即ち、処方成分を８０℃に加熱して、攪拌、可溶化し、攪拌冷却して本発明の浴用剤１を得た。
「センキュウエキス」（丸善製薬株式会社製） １ 重量部
「カミツレ流エキス」（丸善製薬株式会社製） ２．５重量部
スペアミント油 ０．７重量部
ローズマリー油 ０．９重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Example 1>
The bath preparation of the present invention was prepared according to the formulation shown below. That is, the formulation components were heated to 80 ° C., stirred, solubilized, and cooled by stirring to obtain the bath preparation 1 of the present invention.
“Senkyu extract” (manufactured by Maruzen Pharmaceutical Co., Ltd.) 1 part by weight “camomile extract” (manufactured by Maruzen Pharmaceutical Co., Ltd.) 2.5 parts by weight spearmint oil 0.7 part by weight rosemary oil 0.9 part by weight capric acid / capryl Acid triglyceride 5 parts by weight POE (7) (capric / caprylic acid) glyceryl 6 parts by weight POE (20) glyceryl isostearate 7 parts by weight Phenoxyethanol 0.5 parts by weight Liquid paraffin 76.4 parts by weight
＜実施例２＞
実施例１と同様に本発明の浴用剤２を得た。
「センキュウエキス」（丸善製薬株式会社製） １ 重量部
「カミツレ流エキス」（丸善製薬株式会社製） ２．５重量部
スペアミント油 １．６重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Example 2>
The bath agent 2 of the present invention was obtained in the same manner as in Example 1.
“Senkyu extract” (manufactured by Maruzen Pharmaceutical Co., Ltd.) 1 part by weight “camomile style extract” (manufactured by Maruzen Pharmaceutical Co., Ltd.) 2.5 parts by weight spearmint oil 1.6 parts by weight capric acid / caprylic acid triglyceride 5 parts by weight POE (7 ) (Capric acid / Caprylic acid) Glyceryl 6 parts by weight POE (20) Glyceryl isostearate 7 parts by weight Phenoxyethanol 0.5 part by weight Liquid paraffin 76.4 parts by weight
＜実施例３＞
実施例１と同様に本発明の浴用剤３を得た。
「カミツレ流エキス」（丸善製薬株式会社製） ３．５重量部
スペアミント油 ０．７重量部
ローズマリー油 ０．９重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Example 3>
The bath agent 3 of the present invention was obtained in the same manner as in Example 1.
"Kamitsuru style extract" (manufactured by Maruzen Pharmaceutical Co., Ltd.) 3.5 parts by weight spearmint oil 0.7 parts by weight rosemary oil 0.9 parts by weight capric acid / caprylic acid triglyceride 5 parts by weight POE (7) (capric acid / capryl) Acid) glyceryl 6 parts by weight POE (20) glyceryl isostearate 7 parts by weight phenoxyethanol 0.5 part by weight liquid paraffin 76.4 parts by weight
＜実施例４＞
実施例１と同様に本発明の浴用剤４を得た。
「カミツレ流エキス」（丸善製薬株式会社製） ３．５重量部
スペアミント油 １．６重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Example 4>
The bath agent 4 of the present invention was obtained in the same manner as in Example 1.
"Kamitsuru style extract" (manufactured by Maruzen Pharmaceutical Co., Ltd.) 3.5 parts by weight spearmint oil 1.6 parts by weight capric acid / caprylic acid triglyceride 5 parts by weight POE (7) (capric acid / caprylic acid) glyceryl 6 parts by weight POE ( 20) Glyceryl isostearate 7 parts by weight Phenoxyethanol 0.5 part by weight Liquid paraffin 76.4 parts by weight
＜比較例１＞
実施例１と同様に比較例１の浴用剤を得た。
「カミツレ流エキス」（丸善製薬株式会社製） ５．１重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Comparative Example 1>
The bath preparation of Comparative Example 1 was obtained in the same manner as Example 1.
"Kamitsuru style extract" (manufactured by Maruzen Pharmaceutical Co., Ltd.) 5.1 parts by weight Capric acid / Caprylic acid triglyceride 5 parts by weight POE (7) (Capric / Caprylic acid) Glyceryl 6 parts by weight POE (20) Glyceryl isostearate 7 parts by weight Parts Phenoxyethanol 0.5 parts by weight Liquid paraffin 76.4 parts by weight
＜比較例２＞
実施例１と同様に比較例２の浴用剤を得た。
スペアミント油 ５．１重量部
カプリン酸・カプリル酸トリグリセライド ５ 重量部
ＰＯＥ（７）（カプリン酸／カプリル酸）グリセリル ６ 重量部
ＰＯＥ（２０）イソステアリン酸グリセリル ７ 重量部
フェノキシエタノール ０．５重量部
流動パラフィン ７６．４重量部
<Comparative example 2>
The bath preparation of Comparative Example 2 was obtained in the same manner as Example 1.
Spearmint oil 5.1 parts by weight capric acid / caprylic acid triglyceride 5 parts by weight POE (7) (capric / caprylic acid) glyceryl 6 parts by weight POE (20) glyceryl isostearate 7 parts by weight phenoxyethanol 0.5 parts by weight liquid paraffin 76 .4 parts by weight
＜試験例１＞
上記実施例１〜４、比較例１、２の浴用剤について、その効果をパネラーを用いて確かめた。効果は、入浴した翌朝の血液検査の結果より確認した。即ち、パネラー１０名を用い、１週間に１回上記の入浴剤を用いて入浴してもらい、入浴当日の朝、入浴の翌日の朝に血液を採取し、試験受託機関にて、乳酸値、コレステロール量、中性脂肪量を測定してもらった。（試験当日の朝の値−試験翌日の朝の値）／試験当日の朝の値＊１００の計算式より、これらの値の入浴による減少率を求めた。試験は検体を変えて、６回（６週）行った。結果を表１に示す。これより、本発明の浴用剤は比較例の浴用剤に比して、これライ値の減少率が高いことが判る。又、セリ科センキュウの抽出物及び／又はキク科カミツレの抽出物においては、この両者を併用したもののが方が単独使用よりも減少率は高く、シソ科メンタの抽出物及び／又はシソ科マンネンロウの抽出物においては、両者を併用したものの方が単独使用よりも減少率が高く、セリ科センキュウの抽出物、キク科カミツレの抽出物、シソ科メンタの抽出物及びシソ科マンネンロウの抽出物を含む系が最も減少率が高いことが判る。これは、この様な系が、過剰に負荷されたストレスを解除し、疲労を回復せしめている為と勘案される。
<Test Example 1>
About the bath agent of the said Examples 1-4 and the comparative examples 1 and 2, the effect was confirmed using the paneler. The effect was confirmed from the result of blood test the next morning after bathing. That is, 10 panelists were used to bathe with the above bathing agent once a week, and blood was collected on the morning of the bathing day and the day after bathing. They asked me to measure the amount of cholesterol and the amount of neutral fat. From the formula of (morning value on the day of the test-morning value on the next day of the test) / morning value on the day of the test * 100, the decreasing rate of these values by bathing was determined. The test was performed 6 times (6 weeks) with different samples. The results are shown in Table 1. From this, it can be seen that the bath agent of the present invention has a higher reduction rate of the lie value than the bath agent of the comparative example. In addition, in the extract of Aceraceae and / or the extract of Asteraceae chamomile, the combination rate of both is higher than the single use, and the extract of Labiatae Menta and / or Labiatae Mannenrou In the case of the extract of both, the rate of reduction is higher in the case of using both in combination than in the case of using alone, and the extract of the genus Aceraceae, the extract of the Asteraceae chamomile, the extract of the Labiatae Menta and the extract of the Labiatae Mannenro It can be seen that the containing system has the highest reduction rate. This is considered to be because such a system releases the excessive stress and recovers the fatigue.
＜試験例２＞
試験１と同様の手技で、試験当日の朝と、翌朝に唾液を採取し、唾液中のハイドロコルチゾール（ストレス指標）濃度とプラステロン硫酸濃度（快感指標）を測定し減少率を求めた。濃度は、市販の抗体を用いた、サンドウィッチ抗体法によって行った。標識抗体としては、ホースラディッシュペルオキシダーゼ標識抗体を用いた。結果を減少率として、表２に示す。これより、本発明の浴用剤を用いて入浴することにより、ストレス指標が著しく減じ、快感指標が増加することが判る。
<Test Example 2>
Using the same procedure as in Test 1, saliva was collected on the morning and the next morning of the test, and the concentration of hydrocortisol (stress index) and plasterone sulfate (pleasure index) in the saliva were measured to determine the reduction rate. The concentration was determined by the sandwich antibody method using a commercially available antibody. As the labeled antibody, a horseradish peroxidase labeled antibody was used. The results are shown in Table 2 as the reduction rate. From this, it can be seen that by taking a bath using the bath preparation of the present invention, the stress index is remarkably reduced and the pleasure index is increased.
本発明の浴用剤は、過剰に負荷されたストレスを緩和し、リラクゼーションを促す浴用剤に利用出来る。 The bath agent of the present invention can be used as a bath agent that relieves excessive stress and promotes relaxation.
Claims (7)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003272669A JP2005029536A (en) | 2003-07-10 | 2003-07-10 | Milky bathing agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003272669A JP2005029536A (en) | 2003-07-10 | 2003-07-10 | Milky bathing agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005029536A true JP2005029536A (en) | 2005-02-03 |
| JP2005029536A5 JP2005029536A5 (en) | 2006-03-30 |
Family
ID=34210154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003272669A Pending JP2005029536A (en) | 2003-07-10 | 2003-07-10 | Milky bathing agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2005029536A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2883749A1 (en) * | 2005-03-31 | 2006-10-06 | Coletica Sa | Use of a vegetable extract of the family of Compositae or Asteraceae, preferably Cichorium intybus, to tinge cutaneous tissue, preferably to color the tissue to increase the bronzed or gilded aspect of the cutaneous tissue |
| EP1707191A3 (en) * | 2005-03-31 | 2007-08-01 | Engelhard Lyon | Use of plant extracts to dye skin according to its phototype |
| JP2012510513A (en) * | 2008-12-03 | 2012-05-10 | イーエルシー マネージメント エルエルシー | Compositions and methods for promoting relaxation |
| WO2019106750A1 (en) | 2017-11-29 | 2019-06-06 | Kao Corporation | Skin washing method and kit |
-
2003
- 2003-07-10 JP JP2003272669A patent/JP2005029536A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2883749A1 (en) * | 2005-03-31 | 2006-10-06 | Coletica Sa | Use of a vegetable extract of the family of Compositae or Asteraceae, preferably Cichorium intybus, to tinge cutaneous tissue, preferably to color the tissue to increase the bronzed or gilded aspect of the cutaneous tissue |
| EP1707191A3 (en) * | 2005-03-31 | 2007-08-01 | Engelhard Lyon | Use of plant extracts to dye skin according to its phototype |
| US7419688B2 (en) | 2005-03-31 | 2008-09-02 | Engelhard Lyon | Use of plant extracts for tinting the skin as a function of its phototype |
| EP2277502A2 (en) * | 2005-03-31 | 2011-01-26 | BASF Beauty Care Solutions France SAS | Use of plant extracts to dye skin according to its phototype |
| EP2277502A3 (en) * | 2005-03-31 | 2011-05-11 | BASF Beauty Care Solutions France SAS | Use of plant extracts to dye skin according to its phototype |
| JP2012510513A (en) * | 2008-12-03 | 2012-05-10 | イーエルシー マネージメント エルエルシー | Compositions and methods for promoting relaxation |
| WO2019106750A1 (en) | 2017-11-29 | 2019-06-06 | Kao Corporation | Skin washing method and kit |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2011519887A (en) | Cosmetics containing cistus herb extract | |
| CN111132654B (en) | Cosmetic composition with effects of preventing and relieving scalp inflammation and preventing alopecia | |
| JP2008037764A (en) | Sebum secretion inhibitor and skin external preparation for ameliorating acne | |
| TW201422247A (en) | Use of Melicope extracts to improve conditions caused by excess lipids | |
| JP2004196666A (en) | Cosmetic with suppressed stinging | |
| JP2005029536A (en) | Milky bathing agent | |
| JP2008247894A (en) | Stress response ameliorating agent | |
| JP4129388B2 (en) | Multi-layer cosmetic | |
| JP2005029536A5 (en) | ||
| JP6474227B2 (en) | Composition for toiletry products containing plant extract | |
| JP6783512B2 (en) | Topical skin agent | |
| CA2867340A1 (en) | Cosmetic composition | |
| JP3974003B2 (en) | Hair growth material and external preparation for skin containing the same | |
| JP4925750B2 (en) | Cosmetics characterized by a feeling of use | |
| JP2004244370A (en) | External preparation for skin for pimple | |
| JP2005194290A (en) | Cleansing cosmetic | |
| JP2018002677A (en) | Emulsified cosmetic | |
| JP2011037721A (en) | Skin care preparation for external use exhibiting sleep-improving action | |
| JP2004168705A (en) | Preparation for external use for ameliorating skin condition | |
| JP4923076B2 (en) | Milky type bath salt | |
| JP4332380B2 (en) | Milky type bath salt | |
| JP2004182641A (en) | Cosmetic with suppressed stigging | |
| JP4555423B2 (en) | Anti-inflammatory cream | |
| JP2004043345A (en) | Skin care preparation for external use | |
| JP2005206588A (en) | Skin external preparation for preventing acne |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20060214 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20060214 |
|
| RD03 | Notification of appointment of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7423 Effective date: 20060214 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20070417 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20070424 |
|
| A521 | Written amendment |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070625 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20070717 |