JP2005006644A5 - - Google Patents

Info

Publication number

JP2005006644A5

JP2005006644A5 JP2004064913A JP2004064913A JP2005006644A5 JP 2005006644 A5 JP2005006644 A5 JP 2005006644A5 JP 2004064913 A JP2004064913 A JP 2004064913A JP 2004064913 A JP2004064913 A JP 2004064913A JP 2005006644 A5 JP2005006644 A5 JP 2005006644A5

Authority

JP

Japan

Prior art keywords

protein

salt

amino acid

acid sequence

partial peptide

Prior art date

2004-03-09

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 108090000623 proteins and genes Proteins 0.000 claims 29
• 102000004169 proteins and genes Human genes 0.000 claims 27
• 150000003839 salts Chemical class 0.000 claims 21
• 108090000765 processed proteins & peptides Proteins 0.000 claims 14
• 125000003275 alpha amino acid group Chemical group 0.000 claims 11
• 239000002157 polynucleotide Substances 0.000 claims 11
• 102000040430 polynucleotide Human genes 0.000 claims 11
• 108091033319 polynucleotide Proteins 0.000 claims 11
• 238000000034 method Methods 0.000 claims 7
• 150000001875 compounds Chemical class 0.000 claims 6
• 230000014509 gene expression Effects 0.000 claims 6
• 238000012216 screening Methods 0.000 claims 6
• 239000000032 diagnostic agent Substances 0.000 claims 4
• 229940039227 diagnostic agent Drugs 0.000 claims 4
• 239000003814 drug Substances 0.000 claims 4
• 230000002401 inhibitory effect Effects 0.000 claims 4
• 230000030833 cell death Effects 0.000 claims 3
• 230000000694 effects Effects 0.000 claims 3
• 238000004519 manufacturing process Methods 0.000 claims 3
• 102000013455 Amyloid beta-Peptides Human genes 0.000 claims 2
• 108010090849 Amyloid beta-Peptides Proteins 0.000 claims 2
• 230000000692 anti-sense effect Effects 0.000 claims 2
• 230000000295 complement effect Effects 0.000 claims 2
• 230000004770 neurodegeneration Effects 0.000 claims 2
• 208000015122 neurodegenerative disease Diseases 0.000 claims 2
• 239000002773 nucleotide Substances 0.000 claims 2
• 125000003729 nucleotide group Chemical group 0.000 claims 2
• 230000001737 promoting effect Effects 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 150000001413 amino acids Chemical class 0.000 claims 1
• 239000003795 chemical substances by application Substances 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 230000001747 exhibiting effect Effects 0.000 claims 1
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1
• 238000011002 quantification Methods 0.000 claims 1